• Journal of Interdisciplinary Genomics
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• 제2권2호
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• pp.20-25
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• 2020

Mucopolysaccharidosis type III (MPS III or Sanfilippo syndrome) is a multisystem lysosomal storage disease that is inherited in an autosomal recessive manner. It consists of four subtypes (MPS IIIA, B, C, and D), each characterized by the deficiency of different enzymes that catalyze the metabolism of the glycosaminoglycan heparan sulfate at the lysosomal level. The typical clinical manifestation of MPS III includes progressive central nervous system (CNS) degeneration with accompanying systemic manifestations. Disease onset is typically before the age of ten years and death usually occurs in the second or third decade due to neurological regression or respiratory tract infections. However, there is currently no treatment for CNS symptoms in patients with MPS III. Invasive and non-invasive techniques that allow drugs to pass through the blood brain barrier and reach the CNS are being tested and have proven effective. In addition, the application of genistein treatment as a substrate reduction therapy is in progress.

• Journal of international Conference on Electrical Machines and Systems
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• 제3권4호
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• pp.415-421
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• 2014

In this paper, reactorless high efficiency boost DC/DC converter for EV is proposed. In proposed converter, improves efficiency because decrease power loss when the switches are turned on/off using zero current switching (ZCS) at all switch of primary full bridge. By replacing reactance ingredients of L-C resonance circuit for ZCS with leakage inductance ingredients of high frequency transformer, it reduces system size and expense because of not add special reactor. For validity verification of proposed converter, in the paper implements simulation using PSIM and perform experiment by making 5KW DC/DC converter. In experimental results, efficiency of proposed converter conformed superiority.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2012년도 추계학술대회 논문집
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• pp.237-238
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• 2012

본 연구는 태양전지용 실리콘 결정 성장용으로 개발된 150[KW] 3,000[A]의 PWM 컨버터 시스템을 개발한 결과이다. 시스템의 구성은 3상 AC-DC 정류변환기, DC-AC 고주파 변환 단상 전파 브리지 PWM 인버터, AC-DC 변압기 중성점을 이용한 단상 전파정류기로 구성되어 있다. 입력 전압은 3상 460[V]이며, 출력은 직류 60[V], 3000[A]로 카본 저항 $2[m{\Omega}]$의 부하에 인버터의 고주파 변압기를 사용하여 스위칭 주파수가 15[KHz]로 PWM제어 방식에 의하여 전력을 제어한다.

• 한국기계가공학회지
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• 제14권1호
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• pp.15-20
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• 2015

I developed a high-quality metal door with a hologram-pattern design using a high-speed electroforming process. In this study, the major processes were master production, conducting grant, nickel-sulfamate acid electroforming, ablation treatment, and final dressing. The processing system was provided with a nickel sulfamate pole, and a rotary-pole PP-plating jig in a circular tank. This approach could reduce defects and errors, as much as possible, by its use of a hologram pattern to create the master of a metal door. The thin-sheet metal-creation process for the door built-in metal pattern using electroforming with hologram was successful.

• 한국정보통신설비학회:학술대회논문집
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• 한국정보통신설비학회 2003년도 하계학술대회
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• pp.373-375
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• 2003

통신사업자들은 다양한 정보서비스를 제공하기 위한 노력과 통신품질 향상을 위한 시도를 다양하게 진행하고 있으며, 우수한 품질의 서비스를 저렴하게 공급하기 위한 노력도 시도하고 있다. 본 고에서는 KT가 경영 합리화와 내부 원가절감을 위한 여러 가지 노력 중에서 투자시설 공사와 관련하여 공사원가 계산방법의 개선을 위해 새로 도입한 다양한 방법들을 살펴본다. 특히 교환시설분야에서 적용 중인 실적공사비에 의한 예정가격 산정방법을 중심으로 개념과 적용사례 분석을 하기로 한다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1992년도 추계학술대회 논문집
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• pp.249-254
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• 1992

Hydrostatic Bearings have been applied to ultra high precision machine tools and precision instruments, because of their low friction characteristic, high load carrying capacity and high moving accuracy at all range of speed. In regard to realizing the Hydrostatic Bearing, various restrictors such as capillary, orifice, diaphram valve, spool valve, and etc can be used. However, their stiffness and flexibility are not sufficient in practical use for ultra precision machine tool elements. In this study dynamic equations were derived and the dynamic characteristics were simulated for both orifice and flow control servo valve. Simulation was carried out on the condition that static and sinusoidal dynamic loads were applied to the table of CNC jig Boring machine. The simulation results indicate the improvement of the performance of the Bearing system when flow control servo valve has been used as restrictor of Hydrostatic Bearing.

• 산업경영시스템학회지
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• 제25권3호
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• pp.41-49
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• 2002

In the study, for the practical approaches of job shop scheduling, we propose the new dispatching rules of job shop scheduling in order to complement the practical applications in the existing researches. The assumed situation for the practical approaches considers the following; relaxation of assumption for capacity constraint by machine flexibility, the addition of the common use of jig and fixture, unbalanced machine workloads and duedate tightness, and produces fast rescheduling that reflects unexpected situations. The performance of the new dispatching rules is compared and analyzed with the existing methods through the computer experiments in the assumed conditions. The results can be useful to improving a field application of the job shop scheduling.

• 산업경영시스템학회지
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• 제24권68호
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• pp.37-50
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• 2001

Although the study of OCB has increased greatly in recent years, a little works have focused on the relationship between leadership and extrarole behavior, and the moderating effects of the situational factors on the relationship between two factors. For the analytical purpose of this article, Fisher＇s Z-transformation and SGC(split groups correlations) methods were introduced. Generally 2 leadership styles are found to have influenced on altruism and conscientiousness respectively. Out of 36 cases, only 2 cases were significant in moderating effects. Based on empirical results, there is no moderating effects in conscientiousness. But altruism is found to be more closely related with employee-centered leadership in low centralized group than in high centralized group, and more closely related with job-centered leadership in low growth-needs group than in high growth-needs group.

• 한국조명전기설비학회:학술대회논문집
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• 한국조명전기설비학회 2005년도 학술대회 논문집
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• pp.289-291
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• 2005

본 연구는 페러데이 효과(Faraday Effect)를 이용한 GIS용 광 CT의 개발을 위하여 출력신호의 정밀성과 안정성 향상을 위한 신호분석 시스템에 대해 검토하였다. 기존 광 CT의 Verdet 상수 의존도와 온도에 따른 특성 및 노이즈에 대한 정밀성을 개선하기 위해 신호처리 시스템 이용하여 신호를 균일화시키고 온도 보상 프로그래밍을 이용하여 온도 특성에 따른 오차를 저감시키고자 한다. 또한 신호 계측부와 신호 처리부를 분리하여 신호 처리부를 프로그래밍 시켜 실시간으로 광 CT 특성을 모니터링 할 수 있는 시스템을 연구 검토하였다.

• 한국정밀공학회지
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• 제13권5호
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• pp.60-66
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• 1996

Precision of bearing race is very important to maintain the clearance between ball and inner race. In internal grinding of bearing race, its roundness is dependent on shoe wear, accuracy of jig, dressing method and grinding conditions. In this study, the characteristics of shoe wear and eccentricity of workpiece were investigated experimentally. When wear of fornt shoe wear reaches at 100.mu. m and that of rear shoe reaches at 114 .mu. m, eccentricity of inner race is increased to 1.4 .mu. m. Roundness of race is mainly related to wear of rear shoe and ring type shoe is recommended to improve roundness of race.