• Biomolecules & Therapeutics
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• v.26 no.2
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• pp.167-174
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• 2018

Alterations in sulfur amino acid metabolism are associated with an increased risk of a number of common late-life diseases, which raises the possibility that metabolism of sulfur amino acids may change with age. The present study was conducted to understand the age-related changes in hepatic metabolism of sulfur amino acids in 2-, 6-, 18- and 30-month-old male C57BL/6 mice. For this purpose, metabolite profiling of sulfur amino acids from methionine to taurine or glutathione (GSH) was performed. The levels of sulfur amino acids and their metabolites were not significantly different among 2-, 6- and 18-month-old mice, except for plasma GSH and hepatic homocysteine. Plasma total GSH and hepatic total homocysteine levels were significantly higher in 2-month-old mice than those in the other age groups. In contrast, 30-month-old mice exhibited increased hepatic methionine and cysteine, compared with all other groups, but decreased hepatic S-adenosylmethionine (SAM), S-adenosylhomocysteine and homocysteine, relative to 2-month-old mice. No differences in hepatic reduced GSH, GSH disulfide, or taurine were observed. The hepatic changes in homocysteine and cysteine may be attributed to upregulation of cystathionine ${\beta}-synthase$ and down-regulation of ${\gamma}-glutamylcysteine$ ligase in the aged mice. The elevation of hepatic cysteine levels may be involved in the maintenance of hepatic GSH levels. The opposite changes of methionine and SAM suggest that the regulatory role of SAM in hepatic sulfur amino acid metabolism may be impaired in 30-month-old mice.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.10 no.2
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• pp.1-30
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• 2006

Maek Kyoung(Mai Jing, 脈經) is the first chinese specialized book of diagnostics written by Wang Hee(Wang xi, 王熙) from Seo Jin(xi jin, 西晉). He assorted the contents with pulse and medical examination from Nae Kyoung(nei jing, 內經), Nan Kyoung(nan jing, 難經), Sang Han Ron(shang han lun, 傷寒論) and Jung Jang Kyoung(zhong cang jing, 中藏經). And united with his own research, he explains medical examination and the way of talking the pulse by classifying into entrance and class. Maek Kyoung(Mai Jing, 脈經) was imported Korea by Ji Chong(zhi cong, 知聰) AD 561, and he passed through Ko Ku Ryeo(gao gou li, 高句麗) with Nae Wei Jeon(nei wai dian, 內外典), Yak Seo(yao shu, 藥書), Myung Dang Do(ming tang tu, 明堂圖) and MaekKyoung(Mai Jing, 脈經) to be naturalized in Japan. This treatise make a special study of the second volume of the Maek Kyoung. It consists of the four chapters : Pyoung Sam Kwan Eum Yang E Sip Sa Ki Maek Je I1(平三關陰陽二十四氣脈第一), Pyoung In Young Sin Mun Ki Ku Jeon Hu Maek Je E(平人迎神門氣口前後脈第二), Pyoung Sam Kwan Byoung Hu Byoung Chi Eui Je Sam(平三關病侯幷治宜第三), and Pyoung Gi Kyoung Pal Maek Byoung Je Sa(平奇經八脈病第四). Bi Geup Choun Geum Yo Bang(備急千金要方) and Eui Hak Ip Mun(醫學入門) quoted from the contents in the second volume of Maek Kyoung, and Bin Ho Maek Hak(瀕湖脈學), Gi Kyoung Pal Maek Go(奇經八脈攷) and Maek Eo(脈語) extracted from contents in the second volume of the Maek Kyoung and requoted from this contents. Contents in the second volume of the Maek Kyoung have very valuable data like that, but the literature on this subject in the form of a treatise has not been yet in Korea. So I hope this study will be useful to develope Diagnostics by correcting translation and interpretation and fixing wrong translation.

• Journal of Korean Medical classics
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• v.11 no.2
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• pp.146-168
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• 1998

This thesis is a study on the diagnostic theory and methods of Macjin(checking of pulse) as described in the Whang Di Nei Qing. There are four methods of Macjin in this text, namely: Dong Macjin(動脈法), Sam Bu Gu Who Macjin(三部九脈診). In Young Gi Gu Macjin(人迎氣口脈診法), Nei Qing's Gi Gu Macjin(內徑의 氣口脈法). Each method developed in it's own way, but they are all closely related and became the basis of today's Macjin. I examined the methods of Macjin in the Whang Di Nei Qing from a perspective of "change". The main questions of this study are: "What brought about the development of the different methods?". "How do the methods differ?", and "how did these methods evoke into today's Macjin?". The method of Macjin generated spontaneously from the observation and treatment of disease. Dong Macjin was the first method developed and became the basis of subsequent forms of Macjin. The accumulation of medical knowledge and the influence of oriental philosophy fueled the evolution of Macjin. Chronologically, Macjin methods developed starting with Dong Macjin and eventually into Sam Bu Gu Who Macjin. In Young Gi Gu Macjin, and Nei Qing's Gi Gu Macjin. The different methods of Macjin vary in how many pulse points are checked, and were established with simplicity and effectiveness in mind. Dong Macjin involves the checking the whole body. Sam Bu Gu Who Macjin involves nine points. In Young Gi Gu Macjin involves four points. and Nei Qing's Gi Gu Macjin involves two. In it's early development, the checking of a patient's pulse was used to diagnose only localized disorders in comparison with symptoms. It evolved with Oh Jang Mad(五臟脈, five main types of pulse) to be able to check internal organs with the introduction of Nei Qing's Gi Gu Macjin. After the division of Chon Kwan Chuck(寸關尺), it evolved further to be able to make a detailed diagnosis by using the result of pules checks. Nowadays, we can make 28 forms of diagnostic indices from these development. In conclusion, Macjin can be used practically and effectively in the diagnosis of disease. In using three methods of Macjin(In Young Gi Gu Macjin, Nei Qing's Gi Gu Macjin, and today's Gi Gu Macjin, which can determine the whole body's Siate of well-being) in conjunction with Dong Macjin(which helps pinpoint the localized disorder), an exact diagnosis can be obtained. I strongly feel that we should acquire objectivity by accommodating Macjin with modern methods of medicine.

• Journal of the Korean Society for Library and Information Science
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• v.17
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• pp.11-47
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• 1989

This study intends to examine the background and the procedure of the carving of the tablets of the second edition of Dae-Jang-Mock­Lock(재조대장목록). the time and the route of the moving of the tablets. into Haein-sa, and the contents and the system of it. This study is mainly based on the second edition of Dae-Jang-Mock-Lock. But the other closely related materials such as restored first. edition of the Dae- Jang-Mock-Lock, Koryo Sin-Jo-Dae-Jang-Byeol-Lock (고려신조대장교정별록). Kae-Won-Seok-Kyo-Lock (개원석교록). Sok-Kae­Won-Seok-Kyo-Lock (속개원석교록). Jeong-Won-Sin-Jeong-Seok-Kyo­Lock(정원신정석교록), Sok-Jeong-Won-Seok-Kyo-Lock(속정원석교록), Dea-Jung-Sang-Bu-Beob-Bo-Lock(대중상부법보록), and Kyeong-Woo-Sin-Su-Beob-Bo-Lock(경우신수법보록), are also analysed and closely examined. The results of this study can be summarized as follows: 1. The second edition of Tripitaka Koreana(고려대장경) was carved for the purpose of defending the country from Mongolia with the power of Buddhism, after the tablets of the first edition in Buin-sa(부이사) was destroyed by fire. 2. In 1236. Dae-Jang-Do-Gam(대장도감) was established, and the preparation for the recarving of the tablets such as comparison between the content, of the first edition of Tripitalk Koreana, Gal-Bo-Chik-Pan-Dae­Jang-Kyeong and Kitan Dae- Jang-Kyeong, transcription of the original copy and the preparation of the wood, etc. was started. 3. In 1237 after the announcement of Dae-Jang-Gyeong-Gak-Pan-Gun­Sin-Gi-Go-Mun(대장경핵판군신석고문), the carving was started on a full scale. And seven years later (1243), Bun-Sa-Dae-Jang-Do-Gam(분사대장도감) was established in the area of the South to expand and hasten the work. And a large number of the tablets were carved in there. 4. It took 16 years to carve the main text and the supplements of the second edition of Tripitaka Koreana, the main text being carved from 1237 to 1248 and the supplement from 1244 to 1251. 5. It can be supposed that the tablets of the second edition of Tripitaka Koreana, stored in Seon-Won-Sa(선원사), Kang-Wha(강화), for about 140 years, was moved to Ji-Cheon-Sa(지천사), Yong-San(용산), and to Hae-In-Sa(해인사) again, through the west and the south sea and Jang-Gyeong-Po(장경포), Go-Ryeong(고령), in the autumn of the same year. 6. The second edition of Tripitaka Koreana was carved mainly based on the first edition, comparing with Gae-Bo-Chik-Pan-Dae-Jang-Kyeong(개보판대장경) and Kitan Dae-Jang-Kyeong(계단대장경). And the second edition of Dae-Jang-Mock-Lock also compiled mainly based on the first edition with the reference to Kae-Won-Seok-Kyo-Lock and Sok-Jeong-Won-Seok-Kyo-Lock. 7. Comparing with the first edition of Dae-Jang-Mock-Lock, in the second edition 7 items of 9 volumes of Kitan text such as Weol-Deung­Sam-Mae-Gyeong-Ron(월증삼매경론) are added and 3 items of 60 volumes such as Dae-Jong-Ji-Hyeon-Mun-Ron(대종지현문논) are substituted into others from Cheon chest(천함) to Kaeng chest(경함), and 92 items of 601 volumes such as Beob-Won-Ju-Rim-Jeon(법원주임전) are added after Kaeng chest. And 4 items of 50 volumes such as Yuk-Ja-Sin-Ju-Wang-Kyeong(육자신주왕경) are ommitted in the second edition. 8. Comparing with Kae-Won-Seok-Kyo-Lock, Cheon chest to Young chest (영함) of the second edition is compiled according to Ib-Jang-Lock(입장록) of Kae-Won-Seok-Kyo-Lock. But 15 items of 43 vol­umes such as Bul-Seol-Ban-Ju-Sam-Mae-Kyeong(불설반주삼매경) are ;added and 7 items of 35 volumes such as Dae-Bang-Deung-Dae-Jib-Il­Jang-Kyeong(대방등대집일장경) are ommitted. 9. Comparing with Sok-Jeong-Won-Seok-Kyo-Lock, 3 items of the 47 volumes (or 49 volumes) are ommitted and 4 items of 96 volumes are ;added in Caek chest(책함) to Mil chest(밀함) of the second edition. But the items are arranged in the same order. 10. Comparing with Dae- Jung-Sang-Bo-Beob-Bo-Lock, the arrangement of the second edition is entirely different from it. But 170 items of 329 volumes are also included in Doo chest(두함) to Kyeong chest(경함) of the second edition, and 53 items of 125 volumes in Jun chest(존함) to Jeong chest(정함). And 10 items of 108 volumes in the last part of Dae-Jung-Sang-Bo-Beob-Bo-Lock are ommitted and 3 items of 131 volumes such as Beob-Won-Ju-Rim-Jeon(법원주임전) are added in the second edition. 11. Comparing with Kyeong-Woo-Sin-Su-Beob-Bo-Lock, all of the items (21 items of 161 volumes) are included in the second edition without ;any classificatory system. And 22 items of 172 volumes in the Seong­Hyeon-Jib-Jeon(성현집전) part such as Myo-Gak-Bi-Cheon(묘각비전) are ommitted. 12. The last part of the second edition, Joo chest(주함) to Dong chest (동함), includes 14 items of 237 volumes. But these items cannot be found in any other former Buddhist catalog. So it might be supposed as the Kitan texts. 13. Besides including almost all items in Kae-Won-Seok-Kyo-Lock and all items in Sok-Jeong-Won-Seok-Kyo-Lock, Dae-Jung-Sang-Bo­Beob-Bo-Lock, and Kyeong-Woo-Sin-Su-Beob-Bo-Lock, the second edition of Dae-Jang-Mock-Lock includes more items, at least 20 items of about 300 volumes of Kitan Tripitaka and 15 items of 43 volumes of traditional Korean Tripitake that cannot be found any others. Therefore, Tripitaka Koreana can be said as a comprehensive Tripitaka covering all items of Tripitakas translated in Chinese character.

• Journal of Wetlands Research
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• v.14 no.2
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• pp.277-288
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• 2012

Estuary is unique habitat ground under substantial changes of water quality, river side, bed material, and micro topography. Construction of SinGok underwater weir with excessive dredging for downstream of weir has changed hydraulic conditions of Han River. This study investigates spatial changes of estuary and expansion process of vegetation on sandbar for JangHang estuary in Han River through analysis of physical and ecological characteristics. As a result of investigation, we found that area of sandbar in JangHang estuary is expanded six times compared between 1985 and 2006, and area of Phragmites australis is gradually decreased while area of Salix subfragilis Anderson. is increased. Also the analysis result of soil layer shows that the Jang-Hang wetlands are created by effect from river, and woody plants are settled from middle part of wetlands, then spread to upper and lower part of wetlands.

• Journal of Astronomy and Space Sciences
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• v.28 no.1
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• pp.79-91
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• 2011

Ongnu (Jade Clepsydra; also called Heumgyeonggaknu) is a water clock was made by Jang Yeong-sil in 1438. It is not only an automatic water clock that makes the sound at every hour on the hour by striking bell, drum and gong, but also an astronomical clock that shows the sun's movement over time. Ongnu's power mechanism used is a water-hammering method applied to automatic time-signal device. The appearance of Ongnu is modeled by Gasan (pasted-paper imitation mountain) and Binpungdo (landscape of farming work scene) is drawn at the foot of the mountain. The structure of Ongnu is divided into the top of the mountain, the foot of the mountain and the flatland. There located are sun-movement device, Ongnyeo (jade female immortal; I) and Four gods (shaped of animal-like immortals) at the top of the mountain, Sasin (jack hour) and Musa (warrior) at the foot of the mountain, and Twelve gods, Ongnyeo (II) and Gwanin on the flatland. In this study, we clearly and systematically understood the time-announcing mechanism of each puppet. Also, we showed the working mechanism of the sun-movement device. Finally, we completely established the 3D model of Ongnu based on this study.

• Journal of Distribution Science
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• v.10 no.9
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• pp.23-29
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• 2012

Purpose - The main purpose of this study is to find consumers' usage behavior in mobile services. To achieve these research goals, we empirically estimate the relationship between characteristics related to the use and provision of mobile services and factors influencing consumers' intentions. Research design / data / methodology - This study based on TAM, in which behavior is seen as a consequence of affect and intentions and used the theory of consumption values which is a means of explaining user decisions to employ a utilitarian and hedonic facet using by smart phone. Results - The result of the study verified that specific factors, such as expectations about pleasure and monetary value, had the biggest influence on the service usage pattern of mobile consumers. And typically, when consumers are expected to monetary damages, it will be avoided. However, in result of this study, it was found that mobile service users pay a high cost, but they are in pursuit of pleasure and fun. Conclusions - These results, a variety of applications in the mobile service are being provided to users. As information technology has developed, companies should have providing diverse application programs and good quality of services with advanced information technology.

• Journal of the Korean Institute of Rural Architecture
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• v.5 no.3
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• pp.1-7
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• 2003

This study is to find out the betterment way of cost down in the architectural temporary work. To do so, it is more important to check every case above all and find and choice optimum way fitting a scene of a construction field. In addition, in case that the way to apply in proportion to a given condition is complicated, the way to find out cost down way is to adopt the individual peculiarity instead of the generality. Hereupon this study is rather to find out the better way to reduce such as material and manpower cost than to leave matters not to be settled to get the best way in the existing temporary work. So this study is composed with finding the existing problems, fixing the focus about the developmental way to reduce cost in the exterior and interior temporary work, presenting the new construction way and describing the merits and attentions of an improved exterior and interior temporary work.

• International Journal of Highway Engineering
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• v.10 no.3
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• pp.79-86
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• 2008

This paper proposed the appropriate installation angle of skewed sensors for measuring vehicle wandering data, which are collected to figure out the location of dynamic weight of a moving vehicle on roadways. We developed a device using tape-switch sensors and a computer program and collected vehicle wandering data with the device and probe vehicles. As a result, the steeper the skewed sensor was installed, the lower the error was shown. However, we could not collect proper data when a skewed sensor was set up higher than $30^{\circ}$ due to tandem axle. Therefore, this study suggested the appropriate angle of skewed sensors as a degree of $20^{\circ}$ to $25^{\circ}$ for gathering wandering data.

• International Journal of Control, Automation, and Systems
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• v.6 no.6
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• pp.873-883
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• 2008

This paper presents a parametric study on the controller design scheme for a gyro-accelerometer to have robust performance under some parameter variations. In particular, an integral and derivative based controller design method is suggested to achieve the desired performances of stability margin, bandwidth, and uniformity of scale for both gyroscopes and accelerometers with uncertainties of quality factor and resonant frequency. The simulation result shows that the control loop based on the suggested method gives satisfactory performance robustness under parameter variations, demonstrating the usefulness of the proposed design scheme.