• 대한한의학회지
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• 제36권4호
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• pp.145-149
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• 2015

Objectives: We carried out an observational study of the effects of Nei Guan (P6) and Gong Sun (SP4) acupuncture for the treatment of CINV, preparing for further randomized controlled trial study. This is a case series to explore the changes in the incidence of CINV by acupuncture. Methods: Patients reported a Rhodex index indicating the severity of nausea and vomiting and loss of appetite, before acupuncture, after acupuncture and 1-week follow-up examination. Twelve patients with CINV participated in this study. We included patients receiving chemotherapeutic agents that might induce moderate or severe nausea and vomiting. We conducted 5 treatment sessions with P6 and SP4 acupuncture over the course of 5 days. Results: The median Rhodex score were decreased in 5 patients over time, while we observed loss of appetite of 6 patients were improved over time. During the study, the mean of Rhodex of total patients revealed a decrease of Day 1, Day 7, Day 14; 0.74, 0.68, 0.38, respectively, while the mean of loss of appetite showed a decrease of Day 1, Day 7, Day 14; 5.25, 4.08, 4.00, respectively. Conclusions: The study gives a preliminary data that manual acupuncture of P6 and SP4 may reduce the severity of CINV and loss of appetite, and justifies further study.

• 대한한방내과학회지
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• 제1권1호
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• pp.44-49
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• 1976

To investigate the effect of Kwi Ryong Tang a precious tonic of herbal drugs, the blood of rabbit was depleted from the heart for the purpose of experiment and the author administered the Kwi Ryong Tang to that rabbit. This effect of the tonic on the experimental groups was Compared with that of the control group and the author observed the following results; 1. In the experimental group treated with Kwi Ryong Tang before the depletion of the blood, the recovery of blood, the recovery of blood loss is some what accelerated that in the control group. 2. In the experimental group treated with Kwi Ryong Tang after the depletion of the blood, the recovery of blood loss is slightly accelerated that in experimental group which was treated with Kwi Ryong Tang before the depletion of the blood. 3. In the experimental group treated with Kwi Ryong Tang before and after the depletion of the blood, the recovery of the blood loss is markedly accelerated Comparing, that in the experimental group which was treated with Kwi Ryong Tang before or after the depletion of the blood loss.

• Tuberculosis and Respiratory Diseases
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• 제64권5호
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• pp.362-368
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• 2008

연구배경: LKB1 (STK11)유전자는 Peutz-Jeghers syndrome에서 생식세포 돌연변이가 있으면 소화기와 폐를 포함한 타 장기의 암 발생 위험도가 증가한다고 알려져 있으며, 또한 종양 억제 기능이 있다고도 알려지고 있다. 하지만 현재까지 폐암에서 LKB1 유전자의 생물학적 기능이 명확하게 밝혀져 있지 않아, 저자들은 폐암조직에서 LKB1 단백질 발현소실과 임상양상 및 조직병리와의 연관관계를 알아보고자 하였다. 방법: 1998년 3월부터 2006년 3월까지 본원에 내원하여 원발성 폐암으로 진단받고 근치적 절제술을 시행 받은 77명의 환자를 대상으로 하였다. 파라핀에 포매된 조직을 택하여 면역조직화학염색법으로 LKB1 단백질 발현을 확인하였고, 정상 기관지 상피세포 세포질에서의 단백질 발현과 비슷한 정도의 발색을 갖는 종양세포가 전체 종양에서 30% 이상인 경우를 양성으로 판정하였다. 결과: LKB1 발현 양성은 40% (31/77)였고, 남성, 흡연, 편평상피암인 경우에 LKB1 발현 음성률이 통계적으로 유의하게 높았다. 종양위치가 중앙부위일수록 LKB1 발현 음성률이 증가하는 경향이 있으며, 종양 위치가 말초 부위인 경우 흡연력이 있는 군에서 LKB1 발현 음성률이 통계적으로 유의하게 높았다. TNM 병기가 진행할수록 LKB1 발현 음성률이 증가하는 경향이 있었으며, T2 병기 이상, N 병기가 진행할수록 LKB1 발현 음성률이 높아지는 경향이 있었으나, 통계적 유의성은 보이지 않았다. 결론: 원발성 폐암환자에서 LKB1 발현소실은 성별, 흡연력, 조직병리 형태와 의미있는 상관관계를 보였으나, 예후인자로서의 의의는 찾지 못했다. 하지만 환자의 숫자가 적어 추후의 연구가 이루어져야 할 것으로 사료된다.

• 대한물리의학회지
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• 제8권4호
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• pp.573-582
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• 2013

PURPOSE: The purpose of this study was to establish the reliability and validity of the Wheelchair User's Shoulder Pain Index (WUSPI), which was translated into Korean for long-term wheelchair users. This index measured 15 functional activities, including transfer, self-care, wheelchair mobility and general activities. METHODS: To assess test-retest reliability, 23 long-term wheelchair users completed this self-administered index twice within the same day. Reliability was determined by the intraclass correlation coefficient (ICC), and Cronbach's alpha was used to measure internal consistency. To examine concurrent validity, 21 long-term wheelchair users completed the questionnaire, and we examined the correlation between the index score and the shoulder range of motion measurements. RESULT: The results showed that the intraclass correlation for test-retest reliability of the total index score ranging from .88 to .99 was good to excellent. Additionally, Cronbach's alpha was .96. The internal consistency indicated excellent. Concurrent validity showed negative correlations of total index score to range of motion measurements of shoulder flexion (rho=-.58), extension (rho=-.09), abduction (rho=-.59), external rotation (rho=-.07) and internal rotation (rho=-.3), suggesting a relationship of total index score to loss of shoulder range of motion. CONCLUSION: The Korean WUSPI shows not only high reliability and internal consistency, but also concurrent validity with loss of shoulder flexion and abduction.

• 한국임상수의학회지
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• 제28권1호
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• pp.139-143
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• 2011

A Spitz (5-years old, castrated male) and a Maltese (9-years old, castrated male) were presented with weight loss, polyuria/polydipsia (PU/PD) and depression. Diabetic ketosis was diagnosed based on clinical signs, physical examinations and screening tests (CBC, serum chemistry and urinalysis). The dogs were treated with NPH initially. However, NPH was inadequate to control blood glucose level due to the short duration of the action (< 5 hours). Because of the poor glycemic control with NPH, the dogs showed diabetic complications including weight loss and cataract. After change to glargine, the duration of insulin action was extended up to 11 hours. As a result, there was significant improvement in clinical signs and serum fructosamine concentrations. This study suggests that glargine is useful as a long-acting insulin in dogs which have poor glycemic control due to the short duration of NPH.

• 한국안전학회지
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• 제36권3호
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• pp.66-73
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• 2021

This report documents the results of an at-power internal events Level 1 Probabilistic Safety Assessment (PSA) for a Korea research reactor (KRR). The aim of the study is to determine the accident sequences, construct an internal level 1 PSA model, and estimate the core damage frequency (CDF). The accident quantification is performed using the AIMS-PSA software version 1.2c along with a fault tree reliability evaluation expert (FTREX) quantification engine. The KRR PSA model is quantified using a cut-off value of 1.0E-15/yr to eliminate the non-effective minimal cut sets (MCSs). The final result indicates a point estimate of 4.55E-06/yr for the overall CDF attributable to internal initiating events in the core damage state for the KRR. Loss of Electric Power (LOEP) is the predominant contributor to the total CDF via a single initiating event (3.68E-6/yr), providing 80.9% of the CDF. The second largest contributor is the beam tube loss of coolant accident (LOCA), which accounts for 9.9% (4.49E-07/yr) of the CDF.

• 한국소음진동공학회논문집
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• 제14권5호
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• pp.370-376
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• 2004

The overall aim of this paper is to determine coupling loss factor of welding point between shell and cylinder using loss factor and structural loss factor. For this purpose, two kinds of loss factor were adopted. One is loss factor of each sub structure, another is structural loss factor based on the complex welded or assembled structure. Using these two parameters, it ispossible to derive the coupling loss factor which represent characteristic condition of SEA theory. Coupling loss factor of conjunction in complex structure was expressed as power balance equation. The derived equation for a coupling loss factor has been simplified on the assumption of one way (uni-directional) power flow between multi-sub structures. Using these conditions, it is possible to find the equation of coupling loss factor expressed as above two loss factors. To check the effectiveness of above equation, this paper used two-stage application. The first approach was application between simple cylinder and shell. The next was adopted rotary compressor. Rotary compressor has three main conjunctions between shell and internal vibration part. This equation was applied to find out the optimum welding point with respect to reduce the noise propagation. It shows the effective tool to evaluate the coupling loss factor in complex structure

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2003년도 춘계학술대회논문집
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• pp.969-972
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• 2003

The overall aim of this paper is to determine coupling loss factor of welding point between shell and cylinder using loss factor and structural loss factor. For this purpose, two kinds of loss factor were adopted. One is loss factor of each sub structure, another is structural loss factor based on the complex welded or assembled structure. Using these two parameters, it is possible to derive the coupling loss factor which represent characteristic condition of SEA theory. Coupling loss factor of conjunction in complex structure was expressed as power balance equation. The derived equation for a coupling loss factor has been simplified on the assumption of one way(nl- directional) power flow between multi-sub structures. Using these conditions, it is possible to find the equation of coupling loss factor expressed as above two loss factors. To check the effectiveness of above equation, this paper used two stage application. The first approach was application between simple cylinder and shell. The next was adopted rotary compressor. Rotary compressor has three main conjunctions between shell and internal vibration part. This equation was applied to find out the optimum welding Point with respect to reduce the noise propagation. It shows the effective tool to evaluate the coupling loss factor in complex structure

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 학술대회 논문집 전문대학교육위원
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• pp.92-95
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• 2004

Power transformer is an important apparatus in transforming and delivering the power in a power system. It shows less accident ratio than other system apparatus, but once the accident occurs, it causes long-term operation stoppage and economic loss. It brings high bad spillover effects. Therefore, the role of protective relaying, which is to prevent internal fault a power transformer is highly important. This study proposed advanced algorithm that can clearly determine internal fault of the power transformer and magnetizing inrush, through numerical analysis by using the terminal voltage and input output current.

• 대한핵의학회지
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• 제4권2호
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• pp.55-66
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• 1970

Reappraisal measurements of apparent half survival time of red cell by $^{51}Cr$ method was made and effects of blood-letting over red cell survival were observed. The study was performed on 53 normal male subjects under three different experimental conditions. 1. Group 1 Mean $^{51}Cr$ red cell half survival by ACD wash method was 29.7 days. $T\frac{1}{2}$ of Ascorbic acid method was 29.0 days in group with 100 mg dose and 29.1 days in group with 50 mg dose respectively. There was no difference between these two methods in regards to red cell half survival. No difference were noted in amount of ascorbic acid administered. 2. Group 2 As daily amount of blood loss is increased the shortening of red cell half survival was noted. Rapid phase was seen when blood loss ranged 10 to 25 ml per day, while slow phase noted when more loss amounted 25 ml or more daily. Thus, it was clear that there was more than an exponential relation between $T\frac{1}{2}$ and the amount of blood loss. 3. Group 3 $T\frac{1}{2}$ measured by cpm per whole blood was within normal range and $T\frac{1}{2}$ measured by cpm per red cell mass showed shortening tendency when compared with the former in the group measured after blood loss (from 25 ml daily up to 100 ml daily in 10 days). In the group with rather constant blood loss of 100 ml daily for 10 consecutive days revealed the significant difference in two measurements (P<0.01). 4. $T\frac{1}{2}$ in non-steady state When red cell production is increased compared with red cell destruction, $T\frac{1}{2}$ measured by cpm per red cell mass being shorter than that by cpm per whole blood. Shortening of $T\frac{1}{2}$ measured by cpm per whole blood is more prominent. if red cell destrction is enhanced and exceeds production. 5. It is clear that when expressing red cell destruction rate, $T\frac{1}{2}$ measured by cpm per whole blood is more adequate and production more consistent with cpm red cell mass. 6. $T\frac{1}{2}$ measured during blood-letting, when corrected by amount of blood loss, it remains normal. It is erroneous to use conventional equational when measuring $T\frac{1}{2}$ in non-steady. $T\frac{1}{2}$ measured by cpm per whole blood is considred more applicable in clinical evaluation.