• Clinical Pain
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• 제20권2호
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• pp.131-134
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• 2021

We report a rare case of anti-viral agent induced hypophosphatemic osteomalacia presented with localized and radicular pain. A 51-year-old man, who had been taking adefovir for chronic hepatitis, had experienced low back pain radiating to his right thigh for 2 years. With impression of lumbar disc herniation, he underwent magnetic resonance imaging and found multi-level disc herniation with facet joint synovial cysts. He received transforaminal epidural steroid injections, however, symptoms did not improve. To find other possible causes, additional tests were performed. Blood tests revealed hypophosphatemia and increased serum alkaline phosphatase, and osteoporosis was noted in dual-energy X-ray absorptiometry with multiple hot uptakes in bone scan. After replacement of adefovir to entecavir and supplement of phosphate and vitamin D, phosphate level and the clinical symptoms were improved. This is the first to report the presentation of osteomalacia due to anti-viral agent as radicular low back pain with facet synovial cysts.

• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2003년도 식물바이오벤처 페스티발
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• pp.39-48
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• 2003

The ornamental industry encompasses cut flower, pot plant, turfgrass and nursery stock production and is an important part of the agricultural sector. As internationally traded commodities, cut flowers and plants are an integral part of the economy of a number of developing countries in South America, the Caribbean and Africa. Genetic modification (GM) is a tool with great potential to the ornamental horticulture industry. The rapid progress in our knowledge of plant molecular biology can accelerate the breeding ornamental plants using recombinant DNA technology techniques. Not only is there the possibility of creating new, novel products the driver of the industry but also the potential to develop varieties requiring less chemical and energy inputs. As an important non-food agricultural sector the use of genetically modified (GM) ornamental crops may also be ideal for the intensive farming necessary to generate pharmaceuticals and other useful products in GM plants. To date, there are only a few ornamental GM products in development and only one, a carnation genetically modified for flower colour, in the marketplace. International Flower Developments, a joint venture between Florigene Ltd. in Australia and Suntory Ltd.of Japan, developed the GM carnations. These flowers are currently on sale in USA, Japan and Australia. The research, development and commercialisation of these products are summarised. The long term prospects for ornamental GM products, like food crops, will be determined by the regulatory environment, and the acceptance of GM products in the marketplace. These critical factors will be analysed in the context of the current legislative environment, and likely public and industry opinion towards ornamental genetically modified organisms (GMO's).

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2023년도 봄 학술논문 발표대회
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• pp.175-176
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• 2023

The masonry structure is constructed by cement mortar binding material of brick objects and uses reinforced hardware(connected hardware or wall tie) together when building. However, over time, the corrosion of reinforced steel and the deterioration of joint mortar as well as bricks cause the risk of collapse. In particular, when the externally decorated brick wall is installed on the concrete girder for each floor, the angle bracket is not constructed or corroded, the full-layer weight load is applied to the wall of 0.5B, which is an example of full-scale or collapse. As a result of the evaluation, it was confirmed that the performance was improved compared to the existing bracket, and we plan to carry out a real-life test and long-term performance review of the building using the bracket in the future.

• 접착 및 계면
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• 제23권4호
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• pp.101-107
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• 2022

Adhesive joints have many advantages such as weight savings, corrosion and fatigue resistance and now developed even withstand of high impact and dynamic loads. However, an adhesion has cumbersome and complicated surface preparation processes. The surface preparation step is critical in adhesive joint manufacturing in order to obtain the prescribed strength for adhesive joints. In this study, it was attempted to simplify and reduce the number of surface preparation steps, and abrasion and rapid adhesive application (ARAA) process is developed for an alternative solution. The abrasion processes are performed only for creating surface roughness in standard procedures (SP), although the abrasion processes cause surface activation itself. The results showed that there is no need the long procedures in laboratory or chemical agents for adhesion. After the abrasion process, the attracted and highly reactive fresh surface layer obtained, and its effect on bonding success is observed and analyzed in this research, in light of the essential physic and adhesion theories. Al 6061 aluminum adherends and epoxy-based adhesives were chosen for bonding processes, which is mostly used in light vehicle parts. The adherends were cleaned, treated and activated only with abrasion, and after the adhesive application the specimens were tested under quasi-static loading. The satisfied ARAA results were compared with that of the specimens fabricated by the standard procedure (SP) of adhesion processes of high impact loads.

• 대한의용생체공학회:의공학회지
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• 제45권2호
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• pp.75-80
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• 2024

This research investigates the influence of chair tilt functionality on biometric signals and user comfort, addressing the ergonomic challenges posed by modern sedentary lifestyles. Through an experimental study involving eight male participants, the impact of chair tilt on electromyography (EMG), heart rate, metabolic rate, pressure distribution, and distance between the lumbar spine and the lumbar support part of the chair was measured across different seating postures. The study utilized chairs with both synchronous and non-synchronous tilt mechanisms to explore how adjustments in chair design affect user comfort and physiological responses during prolonged sitting. Key findings suggest that chair tilt functionality can significantly reduce muscle activity and energy expenditure, enhancing user comfort and potentially mitigating health risks associated with prolonged sedentary behavior. Notably, the study revealed a preference among participants for chairs that aligned the rotational center of the tilt with the hip joint, highlighting the importance of this ergonomic feature in enhancing user comfort. Additionally, the research proposes a novel methodology for assessing seating comfort through the analysis of both biometric and physical signals, providing valuable insights for the development of ergonomic chair designs focused on user health and comfort.

• 대한정형외과학회지
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• 제56권1호
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• pp.51-60
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• 2021

목적: 요수근 관절 탈구는 고에너지 손상에 의해 발생하며 요골 경상돌기 골절 및 단요월상인대 손상을 동반한다. 단요월상인대는 요골 부착부에서 파열되기도 하지만 요골 월상골와의 전방연에서 견열 골편을 동반하여 발생하기도 한다. 이 연구의 목적은 요골 경상돌기 골절이 동반된 요수근 관절 탈구에서 단요월상인대의 손상 형태 및 치료 방법에 따라 결과의 차이가 있는지 알아보고자 한다. 대상 및 방법: 요수근 관절 탈구로 수술을 시행한 18명을 대상으로 하였다. 요수근 관절 탈구는 Dumontier 등의 방법을 이용하여 Group 1 (순순한 탈구 또는 요골의 작은 견열 골절)과 Group 2 (주상골와의 1/3 이상을 침범한 요골 경상돌기 골절)로 분류하였다. Group 2는 단요월상인대의 부착부가 파열되거나 작은 견열 골절을 동반한 경우를 2A, 비교적 큰 견열 골절을 동반하여 내고정이 가능한 경우를 2B로 분류하였다. 전자는 단요월상인대의 직접 봉합으로, 후자는 작은 나사를 이용한 견열 골편의 내고정으로 치료하였다. 최종 추시에서 통증, 관절 운동 범위와 파악력, 영상 검사를 확인하였다. 치료 결과는 patient-rated wrist evaluation(PRWE), modified Mayo wrist score (MMWS)를 이용하여 평가하였다. 결과: 모든 증례는 Group 2 (2A 6명, 2B 12명)로 분류되었다. 굴신 운동 범위는 건측의 79%, 파악력은 72.9%를 보였다. Group 2A가 2B보다 신전/굴곡/회전에서 더 큰 운동 범위를 보였다. 요사위/척사위/회외전과 통증, 파악력 회복은 차이는 없었다. PRWE, MMWS에서는 두 군의 차이가 없었다. 합병증으로 외상성 관절염 7예, 관절 불안정 5예가 있었다. 결론: 단요월상인대가 손상될 때 요골 월상골와의 전방연에서 발생한 견열 골절은 치료 결과에 영향이 없었다. 그러나 견열 골편이 전위되거나 회전되어 탈구의 정복을 방해하기 때문에 주의해야 하며, 골편에 부착하는 단요월상인대의 기능을 복원하기 위해 해부학적 정복과 견고한 내고정이 필요하다.

• 대한기계학회논문집A
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• 제39권1호
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• pp.27-35
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• 2015

본 연구에서는 피로 하중 및 크리프 하중을 받는 Mod.9Cr-1Mo (ASME Grade 91)강 시편에 대한 일련의 실험결과로부터 재료물성치인 고온 균열진전 모델을 개발하였다. 이 균열진전 모델은 크리프-피로하중을 받는 균열체의 결함평가에 사용되는 물성치이다. 한국원자력연구원이 수행한 일련의 피로 균열진전(FCG) 속도 실험 및 크리프 균열진전(CCG) 속도 실험 결과로부터 균열진전 모델을 결정하고, 이를 프랑스의 고온 설계 기술기준인 RCC-MRx 와 비교함으로써 설계 물성치의 보수성에 대해 검토하였다. RCC-MRx 는 FCG 모델 및 CCG 모델을 Section III Tome 6 에서 제공하고 있는데, 실험으로부터 결정한 균열진전 모델과 비교한 결과 RCC-MRx 의 FCG 모델은 보수적인 것으로 나타난 반면 CCG 모델은 비보수적인 것으로 나타나 동 물성치에 대한 검증이 필요한 것으로 나타났다. 또한 본 연구에서는 기계적 강도 및 크리프 시험결과에 대해서도 RCC-MRx 의 물성치와 비교 및 분석하였다.

• 대한족부족관절학회지
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• 제16권2호
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• pp.94-100
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• 2012

Purpose: The purpose of this study is to analyze the clinical features of distal tibia fractures and to evaluate the treatment outcomes of minimally invasive plate osteosynthesis (MIPO). Materials and Methods: From January 2004 to December 2009, 84 cases of 81 patients treated with plate fixation for distal tibia fracture were enrolled in this retrospective review. We investigated age, sex, injury mechanism, fracture patterns, and complications, and the clinical features were analyzed. To evaluate the treatment outcomes of MIPO, we divided into two groups. MIPO group consisted of 55 patients were treated with MIPO technique and conventional group consisted of 18 patients were treated with open reduction and internal fixation with conventional anterolateral plating. The results were compared between two groups by assessing bony union time, operation time, amount of blood loss, range of ankle motion, clinical score by American Orthopaedic Foot and Ankle Society (AOFAS) score, and post-operative complications. Results: The mean age of 81 patients with distal tibia fracture was 54.8 years. According to AO classification, A1:2:3 were 16, 20, 16 patients, B1:2:3 were 2, 8, 7, C1:2:3 were 1, 3, 11 patients. According to injury mechanism, slip down injury was patients, traffic accident was 26, fall from height injury was 14 patients respectively. The type A fractures were lower energy trauma and more older patients. The type C fractures were higher energy trauma and younger patients. MIPO group was better than conventional group in operative time, blood loss, bony union time, and ankle joint motion. In complications, MIPO group showed no nonunion and infection, one malunion, one skin necrosis, nine skin irritations, and one screw breakage. Conventional group showed two nonunion, four infections, two skin necrosis, and one metal failure. Conclusion: Distal tibial fractures caused by low energy trauma were on the increase. Minimal invasive plate osteosynthesis was shorter bony union time and operation time, less blood loss, and larger ankle motions than conventional open reduction and plate fixation.

• Composites Research
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• 제16권5호
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• pp.45-53
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• 2003

본 논문에서는 이차 본딩으로 접착된 복합재료-복합재료 Single-Lap 조인트 시편에 대해 인장 시험 및 수치해석을 통해 그 파손 특성을 조사하였다. 시편시험에서는 시험 중에 CCD 카메라 및 AE 센서를 이용해 초기 균열의 발생 및 진전양상에 대한 시험적인 관찰을 수행하였다. 시편에 대해 기하비선형 유한요소해석 및 VCCT(Virtual Crack Closure Technique)기법을 이용해 시편의 거동 및 변형율에너지방출률을 계산하고 세 가지 관찰된 초기 균열 모드에 대해 파손강도를 계산하였다. 인장시험에서 초기 균열은 모서리 계면 균열, 측면 계면 균열 및 층간 분리 균열의 세 가지 형태로 최종 파손의 60∼90% 하중에서 발생하였다. 주된 파손 모드는 접착제 계면 파손(adhesive failure) 및 적층판의 첫 번째 및 두 번째의 층간 분리 파손이었다. 두꺼운 접착제 층을 갖는 시편들은 초기균열이 낮은 하중에서 발생하였지만 균열진전에 대한 저항성 및 파손하중은 높게 나타났다. 층간분리파손은 주로 두꺼운 접착제의 경우에 발생하였다. 세 가지 초기 균열 모드에 대해 변형률에너지방출률은 Mode I의 G값이 Mode II의 G값보다 크게 계산되었다. Mode I 및 전체 G값은 측면 계면 균열, 모서리 계면 균열, 층간분리 균열의 순서로 크게 계산되었다.

• 에너지공학
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• 제21권3호
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• pp.249-253
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• 2012

본 연구에서는 열충격 시험을 통하여 Cell 레벨에서의 효율저하 특성을 분석하였다. 열충격 시험은 PV모듈의 시험 규격인 KS C IEC-61215를 이용하여 보다 가혹한 조건인 $-40^{\circ}C$에서 $120^{\circ}C$의 조건으로 500사이클을 수행하였다. I-V 측정을 통하여 효율을 분석한 결과, 열충격 시험 전 13.9%에서 열충격 시험 후 11.0%로 효율이 저하 됐으며, 감소율은 20.9%로 나타났다. EL촬영을 통해 표면을 분석한 결과 Ribbon접합부 및 Gridfinger의 손상으로 확인 됐으며, 보다 정확한 효율 저하의 원인을 분석하기 위해 단면분석을 실시한 결과, 표면손상으로 확인 되었던 위치의 Cell 내부에서도 Crack을 확인할 수 있었다. 또한, FF(Fill Factor)값을 분석한 결과 열충격 시험 전 72.3%에서 시험 후 62.0%로 11.8%의 감소율을 보였다. 따라서, 경년 시 나타나는 효율저하는 I-V 특성 곡선의 변화에 따라 병렬저항($R_{SH}$)이 감소하여 Cell자체의 소모전력 증가 및 표면 손상, Cell 내부의 Crack에 기인하여 가속된다고 판단된다.