• Title/Summary/Keyword: Ji-san

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Acute Toxicity Study on Insampaedok-san and Fermented Insampaedok-san (인삼패독산(人蔘敗毒散) 및 발효인삼패독산의 급성독성 연구)

  • Im, Ga-Young;Hwang, Yoon-Hwan;Lee, Ji-Hye;Oh, You-Chang;Cho, Won-Kyung;Ma, Jin-Yeul
    • Journal of Society of Preventive Korean Medicine
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    • v.15 no.3
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    • pp.141-152
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    • 2011
  • Objective : This study was carried out to investigate the acute toxicity and safety of Insampaedok-san and Fermented Insampaedok-san. Methods : SPF ICR male and female mice were administered orally with Insampaedok-san and Fermented Insampaedok-san. of 0(control group), 1,250, 2,500 and 5,000 mg/kg. After single administration, we daily examined number of deaths, clinical signs, gross findings and changes of body weight for 14 days. Hematological parameters and isolated organ weights were determined after 14 days of administration. Results : No dead animal and no significant changes of body weights were found during experimental period. In addition, no differences were found between control and all of treated groups in clinical signs, organ weights, hematology, and other findings. Conclusions : Insampaedok-san and Fermented Insampaedok-san. did not show any toxic effects and oral $LD_{50}$ values of the extracts was over 5,000 mg/kg in ICR mice.

Ahn Ji-Jae's 《Xiang Ming Suan Fa》 (안지재의 《상명산법》)

  • Lee, Kyung Eon
    • The Mathematical Education
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    • v.53 no.1
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    • pp.111-129
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    • 2014
  • ${\ll}$Xiang Ming Suan Fa${\gg}$ written by Ahn Ji-Jae, a scholar of Yuan Dynasty, is a very important mathematics text in development of mathematics in Joseon Dynasty. Also, ${\ll}$Xiang Ming Suan Fa${\gg}$ in possession of Keimeung university was designated as a Korean National Treasure on February 25, 2011. In this paper, we analyzed the structure and contents of ${\ll}$Xiang Ming Suan Fa${\gg}$. Also, we studied the influences of ${\ll}$Xiang Ming Suan Fa${\gg}$ on Joseon Dynasty's mathematics according to the comparing with mathematics books such as ${\ll}$Mook Sa Jib San Bub> and ${\ll}$San Hak Yib Moon${\gg}$.

The Bibliogrphical Study on the Allergic Rhinitis (알레르기性 鼻炎에 對한 文獻的 考察)

  • Kim, Hyun-Ah;Jung, Ji-Chun
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.7 no.1
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    • pp.53-84
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    • 1994
  • The study has been carried out to investigate of the Allergic Rhinitis by referring to 87 literatures. The results were as follows; 1. In oriental medical science, Allergic Rhinitis is belong to the category of the 'BiGu'(鼻구) 'GuChe'(구체). The 'Gu'(구) of the BiGu means watery rhinorrhea, the 'Che'(체) of the GuChe means sneezing. 2. The cause of a disease summarize the weak of Lung, Spleen and Kidney, and invasion into the nasal cavity of PoongHan etc a wrong air. Sometimes the pathologial change appear PoongHan changeHwa(風寒化火), HwaYeol is hidden in the inside(火熱內伏). The contributing factors are found a season(spring, winter), an abnormal weather(運氣 : 少陰 少陽 陽明 司天, 歲金不及), an emotional stress, an external wound of the harmful air, a food allergens and fatigue, a contact of substances, a sunlight etc. 3. Predominant symptoms are watery rhinorrhea, sneezing and nasal obstruction. Sometimes accompanic symptoms are nasal bleeding, mucopurulent rhinorrhea, olfactory disturbance, nasal polyp, rhinolalia clausa, respiratory disfunction etc. 4. The treatment-methodes is as follows, OnBoPaeJang GeoPoongSanHan(溫補肺臟 祛風散寒), GeonBilkGi(健脾益氣), BoSinNabGi (補腎納氣). The treatmentherbs is as follows, OnBoJiLuDan GaGam(溫補止流丹 加減), OkByeongPoongSan plus ChangIJaSan GaGam(玉屛風散合 蒼耳子散 加減), BoJungIkGiTang GaGam plus SoCheongLyongTang(補中益氣湯加減 配合 小靑龍湯), SinGiHwan GaGam(腎氣丸加減), GaeJiTang(桂枝湯) etc. 5. The external treatment is as follows, JeokBi(滴鼻), ChuiBi(吹鼻), SaekBi(塞鼻), stick and herbs-injection on the acupuncture-point, pressure ear acupuncture-point, herbs-pillow etc. 6. The acupuncture-moxa treatment is as follows, the methodes of cure apply TongJoGyeongGi(通調經氣), SanTongBiGui(宣通鼻竅) etc. Predominent acupuncture-points are YoungHyang(迎香), InDang(印堂), BiTong(鼻通), SangSeong(上星), HabGok(合谷) and so on. As mentioned above, from now on, it's need to the oriental medical scientific study of the Immunity and Allergy and to the external treatment's application for the ascent of the treatment-effect of the allergic disease.

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Case Report: Korean Medicine Treatment for Diabetic Peripheral Neuropathy Concurrent with Chemotherapy-Induced Peripheral Neuropathy (당뇨병성 말초신경병증에 병발한 항암화학요법 유발 신경병증의 침구치료 1례)

  • Ji-yoon Park;Ye-seul Kim;Jung-hwa Hong;Young-ju Rhee;Eun-joo Seok;Lib Ahn
    • The Journal of Internal Korean Medicine
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    • v.44 no.2
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    • pp.222-230
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    • 2023
  • Objectives: This study reports the effectiveness of acupuncture and moxibustion for Diabetic Peripheral Neuropathy concurrent with Chemotherapy-Induced Peripheral Neuropathy. Case presentation: A 58-year-old male was admitted for hand numbness and foot pain after his sixth chemotherapy. He was treated with acupuncture and moxibustion for 18 days. Symptoms were evaluated with a numeric rating scale (NRS). After 18 days of treatment, his foot pain improved from NRS 4 to NRS 2. His hand numbness disappeared. Conclusion: This study suggests that acupuncture and moxibustion can be used for managing diabetic peripheral neuropathy concurrent with chemotherapy-induced peripheral neuropathy.

The Abstraction of Cultural Videos Using Similarity Measures (유사성 측정을 이용한 교양비디오의 개요 추출)

  • Lee, Ji-Hyun;Mun, Jong-Hwan;Jin, Song-Cheol;Rhee, Yang-Won
    • Proceedings of the Korea Information Processing Society Conference
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    • 2004.05a
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    • pp.169-172
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    • 2004
  • 키 프레임들의 컬러 정보 차이 값과 표준편차 차이 값을 이용한 유사성측정 방법을 기반으로 클러스터링을 이용하여 의미 있는 단위로 분할되어 색인화 된 비디오에서 중요 장면들을 추출하고 추출된 키프레임들을 대상으로 중간(middle)샷 개요 생성 규칙을 적용하여 요약된 형태의 비디오 개요를 추출하여 사용자들에게 제공함으로써 비디오 선택의 폭을 넓힐 수 있도록 제안하였다.

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The Scene Change Detection of Cultural Videos Using Hybrid Detecting Techniques (하이브리드 검출기법을 이용한 교양비디오의 장면 전환 검출)

  • Lee, Ji-Hyun;Jin, Song-Cheol;Mun, Jong-Hwan;Rhee, Yang-Won
    • Proceedings of the Korea Information Processing Society Conference
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    • 2004.05a
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    • pp.165-168
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    • 2004
  • 기존 장면 전환 검출 방법들은 대부분 특정 영역에 제한되어 사용할 수 있는 방법들이며, 많은 중요한 특징 정보들을 유실하여 장면 전환 검출에 효율적이지 못하였다. 또한 장면 전환 검출을 통하여 의미 정보를 추출하기가 어렵고, 카메라와 객체의 동작을 정확히 인식하지 못하기 때문에 하이브리드 장면전환 검출 기법을 적용하여 의미 있는 정보를 효율적으로 검출 하였다.

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Anti-inflammatory Effects of Ojeok-san in LPS-induced Inflammatory Rat Model (LPS유도 염증 동물모델에서 오적산의 항염증 효과)

  • Kim, Joo-Hee;Lee, Dong Hyuk;Kim, Ji Hye;Jung, Sung Eun;Ham, Seong Ho;Yang, Woong Mo;Kwon, Bo-in
    • The Journal of Korean Medicine
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    • v.42 no.2
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    • pp.21-30
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    • 2021
  • Objectives: The aim of this study is to investigate the anti-inflammatory effects of Ojeok-san and compare the therapeutic effects according to its formation. Methods: We evaluated the anti-inflammatory effects of Ojeok-san using lipopolysaccharide (LPS) induced inflammatory animal model. Male SD rats were administered intra-orally with two different formulation types of Ojeok-san according to prescribed dosage. One hour later, to induce inflammatory responses, subsequent intra-peritoneal injection of LPS was conducted. After 5 hours later, serum TNF-α, IL-1β, IL-6 and PGE2 levels were measured by ELISA to assess the alteration of pro-inflammatory markers. Results: In our experiment, regardless of its formation, administration of Ojeok-san decreased TNF-𝛼, IL-1𝛽, IL-6 and PGE2 level in serum. Furthermore, LPS-induced toxicity of liver and kidney was not detected by Ojeok-san administration. Conclusions: The anti-inflammatory effect of Ojeok-san was shown in LPS-induced inflammatory model by decreasing pro-inflammatory markers, and there would be no significant difference in therapeutic effect between two formulation types of Ojeok-san.

Adverse Event Study on Ojeok-san Extract Powders RCT in Low Back Pain Patients (요통환자 대상 오적산 엑스산 투여 임상시험 이상반응 연구)

  • Yoon, Eun-Hye;Jang, Min-Gee;Hwang, Ji-Hoo;Lee, Seung-Hoon;Jeong, Won-Je;Lee, Jae-Dong;Lee, Seung-Deok;Kim, Kyung-Ho;Kim, Kap-Sung;Kim, Eun-Jung
    • Journal of Acupuncture Research
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    • v.27 no.4
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    • pp.195-202
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    • 2010
  • Objectives : This study was performed to report adverse events in Ojeok-san extract powders RCT. Methods : 180 patients with LBP were randomized into groups for a double blind, placebo-controlled clinical study. They received Ojeok-san simple Extract, Ojeok-san complex Extract or placebo in powders, orally dissolved 3times a day for 4weeks. During 4weeks, we researched the symptoms and duration of adverse events and Digest ability, Milk hypersensitivity, Starch hypersensitivity, Caramel hypersensitivity, West-med hypersensitivity, Herb-med hypersensitivity in patients who had adverse events. Results : 52patients(28.9%) had adverse events and of them 44patients(28.9%) had lost adverse events naturally. But 5patients(2.8%) were withdrawn from the research because of the adverse events. Most of the symptoms of adverse event was Gastrointestinal symptom(88.3%) and adverse events frequency was not different from Ojeok-san simple Extract, Ojeok-san complex Extract and placebo. Conclusions : Ojeok-san extract powders had adverse events no different from the placebo, which shows that it is a safe drug.