• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.6
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• pp.4284-4290
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• 2015

Recently, due to a decline in traditional industrial function and recession of the real estate business, urban coastal settlement areas have been promoted in a regeneration way using historical cultural values rather than overall development approach. This study investigated the regional assets of water-front area around Yeongdodaegyo Bridge in Yeongdo-gu, Busan and classified them into physical social economic assets and then, presented the integrated regeneration approach that can increase the place value of this area. First, physical regeneration proposed a regional revitalization plan by considering place and cultural characteristics and second, social regeneration by considering the regional brand through storytelling and third, economic regeneration by considering historical cultural characteristics. Regional assets-based culture experience can be provided by building cultural tourism infrastructure through this and local economy and local community activation can be expected by providing urban vitality base of coastal settlement areas.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.35 no.9
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• pp.29-40
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• 2019

The concept of smart city is understood as an indispensable component of urban regeneration projects in small cities in terms of providing a better urban environment and efficient living systems with a limited budget. Recently, the Korean government revised the law that related to the construction of the smart city and started to implement the smart city concept not only to new-large urban development but also to small-existed regeneration projects. However, it is difficult for small and medium-sized cities that are suffering from the insufficient professional workforce; knowledge supports for high-tech and lack of professional networks to proceed smart city planning and project that containing regional characteristics. This paper aims to examine the effective way of urban regeneration for small and medium-sized cities through smart city planning and strategy. As an important case, this paper looks at the 'Smart City Challenge' competition that was hosted by the US Department of Transportation in 2015. It examines the background and operation process of the smart city challenge competition, and then analyses each city's strategy and characteristics of seven finalists. This paper highlights the several key lessons to Korean cities: 1) the importance of national government's support in financial and professional resources; 2) the cooperation with local governments and IT corporations which provides realistic and detailed technical solutions; 3) the holistic and integrated approach to urban regeneration starting from transportation issues; 4) the necessity of the government's clear visions and guidelines toward the smart city.

• Korean Architects
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• s.515
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• pp.72-76
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• 2012

미국에서의 친환경적이고 지속가능한 도시설계 사례를 중심으로 통합적인 친환경 설계 프로세서에 대해 살펴보고 우리나라 친환경 설계에의 시사점을 제시하고자 한다. 이번 호에서는 세번째 사례로 Transbay Transit Center Master Plan을 소개하고자 한다.

• Korean Architects
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• s.517
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• pp.68-71
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• 2012

미국에서의 친환경적이고 지속가능한 도시설계 사례를 중심으로 통합적인 친환경 설계 프로세스에 대해 살펴보고 우리나라 친환경 설계에의 시사점을 제시하고자 한다. 이번 호는 마지막 완결편으로 지금까지 4회 연재한 사례들에 대한 시사점을 종합하고자 한다.

• Korean Architects
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• s.514
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• pp.68-71
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• 2012

미국에서의 친환경적이고 지속가능한 도시설계 사례를 중심으로 통합적인 친환경 설계 프로세스에 대해 살펴보고 우리나라 친환경 설계에의 시사점을 제시하고자 한다. 이번 호에서는 두번째 사례로 Parkmerced Vision Plan을 소개하고자 한다.

• Korean Architects
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• s.516
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• pp.67-71
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• 2012

미국에서의 친환경적이고 지속가능한 도시설계 사례를 중심으로 통합적인 친환경 설계 프로세스에 대해 살펴보고 우리나라 친환경 설계에의 시사점을 제시하고자 한다. 이번 호에서는 네번째 사례로 University of California, Merced Master Plan을 소개하고자 한다.

• Journal of Fisheries and Marine Sciences Education
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• v.22 no.4
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• pp.589-603
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• 2010

The purpose of this study is to develop a integrated(fusion) utilization model aimed at maximizing the development/management functions of urban estuarine area and to present an integrated concept by analyzing the existing document and data. The main points of this study are as follows: 1) The integrated utilization model suggested in this paper goes beyond the existing idea of sustainable utilization and conservation, putting an emphasis on rational decision-making in estuary management and peaceful coexistence between human and nature. 2) Policies for utilization/development/conservation/regeneration of urban estuarine area include the establishment of communication system between human and nature and a safety net considering both human and nature, the support for environment-friendly community development and the importance of preserving valuable ecosystem and wetland habitat. 3) Lastly, this study suggested that the major tasks for the fusion utilization model development are the integrated management of estuary areas, the conservation and preservation of wetland ecosystem, proper utilization of estuary's productivity, and the introduction and action plans of the integrated management model including the best way to address contamination and disaster management.

• Journal of Periodontal and Implant Science
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• v.37 no.3
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• pp.511-522
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• 2007

Introduction : The purpose of this study was to evaluate the possibility of the acellular dermal matrix (ADM) as a barrier membrane for bone regeneration, and to evaluate the osteogenic effect of ADM as a carrier system for rhBMP-2 in the rat calvarial defect model. Materials and Methods: An 8-mm, calvarial, critical-size osteotomy defect was created in each of 60 male Spraque-Dawley rats(weight $250{\sim}300g$). Three groups of 20 animals, each received either rhBMP-2(0.025mg/ml) in an ADM carrier, ADM only, or negative surgical control. And each group was divided into 2- and 8-weeks healing intervals. The groups were evaluated by histologic and histomorphometric parameters(10 animals/group/healing intervals). Data were expressed as $means{\pm}standard$ deviations($m{\pm}SD$). Comparisons between experimental and control groups were made using two-way ANOVA and post hoc t-test. Comparisons between 2 weeks and 8 weeks were made using paired t-test. The level of statistical difference was defined as P< 0.05. Results : The ADM group and rhBMP-2/ADM group results in enhanced local bone formation in the rat calvarial defect at both 2 and 8 weeks. The amount of defect closure and new bone formation were significantly greater in the rhBMP-2/ADM group relative to ADM group(P<0.05). At 8 weeks, the majority of ADM in the defect was contracted, and integrated with surrounding host tissues. In addition, host cell infiltration and neovascularization of the ADM in the absence of an inflammatory response were observed, and the newly formed bone around ADM showed a continuous remodeling and consolidation. Conclusion : The results of the present study indicated that ADM may be used as a barrier membrane for bone regeneration and that may be employed as a delivery system for BMPs.

• Journal of Periodontal and Implant Science
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• v.51 no.1
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• pp.18-29
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• 2021

Purpose: The aim of this study was to compare the characteristic expression patterns of advanced periodontitis in 2 cohort data sets analyzed using different microarray platforms, and to identify differentially expressed genes (DEGs) through a meta-analysis of both data sets. Methods: Twenty-two patients for cohort 1 and 40 patients for cohort 2 were recruited with the same inclusion criteria. The 2 cohort groups were analyzed using different platforms: Illumina and Agilent. A meta-analysis was performed to increase reliability by removing statistical differences between platforms. An integrative meta-analysis based on an empirical Bayesian methodology (ComBat) was conducted. DEGs for the integrated data sets were identified using the limma package to adjust for age, sex, and platform and compared with the results for cohorts 1 and 2. Clustering and pathway analyses were also performed. Results: This study detected 557 and 246 DEGs in cohorts 1 and 2, respectively, with 146 and 42 significantly enriched gene ontology (GO) terms. Overlapping between cohorts 1 and 2 was present in 59 DEGs and 18 GO terms. However, only 6 genes from the top 30 enriched DEGs overlapped, and there were no overlapping GO terms in the top 30 enriched pathways. The integrative meta-analysis detected 34 DEGs, of which 10 overlapped in all the integrated data sets of cohorts 1 and 2. Conclusions: The characteristic expression pattern differed between periodontitis and the healthy periodontium, but the consistency between the data sets from different cohorts and metadata was too low to suggest specific biomarkers for identifying periodontitis.

• Journal of the Society of Disaster Information
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• v.15 no.2
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• pp.175-185
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• 2019

Purpose: The purpose of this study is to propose a direction planning integrated waterfront cultural city in terms of urban economic revitalization through regeneration of former industrial harborfront and the creation of cultural living spaces based on regional history in order to pursue urban activities. Method: Analyzing planning waterfront and historical cultural space based on MM21's development policy and strategy under the growth process and development of Yokohama. Results: MM21 is the core public project out of the six major projects promoted by Yokohama, which is on the brink of satellite cities for the expansion of Tokyo with a goal of qualitative transformation of former harbor. It is planned to be developed as a creative cultural waterfront city for an integrated urban development. Conclusion: Planning waterfront cultural city, which takes advantage of the former harbor city derived through MM21 analysis, provides the cityscape towards the sea and the port via the viewing point and opens the waterfront open to the port and the sea Space and Esplanade landscape development, preservation of historic buildings and cultural assets, recycling as cultural art space, waterfront space planning that cooperates with public culture art and pedestrian network.