• 셀메드
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• 제5권4호
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• pp.27.1-27.6
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• 2015

Literatures and experimental studies have shown that Prunella has an effect on anti-hypertension, however, its components are complicated, so that it is still difficult to clear the specific roles of its various components in blood pressure regulation in. So we decide to systematically study the anti-hypertension mechanism of Prunella. We integrated multiple databases and constructed molecular interaction network between the chemical constituents of Prunella Vulgaris and hypertension based on entity grammar systems model. The network has 262 nodes and 802 edges. Then we infer the interactions between chemical compositions and disease targets to clarify the anti-hypertension mechanism. Finally, we found Prunella could influence hypertension by regulating apoptosis, cell proliferation, blood vessel development and vasoconstriction, etc. Thus this study provides reference for drug development and compatibility, and also gives guidance for health care at a certain extent.

• 한국병원경영학회지
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• 제16권2호
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• pp.78-97
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• 2011

The purpose of this study is to analyze activating factors of medical tourism at Busan, and then decide on priority on the factors. As research methods, this study deduced priority of specialists' opinions by AHP analysis technique through structuralized questionnaire on the medical tourism's factors having been suggested from existing prior studies. The analysis results were same as followings. First, as a result of analysis on the main criteria, relative levels of importance were appeared high such as 'competitiveness', 'policy assistances from the government', 'medical care's infrastructure', and 'connectedness with regions' in order. Second, as a result of integrated results analyzing detailed criteria on the main evaluation standards, relative levels of importance were appeared high such as 'medical quality', 'health-related institution's improvement', 'medical infrastructure', 'medical charge', 'tourism-related institution's improvement', 'convenience', 'medical cooperation possibilities', and 'local industry compliance' in order. In conclusion, it is judged that activation of medical tourism shall be propelled after considering relative levels of importance on many policies or activating factors same as suggested in this study.

• 산업경영시스템학회지
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• 제38권1호
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• pp.52-64
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• 2015

Korea ocean research stations manage the weather and environmental data collected from coastal and ocean areas to provide short-term and long-term ocean forecasts. The purpose of this paper is to analyze and quantify economic benefits of the ocean research stations with sensors to observe physical, chemical, and biological data. The construction and operation of an integrated ocean observation station is expected to reduce uncertainty about ocean and coastal areas and to improve the quality of ocean forecasts. The economic benefits are mainly come from improved search and rescue operations, ocean pollution management, yellow dust management, and improved productivity in ocean-related industries. In addition, an input-output analysis is performed to evaluate the economic impacts of ocean research stations nationwide. The analysis shows that the system can contribute to industries such as fishing, maritime and air cargo, medical and health care.

• 대한간호학회지
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• 제28권1호
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• pp.37-46
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• 1998

Recently the concept of 'empowerment' not only attracts attention in the area of management but also is considered as an useful concept in the areas of nursing theory. practice, education, and research. The purpose of this paper is to clarify the meaning of the concept 'empowerment'. More concretely, it is to find the concept that can be applied appropriately to the area of nursing management. This study uses Walter & Avant's(1983) process of concept analysis. The attributes of empowerment based on the concept can be defined concisely as follows : 1. a dynamic and interaction process 2. a partnership which values self and others : power shaving 3. mutual decision-making using resources, opportunities, and authority 4. accept autonomy and responsibility Antecedents of empowerment consist of 1) mutual trust and respect, 2) education and support, 3) participation and commitment. In regard to the consequences of empowerment, it is expected to 1) positive self-esteem, 2) ability to set and reach goals, 3) the promotion of organization's effectiveness and productivity, 4) provide effective and high quality health-care, 5) a sense of hope for the future. The concept of empowerment is certainly believed that it will help future nurses since they needs an integrated technique that can treat acute and chronic patients' nursing, individuals, families, and communities. Therefore. it is necessary to develop the instrument including the defining attributes identified in this study. Also, it is need follow up study of this concept.

• The Korean Journal of Physiology and Pharmacology
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• 제5권1호
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• pp.99-105
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• 2001

It is well known that the inflammation of somatic tissues, bladder and colon can alter the sensitivity of primary afferents innervating these tissues. To see if uterine afferents also show altered sensitivity, we examined their responses to the algesic agent bradykinin before and after induction of uterine inflammation. Inflammation was induced by injecting the mustard oil into the uterine lumen of adult female rats. After induction of inflammation, the response latency to bradykinin did not change, but the duration and peak of the response and integrated impulse discharges during the response period increased significantly. Furthermore, after inflammation, the level of resting discharges of the afferents was much higher. These results are consistent with the idea that the inflammation can sensitize the uterine afferents.

• Clinical and Experimental Pediatrics
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• 제63권12호
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• pp.454-462
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• 2020

The Committee on Dyslipidemia of Korean Pediatric and Adolescents of the Korean Society of Pediatric Endocrinology has newly developed evidence-based clinical practice guidelines for dyslipidemia in Korean children and adolescents. These guidelines were formulated with the Grading of Recommendations, which include both the strength of recommendations and the quality of evidence. In the absence of sufficient evidence, conclusions were based on expert opinion. These guidelines are based on the 2011 National Heart, Lung, and Blood Institute Guidelines, which focus on the prevention of cardiovascular disease in children and draw from a comprehensive review of evidence. These guidelines contain the definition of and screening process for dyslipidemia and introduce new dietary methods: the Cardiovascular Health Integrated Lifestyle Diet (CHILD)-1, the CHILD-2-low-density lipoprotein cholesterol, and the CHILD-2-triglyceride. Potential drug therapies for dyslipidemia along with their main effects and doses were also included.

• 한국농촌건축학회논문집
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• 제23권1호
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• pp.27-34
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• 2021

The senior welfare centers should provide integrated welfare services to the elderly whose needs are in change. So this paper tried to find a direction for improvement by identifying the spatial organization of the centers which are in Yeosu, Suncheon and Gwangyang. Classification of spaces of senior welfare center followed the guidelines 2020 for senior welfare center from Ministry of Health and Welfare which are consultation, medical rehabilitation, day or short-term protection, social education, home welfare, employment, welfare and public relations and PR planning and by adding management and public space. The above factors are invested and analyzed. The results of the survey and analysis of seven senior welfare centers are as follows. First, in the survey, the spatial organization of the senior welfare centers surveyed showed that the larger the size is, the dominantly lager the social education space is. Second, the space for day or short-term care, and employment is less than 1% of the total area, and most senior welfare centers do not have a basic space for this. Third, the space related to home welfare and counseling is very small, and more than half of the senior welfare centers do not have space related to it.

• 생명과학회지
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• 제33권7호
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• pp.538-548
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• 2023

식물 천연추출물에서 항균력을 갖는 활성 물질을 분리하고 이를 구강 건강 관리 제품에 사용하려는 연구가 진행되고 있다. 본 연구에서는 유기용매를 사용하여 독활과 우방자로부터 추출한 복합 화합물에 대한 구강 감염균인 Streptococcus mutans의 특정 유전자 발현 변화를 분석하여 항균 기작을 분석하고자 하였다. 전사체 분석 결과, 두 가지 천연추출물에 의해 다양한 대사 및 생리 작용과 연관된 유전자의 발현이 공통적으로 증가하거나 감소하는 것으로 나타났다. 세 가지 유전자(SMU_1584c, SMU_2133c, SMU_921)는 공통적으로 높은 수준으로 발현되었으며, 특히 이 중 SMU_921 (rcrR)은 두 가지 sugar phosphotransferase system (PTS)의 전사 활성자로써 당원의 수송과 생물막 형성에 기여하는 것으로 알려져 있다. 또한, 우방자 추출물에 비해 다수의 유전자 발현 변화에 영향을 미치는 것으로 나타난 독활 추출물의 성분 분석을 진행하였고, 활성 분획의 가스 크로마토그래피-질량분석법(GC-MS)을 통해 두 가지 활성 단일 물질을 동정하였다. 물질 분리 과정에서 여러 유기용매 분획 중 hexane층(ACEH)의 항균 활성이 가장 높게 관찰되었다. 다양종 미생물 군집을 사용한 실험결과, S. mutans에 대한 ACEH의 항균 특이성이 관찰되었으나, 상대적으로 S. sanguinis와 S. gordonii의 생균수도 크게 감소하는 것으로 나타났다. 이러한 결과는 독활 천연추출물의 광범위한 항균 활성을 시사하며, 동정한 단일 물질의 항균 기작을 분석하여 맞춤형 항균 소재 개발에 중요한 기초 자료를 제공할 수 있다.

• 대한의용생체공학회:의공학회지
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• 제24권6호
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• pp.533-541
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• 2003

본 논문은 환자 진료정보 공유 시 환자의 개인 및 진료 정보 보호 문제점을 해결하기 위해서 여러 장의 진찰카드를 하나의 IC카드로 통합하기 위한 시스템을 개발하였다. 먼저, 진료정보 공유를 위한 최소데이터세트를 정의하였고, 이 최소데이터세트를 통합 병원 진찰 IC 카드에 구현하고 발급할 수 있는 발급 시스템을 개발했다. 환자의 개인정보 보안 및 인증을 위해서는 윈도우 2000 기반 전자서명 인증센터를 구축하고 3-DES 적용한 IC 카드 기반의 통합 병원 진찰 IC 카드를 개발했다. 기존 병원 전산시스템과 효율적인 연동을 위한 통합 병원 진찰 IC 카드에 의한 진료접수/예약 시스템을 개발했다. 본 연구에서 개발한 통합 병원 진찰 IC 카드 시스템을 11개 병원에서 1.000명의 환자에게 적용한 결과, 시범 대상 병원들의 환자 진료 접수/예약뿐 아니라 정보 공유의 안정적 확장을 도모할 수 있는 기반을 마련할 수 있었다.

• 한국통신학회논문지
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• 제37권8C호
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• pp.690-696
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• 2012

최근 원격진료의 필요성과 사용자의 서비스 요구사항이 증가함에 따라 보다 편리한 원격진료 서비스 제공 방법에 대한 연구가 다양한 분야에서 진행 중이다. 본 논문에서는 기존의 원격진료시스템과는 다르게 무선통신센서를 이용한 CPS(Cyber Physical System)기반의 음성통신과 생체정보시스템을 연동하여 거동이 불편한 고령자는 편리하게 무선으로 정보를 송수신하고, 원격지의 의료인을 위해 전달 받은 생체정보와 음성대화를 통해 진단의 정확도를 높일 수 있으며, 고령인의 건강정보를 선택적으로 저장하고 추후 의료인이 조회하여 상시 건강관리가 가능한 통합원격의료서비스를 제안한다. 본 연구를 통해 고령사회로 진입한 우리나라 상황에 맞는 고령친화적인 원격진료시스템을 구축하여 실버타운에 거주하는 고령인들을 위한 고령친화적인 의료서비스를 제공할 수 있을 것이다.