• Nuclear Medicine and Molecular Imaging
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• 제42권5호
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• pp.375-382
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• 2008

갑상선암 환자의 방사성 요오드 치료를 위한 전 단계로 시행되는 저요오드식이는 표준화된 전처지 방법으로 사용되고 있고 그 시행방법에 관련된 권고들이 최근 생겨나고 있다. 한국은 상대적으로 요오드 섭취가 많은 지역이므로 권장된 요오드 배설 기준을 만족시키지 못할 수도 있다. 이 연구에서는 갑상선의 요오드 섭취를 억제시키는 약물의 제한, 조영제가 사용된 경우에서 최소 3개월 이후로 치료 일정을 정하기, 전담 영양사에 의한 2주간의 엄격한 저요오드식이 교육을 시행하였을 때, 식이 요오드섭취가 많은 한국 갑상선암 환자들에서 소변 요오드량이 적정 수준으로 감소하는 지에 대해 전향적으로 분석하고자 하였다. 방법: 2006년 11월부터 외부 병원에서 갑상선암 진단 후 갑상선 전절제술을 시행 받고, 잔여 갑상선 제거 목적으로 고용량 방사성요오들 치료를 위해 본 연구자들의 병원에 의뢰된 환자들 중 recombinant human thyrotropin 또는 levotriiodothyronine을 사용하는 경우를 제외한 환자들을 대상으로 하였다. 요오드 함유 약물이나 갑상선의 요오드 섭취를 제한할 수 있는 약물을 점검했고, 조영제가 사용된 경우 치료 일정을 최소 3개월 이후로 결정하였으며 전담 영양사에 의한 2주간의 엄격한 저요오드식이 교육을 시행하였다. 저요오드식이 전후로 24시간 소변 내 요오드량을 측정하여 비교하였다. 또한 소변 내 크레아티닌 수치를 이용해서 24시간 소변 채집이 보다 적절한 것으로 판단되는 하부군을 대상으로 24시간 소변 내 요오드량을 비교하였다. 결과: 총 51명이 최종 분석에 포함되었다. 모든 환자에서는 24시간 소변 요오드량이 저요오드식이 전후로 $787\;{\mu}g/d$에서 $85\;{\mu}g/d$로 감소가 되었고 74.4%에서 $100\;{\mu}g/d$ 이하의 결과를 보였다. 소변 채집이 보다 적절한 하부군 14례에서는 저요오드식이 전후로 $505\;{\mu}g/d$에서 $99\;{\mu}g/d$로 감소되었고 78.6%에서 $100\;{\mu}g/d$ 이하의 결과를 보였다. 결론: 갑상선암 환자들에서 잔여갑상선제거를 위한 방사성요오드 치료 전에 2주간의 엄격한 저요오드식이를 시행하여 전향적으로 분석했을 때 24 시간 소변 내 요오드량이 평균 $99\;{\mu}g/d$로 감소하였고, 78.6%에서 $100\;{\mu}g/d$이하의 값을 보였다. 따라서 식이 요오드섭취량이 많은 한국에서는 최소 2주 이상의 엄격한 저요오드식이가 고려되어야 하며, 환자의 순응도를 높이기 위한 체계적인 교육이 뒷받침되어야 한다.

• 한국임상수의학회지
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• 제9권1호
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• pp.277-281
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• 1992

To investigate the effect of chlorhexidine gluconate and povidone iodine on wound healing, their antimicrobial activity and their effects on wound contraction in rabbits were studied. Staphyococcus aureus (1${\times}$10$\^$7/) was inoculated on the full thickness skin defects (2${\times}$2cm) on the back. Antiseptics were applied on the defects 2 hours after Inoculation. The defects were swabbed for bacterial culture 24 and 48 hours after the application of antiseptics. Percentage of wound contraction, based on wound area measured on the day of surgery was calculated for each wound on days 1,7 and 14. The 0.5% chlorhexidine gluconate solution had more effective antimicrobial activity against Staphyococcus aureus in wounds than 0.05% chlorhexidine gluconate solution (p<0.05), and povidone iodine solution and saline (p<0.01). Percentages of wound contraction were not significantly different among different dilutions of the antiseptics and saline. Present study indicated that the antimicrobial activity of chlorhexidine gluconate in wound was superior to that of povidone iodine.

• Macromolecular Research
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• 제10권5호
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• pp.286-290
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• 2002

The FT-Raman spectra of trans-polyacetylene films doped lightly with iodine were obtained with the 1320-nm laser line. The observed Raman bands are attributed to positively charged domains created by acceptor doping. The observed Raman wavenumbers of the V$_2$, (CC stretch), V$_3$, and V$_4$ bands (mixed of CC stretch and CH in-plan bending) of iodine-doped form are slightly higher than those of the corresponding bands of pristine trans-polyacetylene, whereas the contrary is the case for V$_1$, and (C=C stretch) of iodine-doped form. In particular, these upshifts of the V$_2$ and V$_3$ bands are distinguished from the downshifts of these bands in donor doping. The origin of doping induced Raman bands is discussed in terms of solitons and polarons.

• 한국염색가공학회지
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• 제16권3호
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• pp.14-21
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• 2004

In this research, we accomplished in order to improving color fastness of sublimation for Poly (vinyl alcohol) (PVA)-iodine polarized film. The poor iodine sublimation problem has greatly improved by $O_2$ low temperature plasma treatment. We obtained the followings: (1) plasma treatment has contributed in adhesive ability via peel strength, AFM image and roughness were investigated, But the improvement in adhesive strength was not linearly proportional to the treatment time. (2) $O_2$ plasma treated PVA-iodine polarized film was good enough as to maintain the transmittance and polarization even after iodine cone. of 0.05mol/L and dipping time of 50sec. (3) $O_2$ low temperature plasma treated PVA-iodine polarized film has obtain high durability because of good adhesive strength.

• 대한화학회지
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• 제6권1호
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• pp.69-72
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• 1962

Spectrophotometric studies have been made on the solutions of elementary iodine in pyridine and quinoline, in the absence of light. The results shown that triiodide ion is produced in both solutions with different rates, and that triiodide ion behaves differently in both solutions. Iodine reacts slowly with pyridine, giving rise to triiodide ion, which is relatively stable in this solvent, hereas, iodine reacts rapidly with quinoline, forming triiodide ion, which interacts further with the medium at slow rate. It has been thought that the difference of the behavior of triiodide ion in both solutions may be due to the stronger basicity of quinoline than pyridine.

• 대한족부족관절학회지
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• 제16권3호
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• pp.190-192
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• 2012

In the extremity surgery, pneumatic tourniquet and povidone-iodine solution are commonly used to provide an aseptic, bloodless field, and their complication rate has remained low. However, chemical burn under tourniquet has been rarely reported. Patients sustained burn injuries over the dependent, weight-bearing regions such as posterior neck, back, buttocks and posterior thighs. This rare adverse complication occurred in a 22-year-old man who underwent modified Brostrom operation with arthroscopic os trigonum excision. 10% povidone-iodine was used as topical antiseptic, and full thickness burn occurred underneath the area of tourniquet application. Main causes of povidone-iodine related chemical burn are considered maceration, irritation of the skin, long term use of the tourniquet and pressure. To reduce the complications like chemical burn, awareness of the risk and the possible pathogenesis as well as the preventive measures is important in surgical practice.

• Journal of the Optical Society of Korea
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• 제16권4호
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• pp.325-330
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• 2012

Differential absorption LIDAR (DIAL) is frequently used for atmospheric gas monitoring to detect impurities such as nitrogen dioxide, sulfur dioxide, iodine, and ozone. However, large differences in the on- and off-line laser wavelengths can cause serious errors owing to differential aerosol scattering. To resolve this problem, we have developed a new DIAL system for iodine vapor measurements in particular. The suggested DIAL system uses only one laser under seeded and unseeded conditions. To check the detection-sensitivity and error effects, we compared the results from a system using two seeded lasers with those from a system using a seeded and an unseeded laser. We demonstrate that the iodine concentration sensitivity of our system is improved in comparison to the conventional two seeded or two unseeded laser combinations.

• 동서간호학연구지
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• 제22권2호
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• pp.148-157
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• 2016

Purpose: The purpose of this study was to explore the meaning of the experience of receiving radioactive iodine therapy among patients with thyroid cancer. Methods: A qualitative research design was adopted. The participants were ten women diagnosed with thyroid cancer who had received radioactive iodine therapy within one year. Data were collected through in-depth interviews from October of 2015 to April of 2016. Individual interviews were recorded, and transcribed data were analyzed using Colaizzi's method. Results: The six categories of the experience of receiving radioactive iodine therapy were "Finally realizing having cancer," "The lonely fight that feels like prison life," "Narrower scope of life," "Lack of understanding by others," "Enduring a short, yet difficult journey," and "A turning point for a new life." Conclusion: This study provides deep insight into the experience of thyroid cancer patients who had received radioactive iodine therapy. Nurses should concern their distress during radioactive iodine treatment and manage psychological difficulties as well as physical symptoms. Support from family and health care providers may help them to overcome the hard journey.

• Bulletin of the Korean Chemical Society
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• 제18권4호
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• pp.385-389
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• 1997

We report on the development of a new method to control the coverage of a metal film prepared with immersion method. An Sb species in solution adsorbed irreversibly at an open circuit potential (∼0.2 V) as an oxygenous Sb(Ⅲ) on a clean Au electrode, and the adsorbates showed voltammetric features in the potential range from 0.1 V to - 0.4 V. The full coverage of the Sb adsorbates was ∼0.45. On the contrary, the Sb species in solution did not adsorb at all on iodine-covered Au electrode surfaces, when the iodine coverages were more than 0.25. As the iodine coverage decreased below 0.25, however, the irreversible adsorption of Sb took place and the coverage of Sb increased accordingly. This electrochemical behavior has been interpreted as the penetration of the adsorbing Sb species in solution through open spaces among the iodine adlattices of coverages less than 0.25. With the manipulation of the iodine coverage, the controllable range of Sb coverage was from 0 to 0.45, i.e. the full coverage of Sb. In addition, the reversible deposition of Sb on an iodine-saturated Au electrode with voltammetric scan has been observed, which is contrasted with the adsorptive behavior of Sb on the clean Au electrode.

• Archives of Plastic Surgery
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• 제37권3호
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• pp.213-219
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• 2010

Purpose: Iodine has been used for the prevention or management of wound infection as a topical agent. Although iodine was widely used mainly by Betadine$^{(R)}$ and cadexomer iodine, there was no comparative study on the efficacies of dressing methods of iodine. And also it's wound healing effect was not yet clear. The purpose of this study is to compare antibacterial effects and wound healing effects associated with various dressing methods of iodine on infected full thickness skin defect in the mouse. Methods: One full thickness skin defects in the mice (n=60) were developed on the back and left open for twenty-four hours. Sixty mice were divided into four groups : group S (dressing with Betadine$^{(R)}$ soaking, n=15), group T (dressing with Betadine$^{(R)}$ topping, n=15), group I (dressing with Iodosorb$^{(R)}$, n=15), group G (control group, dressing with dry gauze, n=15). The size of the wound defects and the grades of wound healing were evaluated in 4, 7, 10 days, and antibacterial effect was evaluated with restricted zone in Mueller Hinton agar by disk diffusion method. Results: After the wound was left open for twenty-four hours, many Staphylococcus aureus were cultured. The wound defect size was decreased in order of Betadine$^{(R)}$ soaking, Iodosorb$^{(R)}$, Betadine$^{(R)}$ topping and gauze dressing group in all days, but difference among experimental groups was not statistically significant. The grade score of wound healing was increased in order of Betadine$^{(R)}$ soaking, Iodosorb$^{(R)}$, Betadine$^{(R)}$ topping and gauze dressing group, and the difference was statistically significant. Antibacterial effect for S. aureus was increased in order of Iodosorb$^{(R)}$, Betadine$^{(R)}$ soaking, Betadine$^{(R)}$ topping and gauze dressing group, and the difference was statistically significant. Conclusion: Selection of the effective dressing method of iodine for infected wounds remains a controversial decision. According to this study, Iodosorb$^{(R)}$ may be most effective method for antibacterial effect and Betadine$^{(R)}$ soaking may be most effective method for infected wound healing. However, further study is necessary to evaluate the clinical efficacy of dressing methods of iodine and to search for the mechanisms that explain their effects.