• Journal of Biosystems Engineering
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• 제24권1호
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• pp.25-30
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• 1999

The effectiveness of many greenhouse environment control methodologies depends on the growth information of crops. Acquisition of the growth information of crops requires a non-invasive and continuous monitoring method. Crop growth monitoring system using digital imaging technique was developed to conduct non-destructive and intact plant growth analyses. The monitoring system automatically measures crop growth information sends an appropriate control signal to the nutrient solution supplying system. To develop the monitoring system, a linear model that explains the relationship between the fresh weight and the top projected leaf area of a lettuce plant was developed from an experiment. The monitoring system was evaluated buy successive lettuce growing experiments. Results of the experiments showed that the developed system could estimate the fresh weight of lettuce from a lettuce image by using the linear model and generate an EC control signal according to the lettuce growth stage.

• 대한의용생체공학회:의공학회지
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• 제23권5호
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• pp.397-403
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• 2002

뇨당 측정 시스템은 소변 속의 글루코오스 농도를 측정함으로서 당뇨 수치를 모니터링하는 비침습적인 당뇨병 자가 진단 장치이다. 본 논문에서는 기존의 침습형 혈당측정방법의 불편성과 비색계를 이용한 뇨당 검사법의 단점을 보완한 뇨당 측정시스템을 설계하였다. 뇨당 측정시스템은 뇨당 측정용 화학센서, 신호검출부, 디지털 제어 및 신호분석부, 디스플레이부 및 전원부로 구성된다. 뇨당측정용 센서로는 재현성이 뛰어나고 다루기가 간편하며 저렴한 가격으로 대량 생산할 수, 있는 일회용 뇨당측정용 전류화학센서를 개발하였다. 설계한 뇨당 측정시스템의 성능을 평가하기 위하여 사람의 소변에 임의의 농도의 글루코오스 성분을 섞은 용액에 대하여 글루코오스 성분 분석시 사용되는 표준장비와의 비교분석을 통해서 글루코오스 농도 검출에 대한 신뢰성 평가를 수행하였다. 회귀분석에 기초한 신뢰성 평가를 수행한 결과 표준오차는 2.85282로 나타났다. 또한, 화학센서를 사용해서 측정하는 시스템을 평가 시 중요한 파라미터인 S.D(Standard Deviation)는 10%로서 임상적으로 유효한 15% 범주 내에 있음을 확인하였고, C.V(Coefficient of Validation)값은 ,5%이내이므로 혈당센서의 기준으로 평가해 볼때 만족하는 결과를 보였다.

• 대한의생명과학회지
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• 제28권4호
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• pp.223-228
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• 2022

It has well reported that tumor markers have many advantages like minimally invasive, convenient use, low cost but also has many limitations like low sensitivity and specificity, relevance of prognosis, low organ specificity. Although no tumor markers are ideal, many tumor markers are used for cancer diagnosis, treatment monitoring, and surveillance monitoring after treatment. We review the classification and characteristics of tumor markers according cancer types and clinical roles in current times.

• 한국산학기술학회논문지
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• 제19권11호
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• pp.488-496
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• 2018

본 연구는 강원도 생태계 교란식물 관리 제거사업 추진 현황을 종합적으로 평가하여, 교란식물의 효율적인 관리방안을 모색하는 것이다. 또한 근본적인 해결방안을 도출하여 예산투입의 효율성 제고, 생태계 기능 향상, 일자리 창출 및 소득화와 연계하여 지역경제 활성화 등을 제안하고자 한다. 생태계 교란식물 분포지역은 하천변이 39.6%로 가장 많았으며, 도로변 23.3%, 도로변-하천변 12.4%, 경작지 주변 및 제방 4.6% 등의 순으로 나타났다. 생태계 교란식물 관리방안으로는 i) 생태계 교란식물 모니터링 및 관리체계 구축, ii) 도민, 민간단체, 군(軍)부대 참여 활성화, iii) 대체식물 식재, iv) 생태계 교란식물 활용 산업 육성 등을 제안하였다. 본 연구 결과를 기초로 향후 추진되어야할 정책으로 i) 생태계 교란식물 관련 법률 제도 개선, ii) 생태계 교란식물 관리 협력체계 구축, iii) 민간 전문가 양성교육 사업 추진, iv) 생태계 교란식물 제거사업 방식의 병행 추진, v) 시 군별 대체식물 식재 모델 개발, vi) 생태계 교란식물을 활용한 산업 육성, vii) 재원확보 및 효율화를 위한 한강 수계관리기금 활용 등을 제안하였다.

• 한국환경복원기술학회지
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• 제7권3호
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• pp.35-47
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• 2004

In order to study changes in vegetation pursuant to rooftop revegetation plantation methods, plantation methods for rooftop revegetation were divided into two types through an analysis of recent trends. Then, Planted plants and invasive plants on sites where the planting methods were introduced were monitored. Planting methods were divided into mono-layer meadow cover type and multi-layer planting cover type. They showed some differences in terms of the availability of wetland, the structure of vegetation layers, the planted species, and the material of mulching. According to the results of monitoring the two sample sites for different plantation methods, the number of invasive plants was higher in multi-layer planting cover type and the ratio of naturalized plants was higher by 30% in average in mono-layer meadow cover type. The main reason for such a result is that the natural soil used in the multi-layer planting cover type likely contained some seeds. Moreover, it's harder for invasive plant seeds to germinate in volcanic rocks than in natural soil. Also, it is attributable to wetlands available in multi-layer planting cover type and diverse living environments created by multi-layer planting. The reason of the ratio of naturalized plants being higher by at least 10% in mono-layer meadow cover type is the character of naturalized plants being stronger in unfavorable conditions than nature plants are. Accordingly, the germination rate in the volcanic rock mulching has likely contributed in raising the introduction and germination of naturalized plants. The results showed that multi-layer planting cover type using wetland creation and nature soil can increase the number of invasive plants and lower the ratio of naturalized plants. However, since seeds contained in the natural soil can affect the growth of planted plants, this needs to be clarified, It was judged that mono-layer meadow cover type may affect more greatly on the germination and growth of invasive plants than on those of planted plants, Its potential adoption in highly urbanized areas was examined. By complementing with the mutual benefits of each plantation method, it appeared possible to shift to a rooftop revegetation system suitable to the site.

• 환경영향평가
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• 제32권2호
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• pp.94-111
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• 2023

효과적인 외래생물 관리 전략 수립을 위해서는 도입 및 확산 여부 평가를 위한 정기 모니터링이 요구된다. 환경 DNA (eDNA, environmental DNA) 메타바코딩은 높은 검출 민감도를 가지고 다수의 종을 동시에 검출할 수 있어 외래생물의 출현 여부와 그 영향을 평가하는데 활발히 활용되고 있다. 국내에서는 어류를 중심으로 메타바코딩의 적용 가능성 평가가 이루어지고 있으며 타 분류군에 대한 연구는 부족한 실정이다. 따라서 본 연구에서는 환경 DNA 메타바코딩을 활용한 국내 외래생물 탐지 가능성을 확인하고자 했다. 분류군별 검출 가능성을 확인하기 위해 어류, 포유류, 조류, 양서류를 목표로 디자인 된 4가지 범용 프라이머(MiFish, MiMammal, Mibird, Amp16S)를 활용하여 대상종 검출 여부를 평가하였다. 그 결과, 총 55개 지점 중 17개 지점(Trachemys scripta, 3개 지점; Cervus nippon, 3개 지점; Micropterus salmoides, 7개 지점; Rana catesbeiana, 4개 지점)에서 대상종의 서식이 확인되었다. 대상지 내 조밀한 지점 선정에도 생태적 특성을 반영한 검출 지점에 차이가 나타났다. 큰입배스와 붉은귀거북을 중심으로 외래생물이 출현이 생물 군집구조(종 풍부도, 풍부도, 다양도)에 미치는 영향을 비교한 결과, 외래생물이 서식하는 지점에서의 다양도가 더 높게 나타났다. 또한 외래생물 출현 지점에서 출현 종 수가 1~4종 추가 검출되었으며 풍부도 또한 1.7배 높게 나타났다. 메타바코딩을 통한 외래생물 검출 결과 및 군집구조 비교는 eDNA를 통한 다량의 모니터링 데이터 구축이 다차원적 생태계 평가에 효율적으로 활용될 수 있음을 나타냈다. 또한 환경의 인위적, 자연적 변화에 따른 생물상 변화를 관찰하고 자연생태 분야의 환경영향평가 등 현황 평가 및 예측을 위한 주요한 기초자료로 활용 가능성을 제시하였다.

• Smart Structures and Systems
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• 제17권5호
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• pp.795-817
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• 2016

A non-contact, in-situ and non-invasive technique for health monitoring of submerged fiber reinforced polymers (FRP) laminates has been developed using ultrasonic guided waves. A pair of mobile transducers at specific angles of incidence to the submerged FRP specimen was used to excite Lamb wave modes. Lamb wave modes were used for comprehensive inspection of various types of manufacturing defects like air gaps and missing epoxy, introduced during manufacturing of FRP using Vacuum Assisted Resin Infusion Molding (VARIM). Further service induced damages like notches and surface defects were also studied and evaluated using guided waves. Quantitative evaluation of transmitted ultrasonic signal in defect ridden FRPs $vis-{\grave{a}}-vis$ healthy signal has been used to relate the extent of damage in FRPs. The developed technique has the potential to develop into a quick, real time health monitoring tool for judging the service worthiness of FRPs.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 학술회의 논문집 정보 및 제어부문 B
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• pp.920-923
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• 2003

An wearable electrocardiogram (ECG) monitoring system is a widely used non-invasive diagnostic tool for ambulatory patient who may be at risk from latent life-threatening cardiac abnormalities. In this paper, we have a portable ECG monitoring system with conductive fiber which was characterized by the small-size and the low power consumption. The system consists of conductive fibers, one-chip microcontroller, ECG preprocessing circuit, and monitoring software to be able to record and analyze in PC. ECG preprocessing circuit is made of pre-amplifier with gain of 10, band-pass filter with bandwidth of 0.5-120Hz and 2.5V offset circuit for A/D conversion. ECG signals obtained by sensor are included with corrupted noises such as a baseline wandering, 60 Hz power noise and interference noise by body movement. For cancellation corrupted noises in signals obtained by conductive fiber, we used the wavelet decomposition of wavelet transforms in MATLAB toolbox.

• Nuclear Medicine and Molecular Imaging
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• 제40권2호
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• pp.96-105
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• 2006

Molecular imaging has its root in nuclear medicine and gene therapy monitoring. Therefore, recent progress in the development of non-invasive imaging technologies, particularly nuclear medicine, should allow molecular imaging to play a major role in the field of gene therapy. These tools have recently been validated in gene therapy models for continuous quantitative monitoring of the location, magnitude, and time-variation of gene delivery and/or expression. This article reviews the use of radionuclide imaging technologies as they have been used in imaging gene delivery and gene expression for gene therapy applications. The studios published to date lend support that noninvasive imaging tools will help to accelerate pre-clinical model validation as well as allow for clinical monitoring of human gene therapy.

• Tuberculosis and Respiratory Diseases
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• 제79권3호
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• pp.158-164
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• 2016

Background: One to three percent of cases of acute tuberculosis (TB) require monitoring in the intensive care unit (ICU). The purpose of this study is to establish and determine the mortality rate and discuss the causes of high mortality in these cases, and to evaluate the clinical and laboratory findings of TB patients admitted to the pulmonary ICU. Methods: The data of patients admitted to the ICU of Yedikule Chest Diseases and Chest Surgery Education and Research Hospital due to active TB were retrospectively evaluated. Demographic characteristics, medical history, and clinical and laboratory findings were evaluated. Results: Thirty-five TB patients (27 males) with a median age of 47 years were included, of whom 20 died within 30 days (57%). The Acute Physiology and Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure Assessment (SOFA) scores were significantly higher, and albumin and $PaO_2/FIO_2$ levels were significantly lower, and shock, multiple organ failure, the need for invasive mechanical ventilation and drug resistance were more common in the patients who died. The mortality risk was 7.58 times higher in the patients requiring invasive mechanical ventilation. The SOFA score alone was a significant risk factor affecting survival. Conclusion: The survival rate is low in cases of tuberculosis treated in an ICU. The predictors of mortality include the requirement of invasive mechanical ventilation and multiple organ failure. Another factor specific to TB patients is the presence of drug resistance, which should be taken seriously in countries where there is a high incidence of the disease. Finding new variables that can be established with new prospective studies may help to decrease the high mortality rate.