Journal of Rhinology

Korean Rhinologic Society (대한비과학회)
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The Relationship between the Causative Allergens of Allergic Diseases and Environments in Korea Over a 8-Year-Period: Based on Skin Prick Test from 2006 to 2015

  • Park, Chan-Soon (Department of Otorhinolaryngology-Head and Neck Surgery, St. Vincent's Hospital) ;
  • Kim, Boo-Young (Department of Otorhinolaryngology-Head and Neck Surgery, Uijeongbu St. Mary's Hospital) ;
  • Kim, Soo Whan (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul St. Mary's Hospital) ;
  • Lee, Joo Hyung (Department of Otorhinolaryngology-Head and Neck Surgery, Daejeon St. Mary's Hospital, The Catholic University of Korea, School of Medicine) ;
  • Koo, Soo Kweon (Department of Otorhinolaryngology-Head and Neck Surgery, Pusan St. Mary's Hospital) ;
  • Kim, Kyung-Su (Department of Otorhinolaryngology-Head and Neck Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Kim, Seon Tae (Department of Otorhinolaryngology-Head and Neck Surgery, Gachon University, Gil Medical Center) ;
  • Kim, Yong-Dae (Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Yeungnam University) ;
  • Kim, Jeong Hong (Department of Otorhinolaryngology-Head and Neck Surgery, Jeju Hospital, Jeju University, College of Medicine) ;
  • Kim, Jin Kook (Department of Otorhinolaryngology-Head and Neck Surgery, Kun Kook University, School of Medicine) ;
  • Kim, Chang Hoon (Department of Otorhinolaryngology-Head and Neck Surgery, Shinchon Severance Hospital, Yonsei University College of Medicine) ;
  • Kim, Hyun Jun (Department of Otorhinolaryngology-Head and Neck Surgery, Ajou University School of Medicine) ;
  • Kim, Hyo Yeol (Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Rha, Ki-Sang (Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University, School of Medicine) ;
  • Roh, Hwan-Jung (Department of Otorhinolaryngology-Head and Neck Surgery, Pusan National University School of Medicine) ;
  • Park, Dong-Joon (Department of Otorhinolaryngology-Head and Neck Surgery, Yonsei University Wonju College of Medicine) ;
  • Shin, Seung-Heon (Department of Otorhinolaryngology-Head and Neck Surgery, The Catholic University of Daegu, School of Medicine) ;
  • Lim, Sang-Chul (Department of Otorhinolaryngology-Head and Neck Surgery, Chonnam National University Medical School) ;
  • Lee, Jae-Hoon (Department of Otorhinolaryngology-Head and Neck Surgery, Institute of Wonkwang Medical Science, Wonkwang University School of Medicine) ;
  • Lee, Heung Man (Department of Otorhinolaryngology-Head and Neck Surgery, Guro Hospital, Korea University, School of Medicine) ;
  • Lee, Heung Gu (Department of Otorhinolaryngology-Head and Neck Surgery, St. Vincent's Hospital) ;
  • Kim, Young Ha (Department of Otorhinolaryngology-Head and Neck Surgery, Yeouido St. Mary's Hospital) ;
  • Cho, Jin Hee (Department of Otorhinolaryngology-Head and Neck Surgery, Yeouido St. Mary's Hospital)
  • Received : 2018.07.03
  • Accepted : 2018.11.29
  • Published : 2018.11.30
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Abstract

Background and Objectives: The present study evaluated the results of skin prick test using 55 allergens at 20 centers in the Republic of Korea in 2006, 2010, and 2014-2015. The aim was to assess changes in the positive rate of allergens according to temporal, regional, and environmental factors. Materials and Method: In total, 20 hospitals were selected based on the population distribution in the Republic of Korea. A skin prick test panel comprising 55 aeroallergens was distributed to 18 hospitals for this prospective study. The 2006 and 2010 skin prick test results were collected and analyzed retrospectively from 20 hospitals, while the 2014/2015 skin prick test results (from June 2014 to May 2015) were collected prospectively from 18 hospitals. Results: A total of 14,897 SPT test results were analyzed: 4,319 in 2006, 7,431 in 2010, and 1,852 in 2014/2015. The overall rate of skin prick test positivity to more than two allergens was significantly higher in males than females. The positive rates of alder pollens and birch, oak and ragweed pollen positivity were increased in older patients. Several positive rates were increased according to the temperature in spring. The positive rates for beech pollen, birch pollen, hazel pollen, oak pollen, Tyrophagus putrescentiae, mugwort, cat, Acarus siro, Lepidoglyphus destructor and Tyrophagus putrescentiae were significantly increased, while those of Cult rye pollen and dandelion were significantly decreased over the three test periods. The overall positive rate for allergens in Jeju province varied significantly from Seoul and other cities. Conclusion: Change in the positive rate of multiple aeroallergens was evaluated in the Republic of Korea over time. Our findings can be used to recommend aeroallergens suitable for inclusion in skin prick test panels in the Republic of Korea and will facilitate further investigation of changes in the patterns of allergic diseases.

Keywords

Acknowledgement

Supported by : Korea Health Industry Development Institute (KHIDI)

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