• Journal of Yeungnam Medical Science
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• v.41 no.1
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• pp.13-21
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• 2024

Gene therapy involves the introduction of foreign genetic material into host tissue to alter the expression of genetic products. Gene therapy represents an opportunity to alter the course of various diseases. Hence, genetic products utilizing safe and reliable vectors with improved biotechnology will play a critical role in the treatment of various diseases in the future. This review summarizes various important vectors for gene therapy along with modern techniques for potential craniofacial regeneration using gene therapy. This review also explains current molecular approaches for the management and treatment of cancer using gene therapy. The existing literature was searched to find studies related to gene therapy and its role in craniofacial regeneration and cancer treatment. Various databases such as PubMed, Science Direct, Scopus, Web of Science, and Google Scholar were searched for English language articles using the keywords "gene therapy," "gene therapy in present scenario," "gene therapy in cancer," "gene therapy and vector," "gene therapy in diseases," and "gene therapy and molecular strategies."

• The Journal of Korean Academic Society of Nursing Education
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• v.17 no.3
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• pp.395-404
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• 2011

Purpose: The purpose of this paper was to analyze research papers using movies and to introduce a practical instruction in cinema education for nurse educators in Korea. Method: The computerized database of PubMed, Google scholar, NDSL, CINAHL, and PsychINFO were used to generate relevant literature. Sixteen studies were published between 1990 and 2011 and were included in this review. These papers were analyzed using the matrix method suggested by Garrad (2007). Results: The first paper using movies in nursing education was performed in 1995. There were 16 studies on this issue and classified into one qualitative and 15 quantitative research. Because psychiatric mental health nursing was the main course, movies relating to mental illness were mainly considered. Most papers used questionnaires developed by researchers and discussions regarding the course. The key findings in these papers were all positive. Conclusion: The critics and syntheses in these papers emerged into seven overarching merits of cinema education and that lead to conduct cinema education to deepen students' understanding and to evoke empathy, critical thinking, entertainment, and intimacy. In addition, cinema education was safe and economical. This study recommends discovering suitable films and developments in both instruction process and educational evaluation tools.

• Genomics & Informatics
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• v.8 no.4
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• pp.165-169
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• 2010

The Korean Bioinformation Center (KOBIC) is a national bioinformatics research center in Korea. We developed many bioinformatics algorithms and applications to facilitate the biological interpretation of OMICS data. Here we present an introduction to major bioinformatics resources of databases and tools developed at KOBIC. These resources are classified into three main fields: genome, proteome, and literature. In the genomic resources, we constructed several pipelines for next generation sequencing (NGS) data processing and developed analysis algorithms and web-based database servers including miRGator, ESTpass, and CleanEST. We also built integrated databases and servers for microarray expression data such as MDCDP. As for the proteome data, VnD database, WDAC, Localizome, and CHARMM_HM web servers are available for various purposes. We constructed IntoPub server and Patome database in the literature field. We continue constructing and maintaining the bioinformatics infrastructure and developing algorithms.

• Journal of Broadcast Engineering
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• v.6 no.1
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• pp.58-65
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• 2001

This paper describes a new watermarking attach algorithm, a screen mark attack. The screen mark attack is a modified overmarking attach, which attacks a watermarking system by Inserting another watermark into a marked Image. Overmarking attack has a problem that it cannot be applied to a public watermarking software that prohibits the watermark embedder from embedding another watermark Into an already marked image. However, the proposed attack algorithm can be applied to such a pub1ic watermarking scheme. Test results show that the proposed watermarking attack algorithm is successful for commercial watermarking softwares and attacked images show better quality than Images attached by 07her attack tools.

• Perspectives in Nursing Science
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• v.17 no.2
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• pp.80-89
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• 2020

Purpose: The aim of this study is to review literature on anger management intervention programs for parents published over the last 10 years and to extract the key elements of the interventions through an integrative review. Methods: This research was carried out in stages following Whittemore and Knafl's integrative literature methodology. Key words in Korean and English were used to search the PubMed, MEDLINE, EMbase, CINAHL, RISS, KISS and National Assembly Library databases. Several intervention factors were extracted from the selected papers on the basis of the framework which was helpful to identify the intervention patterns and were classified into meaningful themes. Results: The extracted intervention factors from the final nine studies classified into four themes: 1) Modifying irrational beliefs through cognitive approaches, 2) Empowering parenting competencies through learning a parent's role, 3) Utilizing emotion management skills, and 4) Parent-child relationship improvement training based on self-reflection. Conclusion: Four main themes were drawn from the key components of the various interventions. These findings should be considered in practice, and further intervention development studies for parents using these findings should be conducted.

• Research in Community and Public Health Nursing
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• v.32 no.1
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• pp.24-39
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• 2021

Purpose: This study was to review the previous studies on the 'Willingness to Pay (WTP)' for healthcare services and suggest future implications for nursing research. Methods: Using the scoping review method, we used RISS, KISS, KMbase, Koreamed, PubMed, EMbase, CINAHL as searching engines. According to the selection and exclusion criteria, 40 appropriate studies were selected and analyzed. Results: 24 studies were categorized into medical service field among medical, public health, and nursing service fields. A total of 16 studies were related to healthcare system (policies), 13 studies were to the healthcare intervention, and 11 studies were categorized into the health management. Most of the methods for eliciting WTP (70%) were about a contingent valuation method (CVM), and the use of double bounded dichotomous choice (DBDC) tended to increase. In the nursing field, five WTP studies were identified: two studies published in the early years of 2000, which were conducted on hospital-based home health visit services. Recent studies were mostly about counseling and education by advanced practice nurses (APNs). Conclusion: WTP studies on healthcare services were largely published from the medical fields and health policy areas with the CVM method. In the field of nursing, studies have been conducted on the subject of limited service areas. More active exploration of research topics is required, particularly under the current policy setting, where discussion of the public health insurance fee for nursing practice is essential.

• The Journal of Industrial Distribution & Business
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• v.14 no.11
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• pp.11-18
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• 2023

Purpose: This study aims to respond to essential queries regarding significant impacts the Korean Wave had on the music business especially in light of K-pop's explosive growth on the international scene and how to transform Hallyu into the global dynamics of the music business. Also, the study investigates what degree of cultural bridging through Music's universal language has Kpop achieved beyond its status as a purely musical genre. Research design, data and methodology: For the process of data collecting, the current investigators used a combination of keywords and controlled vocabulary terms to conduct in-depth searches across reputable academic databases, including PubMed, Scopus, Web of Science, and Google Scholar. Keywords are significant in searching databases such that the desired articles can be sought out wiith the keywords "Korean Wave," "Hallyu," and "music industry,". Results: The investigators found the globalization of K-pop, diverse audience engagement, digital transformation, and cultural exchange through Music as four critical effects of the Korean Wave on the music business. Conclusions: Lastly, this study concludes that As we end our investigation into Hallyu's effects on the music business, it is clear that Korean Music's cultural impact and international appeal have created new opportunities and particular difficulties for both professionals and artists.

• Restorative Dentistry and Endodontics
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• v.49 no.1
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• pp.1.1-1.18
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• 2024

The implementation of imaging methods that enable sensitive and specific observation of anatomical structures has been a constant in the evolution of endodontic therapy. Cone-beam computed tomography (CBCT) enables 3-dimensional (3D) spatial anatomical navigation in the 3 volumetric planes (sagittal, coronal and axial) which translates into great accuracy for the identification of endodontic pathologies/conditions. CBCT interpretation consists of 2 main components: (i) the generation of specific tasks of the image and (ii) the subsequent interpretation report. A systematic and reproducible method to review CBCT scans can improve the accuracy of the interpretation process, translating into greater precision in terms of diagnosis and planning of endodontic clinical procedures. MEDLINE (PubMed), Web of Science, Google Scholar, Embase and Scopus were searched from inception to March 2023. This narrative review addresses the theoretical concepts, elements of interpretation and applications of the CBCT scan in endodontics. In addition, the contents and rationale for reporting 3D endodontic imaging are discussed.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.1
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• pp.561-571
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• 2016

Purpose: This study reviewed the innovative educational strategies that have been implemented successfully in US baccalaureate nursing education programs to facilitate appropriate attitudes about caring for older adults. Methods: The data were collected through a search of PubMed and CINAHL using the key words, gerontological or geriatric, attitudes about aging or older people, baccalaureate or undergraduate nursing education or curriculum. Results: The successful strategies are categorized as follows: 1) a multidisciplinary approach integrating aging issues and gerontological contents into diverse nursing courses, 2) active participation of community-dwelling healthy older individuals as an educational mentor, 3) use of audiovisual materials to investigate the misconceptions and attitudes about aging, and 4) discussion through critical thinking and self-reflection toward aging. Implications: For the interdisciplinary approach within nursing courses, it is essential to derive the key contents for gerontological nursing applicable to integration into diverse nursing courses. In addition, it is necessary to provide administrative support for implementing innovative strategies and constructing consistent partnerships with the community for active participation of the elderly as a mentor. Lastly, recognizing the significance of educational strategies for enhancing desirable attitudes toward gerontological nursing and supporting the development of educational capability of a faculty are key issues.

• Journal of Radiation Protection and Research
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• v.9 no.2
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• pp.76-89
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• 1984

Weighted committed dose equivalents($W_T\;H_{50}$) per intake of unit activity of four nuclides-I-131, I-133, Cs-134 and Cs-137-, which was based on the concepts of ICRP Pub. 30, are calculated for adult who is 70 kg and 25 years old and, for infant who is 10 kg and 1 year old. Metabolism of iodine taken through oral or inhalation pathway is described by using the three-compartment model which consists of inorganic, thyroid and organic compartment. After intake, the amount of iodine in every compartment is calculated by solving the transfer equations among the these compartments. As soon as caesium is taken into the body, it is distributed uniformly in the body through the transfer compartment. In this case, the amount of caesium in total body is calculated by using the total body compartment model which is divided into two tissue compartments because of their different biological half-lifes of caesium in body. As a result of calculations, whether oral or inhalation pathway, the values of ($W_T\;H_{50}$) per intake of unit activity of I-131 for infants are about ten times as much as those of adults. On the other hand, for Cs-134 and Cs-137, the values of $W_T\;H_{50}$ per intake of unit activity show that, whether adults of infants, they have almost the same values.