• 제목/요약/키워드: Interaction Surface

검색결과 2,465건 처리시간 0.025초

Silica-based Gel Filtration 크로마토그래피에서의 단백질-실리카 상호작용 (Protein-silica Interaction in Silica-based Gel Filtration Chromatography)

  • 최중갑;유경수
    • 약학회지
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    • 제35권6호
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    • pp.461-465
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    • 1991
  • Silica-based gel filtration chromatography has been used to characterize molecular weight of proteins. However, the molecular weight measured by this method was distorted by protein-silica interactions like hydrophobic and electrostatic forces. Therefore, we characterized protein-silica interaction using two forms of phytochrome (124 kDa) having different hydrophobicity and surface charge. PH and ionic strength affected the retention time of phytochrome suggesting that electrostatic force is the major interaction between protein and silica surface.

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A numerical simulation method for the flow around floating bodies in regular waves using a three-dimensional rectilinear grid system

  • Jeong, Kwang-Leol;Lee, Young-Gill
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제8권3호
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    • pp.277-300
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    • 2016
  • The motion of a floating body and the free surface flow are the most important design considerations for ships and offshore platforms. In the present research, a numerical method is developed to simulate the motion of a floating body and the free surface using a fixed rectilinear grid system. The governing equations are the continuity equation and Naviere-Stokes equations. The boundary of a moving body is defined by the interaction points of the body surface and the centerline of a grid. To simulate the free surface the Modified Marker-Density method is implemented. Ships advancing in regular waves, the interaction of waves by a fixed circular cylinder array and the response amplitude operators of an offshore platform are simulated and the results are compared with published research data to check the applicability. The numerical method developed in this research gives results good enough for application to the initial design stage.

후류가 익렬유동에 미치는 영향에 대한 실험적 연구 (Study of the Effects of Wakes on Cascade Flow)

  • 김형주;주원구;조강래
    • 유체기계공업학회:학술대회논문집
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    • 유체기계공업학회 1999년도 유체기계 연구개발 발표회 논문집
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    • pp.309-314
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    • 1999
  • This paper is concerned with the viscous interaction between rotor and stator The viscous interaction is caused by wakes from upstream blades. The cascade was composed with five blades and cylinders were placed to make wakes and their location was about 50 percent of blade chord upstream. The location of cylinders were varied in the cascade axis with 0, 20, 40, 60 and 80 percent of pitch length. The velocity distribution in the cascade passage were measured using single slanted hot-wire and the ones in the boundary layer using boundary probe. As a result, wakes decay more rapidly at suction surface and more slowly at pressure surface. And the measurement of momentum thickness of cascade shows that the momentum thickness is larger near the blade surface. From measurement of blade boundary layer, turbulent intensity is also larger near the blade surface because wakes collide the boundary layer And wakes make boundary layer thickness smaller and delay flow separation.

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터널 건설에 따른 지하수-지표수 상호 작용 및 영향에 관한 연구

  • 김태희;김영식;하규철;김구영;고동찬;양인제;홍순택
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2004년도 춘계학술발표회
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    • pp.839-846
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    • 2004
  • The objective of this study is the evaluation of the tunneling effect on the groundwater-surface water interaction. The designed tunnel line is laid beneath the Gapo-cheon, which runs throughout study area. And, the pre-evaluation of the tunnel-influence on the Gapo-cheon is urgently needed. However, it is very difficult to find out the similar domestic and/or foreign cases. In this study, we would exclude the numerical modeling technique with insufficient data. Instead of the evaluation of the tunneling effect on the groundwater-surface water interaction with the numerical modeling, we monitored the flow rate of surface water at various point. We measured the flow rate of surface water at 5 points. With the results of surface flow, we can conclude that 39% of flow rate in Gapo-cheon is contributed by the groundwater discharge, as baseflow.

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복합화약 원료들간의 표면특성 해석 (Analysis of surface interaction between filler and binder of PBXs)

  • 심정섭
    • 한국군사과학기술학회지
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    • 제4권1호
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    • pp.207-215
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    • 2001
  • Plastic bonded explosive(PBX) is mainly composed of the nitramine-ploymer compositions. PBX is characterized by high velocity and pressure of detonation, low vulnerability and good thermal stability. Many important applications of PBX require the good adhesion between nitramine crystals and the binder. For PBXs as well as propellants, where good mechanical properties are of great importance, dewetting therefore must be prevented by strong adhesion between filler-binder. Adhesion depends on surface characteristics of filler and binder. In order to design for better adhesion, an understanding of the surface properties of explosive and binder is required. The surface free energies are calculated from contact angle values by the method of Kaelble. Critical surface tension of solids are calculated by Zisman plot. Critical surface tension is a useful parameter for characterizing the wettability of solid surface. In this study, HMX and 3 kinds of copolymers are selected, since they are widely used in many plastic bonded explosives. The technical objective of this investigation is to predict the interaction between filler and binder from their surface free energies.

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Finite Element Analysis of Laser-Generated Ultrasound for Characterizing Surface-Breaking Cracks

  • Jeong Hyun Jo
    • Journal of Mechanical Science and Technology
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    • 제19권5호
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    • pp.1116-1122
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    • 2005
  • A finite element method was used to simulate the wave propagation of laser-generated ultrasound and its interaction with surface breaking cracks in an elastic material. Thermoelastic laser line source on the material surface was approximated as a shear dipole and loaded as nodal forces in the plane-strain finite element (FE) model. The shear dipole- FE model was tested for the generation of ultrasound on the surface with no defect. The model was found to generate the Rayleigh surface wave. The model was then extended to examine the interaction of laser generated ultrasound with surface-breaking cracks of various depths. The crack-scattered waves were monitored to size the crack depth. The proposed model clearly reproduced the experimentally observed features that can be used to characterize the presence of surface-breaking cracks.

가시화와 5공 프로브 측정을 통한 연장된 앞전을 갖는 편요된 델타형 날개에서의 와류 상호작용 관찰 (Observation of the Vortex Interaction over an Yawed Delta Wing with Leading Edge Extension by Flow Visualization and 5-hole Probe Measurements)

  • 손명환;이기영
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2001년도 추계학술대회논문집B
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    • pp.388-393
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    • 2001
  • An experimental study is conducted to investigate the interaction of vortices over a delta wing with leading edge extension(LEX) through the off-surface flow visualization and the 5-hole probe measurements of the wing wake region. Especially, the application of a new visualization technique is employed by ultrasonic humidifier water droplet and laser beam sheet. The results, both the off-surface visualization and the 5-hole probe, show that LEX tends to stabilize the vortices of the delta wing up to the high angle of attack even though the model is yawed. With increasing yaw, the windward leading edge vortex moves inward, and closer to the wing surface, while the leeward vortex moves outwards and away from the wing surface. The vortex interaction is promoted in the windward side, and is delayed in the leeward side.

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표면 근전도 신호를 이용한 실시간 상지부 동작 예측을 통한 인간-기계 상호작용 (Human-Machine Interaction based on a Real-time Upper Limb Motion Prediction using Surface Electromyography)

  • 권순철;김정
    • 한국HCI학회:학술대회논문집
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    • 한국HCI학회 2009년도 학술대회
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    • pp.418-421
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    • 2009
  • 본 논문은 표면 근전도 신호(sEMG)를 이용해 상지부의 동작을 실시간으로 예측하고 이를 기반으로 한 인간-기계 상호작용(Human-machine interaction)에 관한 것이다. 사용자의 상지부에 위치한 5 곳의 근육에서 수집하는 근전도 신호와 인공신경회로망(arfiticial neural network) 알고리즘을 이용하여 상지부 동작을 실시간으로 예측하였고, 기계팔(manipulator)이 예측된 동작을 좇아 움직이도록 제어되었다. 이때, 사용자가 기계팔의 끝단(end-effector)과 접촉해 있는 상태에서 상지부 동작은 2 차원 평면 위에서 이루어지도록 제한된다. 본 논문이 제안하는 동작 예측 방법과 인체 각도계(goniometer)를 이용한 경우의 상호 작용 실험을 통해, 동작 예측을 통한 인간-기계 상호 작용의 성능을 알아보았다. 실험 결과로부터, 제안된 실시간 동작 예측 방법을 이용하여 사용자와 기계의 상호 작용 시스템을 구현할 수 있음을 알 수 있다.

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SVM 모델을 이용한 3차원 패치 기반 단백질 상호작용 사이트 예측기법 (Prediction of Protein-Protein Interaction Sites Based on 3D Surface Patches Using SVM)

  • 박성희
    • 정보처리학회논문지D
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    • 제19D권1호
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    • pp.21-28
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    • 2012
  • 모노머 단백질의 상호작용 사이트 예측은 기능을 알지 못하는 단백질에 대해서 이것과 상호작용하는 단백질로부터 기능을 예측하거나 단백질 도킹을 위한 검색 공간의 감소에 중요한 역할을 한다. 그러나 상호작용사이트 예측은 대부분 단백질 상호작용이 세포 내에서 순간적 반응에 일어나는 약한 상호작용으로 실험에 의한 3차원 결정 구조 식별의 어려움이 따르며 이로 인해 3차원의 복합체 데이터가 제한적으로 양산된다. 이 논문에서는 모노머 단백질의 3차원 패치 계산을 통하여 구조가 알려진 복합체의 상호작용사이트와 비상호작용사이트에 대한 패치 속성을 추출하고 이를 기반으로 Support Vector Machine (SVM) 분류기법을 이용한 예측 모델 개발을 제시한다. 타겟 클래스의 데이터 불균형 문제 해결을 위해 under-sampling 기법을 이용한다. 사용된 패치속성은 2차 구조 요소와 아미노산 구성으로부터 총 9개가 추출된다. 147개의 단백질 복합체에 대해서 10 fold cross validation을 통해서 다양한 분류모델의 성능 평가를 하였다. 평가한 분류 모델 중 SVM은 92.7%의 높은 정확성을 보이고 이를 이용하여 분류 모델을 개발하였다.

실린더 형태의 나노와이어와 표면 사이의 응착력 평가를 위한 분자동역학 시뮬레이션 연구 (Investigation of Adhesion force between Cylindrical Nanowire and Flat Surface through Molecular Dynamics Simulation)

  • 김현준
    • Tribology and Lubricants
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    • 제31권6호
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    • pp.264-271
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    • 2015
  • Adhesion force of nanomaterials such as nanoparticle, nanowire, and nanorods should be significantly considered for its mechanical applications. However, examination of the adhesion force is limited since it is technically challenging to carry out experiments with such small objects. Therefore, in this work, molecular dynamics simulation (MDS) was conducted to determine the adhesion force between a nanowire and a flat surface, which could not be readily assessed through experiments. The adhesion force of a cylindrical-shaped nanowire was assessed by performing MDS and applying an equation of Van der Waals interaction. Simulation was conducted in two steps: indentation of a spherical tip on the flat surface and indentation of a cylinder on the flat surface, because the purpose of the simulation was comparing the results of the simulation and calculation of the Van der Waals interaction equation. From the simulation, Hamaker constant used for the equation of Van der Waals interaction was determined to be 2.93 °ø 10?18 J. Using this constant, the adhesion force of the nanowire on the flat surface was readily estimated by calculating Van der Waals equation to be approximately 65~89 nN with respect to the diameter of the nanowire. Moreover, the adhesion force of the nanowire was determined to be 52~77 nN from the simulation It was observed that there was a slight discrepancy (approximately 15~25%) between the results of the simulation and the theoretical calculation. Thus, it was confirmed that the calculation of Van der Waals interaction could be utilized to assess the adhesion force of the nanowire.