• Title/Summary/Keyword: Irritation

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Preparation of blocking ultraviolet mica composites using Nano-TiO2 (Nano-TiO2를 이용한 자외선차단 마이카 복합체 제조)

  • Yun, Ki Hoon;Lee, Jaebok;Moon, Young-Jin;Go, Hee Kyoung;Lee, Yi;Lee, Dong-Kyu
    • Journal of the Korean Applied Science and Technology
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    • v.35 no.4
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    • pp.1197-1205
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    • 2018
  • UV protection cosmetics belong to functional cosmetics and contain organic or inorganic UV blocking pigments. The inorganic UV blocking pigments are mainly zinc oxide and titanium dioxide. It is known that inorganic UV blocking pigment has a diameter of 60 to 100 nm and has good blocking ability of UVA and UVB. Also, it has high inactivity against sunlight including UV and is excellent in safety. In addition, it is not absorbed or accumulated on the skin like organic pigments and does not cause skin irritation or allergy. In this study, mica, a plate-shaped inorganic pigment, nanosized titanium dioxide, an UV blocking material, and hydrophobic silica were surface-treated with surfactants. And then, titanium dioxide nanoparticles and silica were physically adsorbed on the mica by non-chemical mutual attraction due to differences in charge. Thereafter, the mica complex was surface-treated with silane to prepare a hydrophobic UV blocking pigment complex. The plate-shaped UV blocking composite improves the cohesiveness of a general nanoparticle material titanium dioxide, enhances UV blocking effect due to uniform dispersion, and can greatly improve dispersion stability in cosmetic formulations by surface treatment with hydrophobic property. The surface charge of the pigment was evaluated by zeta potential. The properties of the UV blocking pigment complex were evaluated by FE-SEM, XRD, FT-IR and UV-VIS.

An Analysis of the Trends of Aromatherapy Researches in Chinese Literatures

  • Sun, Jiao-Jing;Kim, Kyeong-Ran
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.1
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    • pp.239-251
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    • 2021
  • Traditional Chinese medicine has treated diseases and improved health in nature-based experience. Advanced nations began to be interested in naturopathic therapy in the late 19th century and it led China to research aromatherapy. This study searched previous researches related with aromatherapy and generally analyzed aroma oil, applied body parts, methods of use, and period of use. For research contents, scientific and society journals from 2000 to 2019 related with aromatherapy were searched in CNKI(www.cnki.com) and WANFANG DATE(www.wanfang.com). Finally, 30 papers were selected through 5-step qualitative evaluation and expert review and analyzed. Frequency and percentage(%) were calculated by means of the Excel 2013 Program and represented by a chart. The results of analyzing aromatherapy trends are as follows. All 30 papers were researched in the medical society. The most common symptom was irritation and anxiety that appeared in 13 papers. Lavender oil and bergamot oil were commonly used aroma oil. Commonly applied part and method were nose and nasal inhalation. For aroma oil associated with symptoms, lavender oil was the best in irritative, anxious, and negative emotion, depression, labor pain, sleep disorder, migraine, tension, and vomiting, pain, and fatigue after operation. Lemon, ginger, and peppermint oil was good for nausea. Based on the findings, this study derived applied body parts, methods of use, and period of use in aromatherapy. However, most aromatherapy was used for patients in the nursing and medical fields in the simple form of inhalation and local massage. This study will suggest a standard ground that aromatherapy is good for pain, colic pain, and tension in a short period but needs a long period for the efficacy of psychological and neurological symptoms.

A Basic Study for Development of the Korean Anger Provoking Situation Scale for Youth (한국판 청소년 분노유발상황 척도 개발을 위한 기초연구)

  • You, Dong-Hwan;Kim, Min;Lee, Jee-Sook
    • The Journal of the Korea Contents Association
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    • v.21 no.4
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    • pp.520-532
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    • 2021
  • The purpose of this study is to provide basic data for the development of the anger provoking situation scale using the mixed research method. For this purpose, three research methods were used: content analysis of domestic and international anger-inducing situation scale, NAS-PI factor and reliability analysis of youth anger-provoking scale, and FGI with youth expert. In the results of NAS-PI, there were four categories of 'unrespectful treatment', 'unfairness', 'annoying traits of others', and 'irritation' except 'frustration' among five categories. The results of the FGI consisted of seven categories: 'rejection', 'physical and verbal violence', 'ignorance', 'frustration', 'control and restraint', 'rumination', and 'interpersonal relationship'. As a result of integrating these contents, it is finally possible to reconstruction in to seven categories such as 'unfairness', 'injustice', 'ignorance', 'control and restraint', 'ignorance', 'frustration' 'interpersonal relationship'. The meaning of this study is to provide the basic data for the development of the anger provoking situation scale for domestic adolescents by integrating the contents analysis and quantitative and qualitative researches of domestic and international anger provoking situation scale. The results of this study are as follows. First, it is necessary to study the anger provoking situations reflecting sociocultural context, and to develop the reliability and validity of the anger provoking situation scale.

Biochemical properties and gluten degradation of Lactobacillus paracasei strain GLU70 isolated from salted seafood (젓갈에서 분리한 락토바실러스 파라카제이 GLU70 균주의 생화학적 특성 및 글루텐 분해능)

  • Park, Hyein;Yoon, Seul Gi;Jang, Junho;Byun, Ji Young;Yoon, Bok Kun
    • Korean Journal of Food Science and Technology
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    • v.54 no.2
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    • pp.203-208
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    • 2022
  • Gluten is an insoluble protein present in cereals such as wheat. Gluten consumed through food is not digested and accumulates in the body; this has been linked to digestive discomfort, irritation, and various digestive disorders, including intestinal inflammation. In this study, the Lactobacillus paracasei strain GLU70, which exhibits a glutendegrading ability, was isolated from salted seafood. At a pH of 3.0, GLU70 showed a survival rate of approximately 84%, and at 0.3% oxgall, it showed a survival rate of approximately 53%. When the culture supernatant collected after 12 h of incubation was added to flour dough, approximately 50% gluten degradation was observed. Moreover, among several probiotic isolates exhibiting proteolytic activity selected to assess the gluten-degrading ability, GLU70 showed superior results regardless of the dough fermentation temperature. Although further research is required, GLU70 is expected to be of value in manufacturing gluten-reduced products and the food industry as an ingredient or additive.

The Effect of Pan Play Counseling in the Midst of COVID-19 on the Reduction of Anxiety in College Students (COVID-19 상황에 판놀이 상담이 대학생의 불안 감소에 미치는 효과)

  • Kim, Kyung Hee
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.2
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    • pp.317-324
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    • 2021
  • The purpose of this study was to conduct pan play counseling that contains Korean cultural characteristics to see if it affects college students' anxiety reduction in coronavirus situations. Counseling was conducted for 40 minutes once a week. The associations of participants were recorded for each session. The score of anxiety test decreased in the participants' pre-and post-anxiety tests. The effectiveness of pan play counseling was verified. Case analysis applied phenomenological research method. Structural decisions through case analysis were in the order of regression, expression, differentiation, and integration. In the results of case analysis, participants feel confused through encounters in the early stages and regress unconsciously. Emotions of negativity that could not be erupted in the expression structure appear as consciousness, and the participants awaken. Participants expressed emotions such as fear, anxiety, loneliness, anger, and irritation. Consciousness of the unconscious causes a transformation of ego. The ego gains discernment as the great drama emerges from the differentiated structure. In other words, it builds confidence. The goal of counseling is to reinforce the ego, realizing the potential to overcome anxiety. In the last integration's structure, a wedding, a baby, and a old wise man appeared, showing that a transformation took place. In the results of this study, it was verified that pan play counseling has a healing effect. This study is expected to serve as an opportunity to develop Korean counseling techniques that incorporate Korean culture.

A Study on Inflammation and Itching of Cyperus rotundus Ethyl Acetate Fractions (향부자 에틸아세테이트 분획물의 염증 및 가려움증에 관한 연구)

  • Do Gyu, Kim;Ji Yeon, Lee;Sohyun, Mun;Yukyung, Kim;Nari, Kim;Ah Reum, Jung;Jun-Hwan, Jang;Jae-Soeb, Lee;Sang Bae, Han;Jun-Tae, Bae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.48 no.4
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    • pp.303-312
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    • 2022
  • In this study, Cyperus rotundus (C. rotundus) was fractionated into ethyl acetate to identify α-cyperone, a representative indicator, and its ethyl acetate fraction were evaluated to confirm the possibilityas a functional cosmetic ingredient. As a result of HPLC analysis, it was confirmed that the content of α-cyperone was 5.243%. In order to verify the inflammatory relief effect of the ethyl acetate fraction from C. rotundus (EAFC) and α-cyperone, it was confirmed that nitric oxide (NO) production inhibitory ability in RAW 264.7 macrophages induced an inflammatory reaction with lipopolysaccharide (LPS). Real-time qPCR analysis confirmed inhibition of mRNA expression level of inflammatory factors, IL-1β, IL-6, TNF-α, COX-2 and iNOS. As a results of conducting a clinical study using a simple cosmetic formulation containing EAFC, it was confirmed that the skin irritation stimulated by sodium lauryl sulfate (SLS) was calming and relieving itching. Through these results, it is believed that the C. rotundus can be used as a natural cosmetic ingredient that has the effect of inhibiting inflammation and relieving itching.

Study on Stabilization of Retinaldehyde using Drug-in-Cyclodextrinin-Liposome (DCL) for Skin Wrinkle Improvement (레틴알 안정화를 위한 사이클로덱스트린-리포좀에 관한 연구)

  • Ha, Ji Hoon;Choi, Hyeong;Hong, In Ki;Han, Sang-Kuen;Bin, Bum Ho
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.48 no.1
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    • pp.77-85
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    • 2022
  • Retinaldehyde (RA), vitamin A derivative, is an intermediate between retinol and retinoic acid and has an excellent wrinkle improving effect. In this study, Drug-in-cyclodextrin-in-liposome (DCL) was used to enhance the stability and skin penetration of RA. The complex of RA and hydroxypropyl-beta-cyclodextrin (HP-β-CD) was prepared by the freeze-drying method, and the presence or absence of inclusion of retinal was confirmed by UV-Vis spectrometer, FT-IR and SEM images. RA was captured in HP-β-CD about 95.6% on 1 : 15 (w/w). The retinal-HP-β-CD complex was encapsulated in liposomes using a homomixer and microfluidizer, with an average particle size of 215 ± 4.2 nm and a zeta potential of -31.2 ± 0.5 mv. In the evaluation of the degradation stability of RA, degradation rate of RA-HP-β-CD-liposomes in water was 1.8% higher than RA-liposome (5.8%), RA-HP-β-CD complex (9.7%) and RA alone (37.6%). RA cream (0.05% RA) including RA-HP-β-CD-liposomes was prepared for clinical test with wrinkle-improving efficacy and skin dermis denseness evaluated for 2 or 4 weeks. RA cream showed a significant wrinkle improving effect without skin irritation. In conclusion, it was confirmed that the double stabilization technology using the DCL system contribu tes to the effect of improving skin wrinkles by increasing the stabilization of retinal.

A case of distichiasis treatment using electroepilation in a dog (개에서 전기제모술을 이용한 첩모중생의 치료 1례)

  • Myeong-Gon, Kang;Dong-Hyun, Han;Sei-Myoung, Han;Eun-Gyeom, Jung;Gyeong-Min, Kim;Shin-Ho, Lee;Yoon-Joo, Shin;Ju-Bin, Kang;Dong-Bin, Lee;Phil-Ok, Koh;Jae-Hyeon, Cho;Chung-Kil, Won;Chung-Hui, Kim
    • Korean Journal of Veterinary Service
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    • v.45 no.4
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    • pp.325-330
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    • 2022
  • Distichiasis is one of the diseases commonly encountered in companion animals, and these abnormal eyelashes cause corneal ulcers, continuous eye irritation, eye pain, glare, epiphora, foreign body sensation and can cause corneal opacity and vision loss in severe cases. In this study, an eyelash epilation needle for animals was developed and applied to a real case, and the results were observed. In a case of corneal ulcer caused by distichiasis of a 2-year-old Shih Tzu, a high-frequency surgical instrument for animals was converted into an electric epilation needle to attempt a procedure to destroy the eyelash hair follicles on the upper eyelid. A epilation needle was developed to have a diameter of 0.1 mm and a length of 4 mm at the end of the handle of DOCTANZ 400, an electrosurgical instrument for animals only. In the procedure, 2~3 mm of an epilation needle was inserted into the hair follicle, and 1 watt of electric power was applied to the hair follicle for about 5 sec. to carry out electrolysis until white bubbles were generated around the meibomian glands thereby destroying the hair follicle. As a result, no eyelashes grew any longer in the treated area indicating that the treatment was successful. It is hoped that the method developed in this study will be applied so that it will be widely used as a treatment method for distichiasis in companion animals that can be frequently seen hereafter.

Interfacial Properties of Propylene Oxide Adducted Sodium Laureth Sulfate Anionic Surfactant (프로필렌 옥사이드를 부가한 소듐 라우레스 설페이트 음이온 계면활성제의 계면 특성에 관한 연구)

  • Jeong Min Lee;Ki Ho Park;Hee Dong Shin;Woo Jin Jeong;Jong Choo Lim
    • Applied Chemistry for Engineering
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    • v.34 no.3
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    • pp.264-271
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    • 2023
  • In this study, ASCO SLES-430 surfactant was synthesized by adducting 3 moles of ethylene oxide and 1 mole of propylene oxide to lauryl alcohol followed by a sulfation process, and the structure of the synthesized ASCO SLES-430 was elucidated by performing FT-IR, 1H-NMR and 13C-NMR analyses. Interfacial properties such as critical micelle concentration, static surface tension, emulsification index, and contact angle were measured, and environmental compatibility indices such as oral toxicity and skin irritation were also estimated for ASCO SLES-430. Both results were compared with ASCO SLES-226 and ASCO SLES-328 SLES surfactants possessing 2 moles and 3 moles of ethylene oxide, respectively. In particular, both foaming ability and foam stability were evaluated for ASCO SLES-430 and compared with ASCO SLES-226 and ASCO SLES-328, which have been widely used in detergent products, in order to test the potential applicability of ASCO SLES-430 in detergent product formulation for a small capacity built-in washing machine.

The study on Coal Spontaneous Ignition Prevention using Safety Materials of Food and Cosmetics (식품과 화장품의 안전 소재를 이용한 석탄 자연발화 억제에 대한 연구)

  • Jun, Soo-Man;Kim, Young-Hee
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.2
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    • pp.368-376
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    • 2022
  • Spontaneous ignition occurs in industrial sites or anywhere in our lives, and is a phenomenon in which a substance ignites itself without an ignition source in the atmosphere. As the rate of chemical reaction increases, the heat generated increases, and the risk of spontaneous ignition increases. In this study, safe raw materials used for food and cosmetics were mixed to prepare coal spontaneous ignition prevention agents specifically among various spontaneous ignition phenomena. The effect of suppressing spontaneous combustion of coal was confirmed through lab and field tests with low-calorie, low-grade coal from Indonesia. As a result of the outdoor field test, the ignition prevention agent manufactured in this study compared with the control group(Fire after 90 days) showed excellent ignition inhibitors for more than 120 days. In addition, CO concentration control was confirmed by comparing the concentration of carbon monoxide for 50 days at the indoor coal yard. It was confirmed that the results were better than the comparative group coal and the existing anti-firing method. In addition, the possibility of coal fire prevention agents for indoor coal farms will be applied from 2024 was confirmed by studying the environment and safety of workers' working environments through official test such as soil and water quality test, MSDS of coal fire prevention agents in consideration of working workers, water quality, and eye irritation tests.