• The Journal of Korean Physical Therapy
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• v.21 no.3
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• pp.17-24
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• 2009

Purpose: The purpose of this study was to investigate the effects of a combination of isotonic (CI) technique on the balance, muscle fatigue and muscle activities of the quadriceps muscle in the paretic leg of hemiplegic patients. Method: All the subjects received a combined isotonic technique of proprioceptive neuromuscular facilitation (PNF) for about 30 minutes 3 times per week for 6 weeks. The root mean square (RMS) and mid frequency (MF) were recorded by surface electromyography (EMG)(EMG/EP system, OXFORD Medelec, UK) during maximal voluntary isometric contractions (MVIC). The balance ability was measured by a balance system (BIODEX, USA). Result: The RMS of the quadriceps muscle at post-treatment was significantly increased compared to that at pretreatment (p<0.05). Yet there was no significant difference among the three muscles. There were no significant difference in the MF of the vastus lateralis and rectus femoris between pre- and post-treatment, but the MF of the vastus medialis was significantly decreased (p<0.05). There was a significant difference in the vastus medialis and lateralis between pre- and post-treatment (p<0.05). Moreover, the overall stability index at post-treatment was significantly decreased compared to that at pre-treatment (p<0.05). But there was no significant difference between the anterior/posterior and medial/lateral stability indexes. Conclusion: The results of this study indicated that a CI technique of PNF had an effect to improve the balance and muscle activity in hemiplegic patients.

• Korean Journal of Clinical Laboratory Science
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• v.36 no.2
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• pp.127-130
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• 2004

Analytical sensitivity on TDM test is the lowest concentration that can be distinguished from background noise. The aim of study was to evaluate analytical sensitivity that is also referred to as the lower limit of detection(LLD) about difference between zero calibrator and isotonic saline sample. We tested for 10 days with zero calibrators and 0.85% saline samples while running trilevel control samples under control. Raw data divided by two groups calculated mean and standard deviation from two sample populations and analytical sensitivity by ${\bar{X}}+2SD$. In comparison with isotonic saline samples and zero calibrators, there were significant differences in phenytoin, phenobarbital and vancomycin, etc. Especially analytical sensitivity on phenytoin is at the same level as the upper limit of analytical measurement range with $40{\mu}g/mL$. We think the cause of this is matrix interference. In conclusion, we were sure that standard protocol for analytical sensitivity as lower limit of analytical measurement range on TDM test must be measured with zero standard rather than an isotonic saline sample and type 1 reagent DW for reducing matrix effects within interactions between different materials in a mixture.

• PNF and Movement
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• v.5 no.2
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• pp.37-46
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• 2007

Purpose : The purpose of this study was to examine the effects of combination of isotonic and rhythmic stabilization in proprioceptive neuromuscular facilitation on trunk stability and balance in elderly people with chronic low back pain. Subjects : Thirty-two elderly people ($73.78{\pm}8.49$ years of age) who had complaints of CLBP were randomly assigned to 2 groups: experimental group and control group. Methods : Subject trained with combination of isotonic and rhythmic stabilization in proprioceptive neuromuscular facilitation for 4weeks with aim of improving trunk stability and balance. Weight distribution, trunk muscle balance, static balance ability and dynamic balance ability were measured before, at the end of training. Results : Data were analyzed using two-way ANOVA. After the exercise programs, there were significant differences in the weight distribution, trunk muscle balance and dynamic balance ability between the experimental and control group. However there was no significant difference in the one leg stance test(p<.05). Conclusion : This study suggest that PNF programs may be appropriate for improving trunk stability and balance in elderly people with CLBP.

• Journal of the Korean Society of Food Science and Nutrition
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• v.31 no.3
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• pp.399-404
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• 2002

The fermented fruit and vegetable mixed broth was prepared by using bacteriocin-producing lactic acid bacteria to evaluate the possibility of developing isotonic beverage with anticariogenic activity. Optimum conditions were also established to produce bacteriocin by a mixed culture system consisting of Lc. lactis and Leu. mesenteroides in a fruit and vegetable mixture. Production of bacteriocin was not observed when both strains were simultaneously innoculated, but pH adjustment of the broth fermented by Leu. mesenteroides to nearneutral pH stimulated the production of bacteriocin by Lc. lactis. The concentration of sodium of the fermented broth was higher than those of commercial products. Color change of the fermented broth was not observed during storage. The fermented broth showed strong inhibitory effect against Streptococcus mutans which is an oral inhabitant with a cariogenic activity. Bacteriocin activity in the fermented broth was retained very stable for 4 weeks at 4$\^{C}$. The results indicated that bacteriocin-producing lactic acid bacteria can be used for the preparation of a Korean style thirst-quenching beverage containing bacteriocin.

• PNF and Movement
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• v.16 no.3
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• pp.333-343
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• 2018

Purpose: The purpose of this study was to investigate the effects of a neck exercise using a proprioceptive neuromuscular facilitation (PNF) neck flexion and extension pattern on body balance in a progressive range of positions (supine, prone on elbow, and sitting), on numbness in the upper extremities, and on neck flexion motions in cervical myelopathy patients. Methods: One participant who was diagnosed with cervical myelopathy participated in this study. A reversal design (A-B-A') was used. The A and A' were the baseline period (no intervention), and B was the intervention period. The intervention used a neck extension pattern with a hold-relax technique and a neck flexion pattern with a combination of isotonic techniques in the supine position. Then, neck flexion and extension patterns were applied together with a reversal technique for stabilization, followed by a neck extension pattern with a combination of isotonic techniques in the prone position on the elbows. Finally, a neck flexion and extension pattern was used with a stabilizing reversal technique, and a neck extension pattern was applied with a combination of isotonic techniques in the sitting position for 60 minutes per day, 3 times per week for 8 weeks. To measure balance, numbness, and neck motion during neck flexion, the one-leg stand test and the visual analogue scale were used. Results: The right and left one-leg stand tests showed increased balance ability in the intervention phase. Upper extremity numbness was decreased in the intervention phase, and neck flexion motion was increased in the intervention phase. These increases were maintained after the intervention (Baseline II). Conclusion: These results suggest that a neck exercise using a PNF neck pattern with additional techniques in a progressive range of positions has a positive effect on cervical myelopathy patients for balance, numbness, and neck motion.

• Korean Journal of Veterinary Research
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• v.36 no.2
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• pp.305-312
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• 1996

Cell volume regulatory mechanisms are usually disclosed by exposure of cell to anisotonic media. If a cell is suddenly exposed to hypotonic media, it swells initially like an osmometer but within minutes regains its original cell volume. This behavior has been labelled as regulatory cell volume decrease(RVD). RVD is believed to result from the loss of permeable ions through the membrane. In this study, we examined hypotonically induced changes in the membrance currents involved in RVD by using whole cell voltage clamp technique in the unfertilized hamster egg. At -40mV of the holding potential, the stationary current was maintained in the hamster egg exposed to isotonic solution composed of, mainly, 115mM NaCl and 40mM mannitol. Hypotonic solution was prepared by removing mannitol. Therefore, the concentrations of $Na^+$ and $Cl^-$ in this hypotonic media were the same as those in the isotonic solution. Following 30 to 60 sec after applying the hypotonic media to the egg, the inward current was evoked. This inward current was eliminated by $100{\mu}M$ 4-acetamido-4'-isothiocyanostil-bene-2,2'-disulfonic acid(SITS), an anion channel blocker, leaving the small outward current component. Further addition of 2mM $Ba^{2+}$, a broad $K^+$ channel blocker, completely abolished the small outward current left even in the presence of SITS during hypotonic stress. These results suggest that $K^+$ and $Cl^-$ move out of cells, resulting in RVD. To test the involvement of $Na^+$ in RVD, 20mM Na-isethionate was substituted for mannitol in isotonic media(135mM $Na^+$) and Na-isethionate (20mM) was freed the hypotonic solution. Only $Cl^-$ concentration in both isotonic and hypotonic media was kept constant at 115mM, whereas concentration of $Na^+$ was lowered in hypotonic solution to 115mM from 135mM in isotonic solution. Hypotonic medium induced the outward current in the egg equilibrated isotonically. This current was reduced by $100{\mu}M$ SITS but was augmented by 2 mM $Ba^{2+}$. In terms of RVD, these results imply that $Cl^-$ efflux is coupled with $K^+$, maybe for electroneutrality during hypotonic stress and/or with $Na^+$ via unknown transport mechanism(s). From the overall results, the hypotonic stress facilitates the movement of $Cl^-$ and $K^+$ out of the hamster egg to regain cellular volume with electroneutrality. If there exist a difference in $[Na^+]_0$ between isotonic and hypotonic solution, another transport mechanism concerned with $Na^+$ may, at least partly, participate in regulatory volume decrease.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.13 no.3
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• pp.212-218
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• 2020

When Radiofrequency energy is applied to the human body, the vibration width is very short. Therefore, the electrolyte burn generated when using the direct current does not occur. Ion molecules, polarized molecules, etc., vibrate more than 40,000 times per second, converting them into frictional heat to generate deep heat. The blood flow of capillaries increases 4-5 times more than at rest, increasing the supply of oxygen, nutrients, antibodies, and white blood cells. In addition, the electrochemical reaction does not occur because the vibration width and the pulsation period are very short. It is a physical factor treatment method that does not stimulate the sensory nerves and motor nerves. In this study, an isotonic exercise is performed in a young normal adult using a Radiofrequency pain treatment device. The purpose of this study is to integrate rehabilitation therapy by measuring electromyography data during isotonic exercise and confirming the effect on changes in motor neuron response. The EMG data generated when isotonic exercise of the forearm biceps muscle and the EMG data measured after the use of a Radiofrequency pain treatment device after exercise were RMS, respectively, and verified through t-test. It was confirmed that there was a significant difference in both men and women because the t-value was smaller than the significance level p (<.05).

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.8 no.2
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• pp.178-186
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• 2015

Endurance time is very important indicator to estimate muscle fatigue. In the case of measuring endurance time directly, it is dangerous for subject to perform a test until the point of failure to main time force. Therefore, this paper presents the model to estimate endirance time using indirect measurements such as personal factors and anthropometrical data. Previous studies had shown that personal factors such as gender and age were not related to endurance time, but recently studies have shown that it is estimated by using independent variable or predictor such as GTA (Gravitational Torque of the horizontal, stretched arm) and MVC (Maximum Voluntary Contraction). The present study investigated variables to estimate endurance time using personal factors and anthrometrical data during isotonic contractions. Twenty five healthy subject volunteered for this study, and performed three test sessions of isotonic contraction exercises at 10~50% respectively. Afterward the correlation coefficient and p-values were compared among regression models using personal factors and anthropometrical data. The results demonstrated that multi-regression model had significant coefficient of correlation, and was useful estimate endurance time.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2012.05a
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• pp.751-752
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• 2012

• Journal of the Korean Statistical Society
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• v.25 no.3
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• pp.381-391
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• 1996

In the analysis of contingency table with ordered categories, the relationship between odds for adjacent categories has received con-siderable interest. We consider likelihood ratio tests of independence against an order restriction on odds in 2 $\times$ k contingency tables.