We examine the current status of smart factory deployment and diffusion programs in Korea, and seek to promote manufacturing innovation from the perspective of SMEs. The main conclusions of this paper are as follows. First, without additional market creation and supply chain improvement, smart factories are unlikely to raise profitability leading to overinvestment. Second, new business models need to connect "manufacturing process efficiency" with "R&D" and "marketing" in value chain in smart factories. Third, when introducing smart factories, we need to focus on the areas where process-embedded technology is directly linked to corporate competitiveness. Based on the modularity-maturity matrix (Pisano and Shih, 2012) and the examples of U.S. Manufacturing Innovation Institute (MII), we establish the new smart factory deployment policy measures as follows. First, we shift our smart factory strategy from quantitative expansion to qualitative upgrading. Second, we promote by each sector the formation of industrial commons that help SMEs to jointly develop R&D, exchange standardized data and practices, and facilitate supplier-led procurement system. Third, to implement new technology and business models, we encourage partnerships, collaborations, and M&As between conventional SMEs and start-ups and business ventures. Fourth, the whole deployment process of smart factories is indexed in detail to identify the problems and provide appropriate solutions.
The coastal plains of the Puna and Ka' u Districts of the island of Hawaii are a contradiction to the popular view that the island of Hawaii is a tropical rain forest or a vegetated landscape with abundant water sour This section of the island lies in the rain shadow of Mauna Loa a Kilauea Volcanoes and receives less than 30 inches of annual precipita When rain does come. it is in the form of sudden down pours. givi residents of the area little time to collect and conserve water. Due to porous nature of the rock. there is no standing surface water. In spite of these harsh climatic conditions. archeological evidence indic that an extensive agriculture complex existed not only along the coast. into the most remote parts of what is called the Ka'u Desert. Pass through these agricultural areas are historic and pre - historic t systems. These trail systems apparently played a significant suppor role for exchange between the ahupua's (classic land divisions of Haw and the geopolitical districts. The question arises as to how could vast agricultural complexes a heavy foot travel over miles of arid land exist without dependable wa sources\ulcorner While planting - pits and mounds were designed to make most efficient use of available water and conserve moisture(Carter 19 9). people involved in planting also needed potable water for surv Most publications and research papers dealing with the early population this area make only oblique reference to springs and wells which t populations depended upon. The Federal Cave Resource Protection Act(1988) has served as imprtus for the National Park Service to look closer at the lava tu caves and fault cracks within Hawaii Volcanoes National Park. P visitors to these underground areas found large volumes of standing wa in fault cracks. and abundant drip areas with the lava tubes. Re observes noted that in most cases. where the cracks and caves we located in the arid sections of the park. there has been extens modifiacation or utilization of these water sources by the early Hawaii and others. The variety of western containers used for collection indica that these water sources were used during historic times. William E described similar water sources in his narrative of his trip around island in 1823(Eills 1979), This report is directed at documenting recent observations and a stimulating further research into early Hawaiian water collection syst It also explores the implications that power and political influence of e chiefs in the arid portions of Hawaii could have been linked to the con of the water resources.
Darlene Mae D., Ortiz;Mikyung, Kim;Hyun Jun, Lee;Chrislean Jun, Botanas;Raly James Perez, Custodio;Leandro, Val Sayson;Nicole, Bon Campomayor;Chaeyeon, Lee;Yong Sup, Lee;Jae Hoon, Cheong;Hee Jin, Kim
Biomolecules & Therapeutics
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v.31
no.2
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pp.227-239
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2023
Major depressive disorder is a leading cause of disability in more than 280 million people worldwide. Monoamine-based antidepressants are currently used to treat depression, but delays in treatment effects and lack of responses are major reasons for the need to develop faster and more efficient antidepressants. Studies show that ketamine (KET), a PCP analog, produces antidepressant effects within a few hours of administration that lasts up to a week. However, the use of KET has raised concerns about side effects, as well as the risk of abuse. 4 -F-PCP analog is a novel PCP analog that is also an NMDA receptor antagonist, structurally similar to KET, and might potentially elicit similar antidepressant effects, however, there has been no study on this subject yet. Herein, we investigate whether 4-F-PCP displays antidepressant effects and explored their potential therapeutic mechanisms. 4-F-PCP at 3 and 10 mg/kg doses showed antidepressant-like effects and repeated treatments maintained its effects. Furthermore, treatment with 4-F-PCP rescued the decreased expression of proteins most likely involved in depression and synaptic plasticity. Changes in the excitatory amino acid transporters (EAAT2, EAAT3, EAAT4) were also seen following drug treatment. Lastly, we assessed the possible side effects of 4-F-PCP after long-term treatment (up to 21 days). Results show that 4-F-PCP at 3 mg/kg dose did not alter the cognitive function of mice. Overall, current findings provide significant implications for future research not only with PCP analogs but also on the next generation of different types of antidepressants.
Proceedings of the Korea Water Resources Association Conference
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2023.05a
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pp.32-32
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2023
Incidences of urban flood and extreme heat waves (due to the urban heat island effect) are expected to increase in New Zealand under future climate change (IPCC 2022; MfE 2020). Increasingly, the mitigation of such events will depend on the resilience of a range Nature-Based Solutions (NBS) used in Sustainable Urban Drainage Schemes (SUDS), or Water Sensitive Urban Design (WSUD) (Jamei and Tapper 2019; Johnson et al 2021). Understanding the impact of changing precipitation and temperature regimes due climate change is therefore critical to the long-term resilience of such urban infrastructure and design. Cuthbert et al (2022) have assessed the trade-offs between the water retention and cooling benefits of different urban greening methods (such as WSUD) relative to global location and climate. Using the Budyko water-energy balance framework (Budyko 1974), they demonstrated that the potential for water infiltration and storage (thus flood mitigation) was greater where potential evaporation is high relative to precipitation. Similarly, they found that the potential for mitigation of drought conditions was greater in cooler environments. Subsequently, Jaramillo et al. (2022) have illustrated the locations worldwide that will deviate from their current Budyko curve characteristic under climate change scenarios, as the relationship between actual evapotranspiration (AET) and potential evapotranspiration (PET) changes relative to precipitation. Using the above approach we assess the impact of future climate change on the urban water-energy balance in three contrasting New Zealand cities (Auckland, Wellington, Christchurch and Invercargill). The variation in Budyko curve characteristics is then used to describe expected changes in water storage and cooling potential in each urban area as a result of climate change. The implications of the results are then considered with respect to existing WSUD guidelines according to both the current and future climate in each location. It was concluded that calculation of Budyko curve deviation due to climate change could be calculated for any location and land-use type combination in New Zealand and could therefore be used to advance the general understanding of climate change impacts. Moreover, the approach could be used to better define the concept of urban infrastructure resilience and contribute to a better understanding of Budyko curve dynamics under climate change (questions raised by Berghuijs et al 2020)). Whilst this knowledge will assist in implementation of national climate change adaptation (MfE, 2022; UNEP, 2022) and improve climate resilience in urban areas in New Zealand, the approach could be repeated for any global location for which present and future mean precipitation and temperature conditions are known.
James Ban;Chuan Ma;Sorrasak Vachirapanyakun;Pasin Plodpradit;Goangseup Zi
Journal of the Korea institute for structural maintenance and inspection
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v.27
no.4
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pp.33-44
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2023
Wind power is one of the most efficient and reliable energy sources in the transition to a low-carbon society. In particular, offshore wind power provides a high-quality and stable wind resource compared to onshore wind power while both present a higher installed capacity than other renewables. In this paper, we present our new program, the X-WIND program well suitable for the assessment of the substructure of offshore wind turbines. We have developed this program to increase the usability of analysis programs for offshore wind energy substructures by addressing the shortcomings of existing programs. Unlike the existing programs which cannot solely perform the substructure analyses or lack pre-post processors, our X-WIND program can complete the assessment analysis for the offshore wind turbines alone. The X-WIND program is embedded in AutoCAD so that both design and analysis are performed on a single platform. This also performs static and dynamic analysis for wind, wave, and current loads, essential for offshore wind power structures, and includes pre/post processors for designs, mesh developments, graph plotting, and code checking. With this expertise, our program enhances the usability of analysis programs for offshore wind energy substructures, promoting convenience and efficiency.
As recent advances in science, technology and performance requirements of the weapons system are getting highly diversified and complex, the performance requirements also get stringent and strict. Moreover, the weapons system should be intimately connected with other systems such as watchdog system, command and control system, C4I system, etc. However, a tremendous amount of time, cost and risk being spent to acquire new weapons system, and not being diminished compared to the rapid pace of its development speed. Defense Modeling and Simulation(M&S) comes into the spotlight as an alternative to overcoming these difficulties as well as constraints. In this paper, we propose the development process of virtual test framework based on the synthetic environment as a tool to analyze the effectiveness of the weapons system of underwater engagement model. To prove the proposed concept, we develop the test-bed of virtual test using Delta3D simulation engine, which is open source S/W. We also design the High Level Architecture and Real-time Infrastructure(HLA/RTI) based Federation for the interoperation with heterogeneous simulators. The significance of the study entails (1)the rapid and easy development of simulation tools that are customized for the Korean Theater of War; (2)the federation of environmental entities and the moving equations of the combat entities to manifest a realistic simulation.
The structural and sustainable implementation of the microfinance policy is required to be successful. To this end, the government should focus on availability and accessibility of the public microfinance, away from providing the beneficial financing (financial benefits)featured by the combination of the welfare and finance in the past. In addition, the government-sponsored microfinance needs to aim for performance-oriented evaluation that leads to stabilization of financial life of ordinary people or increase of income, moving away from conventional funding based on the scale and the quantity for the poor. It is necessary to implement the following policies in order for the Moon's administration to take the government-sponsored microfinance to the next level. The government-sponsored microfinance must be in the market failure domain, but nonetheless, it is required to be managed by structural and sustainable ways so that it complies with the market principles and does not crowd out the private microfinance. Last but not least, making the best use of the capital market function can be a way to fund social enterprises or social economy enterprises. This aims to enable catalyst capital in the capital market to play a prime role for the inflow of private capital for the purpose of creating the social value.
The main purpose of this paper is to examine Putnam's recent conception of ethics, and show that it gives rise to an ineluctable incoherence with his rationalism. This suggests that Putnam's philosophy has to be far more naturalized to make his new position cogent. Putnam recently has shown some explicit turn toward pragmatism a la James and Dewey under the name of "pragmatic pluralism." Putnam says that traditional ethics has presupposed some form of ontology in one way or another, which he sees is based on an unnecessary pursuit of a misleading conception of objectivity. Putnam tries to get rid of any notion of ontology in ethics, whereby we can talk about a third view which runs between traditional objectivism and nihilistic relativism. In this sense, he defines pragmatism as "fallibilism cum antiskepticism." Putnam's suggestion makes a good sense as far as it goes. However, his continuous transition toward pragmatism is critically impeded by his own adhesion to the normative conception of "reason." In this light, Putnam himself is wobbling between Kant and Dewey, just as he describes ethics is. Dewey's pragmatism does not have recourse to the very notion of reason to secure objectivity necessary to make sense of moral experience. Putnam needs to be far more naturalized to reach cogently where he espouses, and this can be done only by renouncing the normative conception of reason.
Asia-Pacific Journal of Business Venturing and Entrepreneurship
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v.18
no.4
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pp.177-191
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2023
This study analyzes the types of linkages between major projects used by firms that attracted venture capital among firms that received government support in the field of SME startups. It identifies the types of linkages between support programs related to attracting venture investment and verifies the usefulness of integrated and cooperative support. The main findings of this study are as follows. First, Startup Success Packages, Startup Foundation Funds*, Youth Entrepreneurship Centers, and Training are the main programs used by startups and venture firms, and support-implementing agencies use these programs to provide support for each stage of growth. Second, the majority of startups and venture firms receiving policy support for job creation and manpower enhancement projects. Third, export-type growth companies receive continuous support from MSS, MOTIE, MSIT, and KIPO. Fourth, job creation programs drive the employment performance and creation of companies. Fifth, local government support projects tend to rely heavily on central government support programs. Sixth, growth companies in the startup and venture sector have a clear link to credit guarantee scheme by KIBO. These findings provide empirical evidence on the necessity and feasibility of integrated and collaborative support, and are expected to contribute to the direction of better support policies.
Harpriya Kaur;Steven J. Wurzelbacher;P. Tim Bushnell;Stephen Bertke;Alysha R. Meyers;James W. Grosch;Steven J. Naber;Michael Lampl
Safety and Health at Work
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v.14
no.4
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pp.406-414
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2023
Background: This study examined age-group differences in the rate, severity, and cost of injuries among construction workers to support evidence-based worker safety and health interventions in the construction industry. Methods: Ohio workers' compensation claims for construction workers were used to estimate claim rates and costs by age group. We analyzed claims data auto-coded into five event/exposure categories: transportation incidents; slips, trips, and falls (STFs); exposure to harmful substances and environments; contact with objects and equipment (COB); overexertion and bodily reaction. American Community Survey data were used to determine the percentage of workers in each age group. Results: From 2007-2017, among 72,416 accepted injury claims for ~166,000 construction full-time equivalent (FTE) per year, nearly half were caused by COB, followed by STFs (20%) and overexertion (20%). Claim rates related to COB and exposure to harmful substances and environments were highest among those 18-24 years old, with claim rates of 313.5 and 25.9 per 10,000 FTE, respectively. STFs increased with age, with the highest claim rates for those 55-64 years old (94.2 claims per 10,000 FTE). Overexertion claim rates increased and then declined with age, with the highest claim rate for those 35-44 years old (87.3 per 10,000 FTE). While younger workers had higher injury rates, older workers had higher proportions of lost-time claims and higher costs per claim. The total cost per FTE was highest for those 45-54 years old ($1,122 per FTE). Conclusion: The variation in rates of injury types by age suggests that age-specific prevention strategies may be useful.
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