• Korean Journal of Plant Resources
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• v.23 no.4
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• pp.360-367
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• 2010

The genetic diversity and structure of P. tongkangensis in 5 populations from 3 regions was investigated using 56 markers derived from 6 ISSR primers. Genetic diversity at the species level (P=94.6, SI=0.377, h=0.240) was substantial considering the limited distribution and small size of populations. Genetic differentiation among regions (12%) and among populations (13%) in the region was not clearly evident, which suggested a moderate level of gene flow among adjacent populations. The Mantel test revealed a significant correlation between genetic differentiation (${\Phi}_{ST}$) and geographic distance among populations. This was supported by cluster analysis and principal coordinate analysis (PCoA). The significant difference in marker band frequency at many loci and their fixation in opposite directions in the smallest and most isolated population SC were considered due to genetic drift. Therefore, the genetic diversity of P. tongkangensis could be compromised if the distribution area or the size of the population was further reduced. In particular, small and isolated populations could be at great risk of extinction. Considering this, the unique habitats of P. tongkangensis should be protected and the reduction of population size should be closely monitored. Conservation efforts including the seeding and planting of seedlings should be done carefully based on their genetic and ecological traits. Our data support the argument that establishing an integrated management system for the efficient conservation of P. tongkangensis is critical.

• Journal of Gastric Cancer
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• v.17 no.2
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• pp.132-144
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• 2017

Purpose: To identify baseline prognostic factors for survival in patients with disease progression, during or after chemotherapy for the treatment of advanced gastric or gastroesophageal junction (GEJ) cancer. Materials and Methods: We pooled data from patients randomized between 2009 and 2012 in 2 phase III, global double-blind studies of ramucirumab for the treatment of advanced gastric or GEJ adenocarcinoma following disease progression on first-line platinum- and/or fluoropyrimidine-containing therapy (REGARD and RAINBOW). Forty-one key baseline clinical and laboratory factors common in both studies were examined. Model building started with covariate screening using univariate Cox models (significance level=0.05). A stepwise multivariable Cox model identified the final prognostic factors (entry+exit significance level=0.01). Cox models were stratified by treatment and geographic region. The process was repeated to identify baseline prognostic quality of life (QoL) parameters. Results: Of 1,020 randomized patients, 953 (93%) patients without any missing covariates were included in the analysis. We identified 12 independent prognostic factors of poor survival: 1) peritoneal metastases; 2) Eastern Cooperative Oncology Group (ECOG) performance score 1; 3) the presence of a primary tumor; 4) time to progression since prior therapy <6 months; 5) poor/unknown tumor differentiation; abnormally low blood levels of 6) albumin, 7) sodium, and/or 8) lymphocytes; and abnormally high blood levels of 9) neutrophils, 10) aspartate aminotransferase (AST), 11) alkaline phosphatase (ALP), and/or 12) lactate dehydrogenase (LDH). Factors were used to devise a 4-tier prognostic index (median overall survival [OS] by risk [months]: high=3.4, moderate=6.4, medium=9.9, and low=14.5; Harrell's C-index=0.66; 95% confidence interval [CI], 0.64-0.68). Addition of QoL to the model identified patient-reported appetite loss as an independent prognostic factor. Conclusions: The identified prognostic factors and the reported prognostic index may help clinical decision-making, patient stratification, and planning of future clinical studies.

• Journal of Korea Entertainment Industry Association
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• v.13 no.1
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• pp.25-34
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• 2019

The purpose of this study is to develop a mobile app for mental health self care of university student. User centered design is a research design that applies the subject's needs assessment, analysis, design, development, evaluation, modification and supplement to suit the subjects. In order to manage the mental health of university students, they consisted of four main areas of mental health problems: drinking, sleeping, depression, and stress. It is designed to enable self test content, analysis and notification of inspection results, and management plan for current status of each area. Based on this, I developed an Android based mental health self-care Application. The subject can enter his or her mental health status data to explain the normal or risk level for each result, and the subject can then select the appropriate intervention method that he or she can perform. In addition, we developed a mental health self care calendar that can display the present status of each of the four areas on a day by day basis, and the current status can be expressed in an integrated manner through animations and status bars. The purpose of this study was to develop a mental health self-care app that can be improved by continuous and improved programs.

• Journal of the Korean Institute of Gas
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• v.28 no.1
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• pp.19-26
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• 2024

In workplaces handling flammable gas such as hydrogen, hazardous area is determined through KS C IEC 60079-10-1 standard. Because this standard determines the hazardous distance based on the release characteristic regardless of the type of gas, indoor/outdoor conditions, and atmospheric conditions, concerns are being raised about the effectiveness. In this study, simulations (PHAST, HyRAM) were performed to calculate the hazardous distance for hydrogen under various release characteristics and atmospheric conditions, and compared these results to IEC standard log-log graph. Also, we performed regression analysis according to each result. we found that the simulation results were 0.6 to 3.8 times less than the IEC standard, presented convenient linear regression equations. In addition, We confirmed that the results of hazardous distance varied based on wind velocity and atmospheric stability at the same release characteristic. In addition, we derived linear regression equations for release characteristics and hazardous distance that can be conveniently utilized. So, when classifying hazardous area in workplaces where they handle the hydrogen, the integrated graph and linear regression equation are helpful for confirming the hazardous area. Moreover, it is expected that the economic burden will be minimized by being able to classify reasonable hazardous area and to greatly reduce the risk of hydrogen explosion.

• Journal of the Korean Association of Geographic Information Studies
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• v.27 no.3
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• pp.60-75
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• 2024

Research on health outcomes of environmental factors has been implemented by multiple and interacting factors, including environmental, socio-demographic, economic, and traffic aspects. There are still significant challenges and limitations in constructing databases for the connections between contributing factors and an integrated approach to environmental health research even though there has been a dramatic increase in data availability and incredible technological advance in data storage and processing. This study emphasizes the necessity of establishing a geospatial data pipeline to analyze the impact of environmental factors on health. It also highlights the difficulties and solutions related to the construction and utilization of a geospatial database. Key challenges include diverse data sources and formats, different spatio-temporal data structures, and coordinate system inconsistencies over time within the same geospatial data. To address these issues, a data pipeline was constructed with pre-processing and post-processing for the data, resulting in refined datasets that could be used for calculating geographic variables. In addition, an AWS-based relational database and shared platform were established to provide an efficient environment for data storage and analysis. Guidelines for each step of the process, including data management and analysis, were developed to enable future researchers to effectively use the data pipeline.

• Korean Chemical Engineering Research
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• v.51 no.2
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• pp.221-225
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• 2013

Sustainability, in general, means the protection of environmental resources and economic prosperity, with the consideration of the social, economic and environmental effect, as well as human health and the enhancement of life. Profound consideration about sustainability has to handle the overall cycle of feedstock, resource extraction, transportation and production in addition to the environmental effect. Sustainable development of the chemical industries should be carried out complementarily by strengthening the chemical process safety of the industries. In this respect, chemical process safety can be called an opportunity to enhance the compatibility internationally. Changing new paradigm in chemical process safety is formed from the overall life cycle considering basic design of existing systems and production processes. To improve the chemical process safety, the integrated smart system is necessary, comprising various chemical safety database and knowledge base and improved methods of quantitative risk analysis, including management system. This paper discussed the necessity of overall life cycle in chemical process safety and proposed new technology to improve the sustainability. To develop the sustainable industries in process systems engineering, three S, which include Safety, Stability and Security, will have to be combined appropriate.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.8 no.1
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• pp.223-233
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• 2013

The purpose of this study is to analyze the factors giving effects to juvenile's suicide thinking and search for the method to protect juveniles from the risk factors of suicide thinking and reinforce protective factors. For this purpose, juvenile's depression and stress degree were analyzed as the factors giving effects to juvenile's suicide thinking and the effect of social support, which was assumed as a protective factor from suicide thinking, was verified. Analysis results are as follows. First, juvenile's daily stress showed significant deference from suicide thinking. There was a significant positive correlation between juvenile's daily life stress and suicide thinking. Therefore, it was found that the juveniles who suffer from stress have a lot of suicide thinking. Second, juvenile's depression gave a significant effect to suicide thinking. There was a significant positive correlation between juvenile's depression and suicide thinking. it was proved that the juveniles who suffer from depression have a lot of suicide thinking. Third, There was a significant negative correlation between social support and suicide thinking. The more the juveniles get social support, the less they have suicide thinking. The study results above reveal that juvenile's suicide shall be approached from the preventive aspect, for preventing juvenile's suicide, social support which mitigates suicide thinking factors is very important. Therefore this study proposed social attention on the juvenile's suicide thinking, and formation social support system that reinforce social support. Moreover, for preventing the factors reinforcing suicide thinking, preventive approach, alternative program such as case management and group program, and integrated management inined with juvenile related organizations and specialists are required. At the same time school environment shall be improved and changed.

• Journal of Satellite, Information and Communications
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• v.3 no.1
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• pp.41-47
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• 2008

Line-of-sight communications cannot easily support korean armed forces because of mountainous terrain. ADD(Agency for Defense Development) introduced ANASIS(Army Navy Air-force Satellite Information System) to meet the Korean warfighter's operational needs. Currently, army's military satcom terminal is designed for either fixed site or on-the-pause operation. The US army is under development of multi-band integrated on-the-move satellite terminals to let the army's communication capability to keep pace with globally deployable Joint Task Force for network-centric application. In this paper we analyzed X-band and Ka-band link and subsystem requirement. Our focus here is to describe key technical issues. Especially, On the basis of 3dB beam width of 0.9m antenna, Tracking accuracy and disturbances compensation signal processing on-the-move of Antenna Tracking system is analyzed. Also, protocol is analyzed that minimize blockage on the move due to an obstacle. when the received signal blocked, it stop to transmit burst signal and retransmit when blockage removed through received synchronization signal monitoring. Analyzed specification will be used to make prototype terminal to analyze risk for mass production

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.8
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• pp.147-153
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• 2020

Developments in aircraft require safety verification through flight testing for many hours with prototype design and production. The test evaluation step of performing flight tests was an important process that determines the success in the development of the system. In particular, safety development through flight tests in the armed flight test is important for the development of attack helicopters. In the development of attack helicopters, the evaluation period and cost related to the armed flight test are closely related to the required ammunition requirement. Therefore, this paper presents the amount of ammunition required for the military flight test between attack helicopter developments through an analysis of the AH-1 helicopter in a similar case and ADS-44-HDBK of military specification. The AH-1 can be used to calculate the ammunition demand by considering the exclusion of redundant firing tests and configuration differences. In the case of the machine gun-equipped configuration, approximately 10,500R was required, and approximately 324R was required in the case of a rocket-mounted configuration. In addition, if the armed integrated bench is used properly, it is expected to promote efficiently the flight test in the armed flight by identifying the possible risk factors with armed flight tests and excluding them.

• Journal of Global Scholars of Marketing Science
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• v.16 no.3
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• pp.169-189
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• 2006

The product categories that can be sold on-line are expanding. It is interesting to see which product categories have more sales possibilities on internet. Small-sized firms' products have low distribution coverage, low brand recognition, bigger dispersion in the perception on the values which consist of quality vs. price, and higher possibilities of perceived purchase risks. Since on-line shopping is supposed to provide opportunities to small-sized firms that have low distribution and brand power, it is quite necessary to evaluate the fitness of on-line sales for small-sized firms' product categories. There are virtually no research studies on the on-line sales for small-sized firms' product categories. In this study, based on the integration of SEC, FCB, and related concepts, we develop new theoretical framework and test the fitness of on-line sales for small-sized firms' product categories by conducting empirical analysis. The empirical results on 17 product categories show that SEC, FCB, purchase risks, brand factors are somewhat related. Unlike previous studies, since the fitness of SEC and on-line sales are not clearly shown, we need to consider those problems within inter-related multiple frameworks. That is, it is necessary to evaluate the fitness of on-line sales after defining the product categories within the integrated multiple frameworks rather than within the single framework.