• Proceedings of the Korean Geotechical Society Conference
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• 2000.11a
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• pp.361-368
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• 2000

In other to examine the compressibility characteristics of cohesive soils in the mouth of the Nakdong river, the oedometer tests were peformed on undisturbed and reconstituted samples obtained by continuous boring typically at 3 different sites. It is meaningful to compare the consolidation behavior of natural clays with a reference state because the natural clays are depending on the stress history, sedimentary environment and geological history. In this study, the insitu state of the Pusan clays was investigated using the concepts of ISL(Nagaraj, 2000) and ICL and SCL(Burland, 1990). And for the purpose of confirming the existence of the underconsolidated clays, a standpipe type piezometer test and a dissipation test by piezocone were performed at their sites. Consequently, the Pusan clays were evaluated as normally consolidated clays.

• Journal of Electrical Engineering and Technology
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• v.13 no.5
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• pp.1807-1813
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• 2018

In this paper, the fault line selection and location problems of single line-to-ground (SLG) fault in distribution network are addressed. Firstly, the adaptive filtering property for empirical mode decomposition is formulated. Then in view of the different characteristics showed by the intrinsic mode functions(IMF) under different fault inception angles obtained by empirical mode decomposition, the sign of peak value about the low-frequency IMF and the capacitance transient energy is chosen as the fault line selection criteria according to the different proportion occupied by the low-frequency components. Finally, the fault location is determined based upon the comparison result with adjacent fault passage indicators' (FPI) waveform on the strength of the interaction between the distribution terminal unit(DTU) and the FPI. Moreover, the logic nodes regarding to fault line selection and location are newly expanded according to IEC61850, which also provides reference to acquaint the DTU or FPI's function and monitoring. The simulation results validate the effectiveness of the proposed fault line selection and location methods.

• Bulletin of the Korean Chemical Society
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• v.23 no.12
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• pp.1769-1772
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• 2002

Previous $^{19}F\;and\;^{1,2}H$ electron-nuclear double resonance (ENDOR) study of fluorometmyoglobin (MbF) in frozen-solution state provided sensitive tools sensing subtle structural changes of the heme that are not obtainable from X-ray. [Fann et al., J. Am. Chem. Soc. 1995, 117, 6019] Because of the intrinsic inhomogeneouse EPR line broadening effect of MbF in frozen-solution state, detection of the intrinsic inhomogeneouse EPR line broadening effect of MbF in frozen-solution state, detection of the electronic and geometrical changes of the heme ring itself and the proximal histidine by using $^{14}N$ CW ENDOR was interfered. In the present study, hyperfine-sensitive $^{14}N$ Mims ENDOR technique of pulsed-EPR was employed to probe the changes. With two different $\tau$ values of 128 and 196 ns, $^{14}N$ ENDOR signals of the heme and proximal histidine were completely resolved at $g'_{II}(=g_e=2)$. This study present that X-band $^{14}N$ Mims ENDOR sequence can sensitively detect the small changes of the spin densities and p orbital populations of the proximal and the heme nitrogens, caused by ligand and pH variation of the distal site.

• JSTS:Journal of Semiconductor Technology and Science
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• v.2 no.1
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• pp.87-92
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• 2002

We present a simple experimental method for determination of limiting intrinsic fixed-pattern non-uniformity (NU) due to fabrication process in two-dimensional CCD multiplexers (MUXs) that are used for hybrid focal plane arrays. Here, this is done by determining separately the two NUs viz. that are $V_T$ dependent and $V_T$ independent. From these measurements, process dependent NU can be extracted. It is argued that $V_T$ dependent NU can be eliminated by designing novel input circuits whereas $V_T$ independent NU, primarily, dependent on process control and material variations may be reduced but cannot be eliminated completely and hence limits the FPA performance eventually.

• Proceedings of the KIEE Conference
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• 1999.07c
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• pp.1158-1160
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• 1999

This paper proposes a SSSC(Static Synchronous Series Compensator) power flow model to be incorporated into power flow calculation for the steady state analysis of the power system. SSSC provides controllable compensating voltage, which is in quadrature with the line current, over an capacitive and an inductive range, independently of the magnitude of the line current. This SSSC model is obtained from the injection model for series connected VSC(Voltage Source Converter) by adding a constraint that the injected voltage should be in quadrature with the line current. In this paper the static model is implemented into the continuation power-flow (CPF) program. It is shown that SSSC has its intrinsic superiority over TCSC in controllable power flow range.

• Biomolecules & Therapeutics
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• v.24 no.2
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• pp.147-155
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• 2016

Chaetominine is a quinazoline alkaloid originating from the endophytic fungus Aspergillus fumigatus CY018. In this study, we showed evidence that chaetominine has cytotoxic and apoptotic effects on human leukemia K562 cells and investigated the pathway involved in chaetominine-induced apoptosis in detail. Chaetominine inhibited K562 cell growth, with an $IC_{50}$ value of 35 nM, but showed little inhibitory effect on the growth of human peripheral blood mononuclear cells. The high apoptosis rates, morphological apoptotic features, and DNA fragmentation caused by chaetominine indicated that the cytotoxicity was partially caused by its pro-apoptotic effect. Under chaetominine treatment, the Bax/Bcl-2 ratio was upregulated (from 0.3 to 8), which was followed by a decrease in mitochondrial membrane potential, release of cytochrome c from mitochondria into the cytosol, and stimulation of Apaf-1. Furthermore, activation of caspase-9 and caspase-3, which are the main executers of the apoptotic process, was observed. These results demonstrated that chaetominine induced cell apoptosis via the mitochondrial pathway. Chaetominine inhibited K562 cell growth and induced apoptotic cell death through the intrinsic pathway, which suggests that chaetominine might be a promising therapeutic for leukemia.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.1
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• pp.67.4-67.4
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• 2019

We present preliminary results of our long-term (2009-2017) observing campaign using the NASA IRTF at Mauna Kea, to obtain $2-5{\mu}m$ spectroscopy of ~200 red point sources in the line of sight to the Galactic center. Point sources in our sample were selected from the mid-infrared images of the Spitzer Space telescope, and include candidate massive young stellar objects, which have previously been identified from our Spitzer/IRS spectroscopy. We show high foreground extinction of these sources from deep $3.1{\mu}m$ H2O ice and aliphatic hydrocarbon absorption features, suggesting that they are likely located in the central 300 pc region of the Galactic center. While many sources reveal photospheric $2.3{\mu}m$ gas CO absorption, few of them clearly indicate $3.54{\mu}m$ CH3OH ice absorption, possibly indicating a large dust column density intrinsic to a massive young stellar object.

• Molecules and Cells
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• v.21 no.3
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• pp.428-435
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• 2006

Specific interaction of the epsin N-terminal homology(ENTH) domain with the plasma membrane appears to bridge other related proteins to the specific regions of the membrane that are invaginated to form endocytic vesicles. An additional $\alpha$-helix, referred to as helix 0 (H0), is formed in the presence of the soluble ligand inositol-1,4,5-trisphosphate [$Ins(1,4,5)P_3$] at the N terminus of the ENTH domain (amino acid residues 3-15). The ENTH domain alone and full-length epsin cause tubulation of liposomes made of brain lipids. Thus, it is believed that H0 is membrane-inserted when it is coordinated with the phospholipid phosphatidylinositol-4,5-bisphosphate [$PtdIns(4,5)P_2$], resulting in membrane deformation as well as recruitment of accessory factors to the membrane. However, formation of H0 in a real biological membrane has not been demonstrated. In the present study, the membrane structure of H0 was determined by measurement of electron paramagnetic resonance (EPR) nitroxide accessibility. H0 was located at the phosphate head-group region of the membrane. Moreover, EPR line-shape analysis indicated that no pre-formed H0-like structure were present on normal acidic membranes. $PtdIns(4,5)P_2$ was necessary and sufficient for interaction of the H0 region with the membrane. H0 was stable only in the membrane. In conclusion, the H0 region of the ENTH domain has an intrinsic ability to form H0 in a $PtdIns(4,5)P_2$-containing membrane, perhaps functioning as a sensor of membrane patches enriched with $PtdIns(4,5)P_2$ that will initiate curvature to form endocytic vesicles.

• Journal of Korean Foot and Ankle Society
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• v.28 no.2
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• pp.75-79
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• 2024

Ankle arthrodesis was performed on a 55-year-old male patient with an active lifestyle who developed severe arthritis in the left ankle. Over the follow-up period, high tibial valgization osteotomy was conducted for painful medial knee joint arthritis with genu varum deformity to correct overall lower limb alignment from varus to valgus with respect to the fused ankle. This study was conducted to investigate how hindfoot alignment would change when the overall alignment of the lower limb shifted from varus to valgus with the ipsilateral ankle in a fused state. Conclusively, while no intrinsic changes in the hindfoot alignment were observed following the alteration of lower limb alignment, the hindfoot naturally adjusted to valgus deviation in response to limb valgus realignment. Moreover, symptoms changed in line with this adjustment. Given the absence of similar case studies or reports, a review of relevant literature is included to contribute to knowledge of this subject.

• Journal of the Korean Geotechnical Society
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• v.18 no.4
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• pp.295-307
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• 2002

In the Nakdong River plain a very thick clayey soils are covered widely. Since the early 1990's, some huge reclamation projects have been performed for the development of industrial and residential complexes and so on. Despite a large number of soil investigations have been carried out for the projects, the geotechnical properties have never been elucidated well, so that the settlements of the ground due to the mischaracterized properties were greatly underestimated. Therefore, it has been needed to evaluate definitely the characteristics of the clayey soils, particularly for the compressibility characteristics to help understand the settlement behavior. For the compressibility characteristics of the Pusan clays, physical index and consolidation tests were conducted on the reconstituted and undisturbed samples. Using the result of physical index, the Pusan clays could be divided into two different units, which have different depositional environments. According to the concepts of Burland (1990) and Nagaraj et. al. (1990), the intrinsic state line and field compression curve of the Pusan clays could be established. It could be found from their concepts that the Pusan clays are under the cemented and young normally consolidated state and largely consisted of two units. The cementation of the clays was as well identified by compression index ratio (Tsuchida et. al.,1991) and sensitivity (Leroueil et. al.,1983).