• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3477-3482
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• 2016

Background: Thyroid cancer is the most common endocrine malignancy, and exact causes remain unknown. The role of CYP450 1A1 (CYP1A1) in cancer initiation and progression has been investigated. The aim of this work was to analyze, for the first time, CYP1A1 gene expression and its relationship with several clinicopathological factors in Mexican patients diagnosed with thyroid cancer. Materials and Methods: Real-time PCR analysis was conducted on 32 sets of thyroid tumors and benign pathologies. Expression levels were tested for correlations with clinical and pathological data. All statistical analysis were performed using GraphPad Prism version 3.0 software. Results: We found that female gender was associated with thyroid cancer risk (P<0.05). A positive relationship was identified between CYP1A1 mRNA levels and the presence of chronic disease, alcohol use, tumor size, metastasis and an advanced clinical stage (P<0.05). Conclusions: The results suggest that CYP1A1 gene expression could be used as a marker for thyroid cancer.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.33 no.1
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• pp.54-61
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• 2005

Characteristics of sprays injected by gas/liquid coaxial atomizers operated at atmospheric pressure are studied using shadowgraph, mechanical patternator and PDPA. The gas-to- liquid momentum flux ratio(M) and the liquid Reynolds number(Re) are selected as key parameters in characteristics of gas/liquid coaxial sprays from the dimensional analysis. The properties of shear coaxial sprays are compared with those of swirl coaxial sprays through the macroscopic and microscopic analysis. Macroscopic similarities between shear and swirl coaxial sprays are revealed under flow conditions of high momentum flux ratio. Also, empirical correlations between the mean drop diameters(D32) and operating conditions of coaxial sprays are proposed in this paper.

• Journal of the Korea Society for Simulation
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• v.23 no.2
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• pp.17-24
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• 2014

This study attempts to show an example of developing and applying thermal hydraulic simulation model for Aircraft-EHA. The overview of research procedure is as in the following. First, The unit hydraulic simulation model, which reflects physical quantity answering engineer's purpose is developed. Second, The unit hydraulic simulation model is combined, and then branched out to EHA hydraulic model. Third, a simulation model including flow thermal is developed, and then oil temperature rise time according to 'initial temperature and load' is examined. Finally, the master graph that can be used for designing EHA combined with thermal hydraulic analysis results in several cases is compiled, and suggested. AMESim, commercial software, is used through whole procedure.

• Geomechanics and Engineering
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• v.9 no.3
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• pp.345-360
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• 2015

Wave equation analysis programs (WEAP) such as GRLWEAP and TNOWave were primarily developed for pre-driving analysis. They can also be used for post-driving measurement applications with some refinements. In the case of pre-driving analysis, the programs are used for the purpose of selecting the right equipment for a given ground condition and controlling stresses during pile driving processes. Recently, the program is increasingly used for the post-driving measurement application, where an assessment based on a variety of input parameters such as hammer, driving system and dynamic behaviour of soil is carried out. The process of this type of analysis is quite simple and it is performed by matching accurately known parameters, such as from CAPWAP analysis, to the parameters used in GRLWEAP analysis. The parameters that are refined in the typical analysis are pile stresses, hammer energy, capacity, damping and quakes. Matching of these known quantities by adjusting hammer, cushion and soil parameters in the wave equation program results in blow counts or sets and stresses for other hammer energies and capacities and cushion configuration. The result of this analysis is output on a Bearing Graph that establishes a relationship between ultimate capacity and net set per blow. A further application of this refinement method can be applied to the assessment of dynamic formulae, which are extensively used in pile capacity calculation during pile driving process. In this paper, WEAP analysis is carried out to establish the relationship between the ultimate capacities and sets using the various parameters and using this relationship to recalibrate the dynamic formula. The results of this analysis presented show that some of the shortcoming of the dynamic formula can be overcome and the results can be improved by the introduction of a correction factor.

• Journal of Institute of Control, Robotics and Systems
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• v.16 no.5
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• pp.463-468
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• 2010

An obstacle avoidance method for a mobile robot is proposed in this paper. Our research was focused on the obstacles that can be found indoors since a robot is usually used within a building. It is necessary that the robot maintain the desired direction after successfully avoiding the obstacles to achieve a good autonomous navigation performance for the specified project mission. Sensors such as laser, ultrasound, and PSD (Position Sensitive Detector) can be used to detect and analyze the obstacles. A PSD sensor was used to detect and measure the height and width of the obstacles on the floor. The PSD sensor was carefully calibrated before measuring the obstacles to achieve better accuracy. Data obtained from the repeated experiments were used to plot an error graph which was fitted to a polynomial curve. The polynomial equation was used to navigate the robot. We also obtained a direction-error model of the robot after avoiding the obstacles. The prototypes for the obstacle and direction-error were modeled using a neural network whose inputs are the obstacle height, robot speed, direction of the wheels, and the error in direction. A mobile robot operated by a notebook computer was setup and the proposed algorithm was used to navigate the robot and avoid the obstacles. The results showed that our algorithm performed very well during the experiments.

• Restorative Dentistry and Endodontics
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• v.37 no.2
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• pp.68-73
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• 2012

Objectives: The purpose of this study was to assess the accuracy of Root ZX (J. Morita Corp.) according to the location of major foramen and open apex. Materials and Methods: 81 mandibular premolars with mature apices were selected. After access preparation, 27 teeth were instrumented to simulate open apices. 54 teeth were classified according to location of major foramen under surgical microscope (${\times}16$). The file was fixed at the location of apical constriction by Root ZX using glass ionomer cement .The apical 4 mm of the apex was exposed and photo was taken and the distance from file tip to the major foramen was measured by calibrating metal ruler on graph paper. The results were statistically analyzed using ANOVA and Scheffe test at p < 0.05 level. Results: Mean distance from file tip to major foramen was 0.308 mm in Tip foramen group (I), 0.519 mm in Lateral foramen group (II) and 0.932 mm in open apex group (III). Root ZX located apical constriction accurately within ${\pm}0.5mm$ in group I of 85.71%, in group II of 59.09%, and in group III of 33.33%. There was a statistically significant difference between group I and III (p < 0.05). Conclusion: Root ZX located apical constriction accurately regardless of location of major foramen. However, Root ZX couldn't find it in open apex. Clinicians have to use a combination of methods to determine an appropriate working length at open apex. It may be more successful than relying on just electronic apex locator.

• Nuclear Engineering and Technology
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• v.53 no.6
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• pp.1769-1785
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• 2021

The Integral Pressurized Water Reactors (IPWRs) as the innovative advanced and generation-III + reactors are under study and developments in a lot of countries. This paper is aimed at the thermal hydraulic study of the hot and average fuel sub-channel in a Generation III + IPWR by loose external coupling to the neutronic simulation. The power produced in fuel pins is calculated by the neutronic simulation via MCNPX2.6 then fuel and coolant temperature changes along fuel sub-channels evaluated by computational fluid dynamic thermal hydraulic calculation through an iterative coupling. The relative power densities along the fuel pin in hot and average fuel sub-channel are calculated in sixteen equal divisions. The highest centerline temperature of the hottest and the average fuel pin are calculated as 633 K (359.85 ℃) and 596 K (322.85 ℃), respectively. The coolant enters the sub-channel with a temperature of 557.15 K (284 ℃) and leaves the hot sub-channel and the average sub-channel with a temperature of 596 K (322.85 ℃) and 579 K (305.85 ℃), respectively. It is shown that the spacer grids result in the enhancement of turbulence kinetic energy, convection heat transfer coefficient along the fuel sub-channels so that there is an increase in heat transfer coefficient about 40%. The local fuel pin temperature reduction in the place and downstream the space grids due to heat transfer coefficient enhancement is depicted via a graph through six iterations of neutronic and thermal hydraulic coupling calculations. Working in a low fuel temperature and keeping a significant gap below the melting point of fuel, make the IPWR as a safe type of generation -III + nuclear reactor.

• Nuclear Engineering and Technology
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• v.51 no.6
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• pp.1708-1714
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• 2019

The purpose of the critical evaluation of the spent fuel pool (SFP) is to verify that the maximum effective multiplication factor ($K_{eff}$) is less than the critical safety limit at 100% stored condition of the spent fuel with the maximum reactivity. At nuclear power plants, the storage standard of spent fuel, ie, the loading curve, is established to prevent criticality from being generated in SFP. Here, the loading curve refers to a graph showing the minimum discharged burnup versus the initial enrichment of spent fuel. Recently, US NRC proposed the new critical safety assessment guideline (DSS-ISG-2010-01, Revision 0) of PWR SFPs and most of utilities in US is following it. Of course, the licensed criterion of the maximum effective multiplication factor of SFP remains unchanged and it should be less than 0.95 from the 95% probability and the 95% confidence level. However, the new guideline is including the new evaluation methodologies like the application of the axial burnup profile, the validation of depletion and criticality code, and trend analysis. Among the new evaluation methodologies, the most important factor that affects $K_{eff}$ is the axial burnup profile of spent fuel. US NRC recommends to consider the axial burnup profiles presented in NUREG-6801 in criticality analysis. In this paper, criticality effect was evaluated considering three profiles, respectively: i) Axial burnup profiles presented in NUREG-6801. ii) Representative PWR axial burnup profile. iii) Uniform axial burnup profile. As the result, the case applying the axial burnup profiles presented in NUREG-6801 showed the highest $K_{eff}$ among three cases. Therefore, we need to introduce a new methodology because it can be issued if the axial burnup profiles presented in NUREG/CR-6801 are applied to the domestic nuclear power plants without any other consideration.

• Progress in Superconductivity and Cryogenics
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• v.12 no.3
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• pp.16-20
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• 2010

For large scale power applications of HTS conductor, it is getting more important to have a stacked HTS coated conductor with low loss and large current capacity. But it was not easy to measure some electric properties. Stabilizer free YBCO CC for striated/ stacked conductors is easily burned out during the measurement of the critical current density because it has no stabilizer and it is difficult to set-up the current lead and voltage taps because it has many pieces of YBCO CC in a conductor. Instead of direct measuring the critical current of a stacked HTS coated conductor, indirect estimation from measuring a magnetization loss of HTS coated conductor could be useful for practical estimation of the critical current. The magnetization loss of a superconductor is supposed to be affected by a full penetrating magnetic field, and it tends to show an inflection point at the full penetrating magnetic field when we generate the graph of magnetization loss vs. external magnetic field. The full penetrating magnetic field depends on the shape of the conductor and its critical current density, so we can estimate the effective critical current density from measuring the magnetization loss. In this paper, to prove the effectiveness of this indirect estimation of the critical current, we prepared several different kinds of YBCO CC(coated conductor) including a stacked conductor short samples and measured the magnetization losses and the critical currents of each sample by using linked pick up coils and direct voltage measurement with transport current respectively.

• Nuclear Engineering and Technology
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• v.55 no.2
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• pp.717-724
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• 2023

An essential step in evaluating and comparing the performance of two passive radiation dosimeter types, thermosluminescent (TLD) and optically stimulated luminescence (OSL), used by workers in environments with ionizing radiation for individual radiological monitoring and control of external exposure at various times (cumulative dose for 1 month), is to compare the measured dose accuracy, energy response, and coefficient of variation. In fact this performance study consists in determining the accuracy of both R(10) and R(0.07) which are considered as the ratios of the measured dose (Hp(10) or Hp(0.07)) to the delivered dose (Hp(10) or Hp(0.07)) for each photon energy. The validity of the results of this test is based on the acceptance limits of the ICRP and the international standard IEC-62387. The relative energy response used is normalized to the ¹³⁷Cs 662 keV energy to find which energy response is closest to the ideal case, and the coefficient of variation that allows to determine the statistical fluctuation of the Hp(10) and Hp(0.07) doses. The results of the accuracy test for the OSL and TLD dosimeters are acceptable because they fall within the ICRP limits. For the energy response, the OSL performs better than the TLD for Hp(10) and Hp(0.07), and for the coefficient of variation, the OSL satisfies the requirements of ISO 62387 for both Hp(10) and Hp(0.07), while the TLD satisfies these requirements only for the measurement of Hp (0.07).