When an active muscle is stretched, its steady-state isometric force following stretch is greater than that of a purely isometric contraction as the corresponding muscle length, referred to as force enhancement (FE). The purpose of this study was to investigate possible effects of muscle architecture on the FE. While subject performed maximal isometric dorsiflexion (REF) and isometric-stretch-isometric dorsiflexion (ECC) contractions, ankle joint angle and dorsiflexion torque using a dynamometer and electromyography of the tibialis anterior and the medical gastrocnemius muscles were measure. Simultaneously, real-time ultrasound images of the tibialis anterior were acquired. Regardless of the speed of stretch of the ECC contractions. the torques produced during the isometric phase following stretch ($37.3{\pm}1.5\;Nm$ ($10{\pm}3%$ FE) and $38.3{\pm}1.5$ ($12{\pm}3%$ FE) for the ECC contractions with $15^{\circ}$/s and $45^{\circ}$/s stretch speeds, respectively) were greater than those of the REF contractions ($34.5{\pm}2.5\;Nm$). Moreover, the amount of FE was found to be stretch speed dependent. Angles of pennation ($\alpha$) during the isometric phase following stretch were the same for the REF ($15{\pm}1^{\circ}$) and the ECC ($14{\pm}1^{\circ}$(LS), $15{\pm}1^{\circ}$(LF)). During the same phase, muscle thicknesses were the same ($14.9{\pm}0.6$, and $14.9{\pm}0.5\;mm$ for the REF and the ECC contractions, respectively). For a large limb muscle, the tibialis anterior muscle, a similar amount of force enhancement was observed as did for other human skeletal muscles. Architectural variables, pennation angle and thickness, were not systematically different between the REF and ECC contractions when FE occurred. Therefore, the results of this study suggest that muscle architecture may have little influence on the production of FE.
Objective : In the present study, the effect of electroacupuncture (EA) applied to several acupoints and non-acupoint in CFA-induced knee arthritis was examined. Methods : A common source of persistent pain in humans is arthritis. Arthritis was induced by injection of CFA $125\;{\mu}l$ into knee joint cavity under enflurane anesthesia. The rat subsequently showed swelling of the ankle and a reduced stepping force of the affected limb for the next several days. The reduced stepping force of the limb was presumably due to a painful knee. EA was applied to either of $LR_2,\;LI_4$, or non-acupoint on the contralateral forelimb for 30 min under gaseous anesthesia. After the termination of EA, behavioral tests measuring stepping force were periodically conducted during the next 4 h. Results : EA applied to $LR_2$ point produced a significant improvement of stepping force of the affected foot lasting for at least 2 h. However, neigher $LI_4$ point nor non-point produced any significant increase of weight bearing force. The improvement of stepping pressure was interpreted as an analgesic effect. The analgesic effect was specific to the acupuncture point since the analgesic effect on CFA-induced knee arthritic pain model could not be mimicked by EA applied to a point, $LI_4$ or non-acupoint. In addition, both NO production and iNOS protein expression increased by arthritis were suppressed by EA applied to $LR_2$ point. Conclusion : These data suggest that EA produces a potent analgesic effect in the rat model of CFA-induced knee arthritis. This analgesic effect is produced by applying EA to an acupoint at opposite side from the painful area in a stimulus point-specific way.
Electronic commerce creates serious problems for tax administration because of difficulties associated with the identification of traders, coding of trade activities and so on. The core issue with respect to resolving tax-related problems in electronic commerce is first, the identification of individual transactions through internet and their contents as well as traders. Secondly, it is the ability of tax authorities to secure effectively such data and information as identifying taxpayers, taxable amount and tax evasion on time. The tax authorities are studying the way to resolve tax evasion associated with electronic commerce by using payment system. Above of all, it is imperative to establish a systematic international cooperation in collecting value added taxes for electronic commerce. In order to enhance the effectiveness of tax system, the authorities of different nations should make joint efforts to collect taxes by exchanging such information as identification and registration of business as well as details of transactions among nations of production and consumption.
Fuel gas is an important energy source that is being increasingly used because of the convenience and clean energy provided. Natural gas is supplied to consumers safely through an underground gas-pipe network made of a polyethylene material. In electrofusion, which is one of the joining methods used, copper wire is used as the heating wire. However, it takes a long time for fusion to occur because the electrical resistance of copper is low. In this study, therefore, electrofusion was conducted by replacing the copper heating wire with carbon fiber to reduce the fusion time and improve the production when joining large pipes. Fusion and tensile tests were performed after the electrofusion joint was made in the polyethylene pipe using carbon fiber. The results showed that the fusion time was shorter and the temperature inside the pipe was higher with an increase in the current value. The ultimate tensile strength of specimens was higher than that of virgin polyethylene pipe, except for polyethylene pipes joined using a current of 0.8 A. The best fusion current value was 0.9 or 1.0 A because of the short fusion time and lack of transformation inside the pipe. Thus, it was shown that carbon fiber can be used to replace the copper heating wire.
This study provides a model of inter-Korean economic cooperation suggesting that economic cooperation should be centered on industrial cooperation. As an independent economic zone, the two Koreas will go through a gradual and functional process of cooperation. Also, economic convergence through 'openness and integration' of both markets is a pre-requisite of successful economic integration on the Korean peninsula. This success of the process requires industrialization of North Korea. This study suggests a model of 'the Corea Industrial Development Community on the Korean Peninsula. It aims to support industrialization of the North Korean economy as well as promotion of South Korea's SME competitiveness. It would help meet the demand for improvement of living conditions of North Korean people. Main policy measures includes: 1) co-effort to develop North Korea's provincial industrial zones, 2) upgrading North Korea's 'Jangmadang' into a highly efficient distribution market. Finally, through the construction of the Joint Industrial Development Zone, it is necessary to create a production sharing module for both Korea's industries.
Objective: We tried to analyze allele-specific expression in the pig neocortex using bioinformatic analysis of high-throughput sequencing results from the parental genomes and offspring transcriptomes from reciprocal crosses between Korean Native and Landrace pigs. Methods: We carried out sequencing of parental genomes and offspring transcriptomes using next generation sequencing. We subsequently carried out genome scale identification of single nucleotide polymorphisms (SNPs) in two different ways using either individual genome mapping or joint genome mapping of the same breed parents that were used for the reciprocal crosses. Using parent-specific SNPs, allele-specifically expressed genes were analyzed. Results: Because of the low genome coverage (${\sim}4{\times}$) of the sequencing results, most SNPs were non-informative for parental lineage determination of the expressed alleles in the offspring and were thus excluded from our analysis. Consequently, 436 SNPs covering 336 genes were applicable to measure the imbalanced expression of paternal alleles in the offspring. By calculating the read ratios of parental alleles in the offspring, we identified seven genes showing allele-biased expression (p<0.05) including three previously reported and four newly identified genes in this study. Conclusion: The newly identified allele-specifically expressing genes in the neocortex of pigs should contribute to improving our knowledge on genomic imprinting in pigs. To our knowledge, this is the first study of allelic imbalance using high throughput analysis of both parental genomes and offspring transcriptomes of the reciprocal cross in outbred animals. Our study also showed the effect of the number of informative animals on the genome level investigation of allele-specific expression using RNA-seq analysis in livestock species.
Precast concrete structures are erected from individual prefabricated components, which are assembled on-site using different types of connections. In the present design of these structures, beam-to-column connections are assumed pin jointed. Bolted billet beam to-column connections have been used in the precast concrete industry for many years. They have many advantages over other jointing methods in component production, quality control, transportation and assembly. However, there is currently limited information concerning their detailed structural behaviour under vertical loadings. The experimental work has involved the determination of moment-relative rotation relationships for semi-rigid precast concrete connections in full-scale connection tests. The study reported in this paper was undertaken to clarify the behaviour of such connections under symmetrical vertical loadings. A series of full-scale tests was performed on sample column for which the column geometry and bolt arrangements conformed to successful commercial practice. Proprietary hollow core floor slabs were tied to the beams by 2T25 tensile reinforcing bars, which also provide the in-plane continuity across the connections. The contribution of the floor strength and stiffness to the flexural capacity of the joint is currently neglected in the design process for precast concrete frames. The flexural strength of the connections in the double-sided tests was at least 0.93 times the predicted moment of resistance of the composite beam and slab. The secant stiffness of the connections ranged from 0.94 to 1.94 times the flexural stiffness of the attached beam. In general, the double-sided connections were found to be more suited to a semi-rigid design approach than the single sided ones. The behaviour of double sided bolted billet connection test results are presented in this paper. The behaviour of single sided bolted billet connection test results is the subject of another paper.
Korean Journal of Construction Engineering and Management
/
v.20
no.3
/
pp.12-21
/
2019
Specification is an important document for securing safe construction and improving quality as well as the contract document. Currently, the specifications used in modular buildings in Korea are only the construction specification, and most of the contents are used by borrowing the standard specifications of the building, so the contents of the modular buildings can not be reflected and it is contents are similar to the guideline book. The current status of domestic specification for modular buildings is affecting the quality of modular buildings. Therefore, we analyze activity through monitoring the modular process of modular buildings and analyze systematically relationship by applying IDEF modeling with analyzed activity. As result this paper proposes a structure of special specification specialized in modular building through generalization. The major classifications were divided into three stages : factory construction, transportation, and on-site installation. The specification structure was divided into 32 types of construction items from the floor slab assembly of the factory production to the joint finish of the on site installation in accordance with the opinion of experts.
Objective: A study was conducted to develop non-dairy creamer analogs/mimics using egg white, egg yolk, soy protein and their combinations, and their nutrient content, shelf-life and flavor acceptability were compared. Methods: Spray dried egg white, egg yolk, and soy protein isolate were purchased from manufacturers and used for the formulae. Results: The protein contents of the non-dairy creamer analogs/mimics were about 8.5% as calculated. The amounts of oleic and linoleic acid content increased as the amount of yolk increased in the formula, but the increases of polyunsaturated fatty acids were <0.5% of total fat. Addition of egg yolk to the formula increased choline and lutein content in the products, but the amounts were <0.4 mg/g for choline and $4{\mu}g/g$ for lutein. The lutein in the products continued to decrease over the storage time, and only about 15% to 20% of the 0-month amounts were left after 3 months of storage. Although the thiobarbituric acid reactive substances values of the spray-dried non-dairy creamer analogs/mimics increased as storage time increased, the values were still low. Yellowness, darkness, and egg flavor/odor of the non-dairy creamer analogs/mimics increased as the amount of egg yolk in the formula increased. The overall acceptability of the non-dairy creamer analogs/mimics was closely related to the intensity of egg flavor/odor, but storage improved their overall acceptance because most of the off-odor volatiles disappeared during the storage. Water temperature was the most important parameter in dissolving spray-dried non-dairy creamer analogs/mimics, and $55^{\circ}C$ to $75^{\circ}C$ was the optimal water temperature conditions to dissolve them. Conclusion: Higher amounts of yolk and soy protein combinations in place of egg white reduced the cost of the products significantly and those products contained better and balanced nutrients than the commercial coffee creamers. However, off-flavor and solubility were two important issues in the products.
In this study, the sales status of female ball-jointed dolls and their parts were investi- gated and analyzed. Baseline data from 194 products and 54 brands on domestic and international Internet sites was gathered for the manufacture of ball-jointed dolls and the development of prototype costumes for them. The results are as follows. First, the sizes used for ball-jointed dolls are SD, USD, MSD, 13SD, and 70SD together with height. This study analyzed 39 sizes (15~70cm) by classifying them into numbered groups: 1 (15~22cm), 2 (23~33cm), 3 (35~51cm), 4 (53~62cm), and 5 (63~70cm). The price varied depending on the size; for example, 50cm dolls were approximately 45,000 won, while limited editions were sold at high prices, regardless of their size. They were classified into designs according to their body proportions and facial features as follows: 7- or 8-head-figure, 5-head figure, and 3-head figure, and were presented proportionally as images of women, adolescents, and infants. Second, the head was incised so that the top could be removed horizontally or the facial region vertically, allowing attachment of the eyeballs (which were either glass, resin, or acrylic) to the inside. More than 30 different colors were sold. Various wig styles were provided, including cut, short hair, and perm. These were made from human hair, heat-resistant fiber, and artificial hair. For the hands, there was a design expressing human hand gestures. For the feet, heels were in the form of wearing either high-heels or flat soles.
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