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A Clinical Pilot Study of Carthami-Semen Herbal Acupuncture Treatment for Chronic Constipation (만성변비에 대한 홍화약침의 효능 연구)

  • Park, Jae-Woo;Yoon, Seong-Woo;Kim, Jin-Sung;Ryu, Bong-Ha
    • Journal of Acupuncture Research
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    • v.25 no.5
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    • pp.127-137
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    • 2008
  • Objectives : These days, herbal acupuncture therapy is widely applied to many diseases and symptoms by Korean medical doctors in Korea. The aim of this study was to demonstrate the effect of Carthami-Semen herbal acupuncture(CSHA) on chronic constipation. Methods : This single-blind placebo-controlled randomized parellel study enrolled 24 adults with chronic constipation. After one week's run-in period, they were randomly assigned to receive CSHA therapy, or placebo therapy for 4 weeks by 2 times per week. After completing 4 week's therapy, 2 week's follow-up period was continued. During study, defecation frequency, consistency and ease of evacuation were checked before study, every week and follow-up periods. Also, the VAS of constipation, quality of life(QoL) and heart rate variability(HRV : low frequency, high frequency) were checked 3 times totally. Finally, 21 subjects completed the protocol and 20 subjects were analyzed.(1 subject is excluded for analysis because of not following the protocol.) Results : In CSHA group, defecation frequency(continued after 1 week), consistency and ease of evacuation(at 1 week after and follow-up) were increased significantly. The VAS of constipation in CSHA group was significantly decreased. There was no significant change at QoL and HRV. Conclusions : CSHA therapy was effective in treating adults with chronic constipation. Study that have larger case number and longer follow up will be needed in the future.

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Influence of implant-abutment connection structure on peri-implant bone level in a second molar: A 1-year randomized controlled trial

  • Kim, Jin-Cheol;Lee, Jungwon;Kim, Sungtae;Koo, Ki-Tae;Kim, Hae-Young;Yeo, In-Sung Luke
    • The Journal of Advanced Prosthodontics
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    • v.11 no.3
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    • pp.147-154
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    • 2019
  • PURPOSE. This study aimed to evaluate the effect of two different implant-abutment connection structures with identical implant design on peri-implant bone level. MATERIALS AND METHODS. This clinical study was a patient-blind randomized controlled trial following the CONSORT 2010 checklists. This trial was conducted in 24 patients recruited between March 2013 and July 2015. Implants with internal friction connection were compared to those with external hex connection. One implant for each patient was installed, replacing the second molar. Implant-supported crowns were delivered at four months after implant insertion. Standardized periapical radiographs were taken at prosthesis delivery (baseline), and one year after delivery. On the radiographs, distance from implant shoulder to first bone-to-implant contact (DIB) and peri-implant area were measured, which were the primary and secondary outcome, respectively. RESULTS. Eleven external and eleven internal implants were analyzed. Mean changes of DIB from baseline to 1-year postloading were 0.59 (0.95) mm for the external and 0.01 (0.68) mm for the internal connection. Although no significant differences were found between the two groups, medium effect size was found in DIB between the connections (Cohen's d = 0.67). CONCLUSION. Considering the effect size in DIB, this study suggested the possibility of the internal friction connection structure for more effective preservation of marginal bone.

Optimum Control of a Photoelectric Dimming System in a Small Office with a Double Skin Envelope

  • Kim, Soo Young;Yum, Sung Kon
    • Architectural research
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    • v.7 no.2
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    • pp.47-54
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    • 2005
  • A photoelectric dimming control system for a small private office space with a double skin envelope system was analyzed for the purpose of examining optimum control performances under a variety of daylight conditions. Computer simulations were performed for the three different photosensor types positioned at the center of ceiling in the space. They were applied in both a south and north-facing room. Daylight conditions were a fixed horizontal venetian blind on an external envelope and a retractable shading device on an internal envelope under a clear, intermediate and overcast sky at different times of a day and year. Partially-shielded photosensors provided good control performances providing the required electric light output under clear and intermediate sky conditions. Unshielded photosensors failed to provide necessary illuminance levels producing less electric output and fully-shielded photosensors generally provided excessive light output. Reasonable electric lighting energy savings were achieved except under overcast sky conditions where the control system did not contribute to energy savings due to the less daylight through envelopes. The retractable shading device covering 50% of the internal envelope reduced energy savings up to 19.62%, but the workplane illuminance levels were maintained within recommended ranges. The coefficients of determination between workplane illuminance and photosensor illuminance due to daylight ranged from 0.74 to 0.98. Partially-shielded conditions provided best correlations and the north-facing room yielded stronger correlation than the south-facing room.

Intracoronary Radiation Therapy Using Re-188 after percutaneous Coronary Angioplasty (경피적 관동맥혈관성형술 후 Re-188을 이용한 혈관 내 방사선조사요법)

  • Chae, In-Ho;Lee, Myoung-Mook;Lee, Dong-Soo
    • 대한핵의학회:학술대회논문집
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    • 1999.05a
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    • pp.228-241
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    • 1999
  • Percutaneous coronary angioplasty is well established therapeutic modality in the management of coronary artery disease. However, the high restenosis rate of 30 to 50% limits its usefulness. The principal mechanism of restenosis, intimal hyperplasia, is the proliferative response of vessel wall to injury, which consists largely of smooth muscle cells. A large body of animal investigations and a limited number of clinical studies have established the ability of ionizing radiation to reduce neointimal proliferation and restenosis rate significantly. Human studies have been reported that intravascular radiation after first restenosis inhibits a second restenosis. Encouraged by these reports, we are also conducting a double blind, placebo-controlled, randomized trial to evaluate this new therapeutic modality in patients with coronary artery stenosis. The objective of our trial is to determine the safety and efficacy of catheter-based solutional beta emitting radioisotope system in preventing restenosis after angioplasty. This review describes the vascular brachytherapy systems and isotopes that have been utilized in the initial clinical trials performed in this area of post PTCA coronary restenosis. The results of many worldwide ongoing clinical trials will determine whether this new technology will change the future practice of vascular intervention.

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Current status and improvement strategies of emergency medical counseling service for overseas koreans (재외국민 응급의료상담 서비스의 이용 실태 및 서비스 향상방안)

  • Hyeon-Jeong Ko;Eun-Sook Choi
    • The Korean Journal of Emergency Medical Services
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    • v.28 no.1
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    • pp.77-95
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    • 2024
  • Purpose: This study aimed to analyze the counseling status of overseas Koreans using emergency medical counseling services, identify frequently occurring types of diseases, explore approaches to emergency treatment guidance, and protect overseas Koreans from medical blind spots, thereby enhancing the quality of emergency medical counseling services. Methods: This study was approved by the Institutional Review Board of Kongju National University (KNU_IRB_2023-31), and data were collected and analyzed from 10,951 cases of emergency medical counseling services utilized by overseas Koreans from the National Fire Agency from 2018 to 2022. Results: Emergency medical consultation services for overseas Koreans included a majority of non-trauma patients, with medical consultations being predominant. Terrestrial patients commonly seek advice for internal medical symptoms, whereas maritime patients frequently present with trauma-related symptoms, with a higher incidence of cardiac arrest and altered consciousness cases at sea. The development of self-diagnostic tests based on internal medicine symptoms is necessary for terrestrial patients, whereas stakeholder education is required for maritime patients. Conclusion: Due to the different types of diseases occurring in terrestrial and maritime patients, emergency medical consultation services for overseas Koreans should be implemented according to the specific characteristics of each patient. Therefore, it is necessary to develop and disseminate response manuals that are tailored to medical and trauma-related symptoms.

The clinical studies to developing BV Partner (BV Partner 개발을 위한 임상적 연구)

  • Kwon, Gi-Rok;Kang, Jae-Chun
    • Journal of Pharmacopuncture
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    • v.4 no.3
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    • pp.93-99
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    • 2001
  • Objective : This study was performed to examine the Herbal Acupuncture decrease the side effect of Bee Venom. Methods: We treated Bee Venom and various Herbal Acupuncture mixed Bee Venom using double blind test to 70th health youth, and checked pain, edema size, CBC, Serum biochemistry and Thermography. Results: 1. Herbal Acupuncture made by Morus bombycis Koidzumi showed good results to decrease the side effect of Bee Venom than any other Herbal Acupuncture. 2. We examined CBC, ESR and Serum biochemistry before and after treated. Special change was not showed. 3. We observed the pain and edema after treated Bee Venom and Morus bombycis Koidzumi Herbal Acupuncture mixed Bee Venom. We knew that Morus bombycis Koidzumi Herbal Acupuncture was decrease the pain and edema due to Bee Venom. 4. According to these clinical studies, Morns bombycis Koidzumi Herbal Acupuncture has a possibility to be a good partner of Bee Venom.

블라인드 장착에 따른 실내 공기 순환 연구

  • Nam, Do-U;Hwang, Jae-Min
    • Proceeding of EDISON Challenge
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    • 2016.03a
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    • pp.625-627
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    • 2016
  • 본 논문은 EDISON CFD의 전처리기, eMEGA를 이용하여 격자를 생성하고, 2차원 정렬 격자 기반 비압축성 해석자를 이용하여 유동해석을 진행한 뒤 후처리기, eDAVA를 통해 유동선을 그려 블라인드 장착에 따른 실내 공기 순환에 대한 연구 내용을 담고 있다. 본 연구는 시중에 판매중인 사생활 보호용 블라인드를 포함, 여러 블라인드의 장착 여부에 따라 실내 내부 공기 순환의 양상을 확인하고 실제로 블라인드 장착 시 실내환기에 어떤 영향을 주는지 유동 선을 통해 확인해 보았다. 블라인드 미장착시, 실내 전체적으로 공기가 고루 순환되는 모습을 보였으며, 블라인드 장착 시 대체로 블라인드 형태에 따라 유동이 이동하는 것을 볼 수 있었다. 본 연구는 사생활 보호와 환기 효율성의 관점에서의 소비자 선택권에 영향을 미치는 효과를 가져 올 것으로 보인다.

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Visual Analysis of Deep Q-network

  • Seng, Dewen;Zhang, Jiaming;Shi, Xiaoying
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.15 no.3
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    • pp.853-873
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    • 2021
  • In recent years, deep reinforcement learning (DRL) models are enjoying great interest as their success in a variety of challenging tasks. Deep Q-Network (DQN) is a widely used deep reinforcement learning model, which trains an intelligent agent that executes optimal actions while interacting with an environment. This model is well known for its ability to surpass skilled human players across many Atari 2600 games. Although DQN has achieved excellent performance in practice, there lacks a clear understanding of why the model works. In this paper, we present a visual analytics system for understanding deep Q-network in a non-blind matter. Based on the stored data generated from the training and testing process, four coordinated views are designed to expose the internal execution mechanism of DQN from different perspectives. We report the system performance and demonstrate its effectiveness through two case studies. By using our system, users can learn the relationship between states and Q-values, the function of convolutional layers, the strategies learned by DQN and the rationality of decisions made by the agent.

Effects of the Combination Herbal Extract on Working Memory and White Matter Integrity in Healthy Individuals with Subjective Memory Complaints : A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

  • Kwon, Oran;Lee, Sunho;Ban, Soonhyun;Im, Jooyeon J.;Lee, Doo Suk;Lee, Eun Hee;Kim, Joohee;Lim, Soo Mee;Lee, Sang Gon;Kang, Ilhyang;Kim, Kyung-Hee;Yoon, Sujung;Lee, Sun Hea
    • Korean Journal of Biological Psychiatry
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    • v.22 no.2
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    • pp.63-77
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    • 2015
  • Objectives The combination extract of four kinds of herbs, Gastrodia elata, Liriope platyphylla, Dimocarpus longan, and Salvia miltiorrhiza, has shown to have memory improving effects in mice. The aim of this study was to investigate the efficacy and safety of the herbal mixture for improving working memory as well as microstructural changes in white matter integrity in individuals with subjective memory complaints. Methods Seventy-five individuals with subjective memory complaints were assigned to receive either placebo (n = 15) or herbal mixture (low-dose group, n = 30 and high-dose group, n = 30) supplementation in an 8-week, randomized, double-blind, placebo-controlled clinical trial. Changes in working memory performance and fractional anisotropy (FA) values reflecting white matter integrity from baseline to 8-week endpoint were assessed. Results The herbal mixture group showed an increase in working memory performance compared to the placebo group (p for interaction = 0.001). In addition, the herbal mixture group showed an increase in FA values in the temporo-parietal regions (corrected p < 0.05), which are crucially involved in working memory function and are among the most affected regions in patients with cognitive impairments. Conclusions Findings from this study indicate that the herbal mixture may be a promising therapeutic option for individuals with subjective memory complaints.

The effects of Sa-am Acupuncture Simpojeongkyeok Treatment on Hwa-byung : Randomized, patient-assessor blind, placebo-controlled acupuncture, pilot clinical trial (화병에 대한 사암침 심포정격의 치료 효과 : 환자-평가자 눈가림, 무작위배정 대조군 임상시험)

  • Choi, Woo-Jin;Lee, Seung-Gi;Son, In-Bong;Sun, Seung-Ho
    • Journal of Oriental Neuropsychiatry
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    • v.22 no.2
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    • pp.1-13
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    • 2011
  • Objectives : The purpose of this research is to examine the effects of Sa-am acupuncture Simpojeongkyeok treatment on Hwa-byung. Methods : The study was performed through a patient-assessor blind, randomized, placebo-controlled trial in which the volunteers, data collector and analyst were unaware of individuals which were receiving the treatment. Fifty volunteers were divided into a trial and a control group, each of which consisted of 25 subjects. The trial group was treated with Sa-am acupuncture Simpojeongkyeok, while needle insertion at non-acupoints was given to the control group. The Likert scale for major symptoms of Hwa-byung was measured as the 1st evaluative instrument, and then a comparative analysis was conducted by comparing the results with those measured by of STAXI-K, STAI-K and BDI-K. Results : In the Likert scale comparison of major symptoms, total scores in both groups were decreased after treatment. However, a more significant decrease was found in those of trial group compared to those of the control group from a statistical perspective. The results measured by BDI scores also decreased significantly in the trial group after treatment. In comparison of STAXI and STAI scores, there were no significant differences found between the groups. Conclusions : The results suggest that Sa-am Acupuncture Simpojeongkyeok treatment is effective in the treatment of Hwa-byung.