• 한국분말재료학회지
• /
• 제13권2호
• /
• pp.124-128
• /
• 2006

In recent years, equal channel angular pressing (ECAP) has been the subject of intensive study due to its capability of producing fully dense samples having a ultrafine grain size. In this paper, the ECAP process was applied to metallic powders in order to achieve both powder consolidation and grain refinement. In the ECAP process for solid and powder metals, knowledge of the internal stress, strain and strain rate distribution is fundamental to the determination of the optimum process conditions for a given material. The properties of the ECAP processed solid and powder materials are strongly dependent on the shear plastic deformation behavior during ECAP, which is controlled mainly by die geometry, material properties, and process conditions. In this study, we investigated the consolidation, plastic deformation and microstructure evolution behaviour of the powder compact during ECAP.

• 한국화재소방학회논문지
• /
• 제23권5호
• /
• pp.173-180
• /
• 2009

최근 도시의 밀집화, 다양화, 대형화에 따라 소방산업은 첨단소방기술이 요구되어지고 있어 점차 생산집약형 산업에서 지식기반산업으로 전환이 시도 되어지고 있다. 이러한 시점에서 소방산업을 지식기반형 고부가가치 산업으로 육성시키기 위해서는 산업혁신역량이 요구되며, 산업혁신역량은 인적자원의 경쟁력에 의해 크게 좌우된다. 따라서 본 연구에서는 소방산업 인력을 단순현장기능인력, 고급기술인력, 전문연구인력으로 세 가지로 분류하여 국내 소방산업 인력양성 현황을 살펴보고, 각 분류에 따른 인력양성에 대한 문제점과 개선방안을 제시하고자 한다.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 1994년도 하계학술대회 논문집 C
• /
• pp.1603-1605
• /
• 1994

Recently, Gas Circuit Breakers are rapidly replacing Vacuum Circuit Breakers in the medium voltage switchgear. This is due to the improved performance of - GCB in interrupting capability, price, weight, size etc., while the countermeasure to suppress the switching surges of VCB has not been satisfactory. Intensive research works on the GCB have been conducted in the world widely since 1980. Nowadays it is well known that the thermal expansion type GCB can provide- better performance than puffer type in the distribution power system. KERI has conducted researches in the GCB rated at 25.8kV 25kA with Jinkwang Co. using the thermal expantion principle since 1993. In this paper, the calculated results of electric and magnetic fields for the model GCB are presented and analyzed. The effect of permanent magnet used to improve the interruption capabilty at the low current level is also investigated. The design parameters for the interrupter inspected through the short-circuit tests conducted at high power laboratory of KERI.

• 기술혁신학회지
• /
• 제8권spc1호
• /
• pp.297-322
• /
• 2005

많은 개발도상국들이 경제발전을 위한 전략산업으로 소프트웨어산업을 채택하고 있다. 그리고 오픈 소스 소프트웨어(open source software: OSS)가 소프트웨어 개발을 위한 하나의 대안으로 떠오르면서 OSS를 개발도상국의 소프트웨어 산업 발전을 위한 하나의 전략으로 보는 시각도 등장하고 있다. 이들 개발도상국은 OSS가 소프트웨어산업 발전과 국가경쟁력 강화의 기반으로 인식하고 있다. 소프트웨어산업을 경제발전의 토대로 발전시키기 위해서는 소프트웨어 생산을 위한 기술능력 확보와 강화가 중요하다. OSS는 소프트웨어 개발비용 절감은 물론이고 소프트웨어 기술능력을 증진시키기 위한 기술혁신의 도구로 활용될 수 있다. OSS를 통한 비즈니스 모델은 소프트웨어 판매가 아니라 지원과 서비스이다. 개발도상국들은 OSS 육성정책을 기술인력 양성을 중심으로 추진할 수 있다. 이를 통해 소프트웨어산업 전반의 기술능력을 향상시키고 기술인력을 육성하고 활용할 수 있다. 본 논문은 한국이 OSS를 통해 개발도상국의 소프트웨어산업 발전에 어떻게 기여할 수 있으며, 한국 소프트웨어산업의 해외시장 진출 전략에 어떤 시사점을 주는지 분석할 것이다.

• BMB Reports
• /
• 제51권11호
• /
• pp.572-577
• /
• 2018

Recent studies showed that the PD-1/PD-L1 checkpoint blockade is a dramatic therapy for melanoma by enhancing antitumor immune activity. Currently, major strategies for the PD-1/PD-L1 blockade have mainly focused on the use of antibodies and compounds. Seeking an alternative approach, others employ endogenous proteins as blocking agents. The extracellular domain of PD-1 (ePD1) includes the binding site with PD-L1. Accordingly, we constructed a PD-1-based recombinantly tailored fusion protein (dFv-ePD1) that consists of bivalent variable fragments (dFv) of an MMP-2/9-targeted antibody and ePD1. The melanoma-binding intensity and antitumor activity were also investigated. We found the intense and selective binding capability of the protein dFv-ePD1 to human melanoma specimens was confirmed by a tissue microarray. In addition, dFv-ePD1 significantly suppressed the migration and invasion of mouse melanoma B16-F1 cells, and displayed cytotoxicity to cancer cells in vitro. Notably, dFv-ePD1 significantly inhibited the growth of mouse melanoma B16-F1 tumor cells in mice and in vivo fluorescence imaging showed that dFv-ePD was gradually accumulated into the B16-F1 tumor. Also the B16-F1 tumor fluorescence intensity at the tumor site was stronger than that of dFv. This study indicates that the recombinant protein dFv-ePD1 has an intensive melanoma-binding capability and exerts potent therapeutic efficacy against melanoma. The novel format of the PD-L1-blocked agent may play an active role in antitumor immunotherapy.

• 패션비즈니스
• /
• 제12권5호
• /
• pp.54-66
• /
• 2008

This study aims to suggest better future-oriented improvements by considering the traits and changes of the curriculum of the courses related to the field of fashion. To get the best results from the study, out of all the fashion-related majors (courses) from 4-year based universities in Korea, 65 was selected and divided into 24 courses in the category of clothing & textiles, 34 courses in the category of fashion design and 7 courses in the category of fashion industry in 7 universities, and their education goals and contents of the curriculum posted on the internet homepage of each university were analyzed. The results of the study are as follows: Firstly, with the result from analyzing what the core terms have in common, which are used to express the educational purposes of fashion-related courses in Korea, the ideal type of talents that most of the fashion-related courses tend to pursue can be said to be those who are equipped with a sense of future-oriented creative direction and international communication capability, based on a multidisciplinary general capability, a professional executive ability, an information-analytic ability and an ability of planning, as well as in possession of a sense of beauty, creativity and a scientific mind. Secondly, with the traits of the curriculum of courses in each category, it was found that the category of clothing & textiles courses belongs to colleges of human ecology the most, and in terms of major subjects, the relative importance of clothing science seemed high compared to other school categories while the category of fashion design courses belongs to colleges of art, modeling or design the most, and in terms of major subjects, the scope of dress design appeared the widest, and finally the category of fashion industry courses belongs to colleges of natural science the most, and the relative importance of marketing seemed quite high. Moreover, with the result mentioned earlier, It was found that the names of departments and majors of fashion-related courses are differentiated, depending on what kind of college they belong to, and their curriculum have been differentiated to some degree accordingly. Thirdly, as shown above, Korean universities have attempted to make a lot of changes in the curriculum of fashion-related courses according to changes of the age, compared to what they did in the past, but they have still seemed to lack many things for the cultivation of talents fit for their educational purposes. Through the result from investigating both the changes of the current age and the directions in developing the curriculum, the study came to conclusion that each university in Korea should develop the major curriculum of fashion-related courses that are more sophisticated and intensive fit for the its department name and educational purposes.

• 농업과학연구
• /
• 제43권4호
• /
• pp.537-546
• /
• 2016

The development of models for agriculture systems, especially for crop production, has supported the prediction of crop yields under various environmental change scenarios and the selection of better crop species or cultivar. Crop models could be used as tools for supporting reasonable nutrient management approaches for agricultural land. This paper outlines the simplified structure of main crop models (crop growth model, crop-soil model, and crop-soil-environment model) frequently used in agricultural systems and shows diverse application of their simulated results. Crop growth models such as LINTUL, SUCROS, could provide simulated data for daily growth, potential production, and photosynthesis assimilate partitioning to various organs with different physiological stages, and for evaluating crop nutrient demand. Crop-Soil models (DSSAT, APSIM, WOFOST, QUEFTS) simulate growth, development, and yields of crops; soil processes describing nutrient uptake from root zone; and soil nutrient supply capability, e.g., mineralization/decomposition of soil organic matter. The crop model built for the DSSAT family software has limitations in spatial variability due to its simulation mechanism based on a single homogeneous field unit. To introduce well-performing crop models, the potential applications for crop-soil-environment models such as DSSAT, APSIM, or even a newly designed model, should first be compared. The parameterization of various crops under different cultivation conditions like those of intensive farming systems common in Korea, shortened crop growth period, should be considered as well as various resource inputs.

• Bioinformatics and Biosystems
• /
• 제1권1호
• /
• pp.28-37
• /
• 2006

Recent studies in molecular biology and proteomics have identified a significant number of novel diagnostic, prognostic, and therapeutic disease markers. However, validation of these markers in clinical specimens with traditional histopathological techniques involves low throughput and is time consuming and labor intensive. Tissue microarrays (TMAs) offer a means of combining tens to hundreds of specimens of tissue onto a single slide for simultaneous analysis. This capability is particularly pertinent in the field of cancer for target verification of data obtained from cDNA micro arrays and protein expression profiling of tissues, as well as in epidemiology-based investigations using histochemical/immunohistochemical staining or in situ hybridization. In combination with automated image analysis, TMA technology can be used in the global cellular network analysis of tissues. In particular, this potential has generated much excitement in cardiovascular disease research. The following review discusses recent advances in the construction and application of TMAs and the opportunity for developing novel, highly sensitive diagnostic tools for the early detection of cardiovascular disease.

• 한국전기전자재료학회논문지
• /
• 제27권9호
• /
• pp.561-565
• /
• 2014

Thermoelectric materials have been the topic of intensive research due to their unique dual capability of directly converting heat into electricity or electrical power into cooling or heating. Bismuth telluride ($Bi_2Te_3$) is the best-known commercially used thermoelectric material in the bulk form for cooling and power generation applications In this work we focus on the large scale synthesis of nanostructured undoped bulk nanostructured $Bi_2Te_3$ materials by employing a novel bottom-up solution-based chemical approach. Spark plasma sintering has been employed for compaction and sintering of $Bi_2Te_3$ nanopowders, resulting in relative density of $g{\cdot}cm^{-3}$ while preserving the nanostructure. The average grain size of the final compacts was obtained as 200 nm after sintering. An improved NS bulk undoped $Bi_2Te_3$ is achieved with sintered at $400^{\circ}C$ for 4 min holding time.

• 시스템엔지니어링학술지
• /
• 제9권2호
• /
• pp.23-36
• /
• 2013

Plant industry is one of technology-intensive and most prosperous industries in Korea because of its recent prosperity and promising outlook in export. However, no Korean EPC company has yet been well prepared in lifting their capacity sufficient enough to get the upstream conceptual or basic design and engineering orders for sizable plant projects which are known as the more value-added. If systems engineering, a methodology which developed complex systems such as airplanes and has been justified its effectiveness in Defense and NASA projects, can be integrated with plant engineering which should be developed and applied based on the requirements of so many stakeholders, conditions, lifecycle concepts, and constraints of the projects, huge synergic effect is expected particularly in developing a specific upstream design, which is a conceptual or basic design. The notion of integration with each other between systems engineering and plant engineering can be really the crux of EPC's success in any plant projects. This paper suggests an approach showing a methodology how to dig out, analyze, evaluate, verify and implement the stakeholders' requirements into a plant design in conceptual phase using the theory and skills of systems engineering. ISO/IEC 15288 well known systems engineering standards is used. Carbon capture system is used for a case study, for it is an emerging technology in reducing emissions of carbon dioxide causing global warming from flue gas after combustion. Here systems engineering was proven to play a substantial role in enhancing the capability of designers in developing a conceptual design of whole plant or certain part of crucial plant systems.