• Journal of the Korean Association of Geographic Information Studies
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• v.21 no.3
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• pp.149-161
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• 2018

As a result of analyzing the relationship between the smart growth principle and the regenerating factors of the port waterfront city, it was found to be highly related to the port waterfront regeneration plan. Factors that are related to the application of smart growth principle derived from association analysis are as follows: ⯈ community development suitable for walking ⯈ differentiated and attractive community building with definite place, ⯈ open space, farmland, beautiful natural scenery, environmental preservation, ⯈ strengthening and inducing development for existing communities, and providing diversity of transportation options. However, in the Jeju port redevelopment plan, the principles such as ⯈ complex land use ⯈ advantage of high-density architectural design method, ⯈ various housing opportunities and options, etc., need to be applied in implementation design. Since Jeju city and Jeju port possess the strong characteristic features of port waterfront city, so it is necessary to develop jointly applying smart growth principle through integrated port waterfront city regeneration plan.

• Journal of Periodontal and Implant Science
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• v.44 no.5
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• pp.251-258
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• 2014

Purpose: The preferred material for bone augmentation beyond the envelope of skeletal bone is the bone block graft, due to its dimensional stability. We evaluated the necessity of rigid fixation for the bone block graft, and compared the bone regeneration and volume maintenance associated with grafting using a synthetic hydroxyapatite block (HAB) and an autogenous bone block (ABB) without rigid fixation on rabbit calvaria over two different periods. Methods: Cylinder-shaped synthetic HAB and ABB were positioned without fixation on the rabbit calvarium (n=16). The animals were sacrificed at 4 or 8 weeks postoperatively, and the grafted materials were analyzed at each healing period using microcomputed tomography and histologic evaluation. Results: Integration of the graft and the recipient bed was observed in all specimens, although minor dislocation of the graft materials from the original position was evident in some specimens (six ABB and ten HAB samples). A tendency toward progressive bone resorption was observed in the grafted ABB but not in the grafted HAB, which maintained an intact appearance. In the HAB group, the area of new bone increased between 4 and 8 weeks postoperatively, but the difference was not statistically significant. Conclusions: The nonfixed HAB was successfully integrated into the recipient bed after both healing periods in the rabbit calvaria. In spite of limited bone formation activity in comparison to ABB, HAB may be a favorable substitute osteoconductive bone material.

• Animal cells and systems
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• v.2 no.1
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• pp.1-8
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• 1998

Hepatocyte growth factor (HGF), originally discovered and cloned as a powerful mitogen for hepatocytes, is a four kringle-containing growth factor which specifically binds to membrane-spanning tyrosine kinase, c-Met/HGF receptor. HGF has mitogenic, motogenic (enhancement of cell movement), morphogenic (e.g., induction of branching tubulogenesis), and anti-apoptotic activities for a wide variety of cells. During embryogenesis, HGF supports organogenesis and morphogenesis of various tissues, including liver, kidney, lung, gut, mammary gland, and tooth. In adult tissues HGF elicits an organotrophic function which supports regeneration of organs such as liver, kidney, lung, and vascular tissues. HGF is also a novel member of neurotrophic factor in nervous systems. Together with the preferential expression of HGF in mesenchymal or stromal cells, and c-Met/HGF receptor In epithelial or endothelial cells, the HGF-Met coupling seems to orchestrate dynamic morphogenic processes through epithelial-mesenchymal (or-stromal) interactions for organogenesis and organ regeneration. HGF or HGF gene may well become unique therapeutic tools for treatment of patients with various organ failure, through its actions to reconstruct organized tissue architectures. This review focuses on recently characterized biological and physiological functions integrated by HGF-Met coupling during organogenesis and organ regeneration.

• Journal of the Korean housing association
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• v.27 no.3
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• pp.47-58
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• 2016

The new paradigm of urban regeneration, would promote the comprehensive communal view. Therefore, the community role has become an important and necessary for regeneration of communities. It is necessary for urban regeneration which should be matched with the regional characteristics, to develop an evaluation framework that can objectively and accurately diagnose the status of community; so it can be an integrated prescription. A new alternative, asset-based approach may be an alternative to build the community based on opportunities and strengths, which focuses on community inside and things that community have. In this study, a community asset is defined as the tangible and intangible components in the community. A community asset evaluation system is developed through the content analysis related to previous studies of several researchers who investigated the asset-based approaches. Community assets are classified into seven types: human, social, cultural, natural, physical, economic, and political property. Each type is classified into components and establish as a framework with 3 levels in order to set the indicators which can be measured concretely.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.34 no.1
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• pp.23-32
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• 2018

This study starts from the architectural and urban interest to integrate the daily life and behavior of residents in the city of Seongnam and to sustain the community. A fixed abode is something that can not be separated from the place and should be approached from a comprehensive perspective reflecting the physical and social conditions of the region. Although residential neighborhoods have a residential walking range, which has a steep slope, it has been formed in the suburbs of the residential area where commercial facilities are activated organically. The humanities and social organizations of the residents are integrated with the physical space and act as constituent factors of major cities. This is an attempt to suggest improvement and activation of existing cities based on their daily lives, rather than destroying cities and creating new ones. Also, it is proposed to 'Neighborhood Street' as an indicator of a uniform urban renewal plan for existing urban regeneration projects. Based on the definition of the city of living in the city, the center of the city will be located in the center of the city, and it will be the center of the city's bustling streets.

• Journal of Korea Planning Association
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• v.54 no.1
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• pp.108-117
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• 2019

The purpose of this study is to investigate whether the plan reflecting the place in cultural regeneration was implemented and whether it was a change of place in culture through culture analyze. Mullae-dong has changed its urban structure into a textile factory, a manufacturing industry, an ironworks+artistic complex, and the Mullae art factory has been organizing a festival that has been created by artists and residents alike in the Mullae creative village. However, prior to the creation of the Mullae art factory in the social element, self-sustaining programs of Mullae creative villages were derived, but now commercial space is mainly derived. Therefore, it is necessary to plan for coexistence of ironworks, cultural space and commercial space rather than expanding into commercial space. Geumcheon-gu Geumcheon-gu Geumcheon Art Factory has become an integrated complex where various industries coexist in industrial complex. Geumcheon Art Factory also holds an artist support program every year and actively works as an international creative exchange center in Seoul. However, programs that act as a mediator are not implemented since 2014, and the Open Studio stops once a year. Therefore, Geumcheon-gu needs to expand programs that can include local programs and programs that can be combined with local cultural media.

• Membrane and Water Treatment
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• v.4 no.4
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• pp.237-249
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• 2013

Ultra-pure water (UPW), a highly treated water free of colloidal material and of a conductivity less than 0.06 ${\mu}S$, is an essential component required by modern industry. One of the methods for UPW production is the electrodialysis-ion exchange (ED/IE) system, in which the electrodialysis (ED) process is used as a preliminary demineralization step. The IE step can be replaced with electrodeionization (EDI) to decrease the volume of post-regeneration lyes. In this paper, the electrodialysis process carried out to relatively low diluate conductivity was investigated and the costs of UPW production were calculated. The optimal value of desalination degree by ED in the ED/IE and ED/EDI systems was estimated. UPW unit costs for integrated ED/IE and ED/EDI systems were compared to simple ion exchange and other methods for UPW production (RO-IE, RO-EDI). The minimal UPW unit costs in ED/EDI integrated system were estimated as $0.37/$m^3$ for feed TDS 600 mg/L and $0.36/$m^3$ for feed TDS 400 mg/L at 64 $m^3/h$ capacity, which was lower than in the comparable ED/IE integrated system ($0.42-0.44/$m^3$). The presented results suggest that an ED/EDI integrated system may be economically viable.

• Journal of Power Electronics
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• v.11 no.4
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• pp.527-532
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• 2011

Due to the need for improved fuel consumption and the trend towards increasing the electrical content in automobiles, integrated starter generator (ISG) systems are being considered by the automotive industry. In this paper, in order to change the conventional generator of a vehicle, a belt driven integrated starter generator is considered. The overall ISG system, the design considerations for the claw pole type AC electric machine and a low voltage very high current power stage implementation are discussed. Test data on the low voltage claw pole type machine is presented, and a large current voltage source DC/AC inverter suitable for low voltage integrated starter generator operation is also presented. A metal based PCB (Printed Circuit Board) power unit to attach the 4-parallel MOS-FETs is used to achieve extremely high current capability. Furthermore, issues related to the torque assistance during vehicle acceleration and the generation/regeneration characteristics are discussed. A prototype with the capability of up to 1000 A and 27 V is designed and built to validate the kilo-amp inverter.

• Korean Journal of Construction Engineering and Management
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• v.10 no.1
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• pp.69-77
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• 2009

Recently, a research of the urban regeneration has been performed very actively. This is one of the efforts to resolve various social and economic problems coming from the existing deteriorated building and facilities by new urban development or redevelopment. However, an urban regeneration has a characteristic to be unable to ensure the project performance due to the exposed numerous risks coming from the various and complex stake-holders, and its mega sizes. This paper proposes the method of risk performance index in order to improve an efficiency of performance measurement expanding to the risk view point from the existing integrated cost/schedule performance measurement. A risk performance index is compatible with the existing EVMS, and can make the performance measurement in 3 dimensions of the integrated cost/schedule/risk with 18 sub-indexes and variables.

• BMB Reports
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• v.48 no.4
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• pp.193-199
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• 2015

Degenerative retinal diseases affect millions of people worldwide, which can lead to the loss of vision. However, therapeutic approaches that can reverse this process are limited. Recent efforts have allowed the possibility of the stem cell-based regeneration of retinal cells and repair of injured retinal tissues. Although the direct differentiation of pluripotent stem cells into terminally differentiated photoreceptor cells comprises one approach, a series of studies revealed the intrinsic regenerative potential of the retina using endogenous retinal stem cells. Muller glial cells, ciliary pigment epithelial cells, and retinal pigment epithelial cells are candidates for such retinal stem cells that can differentiate into multiple types of retinal cells and be integrated into injured or developing retina. In this review, we explore our current understanding of the cellular identity of these candidate retinal stem cells and their therapeutic potential for cell therapy against degenerative retinal diseases. [BMB Reports 2015; 48(4): 193-199]