• 대한토목학회논문집
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• 제43권6호
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• pp.831-839
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• 2023

본 연구는 재난현장에서 실시간으로 발생하는 정보들을 신속하게 수집·분석하여 정확한 재난현장상황파악과 의사결정을 지원할 수 있는 현장지원시스템의 통합방안을 제안하고, 프로토타입 시뮬레이션을 통해 현장 적용성을 검토하는 것에 그 목적이 있다. 이를 위해 재난현장에서 활용 할 수 있는 정보수집·공유·융합 기술에 대해 검토하였으며, 재난관리 전단계에 필요한 정보자원과 정보의 효율적인 흐름을 만들어낼 수 있는 스마트 재난현장지원시스템의 통합방안에 대해 제시하였다. 이를 기반으로 제작된 프로토타입으로 시스템 운용 가능성을 검토하기 위해 풍수해 재난 시나리오를 토대로 시뮬레이션을 진행하였으며, 시스템 내의 다양한 기능들이 정상적으로 구현되어 GIS 상황판에 표출되는 것을 확인하였다. 본 연구를 통해 급변하는 재난환경 속에서 효율적이고 능동적인 재난대응이 가능해질 것이라 기대된다.

• 한국기술혁신학회:학술대회논문집
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• 한국기술혁신학회 2005년도 추계학술대회
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• pp.675-688
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• 2005

It is essential for any public institution to establish a systematical scheme and a management system to maintain the contents and securities of its ever-expandingweb-site with efficiency. The general users want a reliable system and a simple and stress-free web environment, and expect the public institutions to maintain the accuracy and conformity of information they provide to the public. In かis study, 1 examined a web-site owned by a certain governmental research institute for the current maintenance status and problems to seek an effective and easy-to-use scheme for both users and web managers. Based on what I teamed from my study, 1 moved on to design a web integration system and tested it on the above mentioned web-site for analysis.

• 한국IT서비스학회지
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• 제10권4호
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• pp.67-81
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• 2011

Recently, Mergers and Acquisitions (M&A) have become increasingly popular in the last few decades, and overseas' M&A are particularly increasing to sharpen corporate competitiveness on a global scale. Previous studies showed that one of the main reasons attributes to failures of mergers was the lack of attention to merging information systems. In recent years, both academy and industry have more focused on Post-Merger Integration (PMI) and the integration of information systems (IS) between two companies is one of the critical success factors of corporate. This paper focused on Post-Merger IT (Information Technology) Integration Methodology of Cross-Border M&A. We followed a single-site qualitative case study method in order to investigate the type of phenomenon in M&A's natural setting. Moreover, we examined a typical energy and power company case in order-based industry, so that other industry players may have different results to determine post-merger IT integration method and scope.

• 한국산업융합학회 논문집
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• 제26권6_2호
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• pp.1145-1153
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• 2023

This study presents the development of pointcloud data integration technology in construction sites via drone photogrammetry and MMS LiDAR. The integration of pointcloud data from drones and MMS technology can provide precise and accurate 3D digital maps of construction sites, which can benefit the development of smart construction and BIM. The advantages of using both drones and MMS technology for pointcloud data acquisition in construction sites are discussed, along with the limitations and challenges of using drone photogrammetry and MMS LiDAR for pointcloud data integration. The results of this study can contribute to the advancement of pointcloud data integration technology in construction sites and improve the efficiency and accuracy of construction projects.

• BMB Reports
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• 제45권6호
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• pp.365-370
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• 2012

Hepatitis B virus (HBV) DNA is often integrated into hepatocellular carcinoma (HCC). Although the relationship between HBV integration and HCC development has been widely studied, the role of HBV integration in HCC development is still not completely understood. In the present study, we constructed a pooled BAC library of 9 established cell lines derived from HCC patients with HBV infections. By amplifying viral genes and superpooling of BAC clones, we identified 2 clones harboring integrated HBV DNA. Screening of host-virus junctions by repeated sequencing revealed an HBV DNA integration site on chromosome 11q13 in the SNU-886 cell line. The structure and rearrangement of integrated HBV DNA were extensively analyzed. An inverted duplicated structure, with fusion of at least 2 HBV DNA molecules in opposite orientations, was identified in the region. The gene expression of cancer-related genes increased near the viral integration site in HCC cell line SNU-886.

• Journal of Microbiology and Biotechnology
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• 제25권11호
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• pp.1863-1870
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• 2015

Fibrinolytic enzyme genes (aprE2, aprE176, and aprE179) were introduced into the Bacillus subtilis 168 chromosome without any antibiotic resistance gene. An integration vector, pDG1662, was used to deliver the genes into the amyE site of B. subtilis 168. Integrants, SJ3-5nc, SJ176nc, and SJ179nc, were obtained after two successive homologous recombinations. The integration of each fibrinolytic gene into the middle of the amyE site was confirmed by phenotypes (Amy-, Spec^S) and colony PCR results for these strains. The fibrinolytic activities of the integrants were higher than that of B. subtilis 168 by at least 3.2-fold when grown in LB broth. Cheonggukjang was prepared by inoculating each of B. subtilis 168, SJ3-5nc, SJ176nc, and SJ179nc, and the fibrinolytic activity of cheonggukjang was 4.6 ± 0.7, 10.8 ± 0.9, 7.0 ± 0.6, and 8.0 ± 0.2 (U/g of cheonggukjang), respectively at 72 h. These results showed that construction of B. subtilis strains with enhanced fibrinolytic activities is possible by integration of a strong fibrinolytic gene via a marker-free manner.

• Geomechanics and Engineering
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• 제34권1호
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• pp.29-41
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• 2023

The 3D geospatial modeling of geotechnical information can aid in understanding the geotechnical characteristic values of the continuous subsurface at construction sites. In this study, a geostatistical optimization model for the three-dimensional (3D) mapping of subsurface stratification and the SPT-N value based on a trial-and-error rule was developed and applied to a dam emergency spillway site in South Korea. Geospatial database development for a geotechnical investigation, reconstitution of the target grid volume, and detection of outliers in the borehole dataset were implemented prior to the 3D modeling. For the site-specific subsurface stratification of the engineering geo-layer, we developed an integration method for the borehole and geophysical survey datasets based on the geostatistical optimization procedure of ordinary kriging and sequential Gaussian simulation (SGS) by comparing their cross-validation-based prediction residuals. We also developed an optimization technique based on SGS for estimating the 3D geometry of the SPT-N value. This method involves quantitatively testing the reliability of SGS and selecting the realizations with a high estimation accuracy. Boring tests were performed for validation, and the proposed method yielded more accurate prediction results and reproduced the spatial distribution of geotechnical information more effectively than the conventional geostatistical approach.

• Journal of Positioning, Navigation, and Timing
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• 제10권2호
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• pp.145-151
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• 2021

According to the Korea Augmentation Satellite System (KASS) system milestone, Site Acceptance Test (SAT) has three steps test until the end of the project. SAT#1 is the first time of SAT steps and verify the KASS Reference Station (KRS) and Sub System (S/S) for the monitoring and controllable. After the equipment and software were installed at the Mission Control Center (MCC) with Central Monitoring and Control Simulator (CMS) for the SAT#1, the 1:1 test was progressed when the KRS and S/S are ready to test. SAT#1 has a 10 steps test case and it was progressed each KRS sites. The test was finished throughout the real-time monitoring and the data collection including the data analysis all of the 7 KRS sites. Finally SAT#1 was completed on December 2020 with successfully.

• 한국미생물·생명공학회지
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• 제23권5호
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• pp.536-543
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• 1995

Multicopy integration vector is a very useful vector system in that they can be integrated into chromosomal DNA in several copies and stably maintained under non-selective conditions. To develop a multicopy integration vector system in the yeast Yarrowia lipolytica, P-type ribosomal DNA was cloned from Y lipolytica. A HindIII-BglII fragment of the cloned rDNA and a promoterless URA3 gene were inserted into pGEM1, generating multicopy integration vectors, pMIYL-1 and pMIYL-2. The rDNA fragment is for targeted homologous recombination between the vector and the chromosomal DNA of Y. lipolytica, and the promoterless URA3 gene is a defective selection marker for inducing multicopy integration. pMIYL-1 and pMIYL-2 have an unique restriction enzyme site, KpnI, and two unique restriction enzyme sites, KpnI and EcoRI, repectively, which can be used for targeting of the vectors into the rDNA of Y. lipolytica chromosomal DNA. After transformation of the vectors into Y. lipolytica, copy number and stability were analyzed by Southern hybridization. The vectors were found to be present in less than 5 copies per cell and were stably maintained during growth in non-selective media.

• 대한토목학회논문집
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• 제30권1C호
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• pp.45-51
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• 2010

지하철 터널 시공, 지하공간 시공, 대심도 굴착 등과 같이 도심지에서의 토목구조물 설계와 시공에 있어서 큰 어려움 중의 하나는 도심지 지반조사이다. 여러 가지 지장물, 전기 잡음, 교통 진동 등과 같은 자연적, 인위적 장애물로 인하여 어느 지반조사 기법이든지 그 결과의 신뢰성은 그리 높지 않은 상황이다. 본 연구에서는 이와 같이 현실적 요구가 높은 고품질 도심지 지반조사 기법의 개발을 목표로 하여 선행연구를 수행하였고, 일차적으로 HiRAS(Hybrid Integration of Resistivity and Surface Wave Velocities) 라고 하는 표면파-전기비저항 병합기법을 개발하였다. HiRAS 기법은 표면파 기법인 CapSASW 기법과 전기비저항 기법인 PDC-R 기법을 병합한 것으로서, 지반 매질의 강성 평가에 우수한 CapSASW 기법의 장점과, 전기잡음에 대한 내성과 지층변화 평가에 우수한 특성을 가진 PDC-R 기법의 장점을 동시에 활용하고자 한 것이다. 표면파 기법과 전기비저항 기법을 동시에 활용하는 역산해석의 측면에서는 표면파 기법의 탄성파 속도와 전기비저항 시험의 전기비저항 간의 부지고유관계를 이용하여 병합역산을 수행하는 전략을 채택하였다. 또한 HiRAS 기법 개발과정에서 부차적으로 지반매질의 포아송비 분포를 2차원으로 평가할 수 있는 성과도 도출하였다.