• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2005년도 춘계학술발표회
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• pp.1008-1009
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• 2005

In order to screen ionizing radiation induced early-response genes, we employed subtractive hybridization method and isolated a metabolism associated gene. The gene expression was very sensitive to ionizing radiation as revealed by a rapid induction of its messenger RNA. We characterized the function of this gene in radiation response. This gene activated p53 and enhanced cell killing effect of ionizing radiation. This effect was attributable to p53 phosphorylation and transcriptional activation.

• 한국안전학회지
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• 제23권5호
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• pp.49-53
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• 2008

Glow discharge has lots of attractive properties, such as lower discharge sustaining voltage, no generation of ozone, and so on. And more, ionizer was developed recently using an atmospheric pressure glow discharge. On the other hand, ionizer needs a compressed or blown air to transport ion for charged objects. This air is very useful in explosive hazardous area to prevent the explosion of flammable gas and/or vapor by ignition sources, e.g. electrical spark. In this paper, we investigated the ionizing characteristic of atmospheric pressure glow discharge by controlled air flow rate from 5 liters to 60 liters a minute, and compared with decay time between the corona discharge and glow discharge as a function of some direction and distance from discharge ion source. We confirmed that an air flow rate needs 25 liters a minute to sustain the most suitable atmospheric pressure glow discharge and to increase an ionizing efficiency.

• Bulletin of the Korean Chemical Society
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• 제16권11호
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• pp.1104-1108
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• 1995

A measure of stabilities (-ΔHo) and resonance delocalization (-Δq(Cα+)) for some carbocations has been estimated using the semiempirical AM1 method. The stability (-ΔHo) of carbocations can be correlated with the sensitivity (m) of localized cations to the solvent ionizing power scale Y, whereas the extent of resonance delocalization (-Δq(Cα+)) can be correlated with the sensitivity (h) of delocalized cations to the solvent ionizing power scale Ⅰ. It has been shown that two solvent ionizing power scales Y and I have in general opposite signs so that effects of electrostatic solvation are opposite for the localized and delocalized cationic charges. The use of two different solvent scales for a substrate with delocalizable cationic charge is not only prerequisite to the proper correlation of solvolysis rates but also is justified.

• Nuclear Engineering and Technology
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• 제53권7호
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• pp.2075-2083
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• 2021

The article provides a review of the research results obtained during of more than 20 years concerning using the gaseous radiochemical method (GRCM) for detecting of ionizing radiation. This method based on threshold nuclear reactions with production of radioactive noble gas which does not interact with the materials of gaseous tract. The applications of GRCM in the diagnostics of neutrinos, neutrons, charged particles, thermonuclear plasma thermometry, and the study of the structure and dynamics of astrophysical objects, position-sensitive dosimetry of neutron targets with accelerator driving, spatial distribution of the fast neutron flux density in a nuclear reactor allowing the transformation of longitudinal coordinate of neutron flux distribution into a temporal distribution of the radiochemical gas decay counting rate ("barcode" semblance) and measurement of bombarding particles spectra are described. Experimental testing of the described technologies was made on the neutron target driven with the linear proton accelerator of Institute for Nuclear Research of Russian Academy of Sciences (INR RAS).

• 천문학회보
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• 제46권1호
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• pp.30.3-30.3
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• 2021

In order to generate the 3D structure of the 21-cm signal during the reionization, semi-numerical simulations based on Excursion set formalism are broadly used. However, semi-numerical simulations in the realization of the 3D structure are known to be the ionizing photon non-conserving by the structure of the Excursion set approach. Recently, explicit photon conserving algorithms for semi-numerical simulations introduced, but they are still too slow when forward modelling the 21-cm signal with high-dimensional parameter spaces. Here, we introduce a new method for approximately correcting photon non-conservation, which can be applied on-the-fly. This method is tailored towards the efficient simulation and Bayesian inference with high-dimensional parameter space. Then, we investigate how large an impact that photon non-conservation has on astrophysical parameter inference by performing an MCMC analysis. We find that the ionizing escape parameter is deviated from the fiducial value by 2 sigma when we infer astrophysical parameters without this correction.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2008년도 하계종합학술대회
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• pp.1181-1182
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• 2008

The study presents the results of the analysis on the structural characteristics of MOS capacitor for sensing the ionizing radiation effect. Increasing the thickness of MOS capacitor's oxide layer enhanced the sensitivity of MOS capacitor under irradiation condition, but the sensitivity of irradiated MOS capacitor is uninfluenced by the area of MOS capacitor.

• Journal of Radiation Protection and Research
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• 제30권1호
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• pp.27-30
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• 2005

New possibilities are discussed for cholesteric liquid crystals (CLC) as sensor materials for detection of ionizing radiation, biologically active UV radiation, and the presence of hazardous vapors in atmosphere. A distinguishing property of CLC-based detectors is their 'bioequivalence', i.e., mechanisms of their response to external factors essentially imitate the corresponding mechanisms of biological tissues. Such detectors can ensure sufficiently high sensitivity to make feasible their use as alarm indicators or in biophysical studies. Specific examples ate given of sensor compositions and their response characteristics.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 1997년도 제36차 추계학술대회
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• pp.471-473
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• 1997

• 한국산업보건학회지
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• 제25권1호
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• pp.27-35
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• 2015

Objectives: To investigate safety and health management, conditions in factories or facilities handling radiation-generating devices and radioactive isotopes were reviewed in terms of regulations of radiation safety control in Korea. Radiation exposure levels generated at those facilities were directly measured and evaluated for establishing an effective safety and health management plan. Methods: Government organizations with laws and systems of radiation safety and health were investigated and compared. There are three laws governing radiation-related employment such as occupational safety and health acts, nuclear safety acts, and medical service acts. We inspected 12 workplaces as research objects:four workplaces that manufacture and assemble semiconductor devices, three non-destructive inspection workplaces that perform inspections on radiation penetration, and five workplaces in textile and tire manufacturing. Monitoring of radiation exposure was performed through two methods. Spatial and surface monitoring using real-time radiation instruments was performed on each site handling radiation generating devices and radioactive isotopes in order to identify radiation leakage. Results: According to the occupational safety and health act, there is no legal obligation to measure ionizing radiation and set dose limits. This can cause confusion in the application of the laws, because the scopes and contents are different from each other. Surface dose rates in radiation generating devices such as implanters, thickness gages and accelerators, which were registered according to nuclear safety acts, using surveymeters, and seven of 36 facilities(19.4%) exceeded the international standards for surface radiation dose of $10{\mu}Sv/hr$. Conclusions: The results showed that occupational health and safety acts require a separate provision for measuring and assessing the radiation exposure of workers performing radiation work. Like noise, ionizing radiation will also periodically be controlled by including it in the object factors of work-environment measurement.

• 대한방사선방어학회:학술대회논문집
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• 대한방사선방어학회 2011년도 추계 학술발표회 및 심포지엄
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• pp.212-213
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• 2011

The biological effects of low dose ionizing radiation (LDIR) remain insufficiently understood. We examined for the scientific evidence to show the biological effects of LDIR using radiation-sensitive immune cells. We found that Ikaros protein was responsed to low dose-dependent effects of gamma radiation in IM-9 B lymphocytes. Ikaros encodes zinc finger transcription factors that is important regulators of a hematopoietic stem cells (HSCs) progression to the B lymphoid lineage development, differentiation and proliferation. In this study, we observed that cell proliferation was enhanced from 10% to 20% by LDIR (0.05 Gy) in IM-9 B lymphocytes. The Ikaros protein was phosphorylated in its serine/threonine (S/T) region and decreased its DNA binding activity in the cells exposed to LDIR. We found that Ikaros phosphorylation was up-regulated by CK2/AKT pathway and the residues of ser-304 and ser-306 in Ikaros was phosphorylated by LDIR. We also observed that Ikaros protein was localized from the nucleus to the cytoplasm after LDIR and bound with Autotaxin (ENPP2, ATX) protein, stimulating proliferation, migration and survival of immune cells. In addition, we found that the lysoPLD activity of ATX was dependent on Ikaros-ATX binding activity. These results indicate that the Ikaros is an important regulator of immune activation. Therefore, we suggest that low dose ionizing radiation can be considered as a beneficial effects, stimulating the activation of immune cells.