• 제목/요약/키워드: International Co-production

검색결과 198건 처리시간 0.026초

Dudleya brittonii extract promotes survival rate and M2-like metabolic change in porcine 3D4/31 alveolar macrophages

  • Kim, Hyungkuen;Jeon, Eek Hyung;Park, Byung-Chul;Kim, Sung-Jo
    • Asian-Australasian Journal of Animal Sciences
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    • 제32권11호
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    • pp.1789-1800
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    • 2019
  • Objective: Although alveolar macrophages play a key role in the respiratory immunity of livestock, studies on the mechanism of differentiation and survival of alveolar macrophages are lacking. Therefore, we undertook to investigate changes in the lipid metabolism and survival rate, using 3D4/31 macrophages and Dudleya brittonii which has been used as a traditional asthma treatment. Methods: 3D4/31 macrophages were used as the in vitro porcine alveolar macrophages model. The cells were activated by exposure to phorbol 12-myristate 13-acetate (PMA). Dudleya brittonii extraction was performed with distilled water. For evaluating the cell survival rate, we performed the water-soluble tetrazolium salt cell viability assay and growth curve analysis. To confirm cell death, cell cycle and intracellular reactive oxygen species (ROS) levels were measured using flow cytometric analysis by applying fluorescence dye dichlorofluorescein diacetate and propidium iodide. Furthermore, we also evaluated cellular lipid accumulation with oil red O staining, and fatty acid synthesis related genes expression levels using quantitative polymerase chain reaction (qPCR) with SYBR green dye. Glycolysis, fatty acid oxidation, and tricarboxylic acid (TCA) cycle related gene expression levels were measured using qPCR after exposure to Dudleya brittonii extract (DB) for 12 h. Results: The ROS production and cell death were induced by PMA treatment, and exposure to DB reduced the PMA induced downregulation of cell survival. The PMA and DB treatments upregulated the lipid accumulation, with corresponding increase in the acetyl-CoA carboxylase alpha, fatty acid synthase mRNA expressions. DB-PMA co-treatment reduced the glycolysis genes expression, but increased the expressions of fatty acid oxidation and TCA cycle genes. Conclusion: This study provides new insights and directions for further research relating to the immunity of porcine respiratory system, by employing a model based on alveolar macrophages and natural materials.

4행정 대형 디젤엔진의 배기 배출특성에 관한 연구 (A Study on the Emission Characteristics in 4 Stroke Large Propulsion Diesel Engine)

  • 김현규;전충환;장영준
    • 한국자동차공학회논문집
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    • 제9권5호
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    • pp.38-45
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    • 2001
  • Environmental protection on the ocean has been interested and nowadays the International maritime organization(IMO) has advanced on the prevention of air pollution from ships. This study presents the emission characteristics of 4 stroke propulsion diesel engine in E2 cycle (constant speed) and E3 cycle (propeller curved speed). Also the effects of important operating parameters in terms of intake air pressure and temperature, and maximum combustion pressure are described on the specific emissions. Emissions measurement and calculation are processed according to IMO technical code. The results show that NOx emission level in E3 cycle is higher than E2 cycle due to lower engine speed and lower maximum combustion pressure by retarding fuel injection timing. Intake air temperature has strong influence on NOx emission production. And CO, HC emissions are not affected by maximum combustion pressure and intake air pressure and temperature.

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디지털 선박생산화를 위한 생산정보기술 (The State-of-the-Art Review on the Information Technologies for Manufacturing Toward Digital Shipbuilding)

  • 이경호;장윤석
    • 한국해양공학회지
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    • 제17권4호
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    • pp.81-85
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    • 2003
  • The industry has undergone a significant change over the last decade: digital business has become a strategy to survive; the extended enterprise is being implemented; parts are made where conditions are most favourable; non-core activities are out-sourced; advanced manufacturing systems and information technologies are introduced to improve manufacturing performance. Suppliers and distributors become part of the supply chain and they all comprise an integrated international co-operative network to provide manufactured goods and support services for a world market just in time, at low prices and with quality surpassing customers' expectations. In this paper, we review various state-of-the-art information technologies for the shipbuilding industry. The successful introduction and implementation of those technologies will be the key enabler for e-transformation in the shipbuilding industry.

Development of Desk for Public Reading in Library

  • Kang, Myung-Sun;Chang, Yub
    • 한국가구학회지
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    • 제19권6호
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    • pp.428-438
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    • 2008
  • Through this study, I developed a new-styled desk for public reading in library in consideration of the characteristics of the company "KIFURS Co., Ltd." established and branded by a part of the members of the association 'Gyeonggi-Incheon Furniture Industry Cooperative', in the background of growing library-furniture market situation according to the government policy and the related participations of competitive companies. The differentially designed product was herein presented by introducing the function of office furniture and related material, by giving the existing product some improvements on the basis of the domestic and international data searching. The characteristic of the developed product is that the basic structure of the desk for public reading is easy to assemble & disassemble and also variable to be extended & modified. This basic structure is available to be mass production and to be pricewise through using aluminum. Furthermore it can be used as other library-furniture and office furniture, too. Also the luxury image was pursued by modern shape and different material, unlike the existing library-furniture.

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A Decision Tree Approach for Identifying Defective Products in the Manufacturing Process

  • Choi, Sungsu;Battulga, Lkhagvadorj;Nasridinov, Aziz;Yoo, Kwan-Hee
    • International Journal of Contents
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    • 제13권2호
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    • pp.57-65
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    • 2017
  • Recently, due to the significance of Industry 4.0, the manufacturing industry is developing globally. Conventionally, the manufacturing industry generates a large volume of data that is often related to process, line and products. In this paper, we analyzed causes of defective products in the manufacturing process using the decision tree technique, that is a well-known technique used in data mining. We used data collected from the domestic manufacturing industry that includes Manufacturing Execution System (MES), Point of Production (POP), equipment data accumulated directly in equipment, in-process/external air-conditioning sensors and static electricity. We propose to implement a model using C4.5 decision tree algorithm. Specifically, the proposed decision tree model is modeled based on components of a specific part. We propose to identify the state of products, where the defect occurred and compare it with the generated decision tree model to determine the cause of the defect.

국내 비철금속 산업부문 온실가스 발생량 산정 방법에 관연 연구 (A Study on the Calculation Method about Emissions of Greenhouse Gases of Nonferrous-metal Industry Part in Domestic Nonferrous-metal Industry)

  • 정진도;한종민;김장우
    • 한국환경과학회지
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    • 제18권2호
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    • pp.197-203
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    • 2009
  • The aim of this study is to calculate process emission of GHGs(greenhouse gases) in nonferrous-metal industry, such as Zn, Pb, Cu and Ni. In addition, variation and emission of GHGs generated from these company were defined. And then, GHGs algorithm and calculation formular which were considered as production process in each part of nonferrous-metal industry were developed to develop calculation program of GHGs emission. These algorithm and calculation formular would present fundamental direction about other nonferrous-metal industry in the future.

Diagnosing the Condition of Air-conditioning Compressors by Analyzing the Waveform of the Raw AE Signal

  • Kim Jeon-Ha;Lee Gam-Gyu;Kang Ik-Soo;Kang Myung-Chang;Kim Jeong-Suk
    • International Journal of Precision Engineering and Manufacturing
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    • 제7권3호
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    • pp.14-17
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    • 2006
  • To diagnosis abnormal compressor conditions in an air-conditioner, the acoustic emission (AE) signal, which is derived from wear condition, compressed air, and assembly error, was analyzed experimentally. Burst and continuous type AE signals resulted from metal contact and compressed air, and the raw AE signal of compressors was acquired in the production line. After extracting samples using waveforms, the Early Life Test (ELT) was conducted and the waveform was classified as normal or abnormal. Efficient parameters in the waveform pattern were investigated in time and frequency domains and a diagnosis algorithm for air-conditioners using Neural Network estimation is suggested.

코르크담체를 이용한 유기휘발성화합물의 제거 (Characterization of Cork Biofilter)

  • 권성현
    • 한국환경과학회지
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    • 제11권12호
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    • pp.1327-1331
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    • 2002
  • The cork have been preferred over the conventional materials, zeolite, ceramics, and lignite as a biofilter medium. During the 6 months of operation, the performance of the cork biofilter was considered good with 150ppm of mixture BTX vapor efficiencies greater than 90% at 60 second of EBCT. It was observed 56 % of removal efficiency under transition conditions at first stage, and then the removal efficiency was increased to above 90 %, and the sustainability of removal efficiency was maintained. At second stage, the performance of cork biofilter was not decreased 90 % efficiency with 150 ppm BTX at 30 sec. EBCT. The production of $CO_2$ due to microbial respiration was increased to the 40 % on the operation of cork biofilter.

Classification of Geared Motor Noise Using a Cepstrum and Comb Lifter Analysis

  • Lee, Min-Hwan;Kang, Dong-Bae;Kim, Hwa-Young;Ahn, Jung-Hwan
    • International Journal of Precision Engineering and Manufacturing
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    • 제8권3호
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    • pp.45-49
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    • 2007
  • A gearing system emits inconsistent noises from the impact of gear teeth when defects are present, but it is not easy for a noise inspector on a production line to distinguish defective products objectively. Since customers constantly complain about various noises from geared motors, it is desirable to devise an analytical technique to classify motors. However, it is difficult to separate inconsistent noises due to defective gears from the overall noise produced by a geared motor using a general signal processing method such as a FFT because low frequency impulse signals have a tendency not to appear in the frequency domain. In this paper, we propose a method that can be used to obtain more objective estimates and measurements of inconsistent noises from a gearing system. The proposed method makes use of the cepstrum domain with an applied autocorrelation and comb lifter, followed by a domain inversion.

A Study on Ice Slurry Production by Water Spray

  • Kim, Byeong-Sun;Lee, Yoon-Pyo;Yoon, Seong-Young;Lee, Jin-Ho
    • International Journal of Air-Conditioning and Refrigeration
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    • 제6권
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    • pp.45-55
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    • 1998
  • A theoretical and experimental study is performed to investigate the characteristics of ice slurry product. By diffusion-controlled evaporation model the possibility of ice slurry is theoretically anticipated. The water vapor evaporated from the surface of droplets is extracted continuously from the chamber by a vacuum pump. The droplet diameter is measured by silicon immersion method. The ice slurry is obtained by spraying droplets of ethylene glycol aqueous solution in the chamber where pressure is maintained under the triple point of water. The droplet with the diameter of 300 $\mu\textrm{m}$and the initial temperature of 2$0^{\circ}C$ was changed into ice particle within the chamber of 1.33m in height.

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