• Communications for Statistical Applications and Methods
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• v.15 no.5
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• pp.727-735
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• 2008

Consider a clinical trial in which the main end-point is survival. Suppose after the start of the study an intermediate event occurs which may be influenced by a covariate(or treatment). In many clinical studies the occurrence of an intermediate event may change the survival distribution. This investigation develops two-stage model which, in the first stage, models the effect of covariate on the intermediate event and models the relationship between survival time and covariate as well as the intermediate event. In this paper, the two-stage model is presented in order to model intermediate event and a test based on this model is also provided. A numerical simulations are carried out to evaluate its overall significance level.

• Journal of Information Display
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• v.11 no.1
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• pp.1-7
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• 2010

The intermediate connectors play crucial roles in the performance of tandem organic light-emitting diodes (OLEDs) because they are required to facilitate charge carrier transport and to guarantee transparency for light transmission and deposition compatibility. Understanding the physical properties of the intermediate connector is not only fundamentally important but is also crucial to developing high-efficiency organic devices with a tandem structure. In this study, several effective intermediate connectors in tandem OLEDs using a doped or non-doped organic p-n heterojunction were systematically investigated by studying their interfacial electronic structures and corresponding device characteristics. The working mechanisms of the intermediate connectors are discussed herein by referring to their relevant energy levels with respect to those of the neighboring organic layers. The factors affecting the operation of the intermediate connectors in tandem OLEDs, as demonstrated herein, provide guidance for the identification of new materials and device architectures for high-performance devices.

• Applied Microscopy
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• v.21 no.1
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• pp.46-62
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• 1991

The intermediate filament is one of the most important constituents of the intracytoplasmic cytoskeleton microtubule, actin, myosin and intermediate filament. It is composed of keratin, desmin, vimentin, neurofilament and glial filament, and has important role as a cellular marker, epithelial or mesenchymal origin. So it will be important to differentiated from some poorly or undifferentiated neoplasm to provide adequate therapeutic modalities. This study was performed by using immunohistochemical staining and electron microscopic observation to find out intermediate filaments of epithelial and non-epithelial tumor cells evaluate the degree of differentiation in tumors and therefore to provide some diagnostic and therapeutic modalities. The materials consisted of 83 epithelial and non-epithelial elements bearing 23 normal control, 28 epithelial tumors, and 32 non-epithelial tumors, that are resected for definite treatment at Chosun University Hospital from June, 1988 to June, 1990. Immunohistochemical stain for keratin, desmin and vimentin, and electron microscopic study were performed in all cases. The results obtained were as follows. 1. Immunohistochemical stain for intermediate filament were very useful diagnostic aid for differentiated epithelial tumor to non-epithelial tumor in diagnostic neoplasia. 2. In the electron microscopic finding, the size of intermediate filaments were possible differentiated to cell components of epithelial tumor and non-epithelial tumors.

• Corrosion Science and Technology
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• v.19 no.2
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• pp.51-56
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• 2020

The objective of this study was to improve properties of plasma sprayed HAp layer to titanium substrate by introducing an intermediate layer with two different methods. Before applying Zn doped HAp coating on titanium substrate, an intermediate layer was introduced by titanium plasma spray or titanium anodization. Heat treatments were conducted for some samples after titanium intermediate layer was formed. Zn doped HAp top layer was applied by plasma spraying. Three-point bending test and pull-off adhesion test were performed to determine the adhesion of Zn doped HAp coatings to substrates. Long-term credibility of Zn doped HAp plasma sprayed coatings on titanium was assessed by electrochemical impedance measurements in Hanks' solution. It was found that both titanium plasma sprayed and titanium anodized intermediate layer had excellent credibility. Strong adhesion to the titanium substrate was confirmed after 12 weeks of immersion for coating samples with titanium plasma sprayed intermediate layer. Samples with titanium anodized intermediate layer showed good bending strength. However, they showed relatively poor resistance against pulling off. The thickness of titanium anodized intermediate layer can be controlled much more precisely than that of plasma sprayed one, which is important for practical application.

• Advances in nano research
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• v.12 no.4
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• pp.365-374
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• 2022

Intermediate filaments are the mechanical ropes for both cytoskeleton and nucleoskeleton of the cell which provide tensile force to these skeletons. In providing the mechanical support to the cell, they are likely to buckle. We used conventional Euler buckling model to find the critical buckling force under different boundary conditions which they assume during different functions. However, there are many experimental and theoretical studies about other cytoskeleton components which demonstrate that due to mechanical coupling with the surrounding surface, the critical buckling force increases considerably. Motivated with these results, we also investigated the influence of surface effects on the critical buckling force of intermediate filaments. The surface effects become profound because of increasing ratio of surface area of intermediate filaments to bulk at nano-scale. The model has been solved analytically to obtain relations for the critical forces for the buckling of intermediate filaments without and with surface effects. We found that critical buckling force with surface effects increases to a large extent due to mechanical coupling of intermediate filaments with the surrounding surface. Our study may be useful to develop a unified experimental protocol to characterize the physical properties of Intermediate filaments and may be helpful in understanding many biological phenomenon involving intermediate filaments.

• Korea Trade Review
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• v.41 no.1
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• pp.159-186
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• 2016

This study analyzes the degree of dependency and comparative advantage of each country for intermediate goods trade in East Asia, which predicts the comparative advantage of the intermediate goods trade and fragmentation in East Asia when the FTA arrangement in East Asia is implemented. The results are as follows. First, the share of intra-regional trade in the intermediate goods in East Asia has increased over time, implying the deepening of interdependency in intermediate goods trade within the East Asia. Second, Korea is a net exporter in intermediate goods trade for China and ASEAN, whereas it is a net importer for Japan. Japan is a high net exporter for all East Asia, while China is a net importer for Korea, Japan and ASEAN. If FTA arrangement in East Asia is implemented, Japan and Korea will be key suppliers of the intermediate goods for East Asia, while China and ASEAN will play a role of the manufacturing factory through the import of intermediate goods. Third, Korea has a comparative advantage in intermediate trade of electric and electronics and transport vehicle industry in East Asia. Japan has a comparative advantage in all of electric and electronics, transport vehicle, precision instrument, general machinery industry, whereas China has a comparative advantage only in electric and electronics intermediate trade in East Asia. The intra-industry trade of the intermediate goods in precision instrument, general machinery industry is expected to grow among Korea, Japan and China.

• International Journal of Naval Architecture and Ocean Engineering
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• v.12 no.1
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• pp.157-167
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• 2020

The purpose of this study is to analyze the relationship between the occurrence of intermediate peak and time duration, and to conduct a review for the causes of the intermediate peak. In this test, ice impact tests were conducted using a bow side shell frame and ice specimen. A total of 70 samples were manufactured. Two types of ice specimen with relatively different surface conditions were used. The criterion for dividing the two types of ice specimen was the different exposure times to room temperature after freezing. This experiment was conducted for each parameter in order to reproduce the actual icebreaking situation. As a result of the analysis, the intermediate peak in the ice load signal have been found to be caused by mechanisms by which the inner surface of broken ice contact with hull immediately after the initial hitting point of ice has been broken.

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.225-228
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• 2009

We have demonstrated several effective intermediate connectors in tandem organic light-emitting devices (OLEDs) using doped or nondoped organic p-n heterojunction. The influence of n-type or p-type organic layer in intermediate connectors on device performance has been investigated based on the understanding of interfacial electronic structures.

• Journal of the Korean Society for Precision Engineering
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• v.16 no.7
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• pp.132-143
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• 1999

In this study, an intermediate model is presented as a new method for development of a parametric simulation program. This model enables us to analyze effectively the static and dynamic structure of a real production system. The static structure of the real system can be modelled in an entity-relationship diagram and the dynamic structure of the real system in a Petri net. The intermediate model consists of an entity-relationship diagram and a Petri net. Using this intermediate model man can not only reduce the time and cost for simulation program development, but also increase the modelling reliability of the developed simulation program. To show the usefulness of this intermediate model. the intermediate models for two production subsystems, manufacturing sub-system and transport subsystem, are set up.

• Korea Trade Review
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• v.46 no.5
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• pp.83-98
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• 2021

This study aims to examine the effects of international trade in intermediate input on the implications of international business cycle properties in Korea. To do this, I have extended standard one goods New Keynesian international business cycle model to incorporate the role of intermediate inputs. After constructing the DSGE model, I have analysed the impulse response function and varian decomposition results. The results show that the model could introduce a new channel, that is, "cost channel" like Eyquem and Kamber (2014). In other words, the model has changed the dynamics of aggregate inflation by the cost channel. When the trade in intermediate goods increase, which is measured by openness of foreign input, the volatility of output, consumption and inflation increase two or three times. However, the model itself fails to explain the full account of cycle behavior of historical data, but the results imply that the trade in intermediate input assumption can help to improve the forecasting ability of international business cycle models.