• Communications for Statistical Applications and Methods
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• 제15권4호
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• pp.497-507
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• 2008

동일 환경에서 할 수 있는 실험의 크기가 2인 경우 $2^n$요인실험과 그 일부실시법을 설계하려면 교락법을 반복적으로 사용해야한다. $2^n$요인실험 또는 그 일부실시법의 교락법들을 적절히 조합하면 모든 주효과와 2인자 교호작용효과 전부 또는 일부를 검출할 수 있는 실험을 설계할 수 있다. 이런 실험을 설계하기 위해 정의대비를 이용했고 설계된 실험의 처리조합을 제시하였다.

• 한국항공우주학회지
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• 제34권1호
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• pp.49-55
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• 2006

본 연구에서는 공력설계공간의 지식습득을 위해 분산해석법과 자기조직화지도의 이용을 제안하였다. 이 기법들은 각각의 설계변수가 목적함수에 미치는 영향을 예측 가능하게 한다. 더욱이, 분산해석법은 설계변수들의 상호관계가 목적함수에 미치는 영향도 예측 가능하게 하며, 자기조직화지도는 목적함수들 사이에 어떠한 trade-off관계가 있는지도 예측 가능하게 한다. 본 논문에서 72개의 설계변수와 4개의 목적함수를 가진 초음속 날개 설계의 결과에 대하여 이들의 데이터 마이닝 기법들을 적용하였다.

• Journal of Dairy Science and Biotechnology
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• 제18권1호
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• pp.47-60
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• 2000

Over decades of work, the probiotic research has grown rapidly with a number of new cultures, which is claimed a variety of benefit. However, many of the specific effects attributed to the ingestion of probiotics remain convoluted and scientifically unsubstantiated. Accordingly, the scientific community faces a greater challenge and must objectively seek cause and effect relationships for many potential and currently investigated probiotic species. Rational selection and design of probiotics remains an important challenge and will require a solid information about the physiology and genetics of candidate strains relevant to their intestinal roles, functional activities, and interaction of with other resident micro flora. As far as beneficial culture of lactic acid bacteria (LAB) is concerned, simple, cost-effective, and exact identification of candidate strains is of foremost importance among others. Until recently, the relatedness of bacterial isolates has been determined sorely by testing for one or several phenotyphic markers, using methods such as serotyping, phage-typing, biotyping, and so forth. However, there are problems in the use of many of these phenotype-based methods. In contrast, some of newer molecular typing methods involving the analysis of DNA offer many advantages over traditional techniques. These DNA-based methods have the greater discriminatory power than that of phenotypic procedures. This review focuses on the importance and the basis of molecular typing methods along with some considerations on de-sign and selection of probiotic culture for human consumption.

• 한국자동차공학회논문집
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• 제4권1호
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• pp.165-176
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• 1996

The flow field and spray characteristics for loop scavenged type 2stroke engine having pancake shape was numerically computed using KIVA-Ⅱ code. The cylinder has 1intake port, 2side intake ports and 1exhaust port with induced flow angle 25 deg. In engine calculation, the chop techniques is used to strip or add planes of cells across the mesh adjacent to the TDC and the BDC(ports parts) for preventing the demand of exceed time during the computation, providing a control on cell height in the squish region. The modified turbulent model including the consideration of the compressibility effect due to the compression and expansion of piston was also used. The case of 25 deg.(injection angle) which is opposite to scavenging flow direction shows better the distribution of droplets and the evaporation rate of droplets compared to other cases(0 deg., - 25 deg.). When injection pressure was increased, the spray tip penetration became longer. When injection pressure was increased, the interaction between the upward gas velocity and spray droplets strongly cause. Thus the breakup of droplets is strongly occurred and the evaporation rate of droplets was found to be better.

• 한국컴퓨터정보학회논문지
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• 제13권6호
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• pp.263-271
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• 2008

본 논문에서는 한국어 정보처리 기술을 사용한 모바일 환경의 대화형 에이전트 시스템에 대해 논한다. 대화형 에이전트 시스템 구축의 목적은 인간 사용자와 시스템 에이전트간의 자연어 인터페이스를 제공하여 보다 편리한 상호작용을 가능하게 하는 데 있다. 모바일 환경의 대화형 에이전트를 구축하기 위해서는 구어체 발화에 특화된 다양한 언어 처리 및 언어 이해 요소들이 필요하다. 본 시스템은 입력 문장의 오류처리, 형태소 분석 및 품사 태깅, 양태 분석, 논항 인식 및 의미프레임 생성, 그리고 유사 발화 검색 및 응답 생성으로 구성된다. 주어진 사용자 발화에 적절한 응답을 생성하기 위해서 본 시스템은 사용자 발화와 예제 발화 간의 어휘적, 통사/구문적, 의미적 유사도 정보를 활용하여 예제기반 응답 검색을 수행한다.

• Elastomers and Composites
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• 제53권2호
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• pp.57-66
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• 2018

Styrene-butadiene rubber (SBR), reinforced with different contents of silica (with or without modification using silane coupling agents), was prepared by a modified sol-gel method involving hydrolyzation of tetraethoxysilane over an acid catalyst. The structures of the as-prepared samples were characterized using various techniques, such as scanning electron microscopy, X-ray photoelectron spectroscopy, Fourier-transform infrared spectroscopy, and thermogravimetric analysis. The mechanical properties of the as-prepared samples were discussed in detail. The results revealed an increasing of the storage modulus (G') with increase in the silica content without modification. In contrast, G' decreased after modification using silane coupling agents, indicating a reduction in the silica-silica interaction and improved dispersion of silica in the SBR matrix. Both tensile stress and hardness increased with increase in the silica content (with modification) in the SBR matrix, albeit with low values compared to the samples with un-modified silica, except for the case of silica modified using (3-glycidyloxypropyl) trimethoxysilane (GPTS). The latter observation can be attributed to the special structure of GPTS and the effort of oxygen atom lone-pair.

• Journal of Microbiology and Biotechnology
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• 제16권9호
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• pp.1429-1433
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• 2006

Application of recombinant protein production and particularly their isotopic enrichment has stimulated development of a range of novel multidimensional heteronuclear NMR techniques. Peptides in most cases are amenable to assignment and structure determination without the need for isotopic labeling. However, there are many cases where the availability of $^{15}N$ and/or $^{13}C$ labeled peptides is useful to study the structure of peptides with more than 30 residues and the interaction between peptides and membrane. CRAMP (Cathelicidin-Related AntiMicrobial Peptide) was identified from a cDNA clone derived from mouse femoral marrow cells as a member of cathelicidin-derived antimicrobial peptides. CRAMP was successfully expressed as a GST-fused form in E. coli and purified using affinity chromatography and reverse-phase chromatography. The yield of the CRAMP was 1.5 mg/l 1. According to CD spectra, CRAMP adopted ${\alpha}$-helical conformation in membrane-mimetic environments. Isotope labeling of CRAMP is expected to make it possible to study the structure and dynamic properties of CRAMP in various membrane systems.

• 한국표면공학회지
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• 제43권1호
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• pp.1-6
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• 2010

The effect of organic additives, 1-(3-sulfoproyl)-2-vinylpyridineium hydroxide (SVH) and thiourea (TU), on the precision copper electrodeposition was investigated with optical, electrochemical and x-ray diffraction techniques. It was found that SVH played a r ole as a n accelerator and TU as an i nhibitor during the electroreduction of cupric ions in acidic Cu electroplating solution. Through electrochemical measurements, TU showed more strong interaction with cupric ions than SVH and dominated overall Cu electroplating process when both additives were present in the solution. In the case of three dimensional Cu electrodeposition on the 20 ${\mu}m$-patterned Ni substrates, SVH controlled the upright growth of Cu electrodeposits and so determined its flatness, while TU prohibited the lateral spreading of Cu in the course of pulse-reverse pulse current adaptation. With microscopic observation, we obtained the optimum organic additives composition, that is, 100 ppm SVH and 200 ppm TU during the current pulsation.

• 한국CDE학회논문집
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• 제14권6호
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• pp.415-423
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• 2009

Because of the fast changing car design and increasing facilities, manufacturing process of cars is getting more complex now a days. Particularly, car manufacturing system that consist of automated devices, applies various simulation techniques to validate device motion and detect collision. To cope with this problem, traditional manufacturing system deployed test-run with the real devices. However, increased computing power in a contemporary manufacturing system changes it into realistic 3D simulation environment. Similarly, managed device data that was generated using 2D traditionally, can be converted to 3D realistic simulation. The existing problem with 3D simulation is disjoint data interaction between different work stations. Consequently, JIGs, fixing the car part accurately, are changed according to fixing position on the part or a part shape properties. In practice, the 3D JIG data has to be managed according to kinematic information, but not of its features. However, generating kinematic information to the 3D model repeatedly according to frequent change in part is not explained in current literatures. To fill this knowledge gap, this paper suggests an improving method of rendering 3D JIG kinematics information to simulation model. Thereafter, it shows the result of implementation.

• Bulletin of the Korean Chemical Society
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• 제32권3호
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• pp.947-955
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• 2011

The complexes [Pd(bpy)(Hex-dtc)]$NO_3$ and [Pt(bpy)(Hex-dtc)]$NO_3$ (bpy is 2,2'-bipyridine and Hex-dtc is hexyldithiocarbamato ligands) were synthesized and characterized by elemental analysis and spectroscopic studies. The cytotoxicity assay of the complexes has been performed on chronic myelogenous leukemia cell line, K562, at micromolar concentration. Both complexes showed cytotoxic activity far better than that of cisplatin under the same experimental conditions. The binding parameters of the complexes with calf thymus DNA (CT-DNA) was investigated using UV-visible and fluorescence techniques. They show the ability of cooperatively intercalating in CT-DNA. Gel filtration studies demonstrated that platinum complex could cleave the DNA. In the interaction studies between the Pd(II) and Pt(II) complexes with CT-DNA, several binding and thermodynamic parameters have been determined, which may provide deeper insights into the mechanism of action of these types of complexes with nucleic acids.