• 대한한의학방제학회지
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• 제16권2호
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• pp.91-100
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• 2008

Background and Objectives : There are three kinds of formulas for purging the kidney to cure its sthenic syndrome based on the types of preparation formulas : Sashintang, Sashinhwan and Sashinsan. There are 4 kinds of Sashintang, 1 kind of Sashinhwan and 1 kind of Sashinsan. Combination of herbal medicines, carried out in formulas for purging the kidney, consists of various kinds depending on medical scientists' personal experience in medical treatment without any general principles, which makes it difficult to apply it to clinical use. The objectives of this study lie in theoretical establishment of Pyeongshintang for curing the sthenic syndrome of kidney through analyzing the component medicines and combination principles of Hyeongok's Pyeongshintang, and furthermore, maximizing the clinical use of Pyeongshintang. Methods : This study analyzed the component medicines and combination principles of Hyeongok's Pyeongshintang based on the theory for properties and tastes of herbal medicines from the "Yellow Emperor's Canon of Internal Medicine", the theory for principal herbal medicine, assistant herbal medicine, adjuvant herbal medicine, dispatcher herbal medicine, and the five elements doctrine. Hyeongok's Pyeongshintang is an odd prescription, composed of 7 kinds of ingredients : No.1 Rhizoma Alismatis (2don;7.5g), No.2 Poria (1don;3.75g), No.3 Radix Paeoniae Alba (1don), No.4 Fructus Chaenomelis (1don), No.5 Polyporus (1don), No.6 Cortex Cinnamomi (1don), and No.7 Radix Glycyrrhizae (1don) Results : There are three methods for curing the sthenic syndrome of kidney according to the five elements doctrine : purging the kidney, purging the liver and invigorating the spleen. First, if you suffer from the sthenic syndrome of the kidney, you need to purge your kidney. There are two available methods, including taste and property purgation according to the theory for properties and tastes of herbal medicines. They each imply the salty taste and the hot property purge the kidney. In the case of taste purgation, two herbal medicines with salty taste, Rhizoma Alismatis and Poria, are combined into the principal and assistant herbal medicine, respectively. For property purgation, two herbal medicines with the hot property, Polyporus and Cortex Cinnamomi, are combined into adjuvant herbal medicines. Secondly, if you suffer from the sthenic syndrome of the kidney, you need to purge your liver which is child in the mother-child relationship in inter-promotion among the five elements. There are two methods to purge the liver, including taste and property purgation according to the theory for properties and tastes of herbal medicines. They each mean the sour taste and the cool property purge the liver. Therefore, it is important to use sour herbal medicines for taste purgation and cool ones for property purgation. Both sour and cool herbal medicines, Radix Paeoniae Alba and Fructus Chaenomelis, are combined into adjuvant herbal medicines. Lastly, if you suffer from the sthenic syndrome of the kidney, you need to invigorate your spleen which is an element being surpassed in the relationship between the elements surpassed and ones not surpassed in inter-restraint among the five elements. There are two methods to invigorate the spleen, which include taste and property invigoration according to the theory for properties and tastes of herbal medicines. Taste invigoration means to invigorate the spleen with sweet taste and property invigoration to invigorate the spleen with warm property. Therefore, it is important to use sweet herbal medicines for taste invigoration and warm ones for property invigoration. Both sweet and warm herbal medicines, Polyporus and Cortex Cinnamomi, were combined to invigorate the spleen and purge the kidney. In addition, Radix Glycyrrhizae are combined as dispatcher herbal medicine, harmonizing all the herbal medicines composing the formula. Conclusions : First, to cure the sthenic syndrome of the kidney, the methods of purging the kidney and the liver, and invigorating the spleen should be used according to the five elements doctrine. Secondly, herbal medicines appropriate for those treatment methods should be chosen according to the theory for properties and tastes of herbal medicine and thirdly, the combination of those herbal medicines should be carried out according to the theory for principal herbal medicine, assistant herbal medicine, adjuvant herbal medicine, dispatcher herbal medicine. As a good example, Hyeongok's Pyeongshintang is combined according to the above theories. In conclusion, this formula was created by applying to the theory for properties and tastes of herbal medicines.

• 동의생리병리학회지
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• 제21권3호
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• pp.591-595
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• 2007

There are eight kinds of formulas for invigorating the liver to cure its asthenic syndrome based on the types of preparation formulas Began-tang, Boganhwan, Bogansan, Bogandan, Boganeum, Boganjoo, Boganjeon and Bogango. Another formula called Bocheonghwan is to invigorate the green colour of liver. There are 22 kinds of Bogan-tang, 12 kinds of Boganhwan, 25 kinds of Bogansan, one kind of Bogandan, one kind of Boganeum, one kind of Boganjoo, one kind of Boganjeon, one kind of Bogango, and two kinds of Bocheonghwan. Combination of herbal medicines, carried out in formulas for invigorating the liver, consists of various kinds depending on medical scientists' personal experience in medical treatment without any general principles, which makes it difficult to apply it to clinical use. The objectives of this study lie in theoretical establishment of Bogan-tang for curing the asthenic syndrome of liver through analyzing the component medicines and combination principles of Hyeongok's Bogan-tang, and furthermore, maximizing the clinical use of Began-tang. This study analyzed the component medicines and combination principles of Hyeongok's Bogan-tang based on the theory for properties and tastes of herbal medicines from the ${\ulcorner}$yellow Emperor's Canon of Internal Medicine${\lrcorner}$ , the theory for principal herbal medicine, assistant herbal medicine, adjuvant herbal medicine, dispatcher herbal medicine, and the five elements doctrine. Hyeongok's Began-tang is an odd prescription, composed of 7 kinds of ingredients No.1 Radix Angelicas Sinensis (2don;7.5g), No.2 Rhizoma Chuanxiong (1don;3.75g), No.3 Radii Polygoni Multiflori (1don), No.4 Fructus Lycii (1don), No.5 Cortex Cinnamomi (1don), No.6 Rhizoma Gastrodiae (1don), and No.7 Radix Glycyrrhizae (1don). There are three methods for curing the asthenic syndrome of liver according to the five elements doctrine invigorating the liver, invigorating the kidney and purging the lung. First, if you suffer from the asthenic syndrome of the liver, you need to invigorate your liver. There are two available methods, including taste and property invigoration according to the theory for properties and tastes of herbal medicines. They each imply the pungent taste and the warm property invigorate the liver. In the case of taste invigoration, two herbal medicines with pungent taste, Radix Angelicas Sinensis and Rhizoma Chuanxiong, are combined into the principal and assistant herbal medicine, respectively. For property invigoration, two herDal medicines with the warm property, Cortex Cinnamomi and Rhizoma Gastrodiae, are combined into adjuvant herbal medicines. Secondly, if you suffer from the asthenic syndrome of the liver, you need to invigorate your kidney which is mother in the mother-child relationship in inter-promotion among the five elements. There are two methods to invigorate the kidney, including taste and property invigoration according to the theory for properties and tastes of herbal medicines. They each mean the bitter taste and the cold property invigorate the kidney. Therefore, it is important to use bitter herbal medicines for taste invigoration and cold ones for property invigoration. Both Differ and cold herbal medicines, Radix Polygoni Multiflori and Fructus Lycii, are combined into adjuvant herbal medicines. Lastly, if you suffer from the asthenic syndrome of the liver, you need to purge your lung which is an element being surpassed in the relationship between the elements surpassed and ones not surpassed in inter-restraint among the five elements. There are two methods to purge the lung, which include taste and property invigoration according to the theory for properties and tastes of herbal medicines. Taste invigoration means to purge the lung with pungent taste and property invigoration to purge the lung with warm property. Therefore, it is important to use pungent herbal medicines for taste invigoration and warm ones for property invigoration. Both pungent and warm herbal medicines, Radix Angelicas Sinensis and Rhizoma Chuanxiong, were combined to invigorate and purge the lung. In addition, Radix Glycyrrhizae are combined as dispatcher herbal medicine, harmonizing all the herbal medicines composing the formula. First, to cure the asthenic syndrome of the liver, the methods of invigorating the liver and the kidney, and purging the lung should be used according to the five elements doctrine. Secondly, herbal medicines appropriate for those treatment methods should be chosen according to the theory for properties and tastes of herDal medicine and thirdly, the combination of those herbal medicines should be carried out according to the theory for principal herbal medicine, assistant herbal medicine, adjuvant herbal medicine, dispatcher herbal medicine. As a good example, Hyeongok's Bogan-tangon is combined according to the above theories. In conclusion, this formula was created by applying to the theory for properties and tastes of herbal medicines.

• Korean Journal of Radiology
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• 제23권4호
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• pp.455-465
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• 2022

Objective: To compare the reproducibility and performance of quantitative metrics between ZOOMit and conventional intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) in the diagnosis of early- and mid-stage Sjögren's syndrome (SS). Materials and Methods: Twenty-two patients (mean age ± standard deviation, 52.0 ± 10.8 years; male:female, 2:20) with early- or mid-stage SS and 20 healthy controls (46.9 ± 14.6 years; male:female, 7:13) were prospectively enrolled in our study. ZOOMit IVIM and conventional IVIM MRI were performed simultaneously in all individuals using a 3T scanner. Quantitative IVIM parameters - including tissue diffusivity (D), pseudodiffusion coefficient (D^*), and perfusion fraction (f) - inter- and intra-observer reproducibility in measuring these parameters, and their ability to distinguish patients with SS from healthy individuals were assessed and compared between ZOOMit IVIM and conventional IVIM methods, appropriately. MR gland nodular grade (MRG) was also examined. Results: Inter- and intra-observer reproducibility was better with ZOOMit imaging than with conventional IVIM imaging (ZOOMit vs. conventional, intraclass correlation coefficient of 0.897-0.941 vs. 0.667-0.782 for inter-observer reproducibility and 0.891-0.968 vs. 0.814-0.853 for intra-observer reproducibility). Significant differences in ZOOMit f, ZOOMit D^*, D^*, conventional D^*, and MRG between patients with SS and healthy individuals (all p < 0.05) were observed. ZOOMit D^* outperformed conventional D^* in diagnosing early- and mid-stage SS (area under receiver operating curve, 0.867 and 0.658, respectively; p = 0.002). The combination of ZOOMit D^*, MRG, and ZOOMit f as a new diagnostic index for SS, increased diagnostic area under the curve to 0.961, which was higher than that of any single parameter (all p < 0.01). Conclusion: Considering its better reproducibility and performance, ZOOMit IVIM may be preferred over conventional IVIM MRI, and may subsequently improve the ability to diagnose early- and mid-stage SS.

• 한국음향학회지
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• 제23권4호
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• pp.303-308
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• 2004

본 논문에서는 전력 증폭기의 선형화를 위해 제안된 feed-forward 선형화 방식을 IMT-2000용 송신 시스템에 적용한 새로운 송신 시스템 구조를 제안한다. 이 시스템에서 feed-forward 구조는 왜곡 성분을 비교하고 제거하기 위해 보조신호(reference signal)을 필요로 하는데, 이 보조신호는 무시할 정도로 낮은 왜곡을 갖도록 낮은 입력 동작 범위에서 동작하는 두 번째 변조기에서 만들어 진다. 이런 구조로 한 결과송신 시스템에서 증폭기뿐만 아니라 변조기의 왜곡을 줄일 수 있다는 큰 장점이 있다. 본 논문의 시스템은 Agilent 社의 EEsoft ADS ver.2002를 사용하여 설계하였으며, 입력은 1.98GHz 주파수 대역에서 2MHz의 주파수 간격을 갖는 2-tone으로 하였고, 약 49.95dB의 IMD 개선 특성을 얻어, 본 논문에서 제안하는 시스템은 간단함과 선형성을 동시에 제공할 수 있다는 것을 입증하였다.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2011년도 정기총회 및 추계학술대회 논문집
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• pp.1607-1614
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• 2011

As the connection between spread footing and pile is very important structural connection, it acts as the inter-loading medium to transfer the rail loads applied by superstructure to ground through the body pile of foundation. The experimental study is the method how to reinforce the pile cap between steel pile and footing utilizing perfobond plate with protruding keys. It were experimented on the compression punching tests and bending moment tests against the vertical loading and horizontal loadings acting on head of steel tube pipe. As a result, the tension capacity of the perfobond plate exhibited the superior performance due to the interlocking or dowel effects by the sheared keys of perfobond plate, and there were showing the sufficient strength and ductile capacity against the bending moment of horizontal loading tests. Therefore, it is judged that "the embedded method of perfobond plate in pile cap and footing" which is utilizing the shear connection of perfobond plate with protruding keys has a sufficient structural stability enough to be replaced with the current specification of reinforced method of pile cap with vertically deformed rebar against the vertical compression loads and bending moments that are able to occur in the combination structure of steel pile and the footing foundation.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제7권1호
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• pp.99-118
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• 2013

Electrocardiograms (ECGs) are widely used by clinicians to identify the functional status of the heart. Thus, there is considerable interest in automated systems for real-time monitoring of arrhythmia. However, intra- and inter-patient variability as well as the computational limits of real-time monitoring poses significant challenges for practical implementations. The former requires that the classification model be adjusted continuously, and the latter requires a reduction in the number and types of ECG features, and thus, the computational burden, necessary to classify different arrhythmias. We propose the use of adaptive learning to automatically train the classifier on up-to-date ECG data, and employ adaptive feature selection to define unique feature subsets pertinent to different types of arrhythmia. Experimental results show that this hybrid technique outperforms conventional approaches and is therefore a promising new intelligent diagnostic tool.

• 대한기계학회논문집A
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• 제24권1호
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• pp.156-162
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• 2000

Sensitized STS 304 stainless steel crack growth rate(CGR) in high temperature water was investigated under trapezoidal wave loading test using fracture mechanics techniques. The CGR, due to stress corrosion cracking(SCC), were systematically measured as a function of the stress intensity factor and stress. holding time under trapezoidal wave loading. In high temperature water, CGR was enhanced by a synergistic effects in combination with an aggressive environment and mechanical damage. The CGR, $(da/dN)_{env}$ was basically described as a summation of the environmentally assisted crack growth rate $(da/dN)_{SCC}$, $(da/dN)_{CF}$ and fatigue crack growth rate in air $(da/dN)air,. The CGR, $(da/dN)_{env}$, increased linearly with increasing stress holding time. The CGR, $(da/dN)_{SCC}$ decreased linearly with increasing stress holding time. Fracture surface mode varied from trans-granular cracking to inter-granular cracking with increasing stress holding time.

• Journal of Information Technology Applications and Management
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• 제18권2호
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• pp.1-21
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• 2011

In this era of convergence, which is characterized by the integration and combination of technology and industries, broadcasting and communications, offline and online, and devices and services, the content industry is also experiencing rapid changes including inter-genre exchange, the creation of new industries, and customized demand. Specifically, IT-based digital content industries such as the online game, e-book, mobile contents and web portal industries are no longer restricted to the boundaries of video, music and games but are being expanded into the realms of education, medicine, fashion and sports thanks to CT innovation of 3D, CG, AR/VR, VFX, etc. As such, various countries have come to recognize the convergent content industry as a new growth engine that will pick up where the IT industry left off, and are forming policies for its development accordingly. This research aims to optimize the system of content taxonomy which is currently genre-focused and unable to support technological development and convergence, and to discover and select star contents to be rigorously developed with governmental support. In this paper, 20 star contents in 8 areas were selected, and these are expected to create tremendous cultural and economic value through ongoing technological and industrial development.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2005년도 BIOINFO 2005
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• pp.243-248
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• 2005

도메인 조합에 기반한 단백질 상호작용 예측 기법은 효모와 같은 특정 종에 대하여 우수한예측 정확도를 보이는 것으로 알려졌으나, 인간과 같은 고등 생명체의 단백질에 대한 상호작용 예측을 수행하기 위하여는 여러종에 대한 기법의 적절성검증과 최적의 학습집단 구성 방안에 대한 연구가 선행되어야 한다. 본 논문에서는, 초파리 단백질을 이용한 예측 정확도 검증으로 도메인 조합 기법의 일반화 가능성을 타진 하고 이종간의 상호작용 예측실험 및 정확도 검증을 통하여 비교적 연구가 덜 되어진 종의 단백질 상호작용 예측을 위한 학습집단 구성 방법에 대하여 기술한다. 초파리 실험에서는 10351개의 상호작용이 있는 단백질 쌍 가운데, 80%와 20%를 각각 학습집단 및 실험집단으로 사용하였으며, 상호작용이 없는단백질 쌍의 학습집단은 1배에서 5배까지 변화시키면서 예측 정확도를 관찰하였다. 이 결과77.58%의 민감도와 92.61%의 특이도를 확인하였다. 이종간의 상호작용 예측 실험은 효모, 초파리, 효모, 초파리에 해당하는 학습집단 각각을 바탕으로 Human, Mouse, E. coli, C. elegans 등의 단백질 상호작용 예측을 수행하였다. 실험 곁과 학습집단의 도메인이 실험집단의 도메인과 많이 겹칠수록 높은 정확도를 보여주었으며, 도메인 집단간의 유사도를 나타내기 위해 고안한 Domain Overlapping Rate(DOR) 는 상호작용 예측 정확도의 중요한 요소임을 찾아내었다.

• 정보처리학회논문지D
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• 제14D권1호
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• pp.89-96
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• 2007

컴포넌트 재사용을 위해 다양한 분류 방법들이 개발되어 왔다. 이러한 분류 방법들은 사용자가 필요로 하는 컴포넌트들을 쉽고 빠르게 접근하는 것을 돕는다. 전통적인 분류 방법들은 분류 구조 생성을 위한 도메인 분석 노력, 컴포넌트 사이의 관계 표현, 도메인 진화에 따른 분류 구조 유지 보수의 어려움, 그리고 한정된 도메인 적용과 같은 문제들을 포함한다. 본 논문은 이러한 문제들을 언급하기 위해 복합 클러스터 분석 기반의 컴포넌트 분류 방법에 대해 묘사한다. 안정적인 분류 구조 자동 생성을 위해 계층 클러스터 분석 방법과 새로운 컴포넌트의 자동 분류에 대해 비계층 클러스터 분석 개념은 결합된다. 제안된 방법에 의해 생성된 클러스터 정보는 관련 컴포넌트들에 대한 도메인 분석 과정을 지원할 수 있다.