• Title/Summary/Keyword: Investigative

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Longevity Genes: Insights from Calorie Restriction and Genetic Longevity Models

  • Shimokawa, Isao;Chiba, Takuya;Yamaza, Haruyoshi;Komatsu, Toshimitsu
    • Molecules and Cells
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    • v.26 no.5
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    • pp.427-435
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    • 2008
  • In this review, we discuss the genes and the related signal pathways that regulate aging and longevity by reviewing recent findings of genetic longevity models in rodents in reference to findings with lower organisms. We also paid special attention to the genes and signals mediating the effects of calorie restriction (CR), a powerful intervention that slows the aging process and extends the lifespan in a range of organisms. An evolutionary view emphasizes the roles of nutrient-sensing and neuroendocrine adaptation to food shortage as the mechanisms underlying the effects of CR. Genetic and non-genetic interventions without CR suggest a role for single or combined hormonal signals that partly mediate the effect of CR. Longevity genes fall into two categories, genes relevant to nutrient-sensing systems and those associated with mitochondrial function or redox regulation. In mammals, disrupted or reduced growth hormone (GH)-insulin-like growth factor (IGF)-1 signaling robustly favors longevity. CR also suppresses the GH-IGF-1 axis, indicating the importance of this signal pathway. Surprisingly, there are very few longevity models to evaluate the enhanced anti-oxidative mechanism, while there is substantial evidence supporting the oxidative stress and damage theory of aging. Either increased or reduced mitochondrial function may extend the lifespan. The role of redox regulation and mitochondrial function in CR remains to be elucidated.

Situating the Complex Social Functions of a Well-known Investigative Program through a Textual and Production Analysis (SBS <그것이 알고 싶다>의 역할과 성취 그리고 명과 암을 맥락화하기 텍스트 분석과 미디어 생산자연구를 통해서 조명하기)

  • Lee, Keehyeung;Hwang, Kyongah
    • Korean journal of communication and information
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    • v.75
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    • pp.83-144
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    • 2016
  • SBS's -also known as - is one of the most famous investigative programs in South Korean television sector. This program is well-known for its much detailed and tenacious investigation of unsolved crimes, various social wrong-doings, as well as public scandals through a mystery code and meticulous storytelling. As a result, generates much popular interests and responses from local audiences. This work both examines and contextualizes the multiple roles and implications of this program through a textual and production analysis. Especially, it critically pursues this program's achievements and limits in the context of the changing roles of investigative journalism and its unstable status at current juncture.

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A Study on the Topic Modeling Analysis of Book Reports on Personality Types and Interest Types (성격유형과 흥미유형에 따른 독서 감상문 토픽 분석 연구)

  • Jeong-Hoon Lim
    • Journal of the Korean Society for information Management
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    • v.40 no.1
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    • pp.175-198
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    • 2023
  • This study aimed to investigate the difference in response to reading as shown in book reports by personality type and interest type. For this purpose, personality type analysis data, interest type analysis data, and book report data written in subject reading activities were collected from 81 third graders at D Science High School in Daejeon. Topic analysis was conducted on the collected book reports, and the probability of a topic being mentioned was statistically tested according to personality type (thinking type, feeling type) and interest type (investigative type, types other than investigative). Subsequently, the conceptual connection structure of words was measured by keyword network analysis, and the analysis results of topic modeling were complemented by the centrality index. As a result of the study, the topic regression analysis showed statistically significant differences between thinking type (T) and feeling type (F) in topic 2 (understanding and studying) and topic 3 (reading and thinking), and statistically significant differences between investigative type and non-investigative type in topic 2 (understanding and studying). The results of this study can be used as a basis for tailored book recommendations and personalized reading education.

Authentic Investigative Activities for Teaching Ratio and Proportion in Elementary and Middle School Mathematics Teacher Education

  • Ben-Chaim, David;Ilany, Bat-Sheva;Keret, Yaffa
    • Research in Mathematical Education
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    • v.12 no.2
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    • pp.85-108
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    • 2008
  • In this study, we created, implemented, and evaluated the impact of proportional reasoning authentic investigative activities on the mathematical content and pedagogical knowledge and attitudes of pre-service elementary and middle school mathematics teachers. For this purpose, a special teaching model was developed, implemented, and tested as part of the pre-service mathematics teacher training programs conducted in Israeli teacher colleges. The model was developed following pilot studies investigating the change in mathematical and pedagogical knowledge of pre- and in-service mathematics teachers, due to experience in authentic proportional reasoning activities. The conclusion of the study is that application of the model, through which the pre-service teachers gain experience and are exposed to authentic proportional reasoning activities with incorporation of theory (reading and analyzing relevant research reports) and practice, leads to a significant positive change in the pre-service teachers' mathematical content and pedagogical knowledge. In addition, improvement occurred in their attitudes and beliefs towards learning and teaching mathematics in general, and ratio and proportion in particular.

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Cloud Services for the forensic aspects of the investigative methods (클라우드 서비스에 대한 포렌식 측면의 수사 방법)

  • Park, Gi-Hong;No, Si-Young
    • Journal of Korea Society of Industrial Information Systems
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    • v.17 no.1
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    • pp.39-46
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    • 2012
  • In this paper, for the cloud system by explaining how the forensic aspects of the investigation. Smartphone Growth Entering a variety of applications were developed which cloud systems of personal information and information assets sharing applications as during incidents on the case evidence collection, an important factor, whereas such systematic investigative methods, born in the course of my investigation of the can be confusing. This paper on the forensic aspects of the cloud system by proposing a crime scene investigation procedures, investigative support, and aiding in the systematic collection of data to support evidence.

A Study on the Characteristics of lawsuits between the Freedom of the Press and Individual Rights over the Investigative Reporting Program (TV탐사보도 프로그램의 법적분쟁에 나타난 특성 연구)

  • Lee, Seung-Sun
    • Korean journal of communication and information
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    • v.29
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    • pp.233-269
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    • 2005
  • The purpose of the study is to explore the characteristics of lawsuits against investigative reporting programs of the broadcast media. This study proposed three research questions: (1) what were the characteristics of court derisions on the investigative reporting programs? (2) what were the reasonings on which judges rely in the lawsuits for a right of reply? (3) what were the critical issues and how the libel laws were applied in balancing between the freedom of the press and the protection of individual rights. To answer these questions, the study employed quantitative and qualitative methods analysing 35 related cases. This study revealed that investigative reporting programs must deal with the Issues of 'public figures' and 'matters of public concern' to be protected under the freedom of the press. The study also found that the broadcast media must prove legitimate public interests and the truth of the facts to prevail in a case. In 1999, the Constitutional Court of Korea held that pubic figures in libel cases must be regarded differently from private figures. In accordance with the decision, the Supreme Court has applied differing criteria for public figures in libel cases. However, courts have not set a clear definition of the public figure yet. To advocate the freedom of the press, as the results of this study indicate, TV producers and journalists should behave lawfully in the course of newsgathering and provide the opportunities of reply for their news sources.

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Cheonan Patrol Combat Corvette Sinking and Media Control: A Production Study on Investigative Programs (천안함 침몰 사건과 미디어 통제: 탐사보도 프로그램 생산자 연구)

  • Kim, Sang-Gyoon;Han, Hee Jeong
    • Korean journal of communication and information
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    • v.66
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    • pp.242-272
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    • 2014
  • This study examines why follow-up investigative programs about the sinking of the Cheonan Patrol Combat Corvette(ROKS Cheonan) have not been produced, despite much speculation surrounding the cause of the sinking since November 2010, when KBS investigative program, In-Depth 60 Minutes which had covered the incident was aired. We have uncovered four reasons through a series of in-depth interviews with producers and reporters, as follows. First, Korean military authorities monopolized relevant information, while the producers could not prove or confirm the validity of the findings of the JIG(Joint Civilian-Military Investigation Group)'s report because the facts had been revealed partially and selectively by the authorities and the press' scientific investigation were rejected by the authorities. Second, the crew of In-Depth 60 Minutes was subjected to severe disciplinary action by the Korea Communications Commission. This caused a chilling effect, - it broke the producers' resolve to further explore the reason behind the sinking. Furthermore, the screening of the investigative documentary, Project Cheonan Ship was cancelled without prior notice, presumably by the power of the State and markets. Third, the reorganization and shake-up of personnel by broadcasting stations' presidents appointed by the power of the State crushed the spirit of PD Journalism. Finally, the "red purge" factions stigmatized by the political or military, or the mainstream press, caused the producers or broadcasters to engage in self-censorship. The idea has been used in Korea as a smoke screen to deflect public attention. Nevertheless, the producers hope to shed light on the Cheonan sinking incident and to prove reasonable doubts by pursuing follow-up investigations.

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