• Research in Plant Disease
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• v.9 no.3
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• pp.107-115
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• 2003

Chinese yam (Dioscorea opposita cv. Jang-Ma) plants showing necrotic mosaic symptom were collected from their growing fields in Andong, Euisong, Gunwi and Daegu, Korea. Direct negative stainning method by electron microscope showed filamentous particles of about 660 nm in length. Immunosorbent electron microscopy (ISEM) revealed filamentous particles of 660nm decorated with antiserum of Chinese yam necrotic mosaic virus (ChYNMV). The virues purified partially were used to isolate viral RNA as template for RT-PCR to amplify about 1.2 kbp of 3'-terminal region (coat protein, 3'-UTR) with ChYNMV specific and oligo-dT primers. Amino acids sequences of amplified CP genes revealed that the viruses shared 97.9% similarity with ChYNMV (AB044386) wh ich was known as the member of Macluravirus. So the viruses from Chinese yam (D. opposita cv. Jang-Ma) plants were identified as ChYNMV. Comparing the CP amion acid sequences of ChYNMV strains with other macluraviruses such as Cardamon mosaic virus (CdMV), Narcissus latent virus (NLV) and Maclura mosaic virus (MacMV) revealed that N-terminal was the most varialbe region and conserved regions were present within the genus Macluravirus.

• Journal of the Korean Institute of Landscape Architecture
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• v.40 no.5
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• pp.19-32
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• 2012

The purpose of this study is to quantitatively measure the view target and the view area through the selection of landscape control point by selecting Jimyeong-dong Dong-gu and Yeongyeong-dong Buk-gu Daegu, which are planned as the large scale housing complex development area, as the target places. It is very meaningful that from the simulation based on this measurement, the improvement methods are attempted to be suggested at the project level. The results of this study are as follows. First, the total number of viewing targets derived from the literature analysis for the selection of the viewing targets was 24, and finally derived main viewing targets were 4 places. Second, the total number of selection criteria of the derived landscape control point was 15, and these were re-categorized as prospect, accessibility and publicness according to the common property. The preliminary LCPs were selected by measuring the publicness and accessibility, and because of the said measurement, a total of 43 preliminary LCPs were selected. The final LCPs were selected by estimating the prospect of the selected preliminary LCPs, and as a result of estimation, a total of 29 final LCPs were selected. Finally, the total number of evaluation indicators derived from literature analysis was 26. Because of the valuation by the landscape control point, it was found that the 2 view areas were the I grade, 3 areas were II grade and 3 areas were the V grade, the lowest grade among 29 view areas. From the analysis on problems for the improvement methods, 4 improvement-indicators including the diversity of land mosaic were selected for the view area-1 without considering the development project drawing. In addition, for the view area-2 with considering the development project drawing, the landscape as the scenery forests was well formed, and the arrangement of architectures for the security of view corridor was right angle arrangement, and their floor number was 10.

• Journal of health informatics and statistics
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• v.43 no.4
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• pp.307-317
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• 2018

Objectives: This study aimed to verify the effectiveness of Internet-based intervention programs for adults with diabetes by conducting a meta-analysis of studies conducted since 2000. Methods: We conducted a systematic review of research papers published in domestic and overseas journals from January 2000 to December 2015, and selected 9 papers that met the analysis criteria. Data analysis was performed using the open source statistical software R 3.5.0, to analyze the effectiveness of Internet-based interventions on experimental and control groups. Results: The analysis showed that intervention programs for controlling HbA1c levels in adult patients with diabetes most commonly comprised 7 sessions on Internet-based management (77.8%), and the most common frequency of application of intervention programs was 4 session in 6 months (33.4%). The present meta-analysis revealed statistically significant effects of Internet-based intervention activities (SMD = 0.92, 95% CI 0.45-1.40). The analysis of the effect size according to the intervention period showed that the 3-month, 6-month, and 12-month interventions reported in eight studies (89%) had a high effect on the Internet-based intervention group. Conclusions: The results of this study confirm the effectiveness of Internet-based intervention programs for adult patients with diabetes. The need for research on the utilization of Internet-based intervention programs for the steady management of diabetes, a chronic disease; for the development of specific guidelines for intervention activities; and for establishing appropriate protocols are acknowledged.

• Tuberculosis and Respiratory Diseases
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• v.52 no.4
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• pp.309-316
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• 2002

Background: To evaluate the efficacy and toxicity of combination chemotherapy using ifosfamide, cisplatin, and etoposide in patients with advanced non-small cell lung cancer(NSCLC). Materials and methods: Thirty-three patients with inoperable NSCLC(stage IIIb+IV) who had measurable diseases, and had not been treated with chemotherapeutic drugs, were enrolled in this study(from March 1995 to December 1996). The patients received ifosfamide($1500mg/m^2/day$, a full drop with Mesna on days 1-5), Cisplatin ($80mg/m^2/day$ infusion with a hydration on day 2), and Etoposide ($100mg/m^2/day$ infusion for 2 hours on days 1-3). The treatment was repeated every 4 weeks. Results: Ten patients showed a partial responses (30.3%). The overall survival time of the responders was longer than that of the non-responders (median 55 vs 22 weeks, p=0.01). The toxicities of this treatment were tolerable. Grade 3 or 4 leukopenia was observed in 21%. There was 1 death related to febrile neutropenia. The non-hematologic toxicity was mild. The relative dose intensity given to the patients was 0.86 ifosfamide, 0.87 cisplatin, and 0.89 etoposide, showing an average dose intensity of 0.87. Conclusions: A combination regimen of ifosfamide, cisplatin, and etoposide is effective and tolerable for treating advanced non-small cell lung cancer.

• Journal of Rhinology
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• v.25 no.2
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• pp.91-98
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• 2018

Background and Objectives: The present study evaluated the results of skin prick test using 55 allergens at 20 centers in the Republic of Korea in 2006, 2010, and 2014-2015. The aim was to assess changes in the positive rate of allergens according to temporal, regional, and environmental factors. Materials and Method: In total, 20 hospitals were selected based on the population distribution in the Republic of Korea. A skin prick test panel comprising 55 aeroallergens was distributed to 18 hospitals for this prospective study. The 2006 and 2010 skin prick test results were collected and analyzed retrospectively from 20 hospitals, while the 2014/2015 skin prick test results (from June 2014 to May 2015) were collected prospectively from 18 hospitals. Results: A total of 14,897 SPT test results were analyzed: 4,319 in 2006, 7,431 in 2010, and 1,852 in 2014/2015. The overall rate of skin prick test positivity to more than two allergens was significantly higher in males than females. The positive rates of alder pollens and birch, oak and ragweed pollen positivity were increased in older patients. Several positive rates were increased according to the temperature in spring. The positive rates for beech pollen, birch pollen, hazel pollen, oak pollen, Tyrophagus putrescentiae, mugwort, cat, Acarus siro, Lepidoglyphus destructor and Tyrophagus putrescentiae were significantly increased, while those of Cult rye pollen and dandelion were significantly decreased over the three test periods. The overall positive rate for allergens in Jeju province varied significantly from Seoul and other cities. Conclusion: Change in the positive rate of multiple aeroallergens was evaluated in the Republic of Korea over time. Our findings can be used to recommend aeroallergens suitable for inclusion in skin prick test panels in the Republic of Korea and will facilitate further investigation of changes in the patterns of allergic diseases.

• Journal of the Korean Institute of Landscape Architecture
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• v.39 no.4
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• pp.18-27
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• 2011

Recently, the location of urban parks has become more important in terms of the construction of an environment-friendly, sustainable city. To build a refined and desirable urban park, it is necessary to have precise understanding on the evaluation of supply adequacy and selection method for its location. However, there have been few studies on the spatial imbalance and location plan of urban parks. Therefore, this study has attempted to evaluate the spatial imbalance of urban parks in Hwanggeum-dong, Suseong-gu in Daegu and propose a policy suggestion to solve the imbalance. According to the analysis, Hwanggeum 1-dong and 2-dong recorded 943.08$m^2$/GRID and 380.61$m^2$/GRID, respectively, in terms of legal requirements for urban parks and 406,730.80$m^2$ and 157,086.40$m^2$ in terms of total service supply from two neighborhood parks and four children's parks. According to the evaluation of optimal supply area across Hwanggeum-dong, Hwanggeum 1-dong and 2-dong recorded 12.3% and 51.5%, respectively. In an evaluation of the supply adequacy of urban parks, the areas described as 'very satisfying' were 20.5% and 5.4% in Hwanggeum 1-dong and 2-dong, respectively. On the contrary, the areas described as 'very dissatisfying' accounted for 27.6% and 10.8%, respectively, in the two regions. It appears that additional parks should be developed in the inferior areas in terms of urban parks in consideration of various factors such as area and shape. The results of the supply adequacy evaluation will be used as a tool to figure out and solve problems in the location of urban parks and as basic data for a master plan to build an environment-friendly, sustainable city.

• Korean Journal of Community Nutrition
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• v.24 no.3
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• pp.232-244
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• 2019

Objectives: This study evaluated the nutritional status and prevalence of metabolic syndrome of the people who participated in the KNHANES according to the number of household members. They were assessed by using information from the 2013~2014 Korea National Health and Nutrition Examination Survey (KNHANES). Methods: A total of 6,088 persons aged 19 years and over participated in 2013~2014 KNHANES, and they were classified into three groups according to the number of household members (single-person, two-person, three-person & over). The dietary behavior, nutritional status, health-related factors and the prevalence of metabolic syndrome of the subjects were investigated with using information from the survey questionnaires of KNHANES. The nutrient intake data of the subjects were obtained by the 24-hour recall method and this was analyzed for evaluating the nutrition adequacy ratio and the index of nutritional quality. The prevalence of metabolic syndrome among the subjects, and according to the study groups, was estimated using the blood and physical measurement data of the subjects. Results: As for EQ-5D index available for all the health states generated by the EQ-5D descriptive system, the single-person household member was the lowest among all the household types. The index of nutrition quality for protein, crude fiber, calcium, phosphorus, potassium, riboflavin and vitamin C in the single-person household was lower than that of the two-person or the three-person and over households (p<0.001). The mean adequacy ratio of single-person households was significantly decreased compared with that of the other types of households (p<0.001). The prevalence of metabolic syndrome was higher in the single-person households than that in the multiple-person households (p<0.001). Conclusions: These results showed that dietary behaviors, nutrition status and health status might be influenced by the number of household members. The results from this study would be useful for improving Korean people's dietary life and health status by implementing evidence-based, specialized intervention for the members of diverse types of households.