Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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A Case of Chronic Renal Failure Associated with Systemic Capillary Leak Syndrome

전신성 모세혈관 누출 증후군으로 인한 만성 신질환 1예

  • Baek, Seon Ha (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Shin, Nara (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Kim, Hyo Jin (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Han, Mi Yeun (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Choi, Dong-Ju (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Bang, Soo-Mee (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Kim, Sejoong (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Paik, Jin Ho (Department of Pathology, Seoul National University Bundang Hospital)
  • 백선하 (서울대학교 의과대학 내과학교실) ;
  • 신나라 (서울대학교 의과대학 내과학교실) ;
  • 김효진 (서울대학교 의과대학 내과학교실) ;
  • 한미연 (서울대학교 의과대학 내과학교실) ;
  • 최동주 (서울대학교 의과대학 내과학교실) ;
  • 방수미 (서울대학교 의과대학 내과학교실) ;
  • 김세중 (서울대학교 의과대학 내과학교실) ;
  • 백진호 (분당서울대학교병원 병리과)
  • Received : 2012.08.19
  • Accepted : 2012.10.02
  • Published : 2012.12.31
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Abstract

Systemic capillary leak syndrome (SCLS) is an unusual entity characterized by hypovolemic shock, hemoconcentration, and hypo-albuminemia associated with paraproteinemia as a result of marked capillary hyper-permeability. Complications of this syndrome can include compartment syndromes, pulmonary edema, thrombosis, and acute kidney injury. This paper reports a case of severe SCLS accompanied by acute tubular necrosis caused by hypoperfusion and myoglobinuria secondary to rhabdomyolysis, which resulted in chronic kidney disease that necessitated hemodialysis. However, there have been rare data of residual end-organ damage after acute attacks in Korea. Therefore, this paper reports a case of complicated SCLS enough to hemodialysis and that developed into chronic kidney disease.

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