• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.9
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• pp.1947-1954
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• 2012

The first frame is encoded in intra mode which generates a larger number of bits. In addition, the first frame is used for the inter mode encoding of the following frames. Thus the initial QP for the first frame affects the first frame as well as the following frames. Traditionally, the initial QP is determined among four constant values only depending on the bpp. In the case of low bit rate video coding, the initial QP value is fixed to 40 regardless of the output bandwidth. Although this initialization scheme is simple, yet it is not accurate enough. An accurate initial QP prediction scheme should not only depends on bpp but also on the complexity of the video sequence and the output bandwidth. In the proposed scheme, we determine the initial QP according to the ratio of the first frame to the total bits allocated to a GOP. To estimate the QP of the allocated bits, Rate-QP model is used. It is shown by experimental results that the new algorithm can predict the optimal initial QP more accurately and generate the PSNR performance better than that of the existing JVT algorithm.

• Molecules and Cells
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• v.25 no.2
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• pp.265-271
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• 2008

Single nucleotide polymorphisms (SNPs) are the most common form of human genetic variation. Non-synonymous SNPs (nsSNPs) change an amino acid. Organic anion transporters (OATs) play an important role in eliminating or reabsorbing endogenous and exogenous organic anionic compounds. Among OATs, hOAT4 mediates high affinity transport of estrone sulfate and dehydroepiandrosterone sulfate. The rapid bone loss that occurs in post-menopausal women is mainly due to a net decrease of estrogen. In the present study we searched for SNPs within the exon regions of hOAT4 in Korean women osteoporosis patients. Fifty healthy subjects and 50 subjects with osteoporosis were screened for genetic polymorphism in the coding region of SLC22A11 (hOAT4) using GC-clamp PCR and denaturing gradient gel electrophoresis (DGGE). We found three SNPs in the hOAT4 gene. Two were in the osteoporosis group (C483A and G832A) and one in the normal group (C847T). One of the SNPs, G832A, is an nsSNP that changes the $278^{th}$ amino acid from glutamic acid to lysine (E278K). Uptake of [$3^H$] estrone sulfate by oocytes injected with the hOAT4 E278K mutant was reduced compared with wild-type hOAT4. Km values for wild type and E278K were $0.7{\mu}M$ and $1.2{\mu}M$, and Vmax values were 1.8 and 0.47 pmol/oocyte/h, respectively. The present study demonstrates that hOAT4 variants can causing inter-individual variation in anionic drug uptake and, therefore, could be used as markers for certain diseases including osteoporosis.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.44 no.5
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• pp.12-19
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• 2007

This paper presents an ASIP(Application Specific Instruction Set Processor) for implementation of H.264/AVC, called VSIP(Video Specific Instruction-set Processor). The proposed VSIP has novel instructions and optimized hardware architectures for specific applications, such as intra prediction, in-loop deblocking filter, integer transform, etc. Moreover, VSIP has hardware accelerators for computation intensive parts in video signal processing, such as inter prediction and entropy coding. The VSIP has much smaller area and can dramatically reduce the number of memory access compared with commercial DSP chips, which result in low power consumption. The proposed VSIP can efficiently perform in real-time video processing and it can support various profiles and standards.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.2C
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• pp.193-202
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• 2010

In this paper, we propose a fast algorithm that can reduce the complexity for inter mode decision of the H.264 encoder. The main idea consists of two techniques. The first one is the technique early terminating mode decision process. We focused on the skip and $16{\times}16$ mode because these modes occupies the largest portion in most of sequences. The second one is the technique skipping unnecessary $8{\times}8$ modes. The time consumption caused by the $8{\times}8$ mode is very considerable. Therefore if we can extract the unnecessary $8{\times}8$ mode calculation well, a large amount of time can be saved in total encoding process. The experimental results show that the proposed algorithm can achieve up to 43% speed up ratio with insignificant PSNR loss. The increase of total bits encoded is also not noticeable.

• The Journal of the Acoustical Society of Korea
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• v.32 no.2
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• pp.124-130
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• 2013

The performance of underwater acoustic communication system is sensitive to the ISI(Inter-Symbol Interference) due to delay spread develop of multipath signal propagation. The equalizer is used to combat the ISI. In this paper, the performances of underwater acoustic communication with turbo equalizer were evaluated by real data collected in Korean littoral sea. As a result, when one iterative decoding using turbo equalizer is applied, the performance was improved 1.5 dB than the case of the non-iterative equalizer at BER $10^{-4}$. In the case of two or three iterations the performance was enhanced about 3.5 dB, but the performance wasn't improved any more in the case of more than three times.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37 no.6A
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• pp.420-425
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• 2012

A forward error correction (FEC) coding techniques is one of time diversity techniques with which the effect of channel impairments due to noise and fading are spreaded over independently, and thus the performance could be improved. Therefore, the performance of the FEC scheme can be maximized if we minimize the correlation of channel information across over a codeword. In this paper, we propose a block turbo code with the maximized time diversity effect which may be reduced due to utilization of high order modulation schemes and due to transmission over a comparatively fast fading environment. Especially, we propose a very simple formula to calculate the address of coded bit allocation, and thus we do not need any additional outer interleavers, i.e., inter-codeword interleavers. The simulation resuts investigated in this paper reveal that the proposed scheme can provide the performance gain of more than a few decibels compared to the conventional schemes.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.11C
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• pp.1541-1550
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• 2004

In this paper, we propose an advanced hardware architecture for fast multi-resolution motion estimation of the video coding standard MPEG-1,2 and MPEG-4 AVC. We describe the algorithm and derive hardware architecture emphasizing the importance of area for low cost and fast operation by using the shared memory, the special ram architecture, the motion vector for 4 pixel x 4 pixel, the spiral search and so on. The proposed architecture has been verified by ARM-interfaced emulation board using Excalibur Altera FPGA and also by ASIC synthesis using Samsung 0.18 m CMOS cell library. The ASIC synthesis result shows that the proposed hardware can operate at 140 MHz, processing more than 1,100 QCIF video frames or 70 4CIF video frames per second. The hardware is going to be used as a core module when implementing a complete MPEG-4 AVC video encoder ASIC for real-time multimedia application.

• The Korean Journal of Physiology and Pharmacology
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• v.19 no.4
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• pp.319-325
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• 2015

Among solute carrier proteins, the organic anion transporters (OATs) play an important role for the elimination or reabsorption of endogenous and exogenous negatively charged anionic compounds. Among OATs, SLC22A9 (hOAT7) transports estrone sulfate with high affinity. The net decrease of estrogen, especially in post-menopausal women induces rapid bone loss. The present study was performed to search the SNP within exon regions of SLC22A9 in Korean females with osteoporosis. Fifty healthy controls and 50 osteoporosis patients were screened for the genetic polymorphism in the coding region of SLC22A9 using GC-clamped PCR and denaturing gradient gel electrophoresis (DGGE). Six SNPs were found on the SLC22A9 gene from Korean women with/without osteoporosis. The SNPs were located as follows: two SNPs in the osteoporosis group (A645G and T1277C), three SNPs in the control group (G1449T, C1467T and C1487T) and one SNP in both the osteoporosis and control groups (G767A). The G767A, T1277C and C1487T SNPs result in an amino acid substitution, from synonymous vs nonsynonymous substitution arginine to glutamine (R256Q), phenylalanine to serine (F426S) and proline to leucine (P496L), respectively. The Km values and Vmax of the wild type, R256Q, P496L and F426S were 8.84, 8.87, 9.83 and $12.74{\mu}M$, and 1.97, 1.96, 2.06 and 1.55 pmol/oocyte/h, respectively. The present study demonstrates that the SLC22A9 variant F426S is causing inter-individual variation that is leading to the differences in transport of the steroid sulfate conjugate (estrone sulfate) and, therefore this could be used as a marker for certain disease including osteoporosis.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.8
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• pp.18-24
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• 2017

The process of transmitting messages through a medium with a limited bandwidth or channel dispersion inevitably involves signal distortion and noise influxes, resulting in the degradation of transmission quality due to the inter-symbol interference and additional noise, which increases the error rate of the received symbols. The main role of the equalizer is to remove the channel distortion and noise from the received signal to recover the transmitted messages. A number of studies on the equalizer composed of a combination of linear filter and error control coding have shown that they played a key role in enhancing the transmission efficiency, which is essential for digital communication. This paper proposes a new algorithm to correct the residual symbol errors in the message signal. In general, equalizer performance improvement algorithms were developed to improve the initial convergence speed or steady-state error. In this paper, however, the equalizer input signal was reconstructed using the equalizer decision symbols and the channel estimates to directly correct the decision errors by analyzing the statistical characteristics of the difference signal between the actual received signal and the reconstructed signal.

• Journal of Korea Multimedia Society
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• v.10 no.5
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• pp.642-651
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• 2007

Recently, digital convergence, whose core demand is OSMU (One Sourse Multi Use),has been the main topic in e-learning domain and industry. However, the existing web learning content and the new resource developed toprovide contents to different learning environment must be processed to adapt the new learning settings, which causes the cost and time problem, So in this paper we design and implement a Java based SCORM content transcoding system which can transcode the SCORM-based learning content into MHP-based DiTV content in order to adapt t-learning environment using DiTV, which is closer to our real life. Using this system which has ability of inter-operation, reuse, highly-use, the problem mentioned above can be solved well. Moreover, it is possible for a learner who is not familiar with computer to study using DiTV instead of PC.