• Title/Summary/Keyword: International Co-production

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Fault Detection, Diagnosis, and Optimization of Wafer Manufacturing Processes utilizing Knowledge Creation

  • Bae Hyeon;Kim Sung-Shin;Woo Kwang-Bang;May Gary S.;Lee Duk-Kwon
    • International Journal of Control, Automation, and Systems
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    • v.4 no.3
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    • pp.372-381
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    • 2006
  • The purpose of this study was to develop a process management system to manage ingot fabrication and improve ingot quality. The ingot is the first manufactured material of wafers. Trace parameters were collected on-line but measurement parameters were measured by sampling inspection. The quality parameters were applied to evaluate the quality. Therefore, preprocessing was necessary to extract useful information from the quality data. First, statistical methods were used for data generation. Then, modeling was performed, using the generated data, to improve the performance of the models. The function of the models is to predict the quality corresponding to control parameters. Secondly, rule extraction was performed to find the relation between the production quality and control conditions. The extracted rules can give important information concerning how to handle the process correctly. The dynamic polynomial neural network (DPNN) and decision tree were applied for data modeling and rule extraction, respectively, from the ingot fabrication data.

Purification and Characterization of Oxidase Induced from Thiobacillus neapolitanus R-10 (Thiobacillus neapolitanus R-10으로 부터 산화 효소의 분리 정제와 특성)

  • Weon, Yong-Don;Kim, Dong-Suck;Ryu, Beung-Ho
    • Journal of Environmental Science International
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    • v.5 no.1
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    • pp.43-50
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    • 1996
  • Thiobacillus neopolitanus R-10, which produces a active thiosulfate oxidase was isolated from nightsoil. The optimal culture conditions of Thiobacillus neopolitanus R-10 for the production of enzyme was determined as followed: 0.8% $Na_2S_2O_3$, 0.2% $KH_2PO_4$, 0.2% $K_2HPO_4$, 0.04% $Na_2CO_3$, 0.02% $MgSO_4$.$7H_2O$, 2ml trace elements solution, ann PH 6.5 at 3$0^{\circ}C$ and 72hr cultivation. The oxidase was successively purified 83 folds yield by ${(NH_2)}_2SO_4$ fractionation, DEAE-Cellulose, Sephadex A-50 column chromatogrophy and gel Sephadex G-150 gel filteration with yield of 5.9%. The molecular weight of purified enzyme was estimated to be 43.000 dalton by SDS-polyacrylamide gel electrophoresis and gel filteration column chromatography The enzyme activity was highest at 40t and PH 7.0 The enzyme activity was relatively high by $\beta$-mercaptoethanol but strongly inhibited by cysteine.

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The Inhibiton Effects of Hypercholesterolemia and Platelet in Fermented and Non-Fermented Preparation of Garlic

  • Kim, Hyun-Kyoung
    • International Journal of Internet, Broadcasting and Communication
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    • v.11 no.4
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    • pp.1-10
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    • 2019
  • This Dietary cholesterol augments lipid profile and primes production and activation of platelets, leading to development of atherosclerosis which produce several detrimental effects on cardiovascular health. Ethnomedicine and Mediterranean diet are natural sources and cost effective modes against several ailments including cardiovascular diseases while fermented foods have gained interest due to their increased nutrient profile, enhanced bioavailability and efficacy. Garlic has been known to reduce cholesterol and inhibit platelet activation. We examined whether fermented garlic ameliorates effects of hypercholesterolemia and platelet functions in rats. Methodology: Male SD rats were fed with hypercholesterolemia diet and treated with spirulina, fermented and non-fermented preparations of garlic for one month. Platelet aggregation and granule secretion were assessed to evaluate platelet activation. Liver and kidney weights, lipid and enzymatic profile of serum and whole blood analysis was performed. Expressions of SREBP, ACAT-2 and HMG-CoA were assessed using RT-PCR while liver and adipose tissues were analyzed for histological changes. Both fermented and non-fermented garlic inhibited platelet aggregation and granule secretion while fermented garlic showed greater inhibitor tendency. Fermented garlic significantly reduced liver weight and triglycerides concentrations than non-fermented garlic. Similarly, fermented garlic greatly abrogated the detrimental effects of steatosis on liver and adipose tissues. Fermented garlic significantly improved lipid profile and modulated platelet functions, thereby inhibiting atherosclerosis and platelet related cardiovascular disorders.

A Study on the Factors Influencing the Purchase of Electric Vehicles

  • Kim, Sung Young;Kang, Min Jung
    • International Journal of Internet, Broadcasting and Communication
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    • v.14 no.1
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    • pp.194-200
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    • 2022
  • As of 2020, the cumulative number of electric vehicles worldwide increased 43% from 2019, exceeding 10 million. We surveyed and analyzed important factors when purchasing electric vehicles for consumers who own electric vehicles. Through this, we tried to find an effective way to supply electric vehicles in the future. The purpose of this study is to present customized marketing proposals for companies by empirically analyzing the factors affecting consumers' electric vehicle purchases and deriving market demands for electric vehicles. We identified the market status of electric vehicles through literature research and reviewed previous studies on the factors affecting the purchase intention of electric vehicles. Through empirical studies, differences in electric vehicle purchase factors according to gender, age, and the degree of importance of performance were analyzed. To this end, the SPSS statistics package was used. Factors influencing the purchase of electric vehicles were set to mileage, charging time, new technology, degree of driving autonomous development, design, price, infrastructure for charging, the phase of maintenance and repair, by the government and local governments. In addition, the most important factors were derived, and the average difference analysis was conducted according to gender, age, and performance importance.

AN ASSESSMENT SYSTEM OF ECO-FRIENDLINESS OF CONSTRUCTED FACILITY IN THE DESIGN PHASE USING VALUE ENGINEERING

  • Byung-Soo, Kim;Dong-Eun, Lee;Suk-Hyun, Kwon;Min-Kwon, Choe
    • International conference on construction engineering and project management
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    • 2009.05a
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    • pp.1625-1629
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    • 2009
  • The new paradigm called 'Low Carbon Green Growth' involved in reducing greenhouse gas is on the rise as a critical issue worldwide. The essential of Kyoto protocol issued in 1997 is to achieve the sustainable economic growth environments by converting existing production system to eco-friendly one. The protocol imposes the liability to reduce greenhouse gas to the countries joined to it. The paradigm is directly involved in the energy consumption and environmental pollution caused by construction activities. Value Engineering which are mainly applied in the design phase in practice is a measure to improve the value of a constructed facility by analyzing and/or appraising the functions and costs of it. However, an appropriate method which assesses eco-friendliness of constructed facility has not been propose by researchers. This paper proposes a method which assesses the performance involved in eco-friendliness of constructed facility using Value Engineering (VE) in the design phase. The method estimates the environmental cost relative to the amounts of energy consumption and environmental pollution occurred over the entire project life cycle. The database called "Life Cycle Inventory DB", which stores information about the amounts of environmental pollution, is used. The algorithm which retrieves the amounts of environmental pollutions from the DB and converts them into environmental costs is developed. The algorithm is implemented into a system which quantifies the eco-friendliness of constructed facility in the design phase using VE.

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Catalytic Technologies for Nitric Acid Plants N2O Emissions Control: In-Duct-Dependent Technological Options (질산제조 플랜트 N2O 제거용 촉매기술: 적용위치별 기술옵션)

  • Kim, Moon-Hyeon
    • Journal of Environmental Science International
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    • v.21 no.1
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    • pp.113-123
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    • 2012
  • A unit emission reduction of nitrous oxide ($N_2O$) from anthropogenic sources is equivalent to a 310-unit $CO_2$ emission reduction because the $N_2O$ has the global warming potential (GWP) of 310. This greatly promoted very active development and commercialization of catalysts to control $N_2O$ emissions from large-scale stationary sources, representatively nitric acid production plants, and numerous catalytic systems have been proposed for the $N_2O$ reduction to date and here designated to Options A to C with respect to in-duct-application scenarios. Whether or not these Options are suitable for $N_2O$ emissions control in nitric acid industries is primarily determined by positions of them being operated in nitric acid plants, which is mainly due to the difference in gas temperatures, compositions and pressures. The Option A being installed in the $NH_3$ oxidation reactor requires catalysts that have very strong thermal stability and high selectivity, while the Option B technologies are operated between the $NO_2$ absorption column and the gas expander and catalysts with medium thermal stability, good water tolerance and strong hydrothermal stability are applicable for this option. Catalysts for the Option C, that is positioned after the gas expander thereby having the lowest gas temperatures and pressure, should possess high de$N_2O$ performance and excellent water tolerance under such conditions. Consequently, each de$N_2O$ technology has different opportunities in nitric acid production plants and the best solution needs to be chosen considering the process requirements.

Induction of Bone Morphogenetic Protein-2 from Gingival Epithelial Cells by Oral Bacteria

  • Kim, Young-Sook;Ji, Suk;Jung, Hong-Moon;Woo, Kyung-Mi;Choi, Young-Nim
    • International Journal of Oral Biology
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    • v.32 no.3
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    • pp.103-107
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    • 2007
  • We hypothesized that plaque-associated bacteria may have a role in maintenance of alveolar bone. To test it, immortalized gingival epithelial HOK-16B cells were co-cultured with live or lysed eight plaque bacterial species and the expression levels of bone morphogenetic protein (BMP)-2 and -4 were examined by real time reverse transcription-polymerase chain reaction. Un-stimulated HOK-16B cells expressed both BMP-2 and -4. Co-culture with plaque bacterial lysates had significant effects on the level of BMP-2 but not on that of BMP-4. Five species including Streptococcus sanguinis, S. gordonii, Veillonella atypica, Porphyromonas gingivalis, and Treponema denticola substantially up-regulated the level of BMP-2. In contrary to the upregulatory effect of lysate, live T. denticola suppressed the expression of BMP-2. In addition, in vitro osteoblastic differentiation assay using C2C12 cells and the conditioned medium of HOK-16B cells confirmed the production of BMPs by gingival epithelial cells and the modulation of BMP expression by the lysates of S. sanguinis and T. denticola. In conclusion, we have shown that plaque bacteria can regulate the expression of BMP-2 by gingival epithelial cells, the physiologic meaning of which needs further investigation.

Effect of the Ethanol Extract of Propolis on Formation of Streptococcus mutans Biofilm

  • Park, Bog-Im;Jung, Yeon-Woo;Kim, Young-Hoi;Lee, Sang-Moo;Kwon, Lee-Seong;Kim, Kang-Ju;An, So-Youn;Choi, Na-Young;You, Yong-Ouk
    • International Journal of Oral Biology
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    • v.41 no.4
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    • pp.253-262
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    • 2016
  • Streptococcus mutans (S. mutans) is one of the most important bacteria in the formation of dental plaque and dental caries. S. mutans adheres to an acquired pellicle formed on the tooth surface, and aggregates with many oral bacteria. It initiates plaque formation by synthesizing glucan from sucrose, which is catalyzed by glucosyltransferases. Propolis is a resinous mixture produced by honeybees, by mixing saliva and beeswax with secretions gathered from wood sap and flower pollen. Bees prevent pathogenic invasions by coating the propolis to the outer and inner surface of the honeycomb. Propolis has traditionally been used for the treatment of allergic rhinitis, asthma and dermatitis. We investigated the inhibitory effects of propolis ethanol extract on biofilm formation and gene expression of S. mutans. The biofilm formation of S. mutans was determined by scanning electron microscopy (SEM) and safranin staining. We observed that the extract of propolis had an inhibitory effect on the formation of S. mutans biofilms at concentrations higher than 0.2 mg/ml. Real-time PCR analysis showed that the gene expression of biofilm formation, such as gbpB, spaP, brpA, relA and vicR of S. mutans, was significantly decreased in a dose dependent manner. The ethanol extract of propolis showed concentration dependent growth inhibition of S. mutans, and significant inhibition of acid production at concentrations of 0.025, 0.05, 0.1 and 0.2 mg/ml, compared to the control group. These results suggest that the ethanol extract of propolis inhibits gene expression related to biofilm formation in S. mutans.

A Study on Engineering Characteristics of Asphalt Concrete Mixtures Using Filler with Recycled Waste Lime (부산석회를 채움재로 재활용한 아스팔트 혼합물의 공학적 특성)

  • Hwang, Sung-Do;Park, Hee-Mun
    • International Journal of Highway Engineering
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    • v.7 no.3 s.25
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    • pp.71-78
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    • 2005
  • This study focuses on finding out engineering characteristics of asphalt concrete mixtures using mineral fillers with recycled waste lime, which is a by-product in the Soda Ash(Na2CO3) production course. The materials tested in this study were made with 25%, 50%, 75% and 100% of mixing ratio based on the conventional mineral filler ratio to analyze the recycle possibility of the waste lime. The asphalt concrete mixtures with recycled waste lime and hydrated lime, and conventional asphalt concrete mixtures were evaluated through their fundamental engineering properties such as Marshall stability, indirect tensile strength, resilient modulus, permanent deformation characteristics, moisture susceptibility and fatigue resistance. The results indicate that the application of recycled waste lime as mineral filler improves the permanent deformation characteristics, stiffness and fatigue endurance of asphalt concrete mixtures at the wide range of temperatures. It is also found that the mixtures with recycled waste lime show higher resistance against stripping than conventional asphalt concrete mixtures. It is concluded from various test results that the waste lime can be used as mineral fillers and especially can greatly improve resistance to permanent deformation of asphalt concrete mixtures at high temperatures.

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EFFECT OF OVER-EXPANSION CYCLE IN A SPARK-IGNITION ENGINE USING LATE-CLOSING OF INTAKE VALVE AND ITS THERMODYNAMIC CONSIDERATION OF THE MECHANISM

  • Shiga, S.;Hirooka, Y.;Miyashita, Y.;Yagi, S.;Machacon, H.T.C.;Karasawa, T.;Nakamura, H.
    • International Journal of Automotive Technology
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    • v.2 no.1
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    • pp.1-7
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    • 2001
  • This paper presents further investigation into the effect of over-expansion cycle in a spark-ignition engine. On the basis of the results obtained in previous studies, several combinations of late-closing (LC) of intake valve and expansion ratio were tested using a single-cylinder production engine. A large volume of intake capacity was inserted into the intake manifold to simulate multi-cylinder engines. With the large capacity volume, LC can decrease the pumping loss and then increase the mechanical efficiency. Increasing the expansion ratio from 11 to 23.9 with LC application can produce about 13% improvement of thermal efficiency which was suggested to be caused by the increased cycle efficiency. The decrease of compression ratio from 11 to 5.5 gives little effect on the thermal efficiency if the expansion ratio could be kept constant. Thus, the expansion ratio is revealed to be a determining factor for cycle efficiency, while compression ratio is no more important, which suggests the usefulness of controlling the intake charge with intake valve closure timing. These were successfully explained by simple thermodynamic calculation and thus the mechanism could be verified by the estimation.

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