• The Journal of the Korea Contents Association
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• v.14 no.5
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• pp.251-261
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• 2014

Primary percutaneous coronary intervention (PCI) has been found to be superior, in terms of hospital mortality and long-term outcome, compared with thrombolytic therapy in patients with acute myocardial infarction (AMI). However, the clinical benefits of primary PCI have not been precisely evaluated in elderly patients.1,974 patients (Group I: n=1,018, $age{\geq}65years$, $73.8{\pm}5.99years$; Group II: n=956, age<65years, $52.8{\pm}7.96years$) who underwent primary PCI for AMI at Chonnam National University Hospital between 2006 and 2010 were analyzed according to their clinical, angiographic characteristics for hospital and one-year survival. Group I had a higher percentage of women, diabetes mellitus, hypertension, multi-vessel disease and lower prevalence of current smoking, hyperlipidemia, familial history than Group II. Culprit lesions were at the left anterior descending artery, left circumflex artery, right coronary artery and left main artery in 42.8% vs. 45.0%, 34.1% vs. 29.6%, 14.6% vs 14.6, 2.7% vs. 1.6%, respectively (p=0.007). Stent diameter was smaller in group I ($3.17{\pm}0.39$ vs. $3.29{\pm}0.42mm$, p=0.001). In-hospital mortality was higher in group I (8.4 vs. 1.9%, p<0.001). There were significant differences in the rates of major adverse cardiac events between the two groups during one-year clinical follow-up (20.1 vs.14.0%, p<0.001). On multiple logistic regression analysis, systolic blood pressure<100mmHg, serum $creatinine{\geq}1.3mg/dL$, Killip class> I, multivessel disease, left ventricular ejection fraction <40% and cerebro vascular disease were independent predictors of one-year motality in patients over 65 years after PCI.

• Clinical and Experimental Pediatrics
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• v.50 no.12
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• pp.1217-1224
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• 2007

Purpose : Due to its high potency against leukemic blasts, our institution has opted for the use of dexamethasone during acute lymphoblastic leukemia (ALL) remission induction, but in our most recent treatment protocol, CMCPL-2005, we shortened the length of steroid treatment from 4 to 3 weeks. We compared both the rates of remission induction and significant complications observed during induction with CMCPL-2005, with those noted for our previous protocol, CMCPL-2001. Methods : We retrospectively reviewed the records of patients diagnosed with ALL from January, 2001 to December, 2006 at the Department of Pediatrics, St. Mary's Hospital, the Catholic University of Korea. Data concerning age, sex, WBC count at diagnosis, immunophenotype, cytogenetic traits, and risk group were collected for each patient. Results of remission induction treatment were compared between the two patient groups. Infection and other major complications resulting from treatment were investigated according to NCI toxicity criteria. Results : A total of 141 and 88 patients received remission induction under CMCPL-2001 and CMCPL-2005 respectively. In the CMCPL-2001 group, 136 (96%) achieved complete remission while 82 (93%) achieved CR in the CMCPL-2005 group. Patients in the CMCPL-2005 group were more likely to undergo remission induction without experiencing major complications. However, with regards to steroid related toxicities such as infection, no significant differences were noted. Conclusion : We shortened the length of steroid administration from four to three weeks, yet found the remission induction rate to be comparable to that of our previous regimen. However, rates of steroid related toxicities such as infectious complications remain unchanged despite shortened exposure to dexamethasone.

• Journal of the Korea Organic Resources Recycling Association
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• v.25 no.1
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• pp.67-78
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• 2017

The purpose of this study was to investigate the effect of humic acid on the germination, the growth and the yield of hot pepper when treated with organic hot pepper seedlings and growing season. The germination rate of 0.05% and 0.1% humic acid was higher than that of untreated, but the germination rates of 0.4% and 1.0% humic acid were 90.0% and 86.7%, respectively, compared with the control treatment (96.7%). At 30 days after transplanting, hot pepper treated with low (0.05%) or high (1.0%) concentration of humic acid decreased the growth of hot pepper seedlings, whereas 0.2% humic acid treatment significantly increased a average height (97.6 cm), leaf number (84.7) and fresh weight ($128.1g\;plant^{-1}$) of hot pepper. After 60 days of treatment with humic acid, the height of hot pepper was significantly longer in 0.2% humic acid. The mean green fruit number of 0.2%, 0.1% and 0.05% humic acid were not significantly different among the treatments, but the mean green pepper number of 0.4% and 1.0% humic acid treatments were the higher with 35.2% and 29.1%, respectively than other treatments. However, the fresh weight of green pepper was found to be $111.5g\;plant^{-1}$ more heavier than the untreated in 0.2% humic acid. The total ($5.8kg\;plant^{-1}$) and average ($1.4kg\;plant^{-1}$) fresh weight of pepper were higher than that of untreated control, except for the 1.0% humic acid treatment after 60 days of soil irrigation. The total weight of hot pepper treated with 0.2% and 0.1% humic acid treatment was $9.3kg\;plant^{-1}$ and $8.6kg\;plant^{-1}$, respectively, which were heavier than the other treatments. The effect of humic acid concentrations on soil microbial populations, pH and EC was investigated. The soil bacterial population density of 0.2% humic acid treatment was 3.5 times higher than that of untreated control soil. As the concentration of humic acid increased from 0.05% to 1.0%, pH and EC of hot pepper grown soil also increased.

• Korean Journal of Poultry Science
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• v.40 no.4
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• pp.299-304
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• 2013

Tracheal epithelial cells (TECs) are an important tool for studies of viral respiratory diseases. Primary TECs have been cultured from human, mouse and hamster. It is also necessary to diagnose viral respiratory disease and reveal infection mechanisms in chicken. In this study, we isolated tracheal epithelial layers from tracheal of 20-day-old chicks and cultured primary TECs from the isolated layers. Ciliated cells which were a typical morphology of TECs were observed in cultured primary TECs and maintained until cell passage 5 (15 to 20 days). When we analyzed expression patterns of epithelial marker genes (retinoic acid responder, FGF-binding protein, virus activating protease (VAP) in TECs compared to immortalized chicken embryonic fibroblast cell line (DF-1), all the marker genes are highly expressed in TECs than in DF-1. When TECs were cultured with 0.1 and 1 MOI of ND virus (rNDV-GFP strain) to test the susceptibility of TECs for ND virus, 12.6% and 48.2% of the incubated TECs were infected respectively. In addition, when DF-1 was incubated with 1 MOI of ND virus, the virus infection rate of DF-1 was three times lower than the virus infection rate of TECs. These data could contribute to study infection mechanisms of viral respiratory diseases and control them in chicken.

• Journal of Bio-Environment Control
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• v.13 no.4
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• pp.200-208
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• 2004

Effects of cucumber and tomato seed germination by previous leaf and root vegetables (cabbage, radish, welsh onion, lettuce) residue in soil were tested in pot condition. Overall, suppression effect of welsh onion residue was the greatest in 4 tested crop residue and followed by radish, cabbage and lettuce, but lettuce residue didn't have effect on cucumber seed germination. Suppression were maintained ca. 20 days but after the time point, growth of cucumber and tomato were enhanced. Enhancing effect of welsh onion residue was the greatest in 4 tested crops residues and followed by radish, cabbage and lettuce. As a conclusion, residue of welsh onion, radish and cabbage were suppressed the germination of cucumber and tomato seeds but enhanced growth after 20 days of treatment. To verify the effective concentration of residue on suppression of germination and growth of radicle of cucumber and tomato, plant extract of welsh onion, radish, cabbage and lettuce were diluted as 5, 10, 17, 23, 35, 50, and $65\%$, and then tested. In low concentration treatment, 5, 10, 17, and $23\%$, all 4 crop extracts didn't suppress cucumber seed germination. High concentration of lettuce extract, 35, 50, and $65\%$, cucumber seed didn't germinate at all. In case of welsh onion extract, only $65\%$ treatment suppressed cucumber seed germination. In low concentration treatment, 17, and $23\%$, only the welsh onion extract suppressed young radicle. In case of high concentration treatment, except $35\%$, all four crops extract suppressed cucumber radicle growth. In low concentration treatment, tomato seed germination was suppressed by lettuce extract only but in high concentration treatment, 35, 50, and $65\%$, all extracts suppressed germination. Especially higher than $50\%$ treatment, tomato seed didn't germinate at all. Radicle growth was highly suppressed in welsh onion and lettuce extract, higher than $23\%$ concentration. As conclusion, leaf and root vegetable extracts suppressed cucumber and tomato seed germination and in high concentration, also suppressed radicle growth.

• Journal of Bio-Environment Control
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• v.23 no.3
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• pp.205-211
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• 2014

This study aimed to examine the effect of different fruit-loads on fruit yield, quality, and plant growth of 'Seolhyang' strawberry. Fruit loads were adjusted from the first to the fourth flower cluster so that the number of fruits became 20, 25, and 30, and non-flower thinning of some was made. The more the number of fruits per plant was, the greater the total yield obtained, but marketable yield decreased and non-marketable yield increased. Compared to the treatment whose fruit load was adjusted, the control with non-flower thinning had more fruit yield in the first and second flower clusters but tended to have less fruit yield in the third and fourth flower clusters. The lower the fruit load was, the more soluble solids content of fruits increased. The lower the fruit load of a flower cluster was, the faster its harvest time reached. Harvest of fruit load of 20 was faster by 10 days in the second and fourth flower clusters relative to the control. On November 24, 2012, flowering thinning of the first flower cluster was made. On March 7, 2013, fruit dry weight of the second flower cluster was most heavy in the control. Dry weight of roots decreased in the control and the fruit load of 30 compared to November 24. On April 9, fruit dry weight of the third flower cluster did not have significant difference according to fruit load, however the more the fruit load was, the smaller dry weight of leaf, root, and crown became, which were vegetative organs. On May 12, the more the fruit load, the smaller leaf area and dry weight of vegetative organs and differences from varying fruit-loads became considerable in later period of growth. Appropriate fruit load of 'Seolhyang' strawberry were from 20 to 25. Maintaining balance between vegetative and fruit growth by adjusting fruit load is very important for stable fruit production.

• Journal of Bio-Environment Control
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• v.27 no.1
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• pp.13-19
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• 2018

This study was conducted to examine the germination and growth during seedling period of Codonopsis lanceolata and Astragalus membranaceus as affected by different media. The seeds were sown in commercial medium (Tosilee), coir, rockwool, and urethane sponge. The seeds were germinated for 22 days in a closed-type plant production system, and seedlings were grown for 35 days after sowing in the venlo-type glasshouse located on Gyeongsang National University. Nutrient solution was supplied by the sub-irrigation as EC $1.0dS{\cdot}m^{-1}$ and pH 6.5 every second day. Final germination of Codonopsis lanceolata was the significantly highest in the coir and rockwool media as 68.5% and 67.9%, respectively. Mean daily germination was also the highest in the coir and rockwool media as 4.2 and 4.1, respectively. The germination rate of Astragalus membranaceus was not significantly difference in the media types. Plant height and leaf area of Codonopsis lanceolata were the significantly highest in the rockwool medium as 11.5 cm and $11.3cm^2$, respectively. Longest root length and fresh weight of root were the greatest in the coir medium as 5.8 cm and 0.07 g, respectively. Plant height and leaf area of Astragalus membranaceus were the significantly highest in the coir medium as 14.0 cm and $16.9cm^2$, respectively, and fresh and dry weights of root were the highest in the urethane sponge medium as 0.34 g and 0.03 g, respectively. Therefore, these result suggest that the rockwool and coir media were suitable for the germination and growth during seedling period of Codonopsis lanceolata and Astraglus membranaceus.

• 대한공업교육학회지
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• v.43 no.1
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• pp.1-19
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• 2018

As the BIM designing technology has been applied recently in the construction field, architectural design education in the field of work and university has been changing to 3D modeling. Nevertheless, architectural design & drafting education in the construction specialized vocational high school is not responding appropriately to change. Despite the fact that students need to have 3D modeling design ability, there is a very lack of 3D housing design instructional material that can satisfy the change. The purpose of this study is to develop BIM-based 3D modeling instruction material and apply to analyze effect on interest and task performance ability on Housing Design. The 3D modeling instruction material used in this study was developed through four stages of preparation, development, implementation and evaluation according to the PDIE model procedure. Also, the experimental design model for hypothesis testing was used nonequivalent control group pretest-posttest design. Based on the experimental design model, BIM-based 3D modeling instruction material was performed in the experimental group and 2D CAD-based standard instruction material was taught in the control group. Experimental treatment was conducted on the students of construction specialized vocatinonal high school, and applied to the subject of Professional Drafting in the 12 hours. Before and after the experimental treatment, the interest and task performance ability on Housing Design were tested. Based on the test results, we analyzed the effects of the 3D modeling instruction material through the independent samples t-test. The results of the study are as follows. First, BIM-based 3D modeling instruction material was developed of 'Housing Design & Drafting' unit on the subject of Professional Drafting in construction specialized vocational high school. Second, the application of 3D modeling instruction material has shown to be effective in improving students' interest. Third, the application of 3D modeling instruction material has shown to be effective in improving students' task performance ability on Housing Design.

• Journal of Mushroom
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• v.12 no.4
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• pp.350-356
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• 2014

This study was conducted to evaluate the feeding value of the spent mushroom (Hypsizygus marmoreus) substrates (SMS) in laying hens (Hy-Line Brown). The fresh spent mushroom (Hypsizygus marmoreus) substrates collected from the Namkyung farm were fermented with Bacillus subtilis EJ3 for 2 weeks. A total of twenty-four laying hens were fed corn-soy based experimental diets containing 0% (T0), 5% (T1), 10% (T2) and 15%(T3) fermented SMS for 12 weeks. There were no significant differences among the treatments in egg production, egg weight, egg mass, feed conversion and viability during the experimental period. Feed intake was significantly lowered in T0 (118.3 g) than T1 (121.9 g), T2 (120.3 g) and T3 (122.4 g). There were no significant differences among the treatments eggshell breaking strength, thickness and haugh unit, whereas the yolk color of T1, T2 and T3 were significantly heavy than T0. The palatability of boiled meat was significantly better in the T3 laying hens than in the T0 laying hens. In conclusion, fermented SMS can be used as resource of feed in laying hen feed at 5.0-15% level without effect on performance and egg qualify.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.13 no.2
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• pp.128-133
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• 2010

Purpose: Intussusception is one of the most common causes of an acute abdomen in infancy. The majority of pediatric cases of intussusception are of the ileocolic type and usually idiopathic. Small bowel intussusception is rarely diagnosed in children, and few cases have been reported. The purpose of this study was to determine the clinical features and causes of small bowel intussusception in children. Methods: We retrospectively reviewed the clinical and radiologic findings of 21 children with small bowel intussusception who were admitted to Seoul National University Children's Hospital between March 2005 and January 2010. Results: The clinical presentation of small bowel intussusception included abdominal pain or irritability (85%), vomiting (23%), fever (14%), bloody stools (14%), and abdominal masses (4%). Six patients required surgical management. Ultrasonography showed that the mean diameter of the lesions and mean thickness of the outer rims were 1.6${\pm}$0.7 and 1.7${\pm}$1.8 mm, respectively. Eleven lesions were located in the left abdominal or paraumbilical regions. Children who underwent surgical management were older than children with transient small bowel intussusception (mean age, 51 vs. 109 months). The mean diameter of the lesions and mean thickness of the outer rims were greater in the surgically-managed group. The location of intussusception was not significantly different between the two groups. Conclusion: Small bowel intussusception was spontaneously reduced in a large number of pediatric patients. However, sonographic demonstration of larger size, older age, and pathologic lead point warrant surgical intervention.