• Title/Summary/Keyword: Joint development

Search Result 1,981, Processing Time 0.029 seconds

Granulocytic Sarcoma(Chloroma) in Leukemic Patients (백혈병 환자의 과립구 육종(녹색종양))

  • Rhee, Seung-Koo;Kang, Yong-Ku;Bahk, Won-Jong;Jung, Yang-Kuk;Lee, Sang-Wook;Jeong, Ji-Ho
    • The Journal of the Korean bone and joint tumor society
    • /
    • v.11 no.1
    • /
    • pp.54-61
    • /
    • 2005
  • Purpose: The granulocytic sarcoma which developed in leukemic patients are quite rare and it will have bad prognosis, but it's tumor pathogenesis and also their treatment are not yet established. Through this study we have tried to know their clinical course, prognosis and their end result of recent treatment. Material and Methods: Total 20 patients of granulocytic sarcoma which were developed in total 2,197 leukemic patients from April, 1998 to September, 2004 were treated at the leukemic center and the orthopaedic department of St. Mary's hospital, Catholic University of Korea, and followed them for 1~78 months(average 18 months). Results: Total 20 cases of granulocytic sarcoma was found in 14 cases of total 1,331 acute myelocytic leukemic patients(AML), 4 cases of total 744 of chronic myelocytic leukemic patients(CML), and only one case in total 122 of acute biphenotype of leukemia. And so their occurrence rate in leukmic patients are actually 0.91%, total 20 cases of granulocytic sarcoma in total 2,197 leukemic patients at same period. Their ages are average 28.3 years(4~52 years), and male are predominant(13 cases) than female(7 cases). Single involvement was found in 11 cases but multiple lesions are in 9 cases, and spine, brain, extremities, chest, and pelvic bone are involved in frequency. The granulocytic sarcoma was developed in various stages of the leukemia, ie, 8 cases in complete remission of leukemia, and 12 cases in the treatment process of AML. The pathohistologic evaluation of granulocytic sarcoma was done in 6 cases which was developed in their extremities, and confirmed numerous immature myeloblasts and lymphocytes mixed. The treatment of these granulocytic sarcoma was mainly limited for the treatment of leukemia by Glivac and massive steroid therapy(19cases) and also combined with the bone marrow transplantation(13 cases), but radiation therapy with average 3,500 rads in 15 cases out of total 20 sarcomas was also done, and followed them for average 17.5 months after development of granulocytic sarcomas. Finally their prognosis was so bad that 12 patients(60%) out of total 20 granulocytic sarcoma were dead in 6.5 months after sarcoma developed and we found the granulocytic sarcoma was more fatal if they are developed during the process of CML(mortality: 100%(4/4cases). Conclusion: The prognosis of granulocytic sarcomas in leukemic patients are quite fatal, and much more studies for their pathogenesis and ways of treatment should be performed continuously.

  • PDF

Governance in Dongnam Region and Regional Development : The Case of Dongnam Regional Development Committee (동남경제권 거버넌스와 지역발전 - 동남권광역경제발전위원회를 중심으로 -)

  • Kwon, Ohyeok
    • Journal of the Korean association of regional geographers
    • /
    • v.21 no.3
    • /
    • pp.450-460
    • /
    • 2015
  • Metropolitan-wide economic region policy which was enforced by Lee Myeongbak government was a timely policy at least to Dongnam region. However, examining the activities and outcomes of Dongnam Regional Development Committee, there are many doubts about the policy as metropolitan-wide governance. Dongnam Regional Development Committee had many operational problems. It had few independent labor force and low budget. Also its authority was limited. Above all, its purpose and function was unclear. As a result, the policy was abolished as new government suceeded. Henceforth Dongnam region needs metropolitan-wide governance for metropolitan-wide economic development. If an organization which supports industrial and regional development of Dongnam region would be reestablished, the orientation of governance has to be determined. In this case, the main function of the organization would be researching about Dongnam metropolitan-wide economic region, and suggesting and recommending metropolitanwide development strategy. For the benchmark of the organization, Metropolitan Planning Organization of the US, Joint Venture at Silicon Valley and Regio Randstad of the Netherlands would be appropriate. Above organizations receive budgets from central and regional government and private sector. They research about regional economics and urban development which is comprehensive and metropolitan-wide and could not be done by local government alone.

  • PDF

Study on the Improvement of Relevant Legislative System for Activating Research Equipment Industry (연구장비산업 활성화를 위한 관련 법제 개선방안에 대한 연구)

  • Baek, Woonil;Han, Gapun
    • The Journal of Society for e-Business Studies
    • /
    • v.25 no.2
    • /
    • pp.127-146
    • /
    • 2020
  • Overseas advanced countries are aware of the importance of research equipment and are providing a lot of policy support to revitalize the research equipment industry. However, Korea does not have any law to support policies or related projects to revitalize the research equipment industry. Therefore, there is an urgent need for legislation to support policies and projects for revitalizing research equipment industry. It is considered necessary to establish a separate special law for revitalizing the research equipment industry so that it can gain competitiveness in the global market of the research equipment industry. As we have seen, the necessary articles in the relevant laws should be specified so that various promotion policies can be developed to foster the research equipment industry. In order to promote the development of research equipment industry, there are three essential items to be specified in the law. First is research and development support, second is infrastructure development, and third is business incubation. The following contents should be included in each contents. First of all, "research and development support" includes research and envelopment project promotion and support policy items, research equipment development trends and investment trends, joint research between industry, academia, And research and development support for fusion, hybrid and commercialization. Next, the items to be included in "infrastructure development" should include the establishment of research equipment clusters, related support items, training of professional manpower, and research equipment development base area and institutions. Finally, the items that should be included in "business incubation." include support matters for the development of excellent companies (priority purchase system, etc.), matters related to technology transfer and marketing, matters concerning the protection of intellectual property, And matters for promoting overseas expansion.

A Review of Salvage Archaeology in Korea and a Joint Research and Excavation Plan for North Korean Cultural Heritage (남북 문화유산 조사 현황과 공동조사를 위한 제언)

  • Choi, Jongtaik;Seong, Chuntaek
    • Korean Journal of Heritage: History & Science
    • /
    • v.52 no.2
    • /
    • pp.20-37
    • /
    • 2019
  • Three Inter-Korea summits and a North Korea-USA summit that were previously unexpected provide a basis for an optimistic outlook for the future development of Korean archaeology. While Korean archaeology has witnessed a great advance since the mid-20th century, it also exhibits significant weaknesses in explaining cultural changes in prehistory and the early historical period in the Korean Peninsula due to the paucity of information on archaeological evidence of North Korea. Recent development of favorable conditions for research and excavations of North Korean cultural heritage could be a valuable opportunity for Korean archaeology to overcome the current adversity. Especially, given the expected large-scale SOC industrial project in North Korea, we need to prepare for the systematic research and excavation of archaeological materials. The present essay attempts to provide a suggestion for the joint archaeological expeditions to excavate and manage cultural resources in North Korea based on a critical review of previous salvage excavations in South Korea, such as those conducted before the construction of the Korean rapid transit railway system (KTX). We suggest that professional archaeologists should be included in the project and oversee the planning and design of road and railway constructions and other SOC projects in order to minimize the cost of trial and error processes that were well exemplified by the KTX salvage excavations. The Korean Archaeological Society and North Korean Archaeological Society may organize a common association that will supervise joint archaeological expeditions. Importantly, The Korean Archaeological Society and other related institutions should prepare to build an organization that conducts impending archaeological excavation in North Korea. While we likely face challenges and difficulties during the various stages of archaeological research and excavations in North Korea, only through thorough and systematic preparation can we avoid the destruction of valuable cultural heritage and find an opportunity for the further development of Korean archaeology.

Development of Multi-rotational Prosthetic Foot for Lower Limb Amputee (하지 절단자를 위한 다축 회전이 가능한 인공발의 개발)

  • Shin, Hyunjun;Park, Jin-Kuk;Cho, Hyeon-Seok;Ryu, Jei-Cheong;Kim, Shin-Ki
    • Journal of rehabilitation welfare engineering & assistive technology
    • /
    • v.10 no.4
    • /
    • pp.305-313
    • /
    • 2016
  • Movements of the lower limb are important for normal walking and smooth oscillation of the center of gravity. The ankle rotations such as dorsi-flexion, plantar-flexion, inversion and eversion allows the foot to accommodate to ground during level ground walking. Current below knee (B/K) prostheses are used for replacing amputated ankle, and make it possible for amputees to walk again. However, most of amputees with B/K prostheses often experience a loss of terrain adaptability as well as stability because of limited ankle rotation. This study is focused on the development of multi-rotational prosthetic foot for lower limb amputee. Our prosthesis is possible for amputees to easily walk in level ground by rotating ankle joint in sagittal plane and adapt to the abnormal terrain with ankle rotation in coronal plane. The resistance of ankle joint in the direction of dorsi/plantar-flexion can be manually regulated by hydraulic damper with controllable nozzle. Furthermore, double layered rubber induce the prosthesis adapt to irregular ground by tilting itself in direction of eversion and inversion. The experimental results highlights the potential that our prosthesis induce a normal gait for below knee amputee.

Comparative Study of Square-Inventory Method with Scanline Survey in Slope Stability Analysis (사면 안정 분석을 위한 정면적법과 선조사법의 비교연구)

  • Cheong, Sang-Won;Choi, Byoung-Ryol
    • The Journal of Engineering Geology
    • /
    • v.19 no.2
    • /
    • pp.119-129
    • /
    • 2009
  • In relation to slope stability analysis, geologic characteristics and engineering properties of the discontinuities in three slopes selected are compared and analyzed by both square-inventory method and scanline survey. The aim of the study is in evaluating which method is applied better in slope stability analysis by comparing results of the two methods with those of direct observation on outcrop of slope failures generated. In each slope, results of comparative analysis among geologic and engineering properties are analyzed similarly one another. However, results of orientation analysis in slope 2 are different each other, which indicates orientation of joints in slope 2 depends on persistency and frequency of each joint and also indicates appearance of new joint set with different orientation. Probability density distribution and spacing in slope 3 are high in comparison to those in slope 2 and 3. The reasons are that distribution of psammitic rocks and development of minor folds in slope 3 unlike slope 2 and 3 are closely associated with development of joints. The research data indicate that the square-inventory method predicts more precise failure aspects and is more effective way than scanline survey in analyzing slope stability of the study area.

Acute Occlusal Change Following Acute Anterior Disc Displacement without Reduction: A Case Report (급성 비정복성 관절원판 변위에 따른 급성 교합변화의 증례)

  • Jung, Jae-Kwang;Hur, Yun-Kyung;Choi, Jae-Kap
    • Journal of Oral Medicine and Pain
    • /
    • v.37 no.4
    • /
    • pp.205-211
    • /
    • 2012
  • A 35 year-old female presented with the complaint of sudden occurrence of bite change and concurrent opening limitation, as well as pain in the right temporomandibular joint (TMJ) during mouth opening. From her history it was revealed that she had simple clicking of right TMJ for several years before onset of these symptoms, and that the clicking sound subsided recently after development of opening limitation. On clinical examination, anterior open bite, midline shift of the mandible to right, and premature contacts on left posterior teeth were observed. Maximum mouth opening and lateral movement to left were also restricted. On magnetic resonance images, the right TMJ showed anterior disc displacement without reduction and the posterior joint space is greatly collapsed by retrusion of the condyle. It was thought that the sudden occurrence of occlusal change would be resulted from abrupt displacement of the mandible associated with development of the anterior disc displacement without reduction. The stabilization appliance traction therapy was performed initially for first 3 months along with physical and pharmacologic therapy. However, the anterior open bite and opening limitation didn't resolve and the position of mandible still remained altered. So the stabilization appliance was changed to intermaxillary traction device. Then the mandible returned progressively to normal position and the occlusion became more stable and comfortable. After 5 months of intermaxillary traction therapy, the anterior open bite was dissolved completely and the occlusion became stabilized satisfactorily along with recovery of normal mouth opening range. On post-treatment magnetic resonance image, remodeling of condylar head was observed.

Study on the Extension of Reinforced Concrete Slabs (철근콘크리트 바닥판 평면확장 공법에 대한 연구)

  • Kim, Jin-Pyeng;Kim, Sang-Sik;Choi, Kwnag-Ho;Jeon, Byong-Gap;Lee, Jung-Yoon
    • Journal of the Korea Concrete Institute
    • /
    • v.18 no.3 s.93
    • /
    • pp.321-330
    • /
    • 2006
  • In order to remodel old aged reinforced concrete buildings, it is often required to extend the residence area of the buildings by increasing the slab area. The slab area is usually extended by attaching a new slab to the existing slab with hinged joint or rigid joint. Transmission of the loads of the attached slabs to the existing slabs depends on the connecting methods, such as hinged or rigid connection. In this research, 8 specimens and 24 RC slabs connected by rigid joints were tested. The new slab was connected to the existing slab by three types of rigid joints using dowel bars and longitudinal tensile bars. Main parameters of the slabs were three types of the rigid joints, anchor length of steel bars(0, 50, 60, 100, and 120mm), development length of steel bars(100, 200, and 300mm), and the spacing of the steel bars(150, 200, 300, and 450mm). The test results indicated that the flexural strength of the RC test slabs having various types of rigid joints was approximately the same to that of the slab without any connections.

The examination of application possibility and development of new welding joint shape for aluminum alloy (Al어선 선체용접부의 신형상 개발 및 적용 가능성 검토)

  • Jong-Myung Kim;Chong-In Oh;Han-Sur Bang
    • Journal of the Society of Naval Architects of Korea
    • /
    • v.38 no.1
    • /
    • pp.99-107
    • /
    • 2001
  • Manufacture of fishing vessel is needed the effective material for light, strength, fire and corrosion of water in order to improve durability by high-speed and fishing. These fishing vessel can be divided into FRP and AI alloys fishing vessel. FRP fishing vessel is light and effective for strength but highly ignited and susceptible to heat during the manufacturing ship by-produce noxious component for human. In the case of a scrapped ship, it cause environmental pollution. On the other hand, aluminum is a material in return for FRP and has merit of high-strength and lightness. It's more heat proof and durable than FRP and superior to prevent from corrosion. Al alloys fishing vessel development is rising as an urgent matter. But, al alloy has some defect of bad weldability, welding transformation, cracks and overcost of construction. Therefore this study is to develop the new welding joint shape solving aluminum defects and mechanical behavior. First of all, strength was compared and reviewed by analysis of plate, stiffen plate, new model simplified by using plate theory. On the base of this result, plate and new model of temperature distribution, weld residual stress and strength of tensile, compressive force were compared and reviewed by finite element computer program has been developed to deal with heat conduction and thermal elasto plastic problem. Also, new model is proved application possibility and excellent mechanic by strength comparison is established to tensile testing result.

  • PDF

Development of Real-time Monitoring Device ($\textrm{JELLI}^{TM}$ chip) for Phase Inversion of Emulsions Under Shear Flow (전단응력 하에서 에멀젼 상 변이의 실시간 측정을 위한 전기 유변학적 연구)

  • 백승재;이영진;남윤정;김진한;김한곤;강학희
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.30 no.1
    • /
    • pp.59-62
    • /
    • 2004
  • To know what happens to the internal structure of emulsions under high shear flow is very important for cosmetic product development because it is highly relevant to the physical degradation of emulsions during the application upon the skin. Here, in order to investigate the response of emulsions against the external shear forces, we designed a new device, .JELLI$^{TM}$ (Joint Electro-rheometer for Liquid-Liquid Inversion) chip, for the measurement of electrical and rheological properties of emulsions under shear flow. By using this device, we examined the real-time changes in conductivities of oil-in-water (O/W) and water-in-oil (W/O) emulsions on the artificial skin during large deformation under shear flow. In this study, O/W and W/O emulsions having various volumes were prepared. After emulsions were homogeneously applied on the artificial skin, the electrical resistance and viscosity changes were monitored under steady shear flow. In case of O/W emulsions, the resistance increased as a function of time. The resistance showed more dramatic increase as the increase of the internal oil phase. It was also found that the viscosity change was proportional to the resistance variation. This phenomenon might be caused by decreased resisting forces against the shear flow because of the breakdown of the internal phase.the internal phase.