• Title/Summary/Keyword: Ionization rate

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Therapeutic results and safety of postoperative radiotherapy for keloid after repeated Cesarean section in immediate postpartum period

  • Kim, Ju-Ree;Lee, Sang-Hoon
    • Radiation Oncology Journal
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    • v.30 no.2
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    • pp.49-52
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    • 2012
  • Purpose: To evaluate the effectiveness and safety of postoperative radiotherapy for the treatment of keloid scars administered immediately after Cesarean section. Materials and Methods: A total of 26 postpartum patients with confirmed keloids resulting from previous Cesarean sections received either 12 or 15 Gy radiotherapy. The radiotherapy was divided into three 6 MeV electron beam fractions administered during the postpartum period immediately following the final Cesarean section. To evaluate ovarian safety, designated doses of radiation were estimated at the calculated depth of the ovaries using a solid plate phantom and an ionization chamber with the same lead cutout as was used for the treatment of Cesarean section operative scars and a tissue equivalent bolus. Results: In total, the control rate was 77% (20 patients), while six (23%) developed focally elevated keloids (ranging from 0.5 to 2 cm in length) in the middle of the primary abdominal scar. Five patients experienced mild hyperpigmentation. Nonetheless, most patients (96%) were satisfied with the treatment results. The estimated percentage of the applied radiation doses that reached the calculated depth of the ovaries ranged from 0.0033% to 0.0062%. Conclusion: When administered during the immediate postpartum period, postoperative electron beam radiotherapy for repeated Cesarean section scars is generally safe and produces good cosmetic results with minimal toxicity.

A Light-induced Threshold Voltage Instability Based on a Negative-U Center in a-IGZO TFTs with Different Oxygen Flow Rates

  • Kim, Jin-Seob;Kim, Yu-Mi;Jeong, Kwang-Seok;Yun, Ho-Jin;Yang, Seung-Dong;Kim, Seong-Hyeon;An, Jin-Un;Ko, Young-Uk;Lee, Ga-Won
    • Transactions on Electrical and Electronic Materials
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    • v.15 no.6
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    • pp.315-319
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    • 2014
  • In this paper, we investigate visible light stress instability in radio frequency (RF) sputtered a-IGZO thin film transistors (TFTs). The oxygen flow rate differs during deposition to control the concentration of oxygen vacancies, which is confirmed via RT PL. A negative shift is observed in the threshold voltage ($V_{TH}$) under illumination with/without the gate bias, and the amount of shift in $V_{TH}$ is proportional to the concentration of oxygen vacancies. This can be explained to be consistent with the ionization oxygen vacancy model where the instability in $V_{TH}$ under illumination is caused by the increase in the channel conductivity by electrons that are photo-generated from oxygen vacancies, and it is maintained after the illumination is removed due to the negative-U center properties.

A Study on Mixture Preparation in a Port Fuel Injection Sl Engine During Engine Starting (흡기포트 분사방식의 가솔린 엔진에서 냉시동시 혼합기 형성에 관한 연구)

  • 황승환;이종화;민경덕
    • Transactions of the Korean Society of Automotive Engineers
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    • v.10 no.4
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    • pp.15-22
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    • 2002
  • As the emission regulations on the automobiles have been increasingly stringent, precise control of air/fuel ration is one of the most important issues on the gasoline engines. Although many researches have been carried out to identify the fuel transport phenomena in the port fuel injection gasolines, mixture preparation in the cylinder has not been fully understood due to the complexity of fuel film behavior, In this paper, the mixture preparation during cold engine start is studied by using a Fast Response Flame ionization Detector.(FRFID) In order to estimate the transportation of injected fuel from the intake port into cylinder, the wall wetting fuel model was used. The two coefficient($\alpha$,$\beta$) of the wall-wetting fuel model was determined from the measured fuel mass that was inducted into the cylinder at the first cycle after injection cut-in. $\alpha$( ratio of directly inducted fuel mass into cylinder from injected fuel mass) and $\beta$ (ratio of indirectly inducted fuel mass into cylinder from wall wetted fuel film on the wall) was increased with increasing cooling water temperature. To reduce a air/fuel ratio fluctuation during cold engine start, the appropriate fuel injection rate was obtained from the wall wetting fuel model. Result of air/fuel ratio control, air/fuel excursion was reduced.

Identification of Differentially Expressed Proteins at Four Growing Stages in Chicken Liver

  • Lee, K.Y.;Jung, K.C.;Jang, B.G.;Choi, K.D.;Jeon, J.T.;Lee, J.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.10
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    • pp.1383-1388
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    • 2008
  • Because of high growth rate and large deposition of fat in the abdomen, the chicken has been used as a model organism for understanding lipid metabolism, fattening and growing. In this study, differentially expression of proteins in chicken liver, one of the important organs for lipid metabolism, has been investigated at four different growing stages. After separation of proteins using two-dimensional electrophoresis (2-DE), more than 700 protein spots were detected. Among them, 13 growing stage specific proteins in chicken liver were selected and further investigated by matrix-assisted laser adsorptions ionization-time of flight mass spectrometry (MALDI-TOF MS). Of these, 12 proteins were matched to existing proteins based on a database search. The identified fat-related proteins in this study were fatty acid synthase (FASN) and malic enzyme (ME1). These proteins were more highly expressed at week 32 than at other weeks. In order to confirm the differential expression, one of the proteins, FASN, was confirmed by western blotting. The identified proteins will give valuable information on biochemical roles in chicken liver, especially for lipid metabolism.

A Study on the Analytical Characterizations of the Low Flow-Low Power ICP-AES (Low flow-low power 유도결합 플라즈마 원자방출 분광법에서의 분석적 특성에 관한 연구)

  • Yang, Hae Soon;Kim, Young Man;Kim, Sun Tae;Choi, Beom Suk
    • Analytical Science and Technology
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    • v.7 no.3
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    • pp.253-260
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    • 1994
  • Analytical characteristics of low power-low flow inductively coupled plasma-atomic emission spectometry(ICP-AES) has been studied. Although the net intensity of the low power ICP is lower than the moderate power ICP, the signal to background ratio becomes higher since the background intensity decreases with decreasing the RF power. The detection limit of the low power ICP is comparable with that of the moderate power ICP. The dynamic range of the calibration curve of the low power ICP is $10^4{\sim}10^5$. The ionization interferences by alkali metals increase with increasing the carrier gas flow rate, but the effects are not varied significantly with the RF power.

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THERMOLUMINESCENCE DOSIMETRIC PROPERTIES OF Ge- AND Er-DOPED OPTICAL FIBRES AND THEIR APPLICATION IN THE MEASUREMENT OF DEPTH -DOSE IN SOLID WATER PHANTHOM

  • Amin, Y.M.;Abdulla, Y.A.;Khoo, B.H.
    • Journal of Radiation Protection and Research
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    • v.26 no.3
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    • pp.143-147
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    • 2001
  • The dosimetric properties of Ge- and Er-doped optical fibres are studied. The Ge-doped fibre is found to be more sensitive to radiation and there is little fading of TL signal compared with Er-doped fibre. The Ge- and Er-doped fibres showed a linear response over a range of ${\sim}1\;Gy$ to about 120 Gy and ${\sim}1Gy$ to about 250Gy respectively. The Ge-doped fibre is found to be dose-rate independent both for photons and electron beams of energy ranging from 6 to 10 MeV and 6 to 12 MeV respectively. The fibre is energy independent for energy greater than ${\sim}0.1\;MeV$ for photon or 0.1 MeV for electron beam. From the depth-dose measurement, it was found that the position of maximum dose, dmax, increased with increasing energy ranging from ${\sim}2\;cm$ and ${\sim}2.5\;cm$ for 6 MeV and 10 MeV photons respectively. The central axis percentage depth dose at 10 cm depth was found to be in good agreement with the value obtained using ionization chamber.

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Quantitative Analysis of the Twenty Marker Components in Gwakhyangjeonggi-san using Ultra-Performance Liquid Chromatography with Mass Spectrometer (LC-MS/MS를 이용한 곽향정기산(藿香正氣散) 추출물 중 20종 성분의 함량분석)

  • Seo, Chang-Seob;Shin, Hyeun-Kyoo
    • Korean Journal of Pharmacognosy
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    • v.45 no.2
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    • pp.113-120
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    • 2014
  • Generally, Gwakhyangjeonggi-san has been used for treatment of diarrhea-predominant irritable bowel syndrome. In this study, an ultra-performance liquid chromatography-electrospray ionization-mass spectrometer method was established for the simultaneous quantification of marker compounds 1-20 in Gwakhyangjeonggi-san water extract. All analytes were separated by gradient elution using two mobile phases on a UPLC BEH $C_{18}$ ($100{\times}2.1mm$, $1.7{\mu}m$) column and maintained at $45^{\circ}C$. The injection volume was $2.0{\mu}L$ and the flow rate was 0.3 mL/min with detection at mass spectrometer. Regression equations of the compounds 1-20 were acquired with $r^2$ values ${\geq}0.9950$. The values of limit of detection and quantification of all analytes were 0.01-2.79 ng/mL and 0.03-8.37 ng/mL, respectively. The amounts of the compounds 1-20 in Gwakhyangjeonggi-san water extract were not detected $-3,236.67{\mu}g/g$. The established LC-MS/MS methods will be valuable to improve quality control of traditional herbal formula, Gwakhyangjeonggi-san.

2D genus topology of 21-cm differential brightness temperature during cosmic reionization

  • Ahn, Kyung-Jin;Hong, Sungwook E.;Park, Chang-Bom;Kim, Uu-Han;Iliev, Ilian T.;Mellema, Garrelt
    • The Bulletin of The Korean Astronomical Society
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    • v.35 no.2
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    • pp.43.1-43.1
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    • 2010
  • A novel method to characterize the topology of the early-universe intergalactic medium during the epoch of cosmic reionization is presented. The 21-cm radiation background from high redshift is analyzed through calculation of the 2-dimensional (2D) genus. The radiative transfer of hydrogen-ionizing photons and ionization-rate equations are calculated in a suite of numerical simulations under various input parameters. The 2D genus is calculated from the mock 21-cm images of high-redshift universe. We construct the 2D genus curve by varying the threshold differential brightness temperature, and compare this to the 2D genus curve of the underlying density field. We find that (1) the 2D genus curve reflects the evolutionary track of cosmic reionization and (2) the 2D genus curve can discriminate between certain reionization scenarios and thus indirectly probe the properties of radiation-sources. Choosing the right beam shape of a radio antenna is found crucial for this analysis. Square Kilometer Array (SKA) is found to be a suitable apparatus for this analysis in terms of sensitivity, even though some deterioration of the data for this purpose is unavoidable under the planned size of the antenna core.

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2'-Hydroxylation of Genistein Enhanced Antioxidant and Antiproliferative Activities in MCF-7 Human Breast Cancer Cells

  • Choi, Jung-Nam;Kim, Doc-Kyu;Choi, Hyung-Kyoon;Yoo, Kyung-Mi;Kim, Ji-Young;Lee, Choong-Hwan
    • Journal of Microbiology and Biotechnology
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    • v.19 no.11
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    • pp.1348-1354
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    • 2009
  • Bioconversion of the isoflavonoid genistein to 2'-hydroxygenistein (2'-HG) was performed using isoflavone 2'-hydroxylase (CYP81E1) heterologously expressed in yeast. A monohydroxylated product was analyzed by liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) and NMR spectrometry and was identified as 2'-HG. An initial bioconversion rate of 6% was increased up to 14% under optimized conditions. After recovery, the biological activity of 2'-HG was evaluated. Bioconverted 2'-HG showed higher antioxidant activity against 1,1-diphenyl-2-picryl hydrazine (DPPH) and 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radicals than did genistein. Furthermore, 2'-HG exhibited greater antiproliferative effects in MCF-7 human breast cancer cells than did genistein. These results suggest that 2'-hydroxylation of genistein enhanced its antioxidant activity and cell cytotoxicity in MCF-7 human breast cancer cells.

Microstrcture and Mechanical Properties of HfN Films Deposited by dc and Inductively Coupled Plasma Assisted Magnetron Sputtering (직류 및 유도결합 플라즈마 마그네트론 스퍼터링법으로 제조된 HfN 코팅막의 미세구조 및 기계적 물성연구)

  • Jang, Hoon;Chun, Sung-Yong
    • Journal of Surface Science and Engineering
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    • v.53 no.2
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    • pp.67-71
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    • 2020
  • For deposition technology using plasma, it plays an important role in improving film deposited with high ionization rate through high density plasma. Various deposition methods such as high-power impulse magnetron sputtering and ion-beam sputtering have been developed for physical vapor deposition technology and are still being studied. In this study, it is intended to control plasma using inductive coupled plasma (ICP) antennas and use properties to improve the properties of Hafnium nitride (HfN) films using ICP assisted magnetron sputtering (ICPMS). HfN film deposited using ICPMS showed a finer grain sizes, denser microstructure and better mechanical properties as ICP power increases. The best mechanical properties such as nanoindentation hardness of 47 GPa and Young's modulus of 401 GPa was obtained from HfN film deposited using ICPMS at ICP power of 200 W.