• Journal of Embryo Transfer
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• v.31 no.1
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• pp.9-12
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• 2016

Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are oocyte-specific growth factors that regulate many critical processes involved in early folliculogenesis and oocyte maturation. In this study, effects of GDF9 and BMP15 treatment during in vitro maturation of porcine oocytes upon development after parthenogenetic activation were investigated. Neither GDF, BMP15 alone nor in combination affects the number and viability of cumulus cells or the rates of oocyte maturation and blastocyst development. However, the treatment of GDF9 on porcine oocytes increased the number of trophectodermal (TE) cells of blastocysts derived from activated oocytes (P<0.05). The treatment of BMP15 increased the cell numbers of both inner cell mass (ICM) and TE cells (P<0.05). The treatment with the combination of GDF9 and BMP15 further increased the numbers of ICM and TE cells, compared with GDF9 or BMP15 treatment alone (P<0.05). In conclusion, the treatment of GDF9 or BMP15 (or both) enhanced the quality of blastocysts via the increased number of ICM and/or TE cells.

• Journal of the Korean Society of Propulsion Engineers
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• v.12 no.2
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• pp.24-32
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• 2008

A non-reacting experimental study on a normal injection into a Mach 1.92 crossflow which flows over various geometries(flat plate, small cavity, large cavity) was carried out to investigate the effect of the momentum flux ratio(J). The aft ramp of the cavity advances the increase of the penetration height and the strong two-dimensional shock from recompression region mainly affects the shock structure and mixing layer at the downstream flow. As flow runs downward, the transverse penetration height increases with increasing J(J = 0.9, 1.7, 3.4). However, above some critical ratio, jet penetration height growth with increasing J is not appeared in flow-field. Large scale cavity has a good mixing efficiency but it increases the drag loss in the combustor.

• 한국연소학회:학술대회논문집
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• 2014.11a
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• pp.133-134
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• 2014

The full transport equation approach for laminar non-premixed flame with detailed chemistry, soot and radiation has an advantage in accuracy and describing for emission pathway, but this approach requires the excessive computational cost especially for a higher-order hydrocarbon fuel flames. On the other hand, the standard flamelet model has an efficiency and accuracy for non-premixed flame, though this model is not suitable for simulating slow processor like soot and radiation in laminar non-premixed flame situation. To overcome this limitation, modified transient flamelet model is developed which coupled with two-equation soot model involved in soot formation and evolution mechanism such as nucleation, surface growth, oxidation and agglomeration.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.27 no.2
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• pp.236-242
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• 2003

Thermal bubbles find their diverse application areas in the MEMS (MicroElectroMechanial Systems) technology, including bubble jet printers, microactuators, micropumps, etc.. Especially, microactuators and micropumps, which use a microbubble growing by a controlled heat input, frequently involve mechanical and thermal interaction of the bubble with a solid structure, such as a cantilever beam and a membrane. Although the concept is experimentally verified that an internal pressure of the bubble can build up high enough to deflect a thin solid plate or a beam, the physics of the entire process have not yet been thoroughly explored. This work reports the experimental study of the growth of a thermal bubble while deflecting a thin cantilever beam. A physical model is presented to predict the elastic response of the cantilever beam based on the experimental measurements. The scaling law constructed through this work can provide a design guide for micro- and nano-systems that employ a thermal bubble for their actuation/pumping mechanism.

• Transactions of the Korean Society of Mechanical Engineers
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• v.17 no.12
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• pp.3148-3165
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• 1993

A cascade wind tunnel test for a turbine nozzle, which was designed for a small turbo jet engine in a previous study, has been conducted to evaluate its aerodynamic performance and losses. The large-scale blades were based on the mid-span profile of the nozzle. Oil film flow structure, and then 3-dimensional velocity components were measured in the flow passage with a 5-hold pressure probe, in addition to turbulent intensities at mid-span of cascade exit using a hot-wire anemometer. From this study, 3-dimensional growth of horseshoe and passage vortices in the downstream direction was clearly understood with near-wall flow phenomena. In addition, secondary flow and losses associated with the blade configuration were obtained in detail.

• Journal of ILASS-Korea
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• v.3 no.2
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• pp.34-41
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• 1998

The present experimental study investigates the effect of an initial disturbance on the breakup mechanism of a liquid column. With varying the maginitude of the inital disturbance, we measure the surface wave of liquid column with adopting laser shadow method and analyze the growth rate of liquid column and breakup frequency. The experimental results show that thebreakup characteristics of liquid column is significantly influenced by the frequency of the initial disturbance. We concluded that the most uniform droplet occurs when the frequency of initial disturbance coincides with the natural frequency of the liquid column.

• Journal of Veterinary Clinics
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• v.14 no.1
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• pp.118-122
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• 1997

The lateral hoof of right hind limb of a pregnant Masai giraffe was accidentally injured, and its coronet, hoof wall, and sole were detached in a mass. The bleeding was observed from the exposed dermis of the affected foot for several hours, with second scoreof supporting lameness. The bleeding from the digital artery at the exposed dermis was stopped by epinephrine spray and direct pressing. Nitrofurazone ointment was topocally applied for 5 days and sxytetracycline solusion was delivered by a fluid jet in the affected hoof one month. The calf was born 5 months after the avulsion. The horn of the hoof wall was grown from the coronet to sole, and was gradually filled from the heel to the toe. The growth rate and filling rate of the hoof wall were 0.32mm and 0.54mm a day, respectively.

• Journal of the Korean Society of Visualization
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• v.21 no.2
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• pp.102-110
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• 2023

With the global shift from a carbon-based economy to a hydrogen-based economy, understanding the sloshing phenomenon and its impact on boil-off rate (BOR) in liquid hydrogen (LH2) tank trailers is crucial. Here, we analyze the primary breakup process under sloshing phenomena in a liquid fuel tank. We observe the growth of multiple holes on the sheet-like structures and the formation of ligament structures reminiscent of jet atomization. Through the extraction of three-dimensional liquid regions, we analyze the geometrical characteristics of these regions, enabling the classification of sheets, ligaments, and droplets. The present findings could contribute to understanding the breakup mechanism and hold potential for the development of strategies aimed at minimizing BOR.

• Korean Journal of Agricultural and Forest Meteorology
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• v.12 no.3
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• pp.183-196
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• 2010

Increasing human activity due to rapid economic growth and land use change alters the patterns of the Asian monsoon, which is key to crop yields in Asia. In this study, we tested the performance of regional climate model (RegCM3) by simulating important components of Indian summer monsoon, including land-ocean contrast, low level jet (LLJ), Tibetan high and upper level Easterly Jet. Three contrasting rain years (1994: excess year, 2001: normal year, 2002: deficient year) were selected and RegCM3 was integrated at 60 km horizontal resolution from April 1 to October 1 each year. The simulated fields of circulations and precipitation were validated against the observation from the NCEP/NCAR reanalysis products and Global Precipitation Climatology Centre (GPCC), respectively. The important results of RegCM3 simulations are (a) LLJ was slightly stronger and split into two branches during excess rain year over the Arabian Sea while there was no splitting during normal and deficient rain years, (b) huge anticyclone with single cell was noted during excess rain year while weak and broken into two cells in deficient rain year, (c) the simulated spatial distribution of precipitation was comparable to the corresponding observed precipitation of GPCC over large parts of India, and (d) the sensitivity experiment using NIMBUS-7 SMMR snow data indicated that precipitation was reduced mainly over the northeast and south Peninsular India with the introduction of 0.1 m of snow over the Tibetan region in April.

• Journal of Embryo Transfer
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• v.28 no.2
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• pp.149-155
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• 2013

Mullerian inhibiting substance (MIS) is a member of the TGF-${\beta}$ (transforming growth factor-${\beta}$) family whose members play key roles in development, suppression of tumour growth, and feedback control of the pituitary-gonadal hormone axis. MIS is expressed in a highly tissue-specific manner in which it is restricted to male Sertoli cells and female granulose cells. The serum levels of MIS in prenatal and postnatal ICR mice were measured using the enzyme-linked immuno-solvent assay (ELISA) using the MIS/AMH antibody. Mice were grouped by age: the significant periods were at the onset of development. During sex organ differentiation, no remarkable difference between female and male foetus MIS serum levels (both<0.1 ng/ml) was observed. However, MIS serum levels in pregnant mice markedly changed (4.5~12.2 ng/ml). After birth, postnatal female and male mice serum MIS levels changed considerably (male: <0.1~138.5 ng/ml, female: 5.3~103.4 ng/ml), and the changing phase were diametrically opposed (male: decreasing, female: fluctuating). These findings suggest that MIS may have strong associations with not only develop-ment but also puberty. For further studies, establishing the standard MIS serum levels is of importance. Our study provides the basic information for the study of MIS interactions with reproductive organ disability, cancer, and the effect of other hormone or menopause. We hypothesise that if MIS is regularly injected into middle-age women, meno-pause will be delayed. We detected that serum MIS concentration curves change with age. The changing phase is different between males and females, and this difference is significant after birth. Moreover, MIS mRNA is expressed during the developmental period (prenatal) and also in the postnatal period. This finding indicates that MIS may play a significant role in the developmental stage and in growth after birth.