• 제목/요약/키워드: Jacob

검색결과 167건 처리시간 0.026초

Direct Somatic Embryogenesis of Curculigo orchioides Gaertn., an Endangered Medicinal Herb

  • Thomas, T.Dennis;Jacob, Alphonsa
    • Journal of Plant Biotechnology
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    • 제6권3호
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    • pp.193-197
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    • 2004
  • In vitro multiplication of Curculigo orchioides was achieved by direct somatic embryogenesis in young leaf segments. Immature leaf segments of about 0.5 cm in length were cultured on MS medium supplemented with different concentrations of BAP (2-10 $\mu{M}$) or Kin (2-10 $\mu{M}$). Optimum response in terms of per cent cultures responding (89%) and the number of embryos per explant (16) were observed on MS medium supplemented with 8 $\mu$M BAP. The emergence of several somatic embryos on the adaxial side of the leaf segments was observed one month after the culture. Germinated somatic embryos were grown up to about 1.5 cm length before transferring to maturation medium. For maturation, the individual embryos were isolated and transferred to MS medium supplemented with BAP (5 $\mu{M}$) and NAA (0.5 $\mu{M}$). The plantlets emerged from the embryos were transferred to soil containing 1 peat: 1 sand with 90% success. The embryos were formed directly on the leaf segments without any callus phase. Direct regeneration of somatic embryos is important for the conservation of this endangered species, as rare somaclonal variants are likely to arise than from indirect regeneration.

Topic Level Disambiguation for Weak Queries

  • Zhang, Hui;Yang, Kiduk;Jacob, Elin
    • Journal of Information Science Theory and Practice
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    • 제1권3호
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    • pp.33-46
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    • 2013
  • Despite limited success, today's information retrieval (IR) systems are not intelligent or reliable. IR systems return poor search results when users formulate their information needs into incomplete or ambiguous queries (i.e., weak queries). Therefore, one of the main challenges in modern IR research is to provide consistent results across all queries by improving the performance on weak queries. However, existing IR approaches such as query expansion are not overly effective because they make little effort to analyze and exploit the meanings of the queries. Furthermore, word sense disambiguation approaches, which rely on textual context, are ineffective against weak queries that are typically short. Motivated by the demand for a robust IR system that can consistently provide highly accurate results, the proposed study implemented a novel topic detection that leveraged both the language model and structural knowledge of Wikipedia and systematically evaluated the effect of query disambiguation and topic-based retrieval approaches on TREC collections. The results not only confirm the effectiveness of the proposed topic detection and topic-based retrieval approaches but also demonstrate that query disambiguation does not improve IR as expected.

Exploring Reliability of Oriented Strand Board's Tensile and Stiffness Strengths

  • Wang, Y.;Young, T.M.;Guess, F.M.;Leon, R.V.
    • International Journal of Reliability and Applications
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    • 제8권1호
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    • pp.111-124
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    • 2007
  • In this paper, we apply insightful statistical reliability tools to manage and seek improvements in the strengths of Oriented Strand Board (OSB). As a part of the OSB manufacturing process, the product undergoes destructive testing at various intervals to determine compliance with customers' specifications. Workers perform these tests on sampled cross sections of the OSB panel to measure the tensile strength, also called internal bond (IB), in pounds per square inches until failure. Additional stiffness strength tests include parallel and perpendicular elasticity indices (EI), which are taken from cross sectional samples of the OSB panel in the parallel and perpendicular directions with respect to the orientation of the wood strands. We explore both graphically and statistically these "pressure-to-failures" of OSB. Also, we briefly comment on reducing sources of variability in the IB and EI of OSB.

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음향결정 구조의 레벨셋 기반 위상 및 형상 최적설계 (Level Set Based Topological Shape Optimization of Phononic Crystals)

  • 김민근;조선호;하시모토 히로시;아베 카주히사
    • 한국전산구조공학회:학술대회논문집
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    • 한국전산구조공학회 2011년도 정기 학술대회
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    • pp.693-696
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    • 2011
  • 본 논문에서는 레벨셋 방법을 이용하여, 소음을 차단하기 위한 음향 구조물의 형상 최적 설계를 수행하였다. 음향 결정 구조에서는 음향이 흩어져 있는 결정 구조에 의해서 굴절되기 때문에 결정 모양을 조정함으로써, 음향 거동을 제어 할 수 있다. 형상 최적 설계의 목적은 특정한 각도와 각속도로 입사되는 입사파에 대해서 음향 투과율(acoustic transmittance)이 최소가 되도록 음향 결정의 형상(inclusion shape)을 결정하는 것이다. 음향 압력(acoustic pressure)은 주기성을 갖는 음향 결정에 대해서 헬몰츠(Helmoltz)형태의 지배 방정식을 풀어서 얻을 수 있다. 본 연구에서는 음향 구조물로 결정이 수평 방향으로는 주기적으로 무한히 분포하고 수직방향으로는 유한한 층간 구조를 가지고 있는 소음 방어벽 (Noise barrier)을 고려한다. 결정의 위치는 고정되어 있고, 결정의 형상을 설계 변수로서 음파의 거동을 제어할 수 있도록 하였다. 주기적 구조물을 고려하기 때문에 결정의 좌와 우에 Bloch 이론을 적용해 주기적 경계조건을 부과하였고, 소음 방어벽 위와 아래에는 임피던스 행렬(impedance matrix)를 이용하여, 무한 균질 영역과 소음 방어벽사이의 음파 투과를 모사하였다. 복잡한 형상 변화를 표현하기 위해 임시적 경계를 이용한 레벨셋 방법을 사용하였다. 설계 민감도 해석을 통해 목적함수가 감소하는 방향으로 경계에서의 수직 벡터를 계산하고, 이를 헤밀턴-자코비(Hamilton-Jacob) 방정식에 대입하여, 최적의 형상을 나타내는 레벨셋 함수를 구하였다.

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Mathematical and experimental study of hydrogen sulfide concentrations in the Kahrizak landfill, Tehran, Iran

  • Asadollahfardi, Gholamreza;Mazinani, Safora;Asadi, Mohsen;Mirmohammadi, Mohsen
    • Environmental Engineering Research
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    • 제24권4호
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    • pp.572-581
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    • 2019
  • The emission of hydrogen sulfide (H2S) from the Kahrizak landfill was studied. Firstly, the field measurements were conducted in the summer and winter seasons; and the samples were analyzed using Jacob method. We predicted the H2S concentrations in the downwind using AERMOD and ISCST3. According to the AERMOD, the maximum concentration of H2S in the summer and winter were 117 ㎍/㎥ and 205 ㎍/㎥ respectively. The downwind concentrations reached zero at the distance of 35 km from the leachate treatment plant. The Geometric mean bias, Geometric variance, Fractional bias, Fraction of predictions within a factor of two of the observations and Normalized mean square error for the AERMOD were 0.58, 1.35, -0.12, 1.91 and 0.042, respectively in the summer and 1.39, 1.35, -0.05, 1.46 and 0.027 in the winter; and for the ISCST3, were 0.85, 1.03, 0.02, 1.45 and 0.04 in the summer and 1.18, 1.03, 0.15, 1.16 and 0.04 in the winter. The results of the AERMOD were compared with the ISCST3 and indicated that the AERMOD performance was more suitable than the ISCST3.

Photo-Induced Cytotoxicity of Prodigiosin Analogues

  • Park, Gyung-Se;Tomlinson, John T.;Misenheimer, Jacob A.;Kucera, Gregory L.;Manderville, Richard A.
    • Bulletin of the Korean Chemical Society
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    • 제28권1호
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    • pp.49-52
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    • 2007
  • Prodigiosin (1) is the parent member of a class of polypyrrole natural products that exhibit promising anticancer activities. They can facilitate copper-promoted oxidative DNA damage by binding to copper ions, and this activity is thought to represent their mechanism of cytotoxicity in the dark. They also possess photoinduced cytotoxicity, although 1 is too toxic in the dark to be used effectively for the treatment of cancer by photodynamic therapies. To circumvent dark toxicity by prodigiosins, the semi-synthetic analogue 2, in which the N-pyrrolic atoms of 1 are methylated to block copper coordination, and the synthetic phenyl analogues 3 and 4, which lack the copper-coordinating A-pyrrole ring of 1, were tested for their ability to inhibit colony formation of HL-60 cancer cells in the absence and presence of visible light (λ > 495 nm). Our results show that 2-4 lack cytotoxicity in the dark, but are able to inhibit colony formation of HL-60 cells following irradiation for 30 min. The synthetic derivative 4 exhibits photo-induced cytotoxicity similar to that of the natural product 1, demonstrating the potential use of prodigiosin-based compounds for treatment of cancers following irradiation with visible light.

Applying Novel Mean Residual Life Confidence Intervals

  • Guess, F.M.;Steele, J.C.;Young, T.M.;Leon, R.V.
    • International Journal of Reliability and Applications
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    • 제7권2호
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    • pp.177-186
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    • 2006
  • Typical confidence intervals for a mean or mean residual life (MRL) are centered about the mean or mean residual life. We discuss novel confidence intervals that produce statements like "we are 95% confident that the MRL function, e(t), is greater than a prespecified $\mu_o$ for all t in the interval [0, $\hat{\theta})$)" where $\hat{\theta}$ is determined from the sample data, confidence level, and $\mu_o$. Also, we can have statements like 'we are 95% confident that the MRL of population 1, namely $e_1$(t), is greater than the MRL of population 2, $e_2$(t), for all t in the interval [0, $\hat{\theta}$)" where $\hat{\theta}$ is determined from the sample data and confidence level. We illustrate these one and two sample confidence intervals on internal bonds (tensile strengths) for an important modem engineered wood product, called medium density fiberboard (MDF), used internationally.

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Exploring Reliability of Wood-Plastic Composites: Stiffness and Flexural Strengths

  • Perhac, Diane G.;Young, Timothy M.;Guess, Frank M.;Leon, Ramon V.
    • International Journal of Reliability and Applications
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    • 제8권2호
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    • pp.153-173
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    • 2007
  • Wood-plastic composites (WPC) are gaining market share in the building industry because of durability/maintenance advantages of WPC over traditional wood products and because of the removal of chromated copper arsenate (CCA) pressure-treated wood from the market. In order to ensure continued market share growth, WPC manufacturers need greater focus on reliability, quality, and cost. The reliability methods outlined in this paper can be used to improve the quality of WPC and lower manufacturing costs by reducing raw material inputs and minimizing WPC waste. Statistical methods are described for analyzing stiffness (tangent modulus of elasticity: MOE) and flexural strength (modulus of rupture: MOR) test results on sampled WPC panels. Descriptive statistics, graphs, and reliability plots from these test data are presented and interpreted. Sources of variability in the MOE and MOR of WPC are suggested. The methods outlined may directly benefit WPC manufacturers through a better understanding of strength and stiffness measures, which can lead to process improvements and, ultimately, a superior WPC product with improved reliability, thereby creating greater customer satisfaction.

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영상 인식을 위한 개선된 자가 생성 지도 학습 알고리듬에 관한 연구 (A Study on Enhanced Self-Generation Supervised Learning Algorithm for Image Recognition)

  • 김태경;김광백;백준기
    • 한국통신학회논문지
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    • 제30권2C호
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    • pp.31-40
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    • 2005
  • 오류 역전파 알고리즘의 문제점과 ART 신경회로망의 문제점을 개선하기 위해 Jacobs가 제안한 delta-bar-delta 방법과 신경회로망을 결합한 자가 생성 지도 학습 알고리듬을 제안한다. 입력층과 은닉층에서는 ART-1과 ART-2 알고리듬을 이용하고, winner-take-all 방식은 완전 연결 구조이나 연결된 가중치만을 조정하도록 채택하였다. 실험을 위해 학생증, 주민등록증, 컨테이너의 영상으로 추출한 패턴을 신경회로망의 은닉층 노드에 대해 실험하였고, 실험결과 제안된 자기 생성 지도 학습알고리듬이 지역최소화, 학습 속도, 정체 현상이 기존의 방법보다 성능이 개선된 것을 확인하였다.

강성저감을 고려한 플랫슬래브 구조물의 지진해석 (Seismic Analysis of Flat Slab Structures considering Stiffness Degradation)

  • 김현수;이승재;이동근
    • 한국지진공학회:학술대회논문집
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    • 한국지진공학회 2003년도 추계 학술발표회논문집
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    • pp.191-198
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    • 2003
  • Flat slab system has been adopted in many buildings constructed recently because of the advantage of reduced floor heights to meet the economical and architectural demands. Structural engineers commonly use the equivalent frame method(EFM) with equivalent beams proposed by Jacob S. Grossman in practical engineering for the analysis of flat slab structures. However, in many cases, when it is difficult to use the EFM, it is necessary to use a refined finite element model for an accurate analysis. But it would take significant amount of computational time and memory if the entire building structure were subdivided into a finer mesh. An efficient analytical method is proposed in this study to obtain accurate results in significantly reduced computational time. The proposed method employs super elements developed using the matrix condensation technique and fictitious beams are used in the development of super elements to enforce the compatibility at the interfaces of super elements. The stiffness degradation of flat slab system considered in the EFM was taken into account by reducing the elastic modulus of floor slabs in this study. Static and dynamic analyses of example structures were peformed and the efficiency and accuracy of the proposed method were verified by comparing the results with those of the refined finite element model and the EFM.

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