• Title/Summary/Keyword: Internal Damage

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Information as An Object of Legal Regulation in Ukraine

  • Iasechko, Svitlana;Ivanovska, Alla;Gudz, Tetyana;Marchuk, Mykola;Venglinskyi, Oleksandr;Tokar, Alla
    • International Journal of Computer Science & Network Security
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    • v.21 no.5
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    • pp.237-242
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    • 2021
  • The article deals with the problematic issues of defining information as an object of private relations. Definitions that they are intangible and non-consumable by nature, are inextricably linked to a specific material carrier are/or secured by the subject that transmits them, messages, and information that have quantitative and qualitative characteristics, and are capable of having a freight or another value, and in case of its illegal usage causing damage and moral harm.

Numerical modeling of internal waves within a coupled analysis framework and their influence on spar platforms

  • Kurup, Nishu V.;Shi, Shan;Jiang, Lei;Kim, M.H.
    • Ocean Systems Engineering
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    • v.5 no.4
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    • pp.261-277
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    • 2015
  • Internal solitary waves occur due to density stratification and are nonlinear in nature. These waves have been observed in many parts of the world including the South China Sea, Andaman Sea and Sulu Sea. Their effect on floating systems has been an emerging field of interest and recent offshore developments in the South China Sea where several offshore oil and gas discoveries are located have confirmed adverse effects including large platform motions and riser system damage. A valid numerical model conforming to the physics of internal waves is implemented in this paper and the effect on a spar platform is studied. The physics of internal waves is modeled by the Korteweg-de Vries (KdV) equation, which has a general solution involving Jacobian elliptical functions. The effects of vertical density stratification are captured by solving the Taylor Goldstein equation. Fully coupled time domain analyses are conducted to estimate the effect of internal waves on a typical truss spar, which is configured to South China Sea development requirements and environmental conditions. The hull, moorings and risers are considered as an integrated system and the platform global motions are analyzed. The study could be useful for future guidance and development of offshore systems in the South China Sea and other areas where the internal wave phenomenon is prominent.

A Case of Chronic Renal Failure Associated with Systemic Capillary Leak Syndrome (전신성 모세혈관 누출 증후군으로 인한 만성 신질환 1예)

  • Baek, Seon Ha;Shin, Nara;Kim, Hyo Jin;Han, Mi Yeun;Choi, Dong-Ju;Bang, Soo-Mee;Kim, Sejoong;Paik, Jin Ho
    • Journal of Yeungnam Medical Science
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    • v.29 no.2
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    • pp.145-149
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    • 2012
  • Systemic capillary leak syndrome (SCLS) is an unusual entity characterized by hypovolemic shock, hemoconcentration, and hypo-albuminemia associated with paraproteinemia as a result of marked capillary hyper-permeability. Complications of this syndrome can include compartment syndromes, pulmonary edema, thrombosis, and acute kidney injury. This paper reports a case of severe SCLS accompanied by acute tubular necrosis caused by hypoperfusion and myoglobinuria secondary to rhabdomyolysis, which resulted in chronic kidney disease that necessitated hemodialysis. However, there have been rare data of residual end-organ damage after acute attacks in Korea. Therefore, this paper reports a case of complicated SCLS enough to hemodialysis and that developed into chronic kidney disease.

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Case Report of Sensory Disturbance with Suspicious Syringomyelia (척수공동증 의증으로 인한 감각장애 환자 치험 1례)

  • Kang, Baek-Gyu;Han, Deok-Jin;Lee, Jung-Wook;Kim, Hoi-Young;Lee, In;Kim, Kang-San;Park, Sang-Moo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.1
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    • pp.246-251
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    • 2008
  • Syringomyelia is a rare disorder that causes a cyst to form in spinal cord. This cyst, called a syrinx, can damage to the spinal cord and cause symptoms such as motor weakness, pain, sensory disturbance, etc. We experienced a case of tactile hypesthesia suspecting syringomyelia in 16 year old male patient. Syringomyelia in T2/3 level was diagnosed by magnetic resonance imaging. Hypesthesia was similar to mamokbulin in oriental medicine. And we assumed these symptoms induced by conditions called kiheo in analyzing patient's symptoms and signs. We treated the patient by acupuncture, herbal medicine improving kiheo, and other methods. In the result, the symptoms had withdrawn. This case suggested possibility to treat syringomyelia in oriental medicine, but single case is insufficient for evidence.

[ $^{99m}Technetium-Heat$ ] Damaged Erythrocyte Spleen Scan ($^{99m}Technetium$-가열처리 적혈구에 의한 비장스캔)

  • Choi, Chang-Woon;Park, Seok-Gun;Chung, June-Key;Lee, Myung-Chul;Cho, Bo-Youn;Koh, Chang-Soon;Chung, Soon-Il
    • The Korean Journal of Nuclear Medicine
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    • v.20 no.1
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    • pp.39-43
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    • 1986
  • [ $^{99m}Technetium-Heat$ ] damaged erythrocyte were used as spleen scanning agents in 12 patients from July, 1985 to April, 1986. We used this scan to evaluate situs inversus, asplenia, accessory spleen, hypersplenism, splenic infarction, tumor staging and evaluation of therapy, especially when the $^{99m}Tc-tin$ colloid scans were not definite for diagnosis. The techniques applied to these scans were in vivo/in vitro-labeling method and heating-method to damage the erythrocytes. Liver-to-spleen uptake ratios were increased upto 100 : 1 and interference from the left lobe of the liver was eliminated. These scans were helpful to evaluate the spleen.

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Two Cases of Acute Lung Injury Caused by Nitrogen Dioxide Inhalation (이산화질소($NO_2$)에 의한 폐손상 치험 2예)

  • Kim, Yeon-Jae;Kim, Seong-Ho;Kim, Su-Dong;Cha, Seung-Ick;Lee, Yeung-Suk;Park, Jae-Yong;Jung, Tae-Hoon
    • Tuberculosis and Respiratory Diseases
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    • v.40 no.4
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    • pp.436-441
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    • 1993
  • Human lung injury caused by the inhalation of nitrogen dioxide($NO_2$) has been reported in occupational situations other than agriculture, including arc welding, production of nitric acid or explosives, and blasting operations. Nitrogen dioxide reacts with the water in the respiratory tract to form nitric acid. The nitrates and nitrites formed from dissociation of nitric acid cause extensive local and systemic tissue damage. We present two cases of acute lung injury due to accidental inhalation of $NO_2$ gas in occupational situtions with a review of the literature.

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Effect of Ginsenosides on Liver Cell Proliferation in Relation to Its Clinical Applicability (임상적 적용과 관련된 간세포 증식에 미치는 Ginsenosides의 효과)

  • Yamamoto Masahiro;Miki Shunji;Deguchi Hitoshi;Ogawa Toshiyuki;Uemiya Masanao;Nakama Satoshi;Uemura Taizo
    • Proceedings of the Ginseng society Conference
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    • 1988.08a
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    • pp.36-38
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    • 1988
  • We have studied the ginsenoside effect on DNA RNA and protein synthesis in bone marrow. Ginseng was found to have a beneficial effect on ${\alpha}-napthyl-isothio-cyanate-induced$ hepatobiliary damage. Stimulatory effects of some ginsenosides were shown for cell proliferation and DNA synthesis in a culture liver cell line. The clinical applicability of ginseng on liver diseases will be discussed in relation to traditional medicine.

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Hepatoprotective Effects of GongJin-dan, on Ethanol-mediated Experimental Liver Damage in Rats

  • Hur, Hyun;Kim, Hee-Jun;Park, Kyung;Kwak, Min-A;Kim, Dae-Jun;Byun, Joon-Seok
    • The Journal of Internal Korean Medicine
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    • v.29 no.4
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    • pp.1037-1047
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    • 2008
  • Background : A traditional Oriental medicine, GongJjn-dan (GJD), is one of the most well-known tonic agents in Korea. Among 6 types of GJD components, antler, red ginseng, and Cornus fructus have shown antioxidant effects, while EtOH-induced tissue damage may be a consequence of oxidative stress. Objectives & Methods : The hepatoprotective effects of GJD were evaluated on EtOH-mediated experimental liver damaged rats at 50, 100, 250 and 500mg/kg comparing with 100mg/kg of silymarin as a reference drug in the present study. Test substances were dosed once a day for 60 days with oral administration of 20% ethanol 2.5ml/100g body weight twice a day (equivalent to 7.9g ethanol/kg/day). Each of 8 rats per group was selected using body weight at 10 days after acclimatization. Experimental animals were sacrificed after 60 days of continuous oral treatment of test substances with 20% ethanol treatment, and changes on the body weight, liver weight, and serum AST and ALT were observed. Results : There were dramatic decreases of body weight and increases of liver weight and serum AST and ALT. Similar inhibition effects on the EtOH-induced hepatic damages were detected between equal dosages of GJD and silymarin. Conclusion : Based on these results. it is concluded that GJD showed clear hepatoprotective effects on EtOH-induced hepatic damage.

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Mechanism of Ethanol-induced Purkinje Cell Death in Developing Rat Cerebellum: Its Implication in Apoptosis and Oxidative Damage

  • Song, Ji-Hoon;Kang, Ji-Hoon;Kang, Hee-Kyung;Kim, Kwang-Sik;Lee, Sung-Ho;Choi, Don-Chan;Cheon, Min-Seok;Park, Deok-Bae;Lee, Young-Ki
    • Development and Reproduction
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    • v.15 no.3
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    • pp.205-213
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    • 2011
  • Ethanol treatment during the brain growth spurt period has been known to induce the death of Purkinje cells. The underlying molecular mechanisms and the role of reactive oxygen species (ROS) in triggering ethanol-induced Purkinje cell death are, however, largely unresolved. We undertook TUNEL staining, western blotting assay and immunohistochemistry for the cleaved forms of caspase-3 and -9, with calbindin D28K double immunostaining to identify apoptotic Purkinje cells. The possibility of ROS-induced Purkinje cell death was immunohistochemically determined by using anti-8-hydroxy-2'deoxyguanosine (8-OHdG), a specific cellular marker for oxidative damage. The results show that Purkinje cell death of PD 5 rat cerebellum following ethanol administration is mediated by the activation of caspase-3 and -9. However, unexpectedly, TUNEL staining did not reveal any positive Purkinje cells while there were some TUNEL-positive cells in the internal and external granular layer. 8-OHdG was detected in the Purkinje cell layers at 8 h, peaked at 12-24 h, but not at 30 h post-ethanol treatment. No 8-0HdG immunoreactive cells were detected in the internal and external granular layer. The lobule specific 8-OHdG staining patterns following ethanol exposure are consistent with that of ethanol-induced Purkinje cell loss. Thus, we suggest that ethanol-induced Purkinje cell death may not occur by the classical apoptotic pathway and oxidative damage is involved in ethanol-induced Purkinje cell death in the developing cerebellum.

Comparison of Nondestructive Damage Sensitivity of Single Fiber/Epoxy Composites Using Ceramic PZT and Polymeric PVDF Sensors By Micromechanical Technique and Acoustic Emission (Micromechanical 시험법과 AE를 이용한 세라믹 PZT 및 고분자 PVDF 센서에 따른 단섬유 강화 에폭시 복합재료의 비파괴 손상감지능 비교)

  • Jung Jin-Kyu;Kim Dae-Sik;Park Joung-Man;Yoon Dong-Jin
    • Proceedings of the Korean Society For Composite Materials Conference
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    • 2004.04a
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    • pp.135-138
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    • 2004
  • Conventional piezoelectric lead-zirconate-titanate (PZT) senor has high sensitivity, but it is very brittle. Recently polymer films such as polyvinylidene fluoride (PVDF) and poly(vinylidene fluoride­trifluoroethylene) (P(VDF-TrFE)) copolymer have been used as a sensor. The advantages of polymer sensor are the flexibility and mechanical toughness. Simple process and possible several shapes are also additional advantages. Polymer sensor can be directly embedded in a structure. In this study, nondestructive damage sensitivity of single basalt fiber/epoxy composites was investigated with sensor type and thermal damage using AE and oscilloscope. And AE waveform for epoxy matrix with various damage types was compared to each other. The damage sensitivity of two polymer sensors was rather lower than that of PZT sensor. The damage sensitivity of PVDF sensor did not decrease until thermal damage temperature at $80^{\circ}C$ and they decreased significantly at $110^{\circ}C$ However, the damage sensitivity of P(VDF-TrFE) sensor at $110^{\circ}C$ was almost same in no damage sensor. For both top and side impacts, the difference in arrival time increased with increasing internal and surface damage density of epoxy matrix.

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