• Title/Summary/Keyword: Iron saturation

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Altered Biodistribution of Gallium-67 in a Patient with Multiple Factors Influencing Iron-transport Protein Saturation (철운반단백질 포화정도에 따른 Gallium-67 체내분포의 변화: 증례보고)

  • Choi, Joon Young;Kim, Sang Eun;Lee, Kyung Han;Kim, Byung-Tae
    • The Korean Journal of Nuclear Medicine
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    • v.32 no.1
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    • pp.114-119
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    • 1998
  • We present a case of a young female patient with fulminant hepatitis who showed an altered biodistribution of Ga-67, after being scanned twice at 10 month intervals. On initial scan, uplake of Ga-67 was increased in the liver, kidneys, and skeletons. Increased hepatic Ga-67 uptake may be explained by increased transferrin unbound Ga-67 that was taken up by the inflamed liver. The saturation of iron-binding proteins due to multiple transfusions may lead to increased renal and skeletal Ga-67 uptake. On follow-up scan hepatic Ga-67 uptake was markedly increased. Also increased Ga-67 uptake in the axial skeleton and normalized renal uptake were shown. The findings were consistent with iron deficiency anemia. This case demonstrates altered Ga-67 biodistribution associated with multiple transfusions, fulminant hepatitis, and iron deficiency anemia.

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Anemia of Chronic Liver Diseases (만성(慢性) 간질환(肝疾患)의 빈혈상(貧血像))

  • Shin, Hyun-Chung;Lee, Jhung-Sang;Koh, Chang-Soon;Lee, Mun-Ho
    • The Korean Journal of Nuclear Medicine
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    • v.5 no.2
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    • pp.41-56
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    • 1971
  • The pathogenetic mechanisms of anemia in patients with chronic liver disease were observed. Seventeen patients with moderate to advanced hepatic diseass were studied by various methods. Only patients without previous blood loss were included: 14 had cirrhosis, 2 had active chronic hepatitis, and one had inferior vena cava obstruction with associated liver cirrhosis. The followings were the results: 1. The anemia based on red blood cell count, Hb., and Ht. was found in 76.5-78.6% of the patients. 2. Red cell indices indicated that normo-macrocytic and normochromic anemia was present is the majority of the patients. 3. No evidence of megaloblastic anemia was found on the basis of the morphological examinations. 4. Serum iron, TIBC, % saturation and iron content in the bone marrow indicated that iron deficiency anemia was present in about half of the patients. 5. In the view of the erythrocyte dynamics, primary increase in the red cell destruction was ascribed to the cause of the anemia. 6. Decrease in the red cell survival time was not correlated with MCV, % saturation and S.L. ratio. Also, hemoglobin level was not correlated with MCV, % saturation and $T_{50}Cr$. Therefore, multiple causes may be involved in the pathogenesis of the anemia. 7. Anemia as determined by the red cell volume was found in only 60% of the patients. It may be possible that hemodilutional anemia is present.

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Physical Performance in Young Women with Depleted Iron Stoles (젊은 여성의 철분저장 고갈상태와 운동수행능력)

  • 정영진;정명일;정종귀
    • Journal of Nutrition and Health
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    • v.35 no.2
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    • pp.223-228
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    • 2002
  • The purpose of this study was to investigate the relationship between iron deficiency without anemia and physical performance in healthy women aged 20-21 yrs. Ten subjects with normal iron stores (serum ferritin $\geq$ 12$\mu\textrm{g}$/L: iron-sufficient group) and 11 subjects with iron depletion without anemia (serum ferritin < 12 $\mu\textrm{g}$/L and serum hemoglobin > 120 g/L: iron-depleted group) were chosen from a group of 50 women and were given physical-performance tests, including determinations of maximum oxygen consumption (VO$_2$ max) and ventilatory threshold. Iron status assessment included determination of hemoglobin, hematocrit, seam ferritin, total iron-binding rapacity, serum iron and transferrin saturation values. Dietary iron intake was assessed based on seven-day food intake records written by the subjects. Physical activity level was estimated by frequency questionnaires and two-week physical activity records were compiled daily by the subjects. Blood ferritin concentration was significantly lower in the iron-depleted group than in the iron-sufficient group (p < 0.05). However, other variables showing iron status was not different between the groups. There were no significant differences in body size, body composition and physical activity levels between the groups. Daily dietary iron, total protein and animal protein intakes of the iron-sufficient group were significantly higher than those of the iron depleted group. However, no differences were found in the amount of dietary vitamin C and fiber between the groups. The values for VO$_2$max and VO$_2$max corrected with weight or fat-free mass were not different between the groups. However, the ventilatory threshold was significantly higher in the iron sufficient group than in the iron-depleted group. The lower ventilatory threshold in the iron-depleted group suggests that iron depletion without anemia could diminish aerobic physical performance in young women. In addition, a significant correlation of physical performance to serum fferritin level was shown only in the iron depleted group.

Effects of Nutritional Education and Iron Supplementation on Iron Nutrition and Anemia of Middle School Girls

  • Hong, Soon-Myung;Hwang, Hye-Jin
    • Preventive Nutrition and Food Science
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    • v.8 no.4
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    • pp.406-411
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    • 2003
  • The objective of this study was to investigate the effects of iron supplementation and nutrition education on the iron status and anemia of middle school girls in Ulsan city in Korea. The subjects were already diagnosed as having anemia (hemoglobin < 12 g/dL) or iron deficiency (ferritin < 12 ng/mL and/or transferrin sataturation < 14 %). Over a period of three months, one iron tablet (80 mg Fe as ferrous sulfate/day) was administered to the iron deficient subjects and two tablets (160 mg Fe as ferrous sulfate/day) were administered to the anemia subjects. Total calorie intake of subjects was 82.1 % of RDA. The iron intake of subjects was 91.3 % of RDA and the Ca intake was 78.8 % of RDA. The basal hemoglobin concentration of subjects averaged 12.8 1.2 g/dL, and this increased significantly (p < 0.001) to 13.2 0.9 g/dL after iron supplementation. The basal ferritin concentrations were 14.9 14.2 ng/mL and these significantly increased to 26.6 19.8 ng/mL (p < 0.001). The level of total iron binding protein (TIBC) significantly decreased from the initial 523.1 108.7 $\mu\textrm{g}$/dL to 462.2 90.2 $\mu\textrm{g}$/dL (p < 0.001) after iron supplementation. Anemia symptoms such as‘Being bruised easily’, ‘Inflamed inner mouth’, and ‘Pale face’ improved significantly after iron supplementation in the subjects. There was a negative correlation between their class & year ranking and serum iron level, transferrin saturation after nutritional education and iron supplementation. It was shown, therefore, that the higher the improvement of their anemia level after iron supplementation, the higher their academic performance. It was shown that there was some improvement of their dietary attitudes after nutritional education, and that their serum level related to anemia symptoms and iron nutrition was improved after iron supplementation.

A Study on Iron Nutritional Status of Girls at Puberty in Kangnung Area (강릉지역 일부 사춘기 소녀의 철분 영양상태에 관한 연구)

  • 김은경;류옥남;박계월
    • Korean Journal of Community Nutrition
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    • v.4 no.2
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    • pp.139-148
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    • 1999
  • This study was designed to assess the iron nutritional status of girls at puberty in Kangnung area. The subjects consisted of 161 adolescents in sixth-grade in primary school and first-grade in middle school girls. Anthropometric measurements were taken for body weight, height, percentage of body fat, and circumferences of waist and hip. Nutrient intakes were assessed by modified 24-hour recall method. Food models and other measuring tools were also used. Fasting blood samples were obtained and analyzed for hemoglobin(Hb) concentration, hematocrit(Hct), serum iron(FE) and total iron binding capacity(TIBC). Mean values for Hb, Hct, Fe, TIBC, TS and serum ferritin were $13.6{\pm}0.9g/dl$, $39.6{\pm}3.9%, 91.3{\pm}36.3{\mu}g/dl$, $327.9{\pm}45.2{\mu}g/dl$, $28.3{\pm}11.8%$ and $37.4{\pm}24.2ng/ml$, respectively. Prevalence of iron deficiency greatly varied by indices from 4.8% when judged by Hb to 18.4% by serum Fe concentration. The Hb concentration was positively correlated with Hct(r=0.641), serum iron(r=0.266) and transferrin saturation(r=0.237)(p<0.05). On the other hand, serum ferritin concentration showed significantly negative correlation with TIBC(r=-0.572). Mean daily intake of iron was 14.94mg and heme iron intake was 1.13mg and which was 7.6% of total iron intake. Total absorbable iron calculated by the method of Mosen was 1.38mg and bioavailability of dietary iron was 9.3%. These results suggest that the prevalence of iron deficiency of pubertal girls is very high, therefore the guidelines for diet and social supports, such as, school food service system should be provided to improve their iron status in middle school students.

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Iron Status in Female College Students in the Gyeongnam Area (경남 일부지역 여대생의 철 영양상태에 관한 연구)

  • Park, Mi-Young;Kim, Sung-Hee
    • Journal of Nutrition and Health
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    • v.44 no.3
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    • pp.222-230
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    • 2011
  • This study was undertaken to investigate iron status and related factors in female college students residing in Gyeongnam. The subjects were divided into normal (40.8%) and iron deficiency (ID) groups (59.2%) by iron status. Mean height, weight, lean body mass, percent body fat, body mass index, and wrist to hip ratio were not significantly different between the groups, but basic metabolic rate was significantly higher in the normal group than that in the ID group. The levels of hemoglobin, hematocrit, serum ferritin, transferrin saturation, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration were significantly higher in the normal group than those in the ID group. However, total iron binding capacity was significantly lower in the normal group than that in the ID group. Daily intake of protein, heme-Fe, niacin, and vitamin C were significantly higher in the normal group than those in the ID group. The mean intake of protein, Fe, niacin, vitamin $B_{12}$, and vitamin C based on the Korean recommended intake (RI) were significantly higher in the normal group than those in the ID group. The mean intakes of Ca, vitamin $B_{12}$, and folate in both groups were < 75% of the Korean RI. In conclusion, increasing dietary heme-Fe and vitamin C may be helpful for preventing ID anemia in female college students.

Vector Control Scheme of Synchronous Reluctance Motor Considering Iron Loss (철손을 고려한 동기형 릴럭턴스 모터의 벡터제어)

  • 김길환;이중호;김정철;현동석
    • Proceedings of the KIPE Conference
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    • 1997.07a
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    • pp.55-59
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    • 1997
  • In general, Vector control of synchronous reluctance motor(SynRM) is performed under the assumptions that all the parameters are constant and magnetizing flux saturation and iron loss effect can be negligible. Under these assumptions, however, torque nonlinear characteristic can be a possible performance deterioration when precision torque control is needed and operating speed is high. This paper proposes the method, in the Synchronous Reluctance Motor (SynRM), which select appropriate stator d,q-axis currents that the influence of iron core loss on the developed torque can be minimized, and shows that the proposed method is comparable to the algorithm which compensates the iron core loss effect.

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Nutritional Status in Healthy Elderly Koreans from Urban Households (도시 지역에 거주하는 노인의 영양상태에 관한 연구)

  • 천종희
    • Journal of Nutrition and Health
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    • v.21 no.1
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    • pp.12-22
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    • 1988
  • Nutritional Status of 74 elderly Koreans(35 men and 39 women) from middle-income households in Incheon were evaluated in terms of dietary nutrient intakes, anthropometric measurements and biochemical blood analysis. The mean consumptions of all nutrients were lower than R.D.A except iron, thiamine and niacin. However, 25.7% of men and 33.3% of women consumed less amount of iron than 75% of R.D.A. Average body mass index of women was sightly but significantly higher than that of men (P<0.05). Obesity rate and triceps skinfold thickness of women were much higher than those of men (23.3% vs 5.4% and 14.9mm vs 9.6mm, respectively). By judging from amounts of hemoglobin, hematocrit, serum iron, total iron binding capacity, mean corpuscular hemoglobin concentration and transferrin saturation of the elderly, 5.6-33.3% of men and 5.0-33.3% of women seem to be possibly anemic.

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Iron hydrolysis and lithium uptake on mixed-bed ion exchange resin at alkaline pH

  • Olga Y. Palazhchenko;Jane P. Ferguson;William G. Cook
    • Nuclear Engineering and Technology
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    • v.55 no.10
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    • pp.3665-3676
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    • 2023
  • The use of ion exchange resins to remove ionic impurities from solution is prevalent in industrial process systems, including in the primary heat transport system (PHTS) purification circuit of nuclear power plants. Despite its extensive use in the nuclear industry, our general understanding of ion exchange cannot fully explain the complex chemistry in ion exchange beds, particularly when operated at or near their saturation limit. This work investigates the behaviour of mixed-bed ion exchange resin, saturated with species representative of corrosion products in a CANDU (Canadian Deuterium Uranium) reactor PHTS, particularly with respect to iron chemistry in the resin bed and the removal of lithium ions from solution. Experiments were performed under deaerated conditions, analogous to normal PHTS operation. The results show interesting iron chemistry, suggesting the hydrolysis of cation resin bound ferrous species and the subsequent formation of either a solid hydrolysis product or the soluble, anionic Fe(OH)3-.

Hysteresis Characteristics of Flux-Lock Reactor using HTSC (고온초전도체를 이용한 자속구속 리액터의 히스테리시스 특성)

  • Lim, Sung-Hun;Choi, Hyo-Sang;Ko, Seok-Cheol;Lee, Jong-Hwa;Park, Sick;Kang, Hyeong-Gon;Han, Byoung-Sung
    • Proceedings of the KIEE Conference
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    • 2003.10b
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    • pp.89-91
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    • 2003
  • For the design to prevent the saturation of iron core and the effective fault current limitation, the analysis for the operation of the flux-lock type superconducting fault current limiter (SFCL) with consideration for the hysteresis characteristics of iron core is required. In this paper, the hysteresis characteristics of flux-lock reactor, which is an essential component of flux-lock type SFCL, was investigated. The hysteresis loss of iron core in flux-lock type SFCL does not happen due to its winding's structure especially in the normal state. From the equivalent circuit for the flux-lock type SFCL and the fault current limiting experiments, the hysteresis curves could be drawn. Through the analysis for both the hysteresis curves and the fault current limiting characteristics due to the number of turns for the 1st and 2nd winding, the increase of the number of turns in the 2nd winding of the flux-lock type SFCL had a role to prevent the iron core from saturation.

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