• Title/Summary/Keyword: Joint diseases

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Effect of Citri Pericarpium ethanol extract on collagen-induced arthritis in mice (진피(陳皮) 에탄올추출물의 콜라겐 유도 관절염 마우스에서의 항관절염 효과 연구)

  • Jung, Jin-Ki;Son, Kun-Ho;Kim, Young-Shik;Park, Yong-Ki
    • The Korea Journal of Herbology
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    • v.26 no.3
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    • pp.1-6
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    • 2011
  • Objectives : The present study was undertaken to determine whether an ethanol extract of Citri Pericarpium (CP-E), which is the pericarp of Citrus unshiu Markovich is efficacious against collagen-induced arthritis (CIA) in mice. Methods : CIA was induced in male DBA/1J mice by intradermal injection of bovine collagen-II in Freund's incomplete adjuvant (IFA). The mice in the onset of arthritis were treated daily with oral administration of CP-E ethanol extract at different doses (50 and 100 mg/kg/bw) for 28 days. Arthritis index, histopathologic changes and the levels of TNF-${\alpha}$ as well as anti-CII IgG in blood were evaluated to confirm the anti-arthritic effect of CP-E on CIA in rats. Results : The results showed that comparing with untreated CIA mice, treated with CP-E extract significantly decreased the arthritic scores and the pathological changes of knee joint tissues, and also reduced the serum levels of TNF-${\alpha}$ and anti-CII IgG in CIA-mice. These results indicate that CP-E extract may effectively alleviate inflammatory response on CIA, and its anti-inflammation can be attributed, at least partially, to the inhibition of proinflamamtory cytokine, TNF-${\alpha}$ in CIA. Conclusions : This study suggest that CP-E has a therapeutic potential in inflammatory joint diseases such as rheumatoid arthritis.

An epidemiological study on the prevalence of temporomandibular disorder and associated history and problems in Nepalese subjects

  • Rokaya, Dinesh;Suttagul, Kanokwan;Joshi, Shraddha;Bhattarai, Bishwa Prakash;Shah, Pravin Kumar;Dixit, Shantanu
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.18 no.1
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    • pp.27-33
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    • 2018
  • Background: Temporomandibular disorder (TMD) represents a subgroup of painful orofacial disorders involving pain in the temporomandibular joint (TMJ) region, fatigue of the cranio-cervico-facial muscles (especially masticatory muscles), limitation of mandible movement, and the presence of a clicking sound in the TMJ. TMD is associated with multiple factors and systemic diseases. This study aimed to assess the prevalence of TMD in Nepalese subjects for the first time. Methods: A total of 500 medical and dental students (127 men and 373 women) participated in this study from May 2016 to September 2016. The Fonseca questionnaire was used as a tool to evaluate the prevalence of TMD, and Fonseca's Anamnestic Index (FAI) was used to classify the severity of TMD. Results: The majority of the participants with TMD had a history of head trauma, psychological stress, and dental treatment or dental problems. The prevalence of TMD in Nepalese students was mild to moderate. Conclusions: The prevalence of TMD in Nepalese subjects was mild to moderate. The majority of the study subjects had eyesight problems, history of head trauma, psychological stress, and drinking alcohol and had received dental treatments.

Diagnostic Application of Temporomandibular Joint Disorder and Ultra Sound Guided Oral &Maxillofacial application (초음파를 이용한 턱관절질환의 진단과 초음파 가이드의 활용)

  • Seong, Tae-Hwan;Park, Jung-Hyun;Kim, Sun-Jong
    • The Journal of the Korean dental association
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    • v.55 no.11
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    • pp.789-799
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    • 2017
  • Ultrasound images are noninvasive, can be observed in real time, have no radiation exposure, do not cause pain, and are not restricted in use depending on the patient's prosthetic implant or medical condition. Since the use of ultrasound in the dental field was first applied for tooth preparation in 1957, the use of diagnostic ultrasound for the first time in 1963 has been reported. Currently, it is used in the diagnosis of soft tissue lesions such as malignant tumor or salivary gland disease, fine needle aspiration test, temporomandibular joint disease, lymph node metastasis, measurement of muscle thickness and inflammatory diseases, differentiation of periapical cyst and granulation tissue, measurement of periodontal tissue thickness. The ultrasound image can be visualized in real time. The clinician can explain the structure to the patient while consulting the patient and consult the patient. When injecting the drug into a specific site or aspirating a specific site or substance, So that it can be confirmed and practiced. Recently, ultrasonic equipment specialized in the dental field has been developed and marketed, and it is expected that the use of ultrasonic waves will become active in the dentistry. In the future, development of popular equipment with size and frequency suitable for dental diagnosis and various researches on maxillofacial ultrasonic anatomy. If clinical studies are continuously carried out to demonstrate efficacy, ultrasound is expected to aid in accurate diagnosis and treatment throughout the dentistry.

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Knee Articular Cartilage Segmentation with Priors Based On Gaussian Kernel Level Set Algorithm (사전정보를 이용한 가우시안 커널 레벨 셋 알고리즘 기반 무릎 관절 연골 자기공명영상 분할기법)

  • Ahn, Chunsoo;Bui, Toan;Lee, Yong-Woo;Shin, Jitae
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39C no.6
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    • pp.490-496
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    • 2014
  • The thickness of knee joint cartilage causes most diseases of knee. Therefore, an articular cartilage segmentation of knee magnetic resonance imaging (MRI) is required to diagnose a knee diagnosis correctly. In particular, fully automatic segmentation method of knee joint cartilage enables an effective diagnosis of knee disease. In this paper, we analyze a well-known level-set based segmentation method in brain MRI, and apply that method to knee MRI with solving some problems from different image characteristics. The proposed method, a fully automatic segmentation in whole process, enables to process faster than previous semi-automatic segmentation methods. Also it can make a three-dimension visualization which provides a specialist with an assistance for the diagnosis of knee disease. In addition, the proposed method provides more accurate results than the existing methods of articular cartilage segmentation in knee MRI through experiments.

Model Construction for Treatment-Seeking Behaviors in Patients with Arthritis (관절염 환자의 치료추구행위 분석에 의한 이론구축 - 병원치료와 민속요법 이용행태 -)

  • Lee, Eun-Ok;Kang, Hyun-Sook;Lee, In-Sook;Eun, Young;Lee, Jong-Soo
    • Journal of muscle and joint health
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    • v.4 no.2
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    • pp.177-196
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    • 1997
  • This study was undertaken to explore the antecedent factors and process of the treatment-seeking behaviors of medical and alternative treatments in patients with arthritis using methodological triangulation. The data were collected from 995 arthritic patients who were registered either in a center of rheumatology for medical treatment or residents of community having no treatment to classify different treatment patterns. Sixteen patients with various types of treatment only, alternative treatment only, and no treatment were selected among the total samples to identify the antecedent factors through in-depth interview. The quantitative data were analyzed by percentile, t-test, chi-square test and discrimant analysis using SAS PC program, while the qualitative data were analyzed by means of grounded theory methodology. Treatment-seeking behaviors of patients change from the early stage to the sick-role stage. At the early stage, initial characteristics of pain and acculturation of medical professionalism affect the choice of treatment patterns. The acculturation of medical professionalism is affected by health care accessibility, level of education, duration of sickness and lay referral system. At the sick-role stage, lay referral system and acculturation of medical professionalism affect the choice of treatment patterns. The acculturation of medical professionalism is affected by characteristics of symtoms, perceived treatment effects, perceived causes of diseases and socio-economic status as well as health care accessibility, level of education and lay referral system. In conclusion, different factors as well as common factors are influencing the treatment-seeking behaviors depending on the disease and treatment stages. More detailed further studies are required to explore the value system or medical acculturation of patients which is one of the most important factors in decision-making about treatment modalities.

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Right Shoulder Pain due to Metastatic Lung Cancer -A case report- (우측 견관절통 치료 중 발견된 전이된 폐암 1예 -증례보고-)

  • Jung, Young Ho;Woo, Seung Hoon;Jeon, Seung Gyu;Lee, Woo Yong;Lim, Yun Hee;Yoo, Byung Hoon
    • The Korean Journal of Pain
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    • v.21 no.2
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    • pp.164-167
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    • 2008
  • Frozen shoulder is known to be a self-limited disease, and it is associated with chronic pain and limitation of joint movement. Although its etiology is still unknown, frozen shoulder is associated with several diseases. The diagnosis is made based on the medical history, the clinical and radiological examinations and exclusion of other shoulder pathologies. The skeleton is one of the most common sites of metastasis in patients with lung cancer. It has been reported that the incidence of bone metastases in lung cancer patients is approximately 30-40%, and the median survival time of patients with such metastases is 6-7 months. We experienced a case of a 77-year-old female patient who complained of right shoulder pain and limited joint mobility, and these symptoms were due to metastatic lung cancer in the shoulder.

Temporo-Mandibular Disorder Syndrome Evaluation by Masseter EMG (교근 근전도 비교를 통한 턱관절 기능장애 평가)

  • Eo, Seungjoon;Jeon, Jinwoo;Yeom, Hojun;Han, Whiejong
    • The Journal of the Convergence on Culture Technology
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    • v.4 no.4
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    • pp.349-354
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    • 2018
  • Human beings have made remarkable advances in medical technology as well as technological advances. However, as was the case in the past, incurable diseases still exist: temporo-mandibular joint (TMJ). The diagnosis of the Korean medical staff, currently called a "medical advance," is adhering to the outdated patient's comments, diagnosis using a doctor's auditory diagnosis and a ruler, and diagnosis of X-ray imaging. Therefore, it is important to have accurate patient symptoms, to have a doctor's own diagnosis and experience, to increase the number of diagnoses due to the severity of the symptoms, and to cover the costs of medical care. To solve this problem, the core conductive signal generated from the bridge was quantified through %MVC. Quantified EMG will be assessed and compared with Cortex to establish a jaw joint condition evaluation criterion.

The Utilization of Dental Hygienists in Oral Healthcare Exchanges between the South and North Korea

  • Ahn, Eunsuk;Han, Ji-Hyoung;Kang, Kyung-Hee;Jang, Young-Eun;Jeon, Ki-Ha;Park, Jeong-Ran
    • Journal of dental hygiene science
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    • v.21 no.1
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    • pp.63-69
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    • 2021
  • Background: This study aimed to identify the role of dental hygienists in exchanges between North and South Korea to lower gaps in the level of dental healthcare between the two countries by conducting a Delphi survey with specialists and identifying alternative policies regarding the utilization of dental hygienists in such exchanges. Methods: Two Delphi surveys were conducted with the participation of nine specialists, and descriptive statistical analyses including mean and standard deviation were performed on the collected data. Results: Among methods of exchange and cooperation regarding oral healthcare under the current North Korean medical system, the issue considered most urgent was the "establishment of oral healthcare infrastructure." The most important short-term strategy was identified as the "selection and formation of partnerships in the field of inter-Korean oral health exchange and cooperation." The mid-term strategy was identified as the "establishment of cooperation in the dental industry, centered on educational cooperation projects." The long-term strategy included "joint R&D projects, oral health surveys, and business development." In order to determine how best to use dental hygienists during inter-Korean exchanges and cooperation, the respondents placed urgency on the "establishment of joint cooperation projects for oral health promotion and early examination and the treatment of dental diseases and planning of community research projects" and "the role of oral health education and media development for residents." Conclusion: Cooperation is necessary regarding the preparation of oral healthcare exchanges that aim to encourage unity between North and South Korea and reduce the gaps between the North and South regarding oral health conditions. Therefore, continuous and reasonable discussions and research are needed regarding the utilization of dental hygienists in such exchanges.

Effect of the Muscle Strength Exercise in Middle Aged People on Risk Factors for Metabolic Syndrome: Using Data from the 8th First Years National Health and Nutrition Examination Survey (2019) (중장년층의 근력운동 실천유무가 대사증후군에 미치는 영향: 제8기 1차 년도 국민건강영양조사(2019년) 자료를 이용하여)

  • Lee, In Young;Kim, Yeon Ha;Yu, Myeong Hwan;Min, Deulle
    • Journal of muscle and joint health
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    • v.29 no.1
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    • pp.1-10
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    • 2022
  • Purpose: Metabolic syndrome is known as a factor that increases the incidence of chronic diseases, such as diabetes and cardiovascular disease. In particular, the metabolic syndrome among a middle-aged population is rapidly increasing from 15.6% to 31.9%. The purpose of this study was to investigate the effect of muscle strength exercise on the metabolic syndrome in middle aged. Methods: This study was a secondary data analysis using National Health and Nutrition Survey 8th, including 2,739 middle aged people (40~64 years old). We used multivariate logistic regression to identify risk factors associated with metabolic syndrome. Statistical analysis was performed using the SPSS 23.0 program. Results: There were 772 patients in the group with metabolic syndrome and 1,967 patients in the non-metabolic syndrome group. The risk of metabolic syndrome was 1.29 times higher in those who did not do muscle strength exercise than those who did exercise (OR=1.29, 95% CI=1.01~1.66). Conclusion: We have found that muscle strength exercise was effective in lowering the risk of developing metabolic syndrome in middle aged. Thus, it is necessary to develop practical muscle strength exercise and education programs.

Patellofemoral contact mechanics after transposition of tibial tuberosity in dogs

  • Park, Donghee;Kang, Jinsu;Kim, Namsoo;Heo, Suyoung
    • Journal of Veterinary Science
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    • v.21 no.4
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    • pp.67.1-67.11
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    • 2020
  • Background: Tibial tuberosity transposition (TTT) causes caudalization of the patellar ligament insertion in canine medial patellar luxation, which can lead to increases in patellofemoral contact pressure. Objectives: The purpose of this study is to confirm the effect of patellofemoral contact mechanics after craniolateral and caudolateral transposition of tibial tuberosity in normal canine hindlimbs. Methods: Craniolateral and caudolateral transposition of tibial tuberosity was performed in 5 specimens, respectively. The pressure was measured in the specimen before TTT, and then in the same specimen after TTT. In this process, data was obtained in 10 specimens. The measurement results were output as visualization data through the manufacturer's software and numerical data through spreadsheet. Based on these 2 data and the anatomical structure of the patellofemoral joint (PFJ) surface, whole measurement area was analysed by dividing into medial, lateral and central area. Results: In craniolateralization of tibial tuberosity, total, medial, central contact pressure was decreased and lateral contact pressure was not statistically changed lateral contact pressure than normal PFJ. In caudolateralization of tibial tuberosity, total, lateral contact pressure was increased and medial contact pressure was not statistically changed than normal PFJ. Although not statistically significant changed, central contact pressure in caudolateralization of tibial tuberosity was increased in all 5 specimens. Conclusions: These results imply that traditional TTT, prone to caudal shift of patellar tendon, can increase retropatellar pressure may lead to various complications and diseases of the stifle joint.