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혈당 조절이 되지 않는 1형 당뇨병 환자에 대한 한방 치험 1례 (Case Report of Type-1 Diabetes Mellitus with Uncontrolled Blood Sugar Improved by Complex Korean Medicine Treatment)

  • 김수덕;서민조;심현아;정우진;조혜리;공건식;최요섭
    • 대한한방내과학회지
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    • 제44권2호
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    • pp.269-276
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    • 2023
  • Objective: This study reported the effectiveness of Korean medicine for a patient with Type-1 diabetes mellitus after pancreatectomy with a compression fracture of the thoracic spine. Methods: A patient diagnosed with Type-1 diabetes mellitus after a pancreatectomy was treated with acupuncture, pharmacopuncture, Gami-hwanggigyejiomul-tang (modified Huangqi Guizhi Wuwu decotion), Jindang-won, etc. The conventional treatment was maintained using an insulin pump and insulin injection. Results: Blood glucose (FBS/PP2hrs), ESR and CRP decreased after one month of treatment. Conclusion: Gami-hwanggigyejiomul-tang and Jindang-won may be effective treatments for Type-1 diabetes mellitus. Further studies are needed to confirm the findings of this case.

한국인에서 획득한 Helicobacter pylori의 CagA에 존재하는 SHP-2 binding site의 분석 (Analysis of the SHP-2 Binding Site of Helicobacter pylori CagA Protein in Korean)

  • 조지윤;정진용;강호영;김군도;변정식;명승재;정훈용;양석균;홍원선;김진호;이진혁
    • 생명과학회지
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    • 제15권6호
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    • pp.904-908
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    • 2005
  • 최근에 발표된 연구 결과에 의하면 pylori CagA내에 존재하는 SHP-2 binding site의 아미노산 서열을 분석한 후, 특정 서열이 위선암의 발병과 연관되어 있다고 보고하였다. 그러나 한국인을 대상으로 CagA 내 에 존재하는 SHP-2 binding site아미노산 서열의 특성을 밝힌 연구는 없다. 따라서 본 연구는 한국인에서 획득한 H. pylori의 CagA SHP-2 binding site에 대해 아미노산 서열을 분석하여 그 특성을 알아보고자 하였다. 총 62 균주의 H. pylori 를 분석한 결과 환자의 질환과 관계없이 모든 H. pylori 균주에서 East Asian (A-B상 혹은 A-B-B-D)을 보여주었다. 일본과 더불어 한국은 위선암 유병률이 높은 나라이므로, 연구 대상의 모든 한국인에서 East Asian type CagA를 가진 H. pylori가 발견된 것이 위선암 유병률과 연관될 가능이 높아 보인다. 그러나 H. pylori의 발병 기전을 보다 더 명확히 이해하기 위해서는 보다 많은 국가와 지역을 대상으로 이러한 유전형 조사가 필요할 것 같다.

만성 활동성 B형 간염에서 생간건비탕(生肝健脾湯)으로 혈청 aminotransferase 수치가 저하된 1례 (The rapid recovery of serum aminotransferase in a case of chronic active hepatitis type B treated with Sengangeonbi-tang)

  • 박정미;정우상
    • 대한한방내과학회지
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    • 제21권2호
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    • pp.337-339
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    • 2000
  • Indigestion is one of the most frequent symptom in chronic hepatitis. We treated a 20 year-old female patient of chronic active hepatitis type B with Sengangeonbi-tang. The patient complained indigestion and constipation. The serum aminotransferase were higher and viral marker showed hepatitis was in active phase. 1 week later, the symptom had been changed from severe to mild and aminotransferase decreased. We continued to prescribe the medicine 2 weeks more and could observe that the symptom disappeared and the aminotransferase fell down under normal value with no side effect. Sengangeonbi-tang showed desirable effect on indigestion and more rapid recovery of aminotransferase than previous reports about treating hepatitis.

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스프링식 로프 브레이크의 구조해석 (Structural Analysis of Rope Brake by Spring Type)

  • 이종선
    • 한국공작기계학회논문집
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    • 제14권1호
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    • pp.89-94
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    • 2005
  • The objective of this study is structural analysis of rope brake by spring type. The finite element model was developed to compute the stress, strain and friction force for rope brake by spring type. The ANSYS code was used for this analysis. In order to structural analysis of rope brake, many variables such as internal pressure, boundary condition load condition and constraints were considered.

스프링식 로프 브레이크의 구조해석 (Structural Analysis of Rope Brake by Spring Type)

  • 이종선;원종진
    • 한국공작기계학회:학술대회논문집
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    • 한국공작기계학회 2004년도 추계학술대회 논문집
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    • pp.150-155
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    • 2004
  • The objective of this study is structural analysis of rope brake by spring type. The finite element model was developed to compute the stress, strain and friction force for rope brake by spring type. The ANSYS code was used for this analysis. In order to structural analysis of rope brake, many variables such as internal pressure, boundary condition, load condition and constraints were considered.

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Single Pleural Relapse of a Nasal-Type Extranodal Natural Killer/T-Cell Lymphoma: A Case Report

  • Kim, Keunmo;Oh, Youngmin;Lim, Sung-Nam;Choi, Song-Yi;Lee, Ok-Jun;Choe, Kang-Hyeon;Lee, Ki-Man;An, Jin-Young
    • Tuberculosis and Respiratory Diseases
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    • 제76권4호
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    • pp.184-187
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    • 2014
  • A nasal-type extranodal natural killer/T-cell lymphoma is considered an aggressive form of non-Hodgkin's lymphoma, with approximately half of all patients relapsing during the follow-up period, and most relapses occurring within the first 2 years of remission. Here we report an unusual case of a 42-year-old man who experienced recurrence in single pleura after 8 years of remission.

Case of hyperosmolar hyperglycemic state by a sodium-glucose cotransporter 2 inhibitor

  • Nho, In-Young;Kim, Hae-Sung;Kang, Nam-Kyu;Lee, Myung-Won;Kim, Soo-Kyung;Park, Seok-O
    • 고신대학교 의과대학 학술지
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    • 제33권3호
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    • pp.402-408
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    • 2018
  • Inhibitors of sodium-glucose cotransporters type 2 (SGLT2) are proposed as a novel approach for the management of type 2 diabetes mellitus. SGLT2 cotransporters are responsible for reabsorption of 90 % of the glucose filtered by the kidney. The glucuretic effect resulting from SGLT2 inhibition contributes to reduce hyperglycaemia and also assists weight loss and blood pressure reduction. In this study, we presented the case of a 59-year-old male who developed hyperosmolar hyperglycemic state (HHS), possibly caused by a sodium-glucose cotransporter 2 (SGLT2) inhibitor, a novel class of antihyperglycemic agents. This case highlights that HHS can develop in patients with diabetes treated with SGLT2 inhibitors.

도시 호텔 공용부문에 나타난 내부기능구성형식에 관한 연구 - 한국과 일본의 중규모 특급호텔을 중심으로 - (A Study on the Spatial Configuration of Internal Functions of Public Area in City Hotels - Focusing on middle size first-class hotels in Korea and Japan -)

  • 이창노
    • 한국실내디자인학회논문집
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    • 제13권5호
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    • pp.125-132
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    • 2004
  • The purpose of this study is focused on defining the types of spatial configuration of internal functions in city hotels by researching and analyzing city hotels in Korea and Japan. The scope of this study is limited to the period of early 1980's to the end of 1990's and 18 city hotels in Korea and Japan are selected as subject. Researching existing records and analyzing plans, surveys are used as the method of the study. The result of this study is as follow. First, block composition of floor plans that is used for hotel construction could be divided into three types (immanent type-6hotels, combined type-7hotels, adjacent type-4hotels). Second, the result of analysis about the internal functions and structural types of public area in city hotels is as follow. More Korean city hotels are taking concourse type (Korea 77.8%, Japan 55.6%) and hall type (Korea 22.2%, Japan 11.1%) than Japanese city hotels. However, the mixed type (concourse type +hall type) is only used in Japan (Korea 0%, Japan 33.3%). Third, as the result of the comparison of the size of public area between Korea and Japan, Korean hotels (36.70%) have larger space than Japanese hotels only in the service area. public (Korea 33.98% < Japan 34.71%), business (Korea 27.68% Japan 31.41%)and empty (Korea 1.64% < Japan 6.13%) area is taking larger space in Japanese city hotels than Korean.

단삼이 당뇨병성 신병증 Rat의 신기능 및 조직학적 변화에 미치는 영향 (The Effects of Salvia Miltiorrhiza on Renal Function and Histopathological Changes in Streptozotocin-induced Diabetic Nephropathy Rat Model)

  • 김영석;이병철;안세영;두호경;안영민
    • 대한한방내과학회지
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    • 제29권3호
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    • pp.787-799
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    • 2008
  • Objective : Diabetic nephropathy is the most common cause of end stage renal disease. AGE, $TGF-{\beta}1$ type IV collagen, and macrophage/monocyte infiltration are the main factors of diabetic nephropathy. We investigated the effects of Salvia miltiorrhiza on renal function and histopathological changes in streptozotocin(STZ)-induced diabetic nephropathy rat model. Methods : Diabetes was induced in male Sprague-Dawley rats(290${\pm}$10g) by injecting STZ(45mg/kg) into the tail vein. Rats were divided into 3 groups(n = 6): normal, control, and salvia. After 8 weeks of administration of Salvia miltiorrhiza extract on the Salvia group, we checked 24 hrs urine, blood biochemistry and renal tissue to evaluate renal function and histopathological changes by examining parameters including albuminuria, BUN, creatinine, cholesterol, LDL, TG, macrophage/monocyte antigen(ED-1), $TGF-{\beta}1$, AGE, and type IV collagen. Results : Salvia miltiorrhiza decreased the amount of 24hrs proteinuria, and inhibited histopathological changes of diabetic nephropathy including the expression and accumulation of various factors which could promote development of diabetic nephropathy. Conclusion : These findings suggest that Salvia miltiorrhiza might protect the renal function and inhibit the development of renal injury by regulating factors including AGE, $TGF-{\beta}1$ Type IV collagen, macrophage and monocyte infiltration. So Salvia miltiorrhiza can be used for diabetic patients to prevent the progression of diabetic nephropathy.

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다발성 외상 환자의 대퇴골 간부 골절에서 임시 외고정술 후 내고정술로의 전환 (Conversion to Internal Fixation after Temporary External Fixation for Femoral Shaft Fractures in Polytrauma Patients)

  • 주석규;강경운;김영우;오형근
    • Journal of Trauma and Injury
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    • 제27권4호
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    • pp.151-157
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    • 2014
  • Purpose: We report the surgical outcomes for femoral shaft fractures in polytrauma patients who were temporarily treated with external fixation and subsequently converted to internal fixation. Methods: From August 2008 to April 2012, we enrolled 13 patients with multiple traumas due to high-energy injuries and concurrent femoral shaft fractures in which temporary external fixation was carried out. The mean age was 39 years, with a range from 18 to 55 years. Ten were men and 3 were women. According to the AO/OTA classification of fractures, type A was found in 5 patients, type B in 6, and type C in 2, with open fractures being found in 6 patients and femoral artery rupture occurring in 2. For internal fixation, intramedullary nailing was performed in 7 patients, and minimally-invasive fixation of locking compression plates was used in 6. Results: Of the 7 patients converted to intramedullary nailing, 1 experienced delayed union. Of the 6 patients treated with minimally-invasive plate fixation, delayed union occurred in 5, and an auto-bone graft was performed within, on average, 8 months (range: 5~10 months), leading to bone union in all cases in the final follow-up. None of the patients experienced infections or complications involving other organs after having been converted to internal fixation. During the mean follow-up of 19 months, patients achieved satisfactory functional outcomes. Conclusion: In polytrauma patients with a femoral shaft fracture who have been treated with temporary external fixation and who may need internal fixation due to the occurrence of delayed union, an appropriate internal fixation method needs to be selected based on the patient's physical status, and the fracture type.