• Journal of the Korean Institute of Landscape Architecture International Edition
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• 제1호
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• pp.1-12
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• 2001

The biotope network of Susung gu is characterized as dense residence zones forming its core that enable partial biotope in and around the residential zones. First, in district I, it is possible to make these zones connected to the third district. In district II, which is abundant in biotope, it is very important not to continue destoyi9ng the existing biotopes. In the case of district III, old residence zones have fill the severe gap between forests and the Sinchun river, through redevelopment, which covers more than 30% of the biotope area with large scaled linear residence areas. In the case of district IV, limited destruction of biotope and the improvement of nature areas were suggested as the alternative for preservation of biotopes. Consequently, in the construction of the biotope network in Su-sung gu, the maintenance of existing biotopes is required. Int he old residence zones, as redevelopment occurs, by maintaining biotope area of more than 30% and making the scale of residential complexes more than 1ha, it is possible for old residence zones to accomplish the role of providing important green spaces. In the case of newly developed residential zones, by reducing the rate of pavement of traffic conducts, utilizing small sized parks at the junctions and the plantation of trees along the corridors, the entire residence zones are able to accomplish the role of providing important green space. The problem houses and connecting the inner green space of the private houses with the green spaces of the streets in some areas. Futhermore, green spaces of forests must not be used for urban development. Dual planting on sidewalks, planting plots dispersed among streets and median strips must be established on road, too.

• Molecules and Cells
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• 제43권1호
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• pp.58-65
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• 2020

Fat mass and obesity-associated (FTO) gene helps to regulate energy homeostasis in mammals by controlling energy expenditure. In addition, FTO functions in the regulation of obesity and adipogenic differentiation; however, a role in osteogenic differentiation is unknown. This study investigated the effects of FTO on osteogenic differentiation of C3H10T1/2 cells and the underlying mechanism. Expression of osteogenic and endoplasmic reticulum (ER) stress markers were characterized by reverse-transcriptase polymerase chain reaction and western blotting. Alkaline phosphatase (ALP) staining was performed to assess ALP activity. BMP2 treatment increased mRNA expression of osteogenic genes and FTO. Overexpression of FTO increased expression of the osteogenic genes distal-less homeobox5 (Dlx5) and runt-related transcription factor 2 (Runx2). Activation of adenosine monophosphate-activated protein kinase (AMPK) increased FTO expression, and there was a positive feedback loop between FTO and p-AMPK. p-AMPK and FTO induced mild ER stress; however, tunicamycin-induced severe ER stress suppressed FTO expression and AMPK activation. In summary, FTO induces osteogenic differentiation of C3H10T1/2 cells upon BMP2 treatment by inducing mild ER stress via a positive feedback loop with p-AMPK. FTO expression and AMPK activation induce mild ER stress. By contrast, severe ER stress inhibits osteogenic differentiation by suppressing FTO expression and AMPK activation.

• The Journal of Korean Physical Therapy
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• 제16권4호
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• pp.129-141
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• 2004

The purpose of Lumbar Stabilization is to recover the ability of regulating movement of muscular strength, which currently becomes an essential approach to the treatment for lumbago. Sling exercise is a dynamic exercise and a method of active exercise for the patients to take part in their own treatment. This research is to develop the correlation between Lumbar Stabilization and muscular strength as well as Sling exercise. The subjects of this experiment are 12 healthy and normal male and female lasting for 4 weeks. EMG and Postural Med were used as measuring apparatuses. After experiment of 4 weeks exercises, there was not a meaningful result in the measured result of EMG(P>0.05), But there was a significant increase in the result of Postural Med after the experiment(P<0.05). According to this result, we can find out that there is a significant correlation between Sling exercise and muscular strength as well as Lumbar Stabilization. The increase in the lumbar region augments Lumbar Stabilization and the reaction speed of muscle power. So it recovers the stabilization of spine. This Sling exercise program is efficient for the treatment and prevention of back pain.

• 한국산학기술학회논문지
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• 제21권7호
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• pp.475-486
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• 2020

이 연구는 웹보메트릭스를 활용한 지역관광자원 발굴 및 뉴스 네트워크를 대구 수성구를 중심으로 분석한 연구이다. 데이터는 Bing, Naver 등 웹 데이터를 사용했으며, 네트워크 분석과 댓글 분석을 하였다. 연구문제는 총 세가지로 첫째, 대구 내부에서 수성구의 검색엔진 최적화 수준은 어떠한가? 둘째, 수성구 관광자원의 온라인 출현도는 어떠한가? 셋째, 높은 온라인 출현도를 보이는 관광자원의 뉴스 기사와 댓글은 어떤 내용이 주를 이루는가?이며 그 결과를 보면 첫째, 수성구는 검색엔진 최적화 수준이 대구 내부에서 하위권에 속하며 이는 수성구 관광을 언급한 자료들의 온라인 가시성이 미약한 수준임을 알 수 있다. 둘째, 수성구에서 온라인 출현도가 높은 관광자원들은 대부분 수성못 중심이다. 셋째, 수성못 언론 보도의 내용과 댓글을 살펴본 결과 수성못 교통문제와 열대야가 최대 관심사로 나타나, 관광기반시설에 대한 접근성 개선과 관광자원 개발이 요구된다. 이러한 분석결과는 수성구 관광자원 관련 정책의 개발 및 서비스 운영에 기여 할 수 있고 지역 경제에 대한 해답이 될 것이다.

• East Asian mathematical journal
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• 제27권4호
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• pp.391-415
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• 2011

Mathematics is to reflect on your or other people's psychological mathematic activities. Thus, learners need to reflect on their mathematical activities in order to cultivate mathematical thinking attitude and perceive learning contents. For this study, first of all, two classes of the fifth grade (29 students in experimental group and 31 students in control group) in 'Y' elementary school in Dae-gu city were selected as research targets and post-test of learning achievement and mathematical attitude examination were carried out in order to verify the differences of learning achievement and mathematical attitudes between experimental and control groups. The findings of this study mean that students' learning achievement and mathematical attitudes can be improved by applying mathematical reflective activities to the actual class.

• 한국지역지리학회지
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• 제14권4호
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• pp.367-381
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• 2008

본 연구는 대구시 상업지역의 공간분포 및 계층구조 변화를 분석한 것이다. 분석기법으로 집중지수, 집중화계수 및 특화계수를 이용하였으며, 1985년$\sim$2003년의 기간을 고찰했다. 도시인구의 성장과 함께 도시적 토지이용이 증가되었다. 인구 성장 118%에 비해 상업입지량 증가율은 330%에 달하였다. 주요 상업적 토지이용은 판매업이 가장 높고 그 다음이 업무, 식품 순이다. 업종별 공간 분포의 분석에서 숙박, 의료, 운수창고 및 위락 등이 집중도가 높으며, 도시 외곽으로 갈수록 특수상업지구를 형성하였다. 판매업의 분산화가 가장 높게 나타나고 있으며, 식품, 업무도 분산 성향이 높았다. 한편 분석기간 동안, 도심부의 상업 집중 성향이 나타나고 있다. 도심핵의 공간적 확장과 함께 도심 주변지역의 상업 집중 또한 증가하는 추세이다. 도시상업의 공간구조는 단핵도시의 성격이 강화되고 있다. 그러나 내부시가지의 결절에 2계층의 중심지들이 생성되면서 다핵화의 과정에 있고, 특히 동대구역 역세권 지역은 부도심으로 성장할 잠재력을 나타내고 있다.

• 한국수학사학회지
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• 제33권3호
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• pp.135-154
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• 2020

This paper tries to show the formation of 'Kyungpook School' that is a nickname given to mathematicians of Kyungpook National University (KNU). In the early period, the role of professor Park Jung-gi was the most important drive to set the research tradition. He made Korea's first english journal in mathematics, Kyungpook Mathematical Journal KMJ which became a cornerstone for students to join the international academic community. Professor Ki U-hang published the most amount of papers in Korea in 1970s and became a role model for young scholars. In this background, KNU's Topology and Geometry Research Center at KNU was chosen as the only Science Research Center in mathematics in 1989, and KNU's mathematicians could get a long-period support for capable mathematics researchers' community.

• 한국환경복원기술학회지
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• 제6권5호
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• pp.9-20
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• 2003

The purpose of this study is to construct a database for landscape ecological planning with evaluation and analysis of structure of biotope of city center area for the preservation of species and biotope examining Jung-gu district of Daegu Metropolitan City which is the most extremely and rapidly urbanizing area. The assumption of this study is that the biotope structure of a city center area would be different from the other city area. The results of this study were as follows. 1) The results of the biotope type classification is that there were 11 biotope type groups and 41 detailed biotopes. 2) The primary evaluation is the process for grading general value of classified biotope types, and the result of primary evaluation is that there were 5 biotope types that were greater than third grade besides the biotope type of artificial riverbank with abundant green high water level land. The first grade of biotope type have not appeared in this area, however the fifth grade of biotope type have appeared total of 19 biotope types with the biotope type of the general shopping area with scarce green fields. 3) The secondary evaluation is the process for searching biotopes which are special value, and the result of secondary evaluation is that there were 2 biotopes for la, 7 biotopes for 1b, 2 biotopes for 2a, 1 biotope for 2b and there was no biotope for 2c, and for example, la is the large area that has many magor biotope site in terms of the living space. 4) Finally. scientific method for biotope type classification, the derailed investigation plan of high value biotope and the improvement plan based on the biotope map of city center area must be continued.

• 대한한의학방제학회지
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• 제31권4호
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• pp.231-243
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• 2023

Objectives : Jasminum officinale L. var. grandiflorum is used as a traditional or folk remedy in China to treat arthritis, hepatitis, duodenitis, conjunctivitis, gastritis, and diarrhea. In this study, we aimed to study the hepatocyte protective activity and molecular mechanism of Jasminum officinale L. var. grandiflorum aqueous extract (JGW) using HepG2 hepatocyte cell lines. Methods : HepG2 cells were pretreated with diverse concentrations of JGW, and then the cells were exposed to tert-butyl hydroperoxide (tBHP) for inducing oxidative stress. Hydrogen peroxide (H₂O₂) production, glutathione (GSH) concentration, mitochondrial membrane potential (MMP) and cell viability were measured to investigate hepato-protective effects of JGW. Phosphorylation of AMP-activated protein kinases (AMPK), acetyl coenzyme A carboxylase (ACC) and effects of compound C on cell viability were examined to observe the role of AMPK on JGW-mediated cytoprotection. Results : Pretreatment with JGW (10-300 ㎍/mL) significantly suppressed cytotoxicity induced by tBHP in a concentration dependent manner and reduced the expression of cleaved PARP and cleaved caspase-3 proteins related to apoptosis in HepG2 cells. In addition, pretreatment with JGW significantly prevented the increase in H₂O₂ production, GSH depletion, and lower MMP induced by tBHP. Treatment with JGW (30 minutes of incubation and concentrations of 100 and 300 ㎍/mL) increased the phosphorylation of AMPK and ACC and treatment with compound C, a chemical inhibitor of AMPK, inhibited the cytoprotective effect of JGW. Conclusions : Our results demonstrated that JGW may protect hepatocytes from oxidative stress via activation of AMPK.

• 디지털융복합연구
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• 제19권8호
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• pp.33-42
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• 2021

스마트폰 기반의 관광 플랫폼들이 활성화되면서 리뷰 데이터를 활용한 정책 수립 및 서비스 고도화가 다양한 분야에서 이루어지고 있다. 관광 리뷰 데이터를 활용한 선행연구들의 경우 국내 관광객 중심의 연구가 대다수 수행되었으며, 외국인 관광객 연구의 경우 일부 언어로 수집된 데이터와 텍스트 마이닝 기법에 한정하여 연구가 수행되었다. 이에 본 연구에서는 온라인 리뷰 사이트를 통해 '대구 명소' 키워드를 지정하여 외국인들이 작성한 리뷰 데이터 3,515건을 수집하였다. 그리고 LDA 기반의 토픽모델링을 수행하여 관광 토픽을 도출하였으며, 각 토픽별 전역 및 국지적 공간 분석을 수행한 점이 선행연구와 차별성이라 할 수 있다. 분석 결과 전역적 공간 자기상관이 존재하며, 외국인들이 주로 방문하는 관광지들이 국지적으로 결집되어 있음을 확인하였다. 또한 대다수 토픽에서 중구를 중심으로 핫스팟이 도출되었으며, 분석 결과를 바탕으로 지자체 외국인 관광정책 수립 및 토픽모델링 기반의 공간분석 연구의 기초연구로 활용되길 기대하며, 본 연구의 한계점 또한 제시하였다.