• Journal of the Korea Institute of Building Construction
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• v.23 no.6
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• pp.809-820
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• 2023

In contemporary society, there is a notable rise in single-person households, coupled with an increased demand for residential spaces, necessitating the exploration of suitable housing solutions. Modular architecture is gaining prominence as a method to deliver cost-effective and sustainable living spaces efficiently. This study introduces a method for optimizing the design and construction processes of modular building units through Building Information Modeling(BIM) technology. It involves an analysis of factors that enhance living quality and meet the housing needs of single-person households. Utilizing BIM, a resource-efficient and cost-efficient modular apartment unit has been developed. BIM facilitates the visualization and integration of architectural components, thereby reducing design errors and enhancing productivity. This research evaluates both the benefits and constraints of modular architecture. Modular constructions, when combined with BIM, emerge as a potent solution for housing challenges, enriching the quality and variety of residential options. Nevertheless, considerations such as technical prerequisites and financial implications are also discussed. The study showcases the potential and merits of utilizing BIM for designing apartment units tailored to single-person households, offering a viable approach to ameliorate their living conditions.

• International Journal of Computer Science & Network Security
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• v.24 no.3
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• pp.23-28
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• 2024

The multi-tenancy and high scalability of the cloud have inspired businesses and organizations across various sectors to adopt and deploy cloud computing. Cloud computing provides cost-effective, reliable, and convenient access to pooled resources, including storage, servers, and networking. Cloud service models, SaaS, PaaS, and IaaS, enable organizations, developers, and end users to access resources, develop and deploy applications, and provide access to pooled computing infrastructure. Despite the benefits, cloud service models are vulnerable to multiple security and privacy attacks and threats. The SaaS layer is on top of the PaaS, and the IaaS is the bottom layer of the model. The software is hosted by a platform offered as a service through an infrastructure provided by a cloud computing provider. The Hypertext Transfer Protocol (HTTP) delivers cloud-based apps through a web browser. The stateless nature of HTTP facilitates session hijacking and related attacks. The Open Web Applications Security Project identifies web apps' most critical security risks as SQL injections, cross-site scripting, sensitive data leakage, lack of functional access control, and broken authentication. The systematic literature review reveals that data security, application-level security, and authentication are the primary security threats in the SaaS model. The recommended solutions to enhance security in SaaS include Elliptic-curve cryptography and Identity-based encryption. Integration and security challenges in PaaS and IaaS can be effectively addressed using well-defined APIs, implementing Service Level Agreements (SLAs), and standard syntax for cloud provisioning.

• Journal of Life Science
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• v.25 no.8
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• pp.861-869
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• 2015

One of the domesticated species; the dog has been selectively bred for various aims by human. The dog has many breeds, which are artificially selected for specific behaviors and morphologies. Dogs contribute their life to human as working dogs for guide, rescue, detection or etc. Working dogs requires good personality, such as gentleness, robustness and patience for performing their special duty. Many studies have concentrated on finding genetic marker for selecting the high-quality working dog. In this study, we confirmed quantitative expression patterns of eight genes (ABAT; 4-Aminobutyrate Aminotransferase, PLCB1; Phospholipase C, Beta 1, SLC10A4; Solute Carrier Family 10, Member 4, WNT1; Wingless-Type MMTV Integration Site Family, Member 1, BARX2; BarH-Like Homeobox 2, NEUROD6; Neuronal Differentiation 6, SEPT9; Septin 9 and TBR1; T-Box, Brain, 1) among brains tissues from four dog breeds (Beagle, Sapsaree, Shepherd and Jindo), because these genes were expressed and have functions in brain mostly. Specially, BARX2, SEPT9, SLC10A4, TBR1 and WNT1 genes were highly expressed in Beagle and Jindo, and Sapsaree and German Shepherd were vice versa. The biological significance of total genes was estimated by database for annotation, visualization and integrated discovery (DAVID) to determine a different gene ontology (GO) class. In these analyses, we suppose to these eight genes could provide influential information for brain development, and intelligence of organisms. Taken together, these results could provide clues to discover biomarker related to functional traits in brain, and beneficial for selecting superior working dogs.

• Clinical and Experimental Reproductive Medicine
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• v.37 no.3
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• pp.207-216
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• 2010

Objective: This study was performed to clarify the role of HomeoboxA (HOXA) and its related signaling molecules in the decidualization of primary cultured endometrial cells. Methods: Human endometrial tissues were obtained by curettage of hysterectomy specimens from patients with conditions other than endometrial diseases. Tissues were minced and digested with Trypsin-EDTA for 20 min, $37^{\circ}C$. Cells were cultured with DMEM/F12 medium in $37^{\circ}C$, 5% $CO_2$ incubator for 24 hrs. Cells were treated with HOXA10 siRNA and added transforming growth factor (TGF)-${\beta}1$ (10 ng/mL) for 48 hrs to induces decidualization in vitro. Reverse transcription polymerase chain reaction analysis was accomplished to observe the expression of HOXA10, prolactin, cyclooxygenase (COX)-2, peroxisome proliferatoractivated receptor (PPAR)-$\gamma$, and wingless-type MMTV integration site family (Wnt). Results: HOXA10 expression was increased (1.8 fold vs. non-treated control) in TGF-${\beta}1$ treated cells. Decidualization marker, prolactin, was significantly increased in TGF-${\beta}1$ treated cells compared with HOXA10 siRNA treated cells. Endometrial cell differentiation marker, COX-2 was down-regulated by HOXA10 siRNA even if cells were treated with TGF-${\beta}1$. Wnt4 was down-regulated by treated with HOXA10 siRNA, this expression patters was not changed by TGF-${\beta}1$. Expression of PPAR-$\gamma$ was down regulated by TGF-${\beta}1$ in regardless of HOXA10 siRNA treatment. Conclusion: TGF-${\beta}1$ which is induced by progesterone in endometrial epithelial cells may induces stromal cell decidualization via HOXA10 and Wnt signaling cascade.

• Tunnel and Underground Space
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• v.33 no.4
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• pp.281-298
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• 2023

Continuous research efforts are being devoted to unmanned mobile platforms for lunar exploration. There is an ongoing demand for real-time information processing to accurately determine the positioning and mapping of areas of interest on the lunar surface. To apply deep learning processing and analysis techniques to practical rovers, research on software integration and optimization is imperative. In this study, a foundational investigation has been conducted on real-time analysis of virtual lunar base construction site images, aimed at automatically quantifying spatial information of key objects. This study involved transitioning from an existing region-based object recognition algorithm to a boundary box-based algorithm, thus enhancing object recognition accuracy and inference speed. To facilitate extensive data-based object matching training, the Batch Hard Triplet Mining technique was introduced, and research was conducted to optimize both training and inference processes. Furthermore, an improved software system for object recognition and identical object matching was integrated, accompanied by the development of visualization software for the automatic matching of identical objects within input images. Leveraging satellite simulative captured video data for training objects and moving object-captured video data for inference, training and inference for identical object matching were successfully executed. The outcomes of this research suggest the feasibility of implementing 3D spatial information based on continuous-capture video data of mobile platforms and utilizing it for positioning objects within regions of interest. As a result, these findings are expected to contribute to the integration of an automated on-site system for video-based construction monitoring and control of significant target objects within future lunar base construction sites.

• Research in Plant Disease
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• v.19 no.4
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• pp.254-258
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• 2013

Fusaric acid (FA) is a mycotoxin produced by Fusarium species. Its toxicity is relatively low but often associated with other mycotoxins, thus enhancing total toxicity. To date, biosynthetic genes or enzymes for FA have not been identified in F. oxysporum. In order to explore the genetic element(s) for FA biosynthesis, restriction enzyme mediated integration (REMI) procedure as an insertional mutagenesis was employed using FA producing-F. oxysporum strains. Genetic transformation of two F. oxysporum strains by REMI yielded more than 7,100 transformants with efficiency of average 3.2 transformants/${\mu}g$ DNA. To develop a screening system using phytotoxicity of FA, eleven various grains and vegetable seeds were tested for germination in cultures containing FA: Kimchi cabbage seed was selected as the most sensitive host. Screening for FA non-producer of F. oxysporum was done by growing each fungal REMI transformant in Czapek-Dox broth for 3 weeks at $25^{\circ}C$ then observing if the Kimchi cabbage seeds germinated in the culture filtrate. Of more than 5,000 REMI transformants screened, fifty-three made the seeds germinated, indicating that they produced little or fewer FA. Among them, twenty-six were analyzed for FA production by HPLC and two turned out to produce less than 1% of FA produced by a wild type strain. Sequencing of genomic DNA regions (252 bp) flanking the vector insertion site revealed an uncharacterized genomic region homologous (93%) to the F. fujikuroi genome. Further study is necessary to determine if the vector insertion sites in FA-deficient mutants are associated with FA production.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.34 no.2
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• pp.180-186
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• 2008

Purpose: This study was performed to evaluate the effect of the implant recipient site preparation methods on primary stability of implants with the instruments of $Osstell^{TM}$ and $Periotest^{(R)}$ in the iliac bone of cadaver. Methods and materials: The 8 iliac bones in 4 cadavers and implants treated with resorbable blasting media (RBM) were used. $Periotest^{(R)}$ (Simens AG, Germany) and $Osstell^{TM}$ (Model 6 Resonance Frequency Analyser: Integration Diagnostics Ltd., Sweden) were used to measure primary stability of implants. Implants were inserted into the iliac crest of the cadaver. In control group, the recipient site was prepared according to the manufacturer's recommendation: 1.8 mm guide drill, 2.0 mm initial drill, 2.7 mm pilot drill, 2.7 mm twist drill, 3.0 mm twist drill, 3.3 mm pilot drill, 3.3 mm twist drill, and 3.3 mm countersink drill as well as tapping drill were used in order. In the group 1, implant recipient sites were prepared by sequentially drilling from 1.8 mm guide drill to 3.0 mm twist drill and then inserted implants without countersinking and tapping. In the group 2, implant recipient sites were prepared to 3.0 mm twist drill and countersink drill and then inserted implants without tapping. In the group 3, the sites were prepared to 3.0 mm twist drill and countersink drill as well as tapping drill. In the group 4, the sites were prepared to 3.3 mm twist drill. In the group 5, the sites were prepared to 3.3 mm twist drill and countersink drill. A total of 60 implants were placed (n=10). The stability was measured using $Osstell^{TM}$ and $Periotest^{(R)}$ mesiodistally and buccolingually. To compare the mean stability of each group statistically, One-way ANOVA was used and correlation of instrument were analyzed using SPSS 12.0. The results obtained were as follows; 1. The stability of group 1 measured using $Osstell^{TM}$ and $Periotest^{(R)}$ buccolingually showed the highest, and there are significant difference statistically between control group and experimental group 1,2,4 in each instruments respectively (p<0.05). 2. The stability of group 1 measured using $Osstell^{TM}$ and $Periotest^{(R)}$ mesiodistally showed the highest. There are significant difference statistically between control group and all experimental groups in $Osstell^{TM}$, and between control group and experimental group 1,2,3,4 (p<0.05). 3. There are high correlation between the measurements of $Osstell^{TM}$ and $Periotest^{(R)}$ (p<0.05). Conclusion: These results indicate that the primary stability of implant can be obtained by the recipient sites preparation with smaller diameter drill than that of implant or minimal drilling.

• Journal of Plant Biotechnology
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• v.38 no.1
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• pp.15-21
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• 2011

We developed 14 transgenic lines of Chinese cabbage (Brassica rapa) harboring the T-DNA border sequences and CryIAc1 transgene of the binary vector 416 using Agrobacterium tumefaciens-mediated DNA transfer. Six lines had single copy cryIAc1 gene and four of them contained no vector backbone DNA. Of the left border (LB) flanking sequences six nucleotides were deleted in transgenic lines 416-2 and 416-3, eleven nucleotides in line 416-9, and 65 nucleotides including the whole LB sequences in line 416-17, respectively. And we defined 499 bp of genomic DNA (gDNA) of transformed Chinese cabbage, and blast results showed 96% homology with Brassica oleracea sequences. PCR with specific primer for the right border (RB) franking sequence revealed 834 bp of PCR product sequence, and it was consisted of 3' end of cryIAc1, nosterminal region and 52 bp of Chinese cabbage genomic DNA near RB. RB sequences were not found and the 58 nucleotides including 21 bp of nos-terminator 3' end were deleted. Also, there were deletion of 10 bp of the known genomic sequences and insertion of 65 bp undefined genomic sequences of Chinese cabbage in the integration site. These results demonstrate that the integration of T-DNA can be accompanied by unusual deletions and insertions both in transgenic and genomic sequences.

• Journal of the Korean Institute of Landscape Architecture
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• v.39 no.1
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• pp.96-105
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• 2011

This study analyzed literary works and references related to Dok-Rak-Dang(獨樂堂) and the attributes of managing the landscape in Dok-Rak-Dang Garden based on the assumption of position and the spatial structure revealed in the site. Hoe-Jae Lee Eon-Jeok(1491-1553), a distinguished scholar of Neo-Confusionism, built Dok-Rak-Dang and managed the surrounding areas during his retirement years. He called the mountains, stream, and rock along and near the Ja-Ge Stream Four Mountains and Five Platforms(四山五臺). Before he named these, they were not considered special. The Four Mountains which are Do-Duk in north, Mu-Hak in south, Hwa-Gae in east, and Ja-Ok in west enclose Dok-Rak-Dang and the surrounding areas. The Five Platforms, Se-Sim, Gwan-Eo, Yeong-Gue, Jing-Sim, and Tak-Yeong, in order from downstream, are places with beautiful scenery in Ja-Ge Stream. The attributes of managing the landscape in Dok-Rak-Dang Garden are the following: One is the spatial integration of what is natural and artificial as the attitude of aesthetic experience in accord with nature. Another is flexible territorialization as the way of organizing spaces in nature from the experiential aspect. The other is place making of personalized nature through a series of processes such as observing, choosing, and naming landscapes in nature. Four Mountains and Five Platforms function as landscape bases and elements to appreciate nature aesthetically. Those attributes are different from the attitude of constructing spaces. Rather, they originate from the traditional view on the appreciation of nature. Above all, place-making in nature was acquired from designed spatial structure and experiential aesthetic appreciation in the space through observing, choosing, and naming landscapes in nature reflecting creator's own ideological and aesthetic thoughts, and it might be explained as one of practical ways of Korean traditional gardening.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.10
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• pp.4523-4535
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• 2012

As a way to popularize Karatedo, a curriculum for developing excellent trainers is needed. For that, DACUM was used to specifically look into the field of duty and work that a Karatedo trainer should have, and the purpose of this study is to present fundamental data necessary for developing and organizing the curriculum of cultivating Karatedo and create a useful material that can contribute to improve Karatedo trainers' performances who are working on site. A survey using Likert scale's 7 stages was conducted on DACUM meeting data, 28 managers and 108 trainers. Based on the collected data, this study had a test in order to solve the presented subject using DACUM method and SPSS WIN Ver. 14.0. This core work through the requirements analysis process. And karate leaders the necessary knowledge, skills, and tools, and attitude analysis was carried out to perform the tasks of each. Knowledge, skills, tools and attitude for each task, toward the results of the analysis were 47 core tasks. 167 knowledge items, function 143 items, the tool 60 items, 16 attitude items reclassified a total of 18 subjects were derived. The configuration of the karate leader training program curriculum model 'Karate practical expert area', 'theory karate expert area', 'Karate gym business area experts' was composed. Basic process of how it works Step 1, Step 2 integration process, replenishment process intensified Step 3 was composed.