• Title/Summary/Keyword: Interaction mode

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The Effects of Various Extracellular Matrices on Motility of Cultured MC3T3-E1 Cell (다양한 세포외기질이 배양 골아세포의 이동에 미치는 영향)

  • Park, Beyoung Yun;Seo, Sang Woo;Lee, Won Jai;Ryu, Chang Woo;Rah, Dong Kyun;Son, Hyun Joo;Park, Jong Chul
    • Archives of Plastic Surgery
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    • v.32 no.2
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    • pp.143-148
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    • 2005
  • Chemotactic migration of bone forming cell, osteoblast, is an important event during bone formation, bone remodeling, and fracture healing. Migration of cells is mediated by adhesion receptors, such as integrins, that link the cell to extracellular matrix ligands, type I collagen, fibronectin, laminin and depend on interaction between integrin and extracellular ligand. Our study was designed to investigate the effect of extracellular matrix like fibronectin, laminin, type I collagen on migration of osteoblast. Migration distance and speed of MC3T3-E1 cell on extracellular matrix-coated glass were measured for 24 hours using 0.01% type I collagen, 0.01% fibronectin, 100 microliter/ml laminin. The migration distance and speed of MC3T3-E1 cell was compared using a video-microscopy system. To determine migration speed, cells were viewed with a 4 phase- contrast lens and video recorded. Images were captured using a color CCD camera and saved in 8-bit full-color mode. The migration distance on 0.01% type I collagen or 0.01% fibronectin was longer than that on $100{\mu}l/ml$ laminin-coated glass. The migration speed on fibronectin-coated glass was 68 micrometer/hour which was fastest. The migration speed on type I collagen-coated glass was similar with that on fibronectin-coated glass. The latter two migration speeds were faster than that on no-coated glass. On the other hand, the average migration speed on laminin-coated glass was 37micrometer/hour and not different from that of control group. In conclusion, the extracelluar matrix ligands such as type I collagen and fibronectin seem to play an important role in cell migration. The type I collagen or fibronectin coated scaffold is more effective for migration of osteoblast in tissue engineering process.

A Study on the Dynamic Response of Steel Highway Bridges Using 3-D Vehicle Model (3차원(次元) 차량(車輛)모델을 사용(使用)한 강도로교(鋼道路橋)의 동적응답(動的應答) 관(關)한 연구(硏究))

  • Chung, Tae Ju;Park, Young Suk
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.14 no.5
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    • pp.1055-1067
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    • 1994
  • This paper is presented to perform linear dynamic analysis of bridges due to vehicle moving on bridges. The road surface roughness and bridge/vehicle interaction are also considered. The bridge and vehicle are modeled as 3-D bridge and vehicle model, respectively. The road surface roughness of the roadway and bridge decks are generated from power spectral density(PSD) function for good road. The PSD function proposed by C.J. Dodds and J.D. Robson is used to describe the road surface roughness for good road condition. The vehicles are modeled as two nonlinear vehicle model with 7-D.O.F of truck and 12-D.O.F of tractor-trailer and the equations of motion of the vehicles are derived using Lagrange's equation. The main girder and concrete deck are modeled as beam and shell element, respectively and rigid link is used between main girder and concrete deck. The equations of motion of the vehicles are solved by Newmark ${\beta}$ method and the equations of the motion of the bridges are solved by mode-superposition procedures. The validity of the proposed procedure is demonstrated by comparing the results with the experimental data reported by the AASHO Road Test. The comparison shows that the agreement between experiment and theory is quite satisfactory.

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Vitamin B12 Model Complexes: Synthesis and Characterization of Thiocyanato Cobaloximes and Thiocyanato Bridged Dicobaloximes of O-donor Ligands: DNA Binding and Antimicrobial Activity (비타민 B12 모델 착물: O-주개 리간드인 Thiocyanato Cobaloximes 및 Thiocyanato로 연결된 Dicobaloximes의 합성 및 특성규명: DNA 결합 및 향균 활성)

  • Mustafa, Bakheit;Satyanarayana, S.
    • Journal of the Korean Chemical Society
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    • v.54 no.6
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    • pp.687-695
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    • 2010
  • Complexes of thiocyanato(L)cobaloximes where L is urea, acetamide, semicrabazide and formamide were synthesized and characterized. The reaction of thiocyanato (L) cobaloximes (SCNCo$(DH)_2$(L)) with benzyl (aquo) cobaloxime $PhCH_2Co(DH)_2(OH_2)$ was found to produce a series of thiocyanato bridged dicobaloximes of a general formula of $PhCH_2Co(DH)_2SCNCo(DH_2)(L)$. Evidence for formulation as dicobaloximes containing thiocyanato ligand bridges was obtained from infrared data which show $20-45cm^{-1}$ increase in vCN upon formation of the dicobaloxime from the corresponding terminal thiocyanocobaloxime (SCNCo$(DH)_2$(L)). Further characterization of these two series was done on the basis of ($^1H$,$^{13}C$)NMR, LCMS and elemental analysis. Anti-microbial activity of thiocyanato(L)cobaloximes and thiocyanato bridged dicobaloximes were screened against E. Coli. The DNA-binding behaviors of both monomers and dimers were investigated by spectroscopic methods and viscosity measurements. The results indicated that the dimer complexes bind with calf-thymus DNA in an intercalative mode via the terminal benzyl ring into the base pairs of DNA. It was observed that the monomer complexes did not interact with DNA. Fluorescence spectra for the interaction between thiocyanato bridged dicobaloximes and DNA were also studied.

Seismic Analysis of RC Subway Station Structures Using Finite Element Method (유한요소법을 이용한 철근콘크리트 지하철 정거장 구조물의 내진 해석)

  • Nam, Sang-Hyeok;Song, Ha-Won;Byun, Keun-Joo
    • Journal of the Korea Concrete Institute
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    • v.15 no.2
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    • pp.225-233
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    • 2003
  • Even though a lot of advanced researches on analysis, design, and performance evaluation of reinforced concrete (RC) under seismic action have been carried out, there has been only a few study on seismic analysis of underground RC structures surrounding soil medium. Since the underground RC structures interact with surrounding soil medium, a path-dependent soil model which can predict the soil response is necessary for analyzing behavior of the structure inside soil medium. The behavior of interfacial zone between the RC structure and the surrounding medium should be also considered for more accurate seismic analysis of the RC structure. In this paper, an averaged constitutive model of concrete and reinforcing bars for RC structure and path-dependent Ohsaki's model for soil are applied, and an elasto-plastic interface model having thickness is proposed for seismic analysis of underground RC structures. A finite element analysis technique is developed by applying aforementioned constitutive equations and is verified by predicting both static and dynamic behaviors of RC structures. Then, failure mechanisms of underground RC structure under seismic action are numerically derived through seismic analysis of underground RC station structure under different seismic forces. Finally, the changes of failure mode and the damage level of the structures are also analytically derived for different design cases of underground RC structures.

Mobile Robot Control using Smart Phone for internet of Things (사물인터넷 구축을 위한 스마트폰을 이용한 이동로봇의 제어)

  • Yu, Je-Hun;Ahn, Seong-In;Lee, Sung-Won;Sim, Kwee-Bo
    • Journal of the Korean Institute of Intelligent Systems
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    • v.26 no.5
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    • pp.396-401
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    • 2016
  • Owing to developments in the internet of things, many products have developed and various researches have processed. Smart home systems in Internet of things area are receiving attention from many people than the other areas. Autonomous mobile robots perform various parts in many industries. In this paper, a smart housekeeping robot was implemented using internet of things and an autonomous mobile robot. In order to make a smart housekeeping robot, Raspberry Pi, wireless USB camera, and uBrain robot of Huins Corp. is used. To control the robot, cell-phone connected with IP of Raspberry Pi, and then Raspberry Pi connected with uBrain robot using Bluetooth. a smart housekeeping robot was controlled using commands of a cell-phone application. If some user wants to move a robot automatically, we implemented that a robot can be chosen an autonomous driving mode from the user. In addition, we checked a realtime video using a cell-phone and computer. This smart housekeeping robot can help user check their own homes in real time.

The Effect of Resource Depletion on Deciding on Product Assortments Size (소비자의 자원고갈이 제품구색간 의사결정에 미치는 효과)

  • Cho, Yeon-Jin;Park, Cheong-Kyu;Lim, Hyun-Woo
    • Journal of Distribution Science
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    • v.14 no.3
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    • pp.85-91
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    • 2016
  • Purpose - Prior research has suggested that consumers typically prefer to have a larger number of options. However, preference of assortment size may depend on how depleted resources in consumers' mind are. Reduced capacity for self-regulation by resource depletion makes people rely on more intuitive and less effortful decision processing. When they are mentally depleted, people are likely to focus on the choice difficulty from large assortment, which leads to preference for the small assortment when they make a decision. It could be an important question potentially how being in a depleted mode through effortful self-regulation will influence on the evaluation of assortment size. To answer this questioner, we hypothesized that being engaged in self-regulation, as compared with not being engaged in self-regulation, will influence on the evaluation of product assortment size such as attractiveness, difficulty of choice, and anticipated regret. Research design, data, and methodology - In this study, we first manipulated self-regulatory resource availability using a self-regulation task (i.e., instructing participants to solve Sudoku puzzle vs. to solve diagram cube by filling any diagrams that they prefer into cube instead of number) and asked to indicate the difficulty of the tasks available to them ("How much difficulty did you feel when you complete the task?") Next, participants were asked to imagine that they were planning to buy a laptop at one of the two stores (small assortment: 6 options vs. large assortment: 30 options), both offering good quality of products. After reading the product descriptions, participants were instructed to consider all the information and choose a store that they would like to shop. Finally we measured the choice difficulty, evaluation of product assortments, and anticipated regret on a 7-point scale. We conducted two-way ANOVA in testing the main hypothesis that depleted consumers will show poorer subsequent self-control than non-depleted consumers when they make a decision in large assortment. Results - Compared with non-depleted participants, depleted participants showed the bigger difference from the degree of choice difficulty and product attractiveness between large and small assortments, but the result revealed only a significant interaction effect of resource depletion and assortment size on choice difficulty. Also depleted participants showed the smaller difference from the degree of anticipated regret between large and small assortments than non-depleted participants. Conclusion - Depleted individuals by a prior task are relatively effortless and intuitive form of choosing products so that they try to avoid making effortful trade-offs among choice difficulty such as large assortment, compare with non-depleted individuals. However, for anticipated regret, non-depleted individuals in small assortment anticipate more regret by excluding or at least restricting the possibility of buying attractive items or another kind of potential items than depleted individuals, regardless less choice difficulty in small option. To sum up, it is important to note that individuals are influenced by self-regulatory resources and their self-regulatory conditions contribute to the overall positive or negative impact of product assortment on choice.

Evaluation of Groundwater Quality Using Factor Aanlyses and Agrochemicals in an Agricultural Area (요인분석과 농약성분 특성에 의한 농업지역의 지하수 수질 평가)

  • Lee, Jeong-Hwan;Hamm, Se-Yeong;Kim, Kwang-Sung;Cheong, Jae-Yeol;Ryu, Sang-Min;Kim, Deuk-Ho;Kim, Hyun-Ji
    • Economic and Environmental Geology
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    • v.42 no.3
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    • pp.217-234
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    • 2009
  • This study characterized groundwater quality and the influence of agrochemicals in a part of Ilgwang-Myeon agricultural area in Gijang-Gun, Busan Metropolitan City, using factor analyses. From the 1st, 2nd, and 3rd analyses of groundwater samples, the mean concentrations of $Ca^{2+}$, $Na^+$, $Mg^{2+}$, $K^+$, $Zn^{2+}$, $Cu^{2+}$, $Fe^{2+}$, $Al^{3+}$, $NO_3\;^-$, $Cl^-$, $SO_4\;^{2-}$, $F^-$, and $SiO_2$ were higher in the 2nd analysis than the other analyses. Pesticide carbofuran and herbicide alachlor were detected at the wells more than a half of all the wells in the 2nd analysis but not in the 4th analysis. This fact may be explained by that a higher precipitation induced higher infiltration rate of contaminants into groundwater during the 2nd survey. According to R- and Q-mode factor analyses, and chemical composition, inorganic constituents excepting $SiO_2$, $HC0_3\;^-$-, and $F^-$ may be influenced by anthropogenic sources (manures, synthetic fertilizers, and domestic wastes), seawater as well as water-mineral interaction. A typical indicator of groundwater contamination, nitrate, exceeds around 4-5 times over the Korean standard for drinking water. Additionally, the influence of seawater diminishes from the seaside to inland.

A Study on the Moment Capacity of H-Section Flexural Members with Local Buckling (국부좌굴이 발생하는 H-형강 휨부재의 강도에 관한 연구)

  • Seo, Gun-Ho;Seo, Sang-Jung;Kwon, Young-Bong
    • Journal of Korean Society of Steel Construction
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    • v.23 no.6
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    • pp.647-657
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    • 2011
  • This paper describes the moment capacity of flexural members with local buckling based on a series of FE and experiment results. Thin-walled flexural members undergo local, lateral-torsional, or interactive buckling according to the section geometries and lateral boundary conditions. Flexural members with large width-to-thickness ratios in the flanges or the web may undergo local buckling before lateral-torsional buckling. Local buckling has a negative effect on the flexural strength based on the lateral-torsional buckling of flexural members. This phenomenon should be considered in the estimation of the flexural strength of thin-walled sections. Flexural members with various width-to-thickness ratios in their flanges and web were analyzed. Initial imperfections in the local buckling mode, and residual stresses, were included in the FE analyses. Simple bending moment formulae for flexural members were proposed based on the FE and test results to account for local and lateral-torsional buckling. The proposed bending moment formulae for the thin-walled flexural members in the Direct Strength Method use the empirical strength formula and the grosssection modulus. The ultimate flexural strengths predicted by the proposed moment formulae were compared with the AISC (2005), Eurocode3 (2003), and Korean Highway Bridge Design Specifications (2010). The comparison showed that the proposed bending moment formulae can reasonably predict the ultimate moment capacity of thin-walled flexural members.

Studies of Oxo-Nitrosyl Complexes(Ⅱ) Synthesis and Properties of Tungsten Oxo-Nitrosyl Complexes with Butylamidoxime Derivatives (산소-니트로실 착물의 연구 (제2보) 부틸아미드옥심 유도체의 텅스텐 산소-니트로실 착물의 합성과 특성)

  • Roh, Soo Gyun;Oh, Sang Oh
    • Journal of the Korean Chemical Society
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    • v.39 no.11
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    • pp.856-862
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    • 1995
  • The tungsten oxo-nitrosyl complexes (n-Bu4N)2[W5O12(NO)2{RC(NH2)NHO}2{RC(NH)NO}2] (R=(CH3)2CH, CH3CH2CH2, CH3SCH2) have been synthesized by the reactions of polyoxotungsten complex (n-Bu4N)2[W6O19] and tungsten dinitrosyl monomeric complex [W(NO)2(acac)(CH3CN)2](BF4) with butylamidoxime derivatives. The prepared complexes have been characterized by elemental analysis, infrared, UV-visible, 1H NMR and 13C NMR spectroscopy. The pentanuclear species was formed by the interaction of the electron-withdrawing {W(NO)2}2+ unit between the two dinuclear tungsten {W2O5}2+ cores. We can estimate to exist large proton interactions viewed from the four doublet in 1H NMR spectrum of (n-Bu4N)2[W5O12(NO)2{(CH3)2CHC(NH2)NHO}2{(CH3)2CHC(NH)NO}2]. We also drew informations of the two different coordination mode and symmetry of the complexes because two ligands appear in 13C NMR spectra instead of four. The {W(NO)2}2+ unit has been cis-form and C2v symmetry in geometric structure.

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Railway Governance and Power Structure in China

  • Lee, Jinjing
    • International Journal of Railway
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    • v.1 no.4
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    • pp.129-133
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    • 2008
  • Over the last $15{\sim}20$years, many countries have adopted policies of railway privatization to keep up with increasing competition from road and air transport. Although each country and case has its own history, market characteristics, political context as well as administrative process, railway privatizations (including railway restructure, concession etc.) in the west usually are accompanied with the establishment of new regulatory regimes. Therefore, railway governance has been innovating towards an interaction of government, regulator, industry bodies, user groups, trade unions and other interested groups within the regulatory framework. However, it is not the case in China. Although China had seen a partial privatization in some branch lines and is experiencing a much larger-scale privatization by establishing joint-ventures to build and operate high-speed passenger lines and implementing an asset-based securitization program, administrative control still occupies absolutely dominant position in the railway governance in China. Ministry of Railway (MOR) acts as the administrator, operator as well as regulator. There is no national policy that clearly positions railway in the transportation network and clarifies the role of government in railway development. There is also little participation from interested groups in the railway policy making, pricing, service standard or safety matter. Railway in China is solely governed by the mere executive agency. Efficiency-focused economic perspective explanation is far from satisfaction. A wider research perspective from political and social regime is of great potential to better explain and solve the problem. In the west, separation and constrains of power had long been established as a fundamental rule. In addition to internal separation of political power(legislation, execution and jurisdiction), rise of corporation in the 19th century and association revolution in the 20th century greatly fostered the growth of economic and social power. Therefore, political, social and economic organizations cooperate and compete with each other, which leads to a balanced and resonable power structure. While in China, political power, mainly party-controlled administrative power has been keeping a dominated position since the time of plan economy. Although the economic reform promoted the growth of economic power of enterprises, it is still not strong enough to compete with political power. Furthermore, under rigid political control, social organizations usually are affiliated to government, independent social power is still too weak to function. So, duo to the limited and slow reform in political and social regime in China, there is an unbalanced power structure within which political power is dominant, economic power expanding while social power still absent. Totally different power structure in China determines the fundamental institutional environment of her railway privatization and governance. It is expected that the exploration of who act behind railway governance and their acting strength (a power theory) will present us a better picture of railway governance as a relevant transportation mode. The paper first examines the railway governance in China and preliminarily establishes a linkage between railway governance and its fundamental institutional environment, i.e. power structure in a specific country. Secondly, the reason why there is no national policy in China is explored in the view of political power. In China, legislative power is more symbolic while party-controlled administrative power dominates political process and plays a fundamental role in Chinese railway governance. And then, in the part three railway finance reform is analyzed in the view of economic power, esp. the relationship of political power and economic power.

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