• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.37 no.1
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• pp.54-61
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• 2011

Introduction: Bisphosphonates is used widely for the treatment of the Paget's disease, multiple myeloma, bone metastases of malignant tumors with the prevention of pain and their pathological fracture. However, it was recently suggested that bisphosphonates related osteonecrosis of the jaw (BRONJ) is a side effect of bisphosphonate use. Materials and Methods: Twenty-four individuals, who were referred to the Department of Oral and Maxillofacial surgery, Dankook University Dental Hospital, were selected from those who had exposed bone associated with bisphosphonates from January, 2005 to December, 2009 according to the criteria of American Association of Oral and Maxillofacial Surgeons (AAOMS) for BRONJ. The patients group consisted of 7 males and 17 females between the age of 46 to 78 years (average 61.8 years). Each patient had panoramic imaging, computed tomography (CT), whole body bone scanning performed for a diagnosis and biopsy sampling from the necrotizing tissue. C-terminal cross-linking telopeptide of type I collagen (CTX) level of patients who had undergone surgical intervention was measured 7 days before surgery. Results: The main cause of bone exposure was post-extraction (15), chronic periodontitis (4), persistent irritation of the denture (3). Twenty people had undergone BRONJ treatment for two to eight months except for 4 people who had to maintain the bisphosphonates treatment to prevent a metastasis and bone trabecular pain with medical treatment. When the bisphosphonate treatment was suspended at least for 3 months and followed up according to the AAOMS protocols, the exposed necrotizing bones were found to be covered by soft tissue. Conclusion: Prevention therapy, interruption of bisphophonates for at least 3 months and cooperation with the physician for conservative treatment are the essential for treating BRONJ patient with high risk factors. The CTX level of BRONJ patients should be checked before undergoing surgical intervention. Surgical treatments should be delayed in the case of a CTX level <150 pg/mL.

• Korean Journal of Ichthyology
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• v.32 no.3
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• pp.136-142
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• 2020

Morphology and osteology of the slender ribbonfish, Trachipterus ishikawae was described and figured in detail. The morphological characteristics are as follow: body elongate and compressed; upper jaw protrusile; tubercles along ventral edge of body and tail; eyes are large; body naked; caudal fin long and at a right angle to the body; from (3~4)+(7~8) gill rakers; from 180 to 185 dorsal fin rays, from 12 to 13 pectoral fin rays; 9 caudal fin rays and 5+2 short spine at caudal spine. The osteological characteristics are as follow: premaxillary is long and has four teeth; dentary is triangle shape; interopercle and subopercle are wide and flat; 5 branchiostegal rays; post clavicle is thin and long; from 79 to 80 centrum; posterior vertebrae elongate; 5~6 tubercles at urostyle bone.

• Speech Sciences
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• v.9 no.3
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• pp.201-210
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• 2002

This paper explores whether there is correlation between consonants' place and duration of adjacent vowels in English and Korean. The results showed that in English the vowels preceding alveolar stops were in general longer than the vowels before bilabial or velar stops. Consonants appeared to have their inherent length due to their place and to exhibit some compensatory effects on the duration of preceding vowels. This effect can be explained in a physiological term that the tongue tip is the organ which might be more agile in articulatory movement than the tongue body for the velars or the lower lip (and the jaw) for the bilabials is and the shorter production time of the alveolars caused the lengthening of the adjacent vowels. However, this physiological account did not hold in the case of Korean, which exhibited less consistent patterns across speakers for the consonants' place and the vowel duration. The segmental duration seemed to be timed quite consistently within a language but the pattern was not universal across languages.

• Journal of Oral Medicine and Pain
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• v.45 no.1
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• pp.17-21
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• 2020

Osteomyelitis of the jaw infected with Coagulase-Negative Staphylococci (CNS) is rarely reported in the Oral and Maxillofacial Region. Staphylococcus is a part of the normal body flora, but it may be cause severe infections and CNS are often described as the important pathogens in nosocomial infections. Although many studies on prevalence and antibiotics of Staphylococcus aureus have been done, but many of these studies focus only on Methicillin-resistant S. aureus and not on methicillin-resistant coagulase-negative Staphylococci (MRCNS). There was a less study about CNS or MRCNS infections in the Oral and Maxillofacial Region. This report describes a case of a 41-year-old male patient who developed osteomyelitis caused by MRCNS on condyle after open reduction and internal fixation and suggests guideline for the prevention of postoperative infection and appropriate recommendation for treatment and control.

• Fisheries and Aquatic Sciences
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• v.14 no.2
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• pp.148-160
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• 2011

Thirty-one gross abnormalities that have been observed in tilapia are described: 10 fin, five eye, five jaw, four body shape, three head, two yolk sac, one operculum, and conjoined twins. Twenty-one have been described in published papers; the others were obtained from a survey. Breeding experiments revealed that three were heritable, while six were not heritable. Five could be caused by a bacterial infection, and one could be produced by a fungus. Four deformities were in offspring of males that had been injected with methyl methane sulphonate. Three were produced when sperm was treated with methyl methane sulphonate. Six were observed during sex reversal studies, and one was found following heat shock of fertilized eggs. Three were observed in polluted river water. The cause of other deformities is not known.

• Journal of Oriental Neuropsychiatry
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• v.26 no.3
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• pp.267-282
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• 2015

Objectives: Tremor is a common disorder causing abnormal movements, it is defined as, "rhythmic, involuntary movements of a part of the body against ones own volition.". The purpose of this study is to report the effects of Korean Medicine (Acupuncture and herbal-medication) for oromandibular tremor resulting from Deficiency Syndrome. Methods: We treated 6 patients suffering from oromandibular tremor who received hospital treatment in DongEui Medical Center from March to June in 2015. Results: After the treatments, oromandibular tremor decreased or disappeared. And some other accompanying symptoms were improved. Conclusions: These results suggests that Korean medical treatments (Acupuncture and herb-medication) might be effective for treating oromandibular tremor resulting from Deficiency Syndrome.

• Asian-Australasian Journal of Animal Sciences
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• v.24 no.8
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• pp.1053-1059
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• 2011

The objective of this study was to assess the teratogenic and embryotoxic effects of clomiphene citrate in mice. The pregnant mice were administered a single dose of clomiphene citrate at different concentrations i.e 1.0, 2.0, 4.0 and 6.0 ${\mu}g/g$ BW on day 8 of gestation. Fetuses recovered on day 18 of gestation were analyzed on morphological, morphometric and histological basis. Morphological observations showed defects like open eyelids, anophthalmia, fore and hindlimb micromelia, meromelia, amelia, sacral hygroma, hydrocephaly, hemorrhagic spots, kyphosis and clubbed feet. Morphometric analysis indicated a significant (p<0.001) reduction in fetal body weight, crown rump length, head circumference, eye circumference, forelimb and hindlimb lengths and tail size against controls. The histological observations showed brain defects like hydrocephaly, enlarged ventricles and undifferentiated neuroglial cells in cerebellum. Cleft palate, underdeveloped pharynx and atrophy of jaw muscles were the common anatomical defects of pharyngeal region. It is concluded that the concentrations of clomiphene citrate used during the present study proved teratogenic in mice fetuses.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.55 no.5
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• pp.736-741
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• 2022

A single specimen (91.5 cm standard length) of the salmonid species, Oncorhynchus tshawytscha (Walbaum, 1792) was collected on April 19, 2022 in Sokcho-si, Gangwon-do, Korea. O. tshawytscha has the following morphological characteristics: base of lower jaw teeth is black, black spots are scattered on the dorsal section of body, and the edge of caudal fin is black. Although the species is morphologically similar to Oncorhynchus kisutch, O. tshawytscha differs from it in having black spots on the caudal fin. Molecular analysis results based on mitochondrial cytochrome c oxidase subunit I (COI) sequences showed that our specimen perfectly matched with the COI sequences of O. tshawytscha registered at the NCBI. Therefore, we suggest the new Korean name 'Wang-yeon-eo' for O. tshawytscha.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.46 no.4
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• pp.240-249
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• 2020

Objectives: Although the side effects of radiation therapy vary from mucositis to osteomyelitis depending on the dose of radiation therapy, to date, an experimental animal model has not yet been proposed. The aim of this study was to develop an animal model for assessing complications of irradiated bone, especially to quantify the dose of radiation needed to develop a rat model. Materials and Methods: Sixteen Sprague-Dawley rats aged seven weeks with a mean weight of 267.59 g were used. Atraumatic extraction of a right mandibular first molar was performed. At one week after the extraction, the rats were randomized into four groups and received a single dose of external radiation administered to the right lower jaw at a level of 14, 16, 18, or 20 Gy, respectively. Clinical alopecia with body weight changes were compared and bony volumetric analysis with micro-computed tomography (CT), histologic analysis with H&E were performed. Results: The progression of the skin alopecia was different depending on the irradiation dose. Micro-CT parameters including bone volume, bone volume/tissue volume, bone mineral density, and trabecular spaces, showed no significant differences. The progression of osteoradionecrosis (ORN) along with that of inflammation, fibrosis, and bone resorption, was found with increased osteoclast or fibrosis in the radiated group. As the radiation dose increases, osteoclast numbers begin to decrease and osteoclast tends to increase. Osteoclasts respond more sensitively to the radiation dose, and osteoblasts are degraded at doses above 18 Gy. Conclusion: A standardized animal model clinically comparable to ORN of the jaw is a valuable tool that can be used to examine the pathophysiology of the disease and trial any potential treatment modalities. We present a methodology for the use of an experimental rat model that incorporates a guideline regarding radiation dose.

• Korean Journal of Environmental Biology
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• v.18 no.4
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• pp.387-394
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• 2000

The morphological characteristics between male and female of three species, Chaenogobius urotaenia, C. sp. MR, C. sp. BW, collected from June 1996 to Aug. 1999, Korea was studied. Of 13 characters to be studied, 12 characters with exception of caudal fin ray length were significantly different among three species and these three species were distinguished each other by the results of the multiple comparison test (REGWQ test). Interspecific differences in female was distinct in body depth, head length, caudal peduncle length, caudal peduncle depth, snout length, pectoral fin ray length; In particular, C. sp. MR was shorter in upper jaw length, anal fin ray length and eye diameter, and to be smaller in head depth and head width than other two species. Chaenogobius urotaenia was longer in pelvic fin ray length. In case of male, there was not characters to distinguish each one among three species; Chaenogobius urotaenia was longer in head length, eye diameter and pelvic fin ray length than other two species, C. sp. MR to be longer in caudal peduncle length, but shorter in snout length and anal fin ray length, and to be lower in head depth. C. sp. BW was higher in body depth and caudal peduncle depth, and to be longer in upper jaw length and pectoral fin ray length. Both of male and female among three species didn't have any difference in caudal fin ray length. [Chaeogobius urotaenia, C. sp. MR, C. sp. BW, morphological characteristics].