• The Korean Journal of Physiology and Pharmacology
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• 제21권6호
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• pp.633-641
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• 2017

The aim of this study is to investigate the effects of intermittent ladder-climbing exercise training on mitochondrial biogenesis and ER stress of the cardiac muscle in high fat diet-induced obese middle-aged rats. We induced obesity over 6 weeks of period in 40 male Sprague-Dawley rats around 50 weeks old, and were randomly divided into four experimental groups: chow, HFD, exercise+HFD, and exercise+chow. The exercising groups underwent high-intensity intermittent training using a ladder-climbing and weight exercise 3 days/week for a total of 8 weeks. High-fat diet and concurrent exercise resulted in no significant reduction in body weight but caused a significant reduction in visceral fat weight (p<0.05). Expression of $PPAR{\delta}$ increased in the exercise groups and was significantly increased in the high-fat diet+exercise group (p<0.05). Among the ER stress-related proteins, the expression levels of p-PERK and CHOP, related to cardiac muscle damage, were significantly higher in the cardiac muscle of the high-fat diet group (p<0.05), and were significantly reduced by intermittent ladder-climbing exercise training (p<0.05). Specifically, this reduction was greater when the rats underwent exercise after switching back to the chow diet with a reduced caloric intake. Collectively, these results suggest that the combination of intermittent ladder-climbing exercise training and a reduced caloric intake can decrease the levels of ER stress-related proteins that contribute to cardiac muscle damage in obesity and aging. However, additional validation is required to understand the effects of these changes on mitochondrial biogenesis during exercise.

• 대한간호학회지
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• 제25권2호
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• pp.193-209
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• 1995

The purpose of this study was to determine the effect of intermittent low - intensity, short duration exercise during hindlimb suspension on the mass, relative weight, myofibrillar protein content, cross-sectional area of Type I and Type II fibers and SDH activity in Type II(plantaris) muscle. To examine the effectiveness of intermittent low-intensity, short duration exercise on mass, myofibrillar protein content and fiber size, the hindlimbs of adult female Wistar rats were suspended(HS) and half of these rats walked on a treadmill for 45 min/day(9 min every 2h) at 5m /min and a 15$^{\circ}$grade (HS-EX). Plantaris wet weight was 19.67% significantly smaller(p<0.005) and relative plantaris weight was 6.25% smaller compared with those of control rats following seven days of hindlimb suspension. Plantaris wet weight and relative plantaris weight increased by 27.66%, 12.22% each through intermit-tent exercise during hindlimb suspension(p<0.005, p<0.05), moreover, plantaris wet weight and relative plantaris weight of the HS-EX rats were similar to those of control rats. Soleus wet weight and relative soleus weight decreased significantly by 31% and 22.0% in the HS rats(p<0.05). Soleus wet weight and relative soleus weight increased by 10.41%, 25.64% respectively through intermittent ex-ercise during hindlimb suspension, furthermore, soleus wet weight and relative weight of the HS-EX rats were closer to those of control rats. Myofibrillar protein content of plantaris and soleus decreased significantly by 51.49%, 59.65% each, following seven days of hindlimb suspension (p<0.005) Myofibrillar protein content of plantaris and soleus increased by 51.79%, 75.47% each with significance through intermittent exercise during hindlimb suspension(p<0.005). Myofibrillar protein content of plantaris and soleus in HS-EX rats was smaller than that of control rats. No change was observed in fiber type percentage following 1 week of hindlimb suspension or exercise during hindlimb suspension. The type I fiber cross-sectional area of both soleus and plantaris muscle was 18.72% and 41.07% lower in the HS than that of the controls (p<0.05, p<.001), that of both muscles was 6.60% and 29. 3％ greater in the HS-EX than that of the HS rats. HS plus intermittent low- intensity short duration exercise resulted in Type I fiber cross-sectional area closer to the controls. Type II fiber cross-sectional area of both plantaris and soleus muscle was 22.45% and 22.58% sl nailer in the HS than in the controls, that of both muschles in the HS-EX was 14.10%, 5.78% greater than HS. Intermittent exercise during hindlimb suspension resulted in Type I, II fiber cross-sectional area closer to the control value. There was no change in SDH activity following 1week of hindlimb suspension or exercise during hindlimb suspension in the plantaris muscle. The results suggest that intermittent low intensity short duration exercise can ameliorate Type II muscular atrophy Induced by hindlimb suspension.

• 신경치료
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• 제22권3호
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• pp.25-29
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• 2018

Purpose In this study, 45 students were divided into task - oriented group, task - oriented intermittent group, and continuous group, and the effect of each variable on learning was changed to angle of the arms' we checked. Methods This study was conducted for 45 days from March 13 to 18, 2017 for five days in the 20 generals living in Changwon city. Dart and goniometer were used for the measurement. In the exercise program, darts were placed on a smooth, hard surface of 1.5M height and the distance to the subject was set 1.5m away. In the dart throw practice, all three groups were marked with an elbow flexion $30^{\circ}$ on the wall, and the subjects were instructed to throw the dart at that point. Results Comparisons between groups showed significant differences between the continuous task-oriented training group and the intermittent task-oriented training group and the control group at the end of training (*** P <0.001). Conclusion This study showed that the intermittent task-oriented training method showed the highest effect (*** P <0.001), which proved that the intermittent method is the most effective exercise method among the three groups.

• 디지털융복합연구
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• 제13권5호
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• pp.393-400
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• 2015

본 연구는 중년여성을 대상으로 12주간의 간헐적 단식과 저항운동이 성호르몬과 당대사 변인에 어떤 영향을 주는지 알아보고자 하였다. 이에 두 그룹을 선정하여 EG에는 간헐적 단식과 저항운동을 적용하였으며, CG는 통제군으로서 EG의 효과를 검증할 수 있는 군으로 설정하였다. EG에 적용된 간헐적 단식은 주당 1회 24시간의 단식을 실시하였으며, 저항운동은 주 당 3회 60분간 1RM을 기준으로 60% 강도로 실시하였다. 각 측정변인은 12주간의 처치전후 측정하여 처치효과를 검증하였다. 이와 같은 절차를 통해 다음과 같은 결론을 얻었다. 첫째, 간헐적 단식과 저항운동을 적용한 그룹에서 성호르몬(에스트라디올, 테스토스테론)의 변화에 유의한 상호작용효과를 나타냈다. 둘째, 간헐적 단식과 저항운동을 적용한 그룹에서 당대사변인(글루코스, 인슐린, HOMA-IR)의 변화에 유의한 상호작용효과를 나타냈다. 본 연구는 간헐적 단식과 저항운동을 동시에 적용하여 진행하여 긍정적인 결과를 얻었다. 하지만 간헐적 단식과 저항운동 각각의 효과를 검증하는 데는 한계가 있는 것으로 판단된다.

• 운동영양학회지
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• 제25권2호
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• pp.15-19
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• 2021

[Purpose] Skeletal muscle glycogen is a determinant of endurance capacity for some athletes. Ginger is well known to possess nutritional effects, such as anti-diabetic effects. We hypothesized that ginger extract (GE) ingestion increases skeletal muscle glycogen by enhancing fat oxidation. Thus, we investigated the effect of GE ingestion on exercise capacity, skeletal muscle glycogen, and certain blood metabolites in exercised rats. [Methods] First, we evaluated the influence of GE ingestion on body weight and elevation of exercise performance in rats fed with different volumes of GE. Next, we measured the skeletal muscle glycogen content and free fatty acid (FFA) levels in GE-fed rats. Finally, we demonstrated that GE ingestion contributes to endurance capacity during intermittent exercise to exhaustion. [Results] We confirmed that GE ingestion increased exercise performance (p<0.05) and elevated the skeletal muscle glycogen content compared to the nonGE-fed (CE, control exercise) group before exercise (Soleus: p<0.01, Plantaris: p<0.01, Gastrocnemius: p<0.05). Blood FFA levels in the GE group were significantly higher than those in the CE group after exercise (p<0.05). Moreover, we demonstrated that exercise capacity was maintained in the CE group during intermittent exercise (p<0.05). [Conclusion] These findings indicate that GE ingestion increases skeletal muscle glycogen content and exercise performance through the upregulation of fat oxidation.

• 대한물리의학회지
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• 제14권4호
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• pp.19-27
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• 2019

PURPOSE: This study examined which stretching exercise had the most positive effect on increasing the range of motion (ROM) of the knee joint in healthy people and whether there was a difference between continuous stretching and intermittent stretching. METHODS: This study included 30 healthy university students from OOO University. The subjects were asked to sit on a mat and perform hamstring-stretching exercise during which the ROM and muscle tone were measured with pre and post-tests. Each subject was assigned randomly to a continuous stretching group (stretching without relaxation time group, n=10, G1) or intermittent stretching group (stretching with 10s relaxing time group, n=10, G2; and stretching with 20s relaxing time group, n=10, G3). The participants conducted hamstring stretching exercises with a sit-and-reach box at three different rest times (0s, 10s, and 20s). Subsequently, they underwent passive knee extension (PKE) tests, in which the ROM of the knee joint was measured with a goniometer, and the muscle tone was evaluated using a MyotonPro. RESULTS: Significant differences in muscle tone, stiffness, and ROM were observed between pre-test and post-test in each groups (p<.05). Although the post hoc tests indicated no significant differences in muscle tone and ROM between the continuous stretching group and intermittent stretching group (p>.05), the rate of change of the ROM showed that the intermittent stretching group developed more effective maintenance of the hamstring flexibility. CONCLUSION: No significant differences in the muscle tone of the hamstring and ROM of the knee joint were observed according to the hamstring stretching exercises with three different rest times. On the other hand, the rate of change of the ROM showed that intermittent stretching maintained the hamstring flexibility more effectively.

• 운동영양학회지
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• 제25권3호
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• pp.8-15
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• 2021

[Purpose] Excessive reactive oxygen species (ROS) induced by prolonged high-intensity exercise can cause structural and functional damage. Antioxidant polyphenol supplementation, which reduces ROS levels, may improve high-intensity exercise performance. We evaluated the effect of lychee fruit extract, which contains high levels of low-molecular-weight oligomerized polyphenols, on high-intensity exercise performance. [Methods] Ten male athletes were included in an open-label trial that consisted of control and intervention phases, with a 7-day washout period between phases. The participants were administered oligomerized lychee fruit extract for seven days, whereas no intervention was given in the control phase. High-intensity intermittent exercise and the Wingate test were performed. The power output, blood lactate levels, reactive oxygen metabolite levels, biological antioxidant potential, heart rate, and rate of perceived exertion were measured. [Results] The average power output was significantly higher in the intervention phase than in the control phase (P < 0.01), while the change in blood lactate levels was significantly lower in the intervention phase than in the control phase (P < 0.05). The average heart rate was significantly higher in the intervention phase than in the control phase (P < 0.05), without changing the rate of perceived exertion. Although there was no difference in reactive oxygen metabolite levels between the phase, the change in biological antioxidant potential was larger in the intervention phase than in the control phase (P = 0.06). The Wingate test showed no significant differences between the phase. [Conclusion] Short-term loading with oligomerized lychee fruit extract may increase performance during high-intensity intermittent exercise by improving metabolism.

• 전기의세계
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• 제27권4호
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• pp.41-44
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• 1978

Intermittent failures exercise their effects only part of the time but constitute a dominant factor for the field failures. We consider the data raliability of the partially self-checking network with which a single intermittent failure will be recovered by a rollback method. Even if the self-testingness of partially self-checking network is guranteed for a set of permanent failures, it sometimes may not be so for intermittent failures. We introduce the notion of error residual and provide the basis for calculating the data reliability. Both the duration of each intermittent failure and the occurrence interval of successive ones are assumed to be negative exponentially distributed; the convolution of the intervals is distributed according to an Erlangen distribution.

• 한국융합학회논문지
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• 제10권4호
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• pp.195-201
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• 2019

유산소성 운동수행능력의 필드테스트로 대표되는 셔틀런 테스트와 요요테스트를 최대산소섭취량 및 다른 주행테스트들과 비교 검토함으로써 대학 축구선수들의 심폐지구력을 평가하는 유효한 필드테스트를 제안하는 것을 목적으로 하였다. 셔틀런 테스트는 휴식구간이 없이 지속적으로 달려야 하는 반면 요요 테스트의 경우 휴식구간이 설정되어 있어 휴식기를 활용하여 컨디션을 조절하며 주행한다는 특성이 있다. 따라서 요요테스트는 주행과 회복을 반복하는 간헐적 운동을 주로 하는 축구선수들의 종목 특성을 고려한 심폐기능 평가 시 보다 효율적인 현장검사로 활용될 수 있을 것이다.

• 한국산학기술학회논문지
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• 제11권11호
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• pp.4234-4243
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• 2010

치매의 특성상 집중력 결핍, 불안, 긴장 등으로 운동지도 현장에서 치매 고령자에게 운동을 지도하는데 어려움이 따른다. 이에 운동시간을 배분하여 실시하는 방법인 간헐적 운동을 제시하고자 한다. 연속적 운동과 간헐적 운동이 기능적 체력, 인지기능 및 일상생활수행능력에 미치는 영향을 구명하여 이들을 위한 적절한 운동 처방의 자료로 활용하는데 있다. 대상자 선정은 B광역시 A치매전문요양원에 거주하고 있는 여성 고령자로 DSM-IV 기준에 따라 확정적 치매의 진단을 받은 자이다. 연속적 운동군 6명, 간헐적 운동군 5명으로 총 11명을 최종 대상자로 선정하였다. 손발운동, 한국무용과 밴드운동을 실시하였다. 주 3회, 총 12주간 실시하였다. Borg's scale을 이용하여 준비 및 정리운동은 RPE 7-9, 본 운동은 RPE 11-13의 수준으로 실시하였다. 연속적 운동군은 1일 1회 30분간, 간헐적 운동군은 1일 3회 10분씩 총 30분간 실시하였다. 모든 자료는 SPSS Ver. 18.0을 사용하여 평균값과 표준편차를 산출하고, two-way repeated ANOVA를 실시하였다. 통계적 유의수준은 .05로 설정하였다. 기능적 체력과 인지기능에서 시기간 유의한 차이가 있었다. 일상생활수행능력에서 시기에서 차이가 없었다. 모든 항목에서 집단, 시기${\times}$집단은 유의한 차이가 없었다. 연속적 운동군과 간헐적 운동군의 효과가 유사하게 나타났다. 이는 모든 치매환자에게 일반화시키기에는 제한이 있지만 운동시간 배분에 있어 연속적 운동방법과 유사하게 간헐적 운동의 방법도 경증치매환자의 운동처방에 유효한 자료가 될 것으로 본다.