• Genomics & Informatics
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• 제15권4호
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• pp.123-127
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• 2017

Synonymous sites are generally considered to be functionally neutral. However, there are recent contradictory findings suggesting that synonymous alleles might have functional roles in various molecular aspects. For instance, a recent study demonstrated that synonymous single nucleotide polymorphisms have a similar effect size as nonsynonymous single nucleotide polymorphisms in human disease association studies. Researchers have recognized synonymous codon usage bias (SCUB) in the genomes of almost all species and have investigated whether SCUB is due to random nucleotide compositional bias or to natural selection of any functional exposure generated by synonymous mutations. One of the most prominent observations on the non-neutrality of synonymous codons is the correlation between SCUB and levels of gene expression, such that highly expressed genes tend to have a higher preference toward so-called optimal codons than lowly expressed genes. In relation, it is known that amounts of cognate tRNAs that bind to optimal codons are significantly higher than the amounts of cognate tRNAs that bind to non-optimal codons in genomes. In the present paper, we review various functions that synonymous codons might have other than regulating expression levels.

• 한국관개배수논문집
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• 제21권1호
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• pp.109-117
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• 2014

Multi water-loop system is the efficient customer centered facilities of water supply by utilizing the multi water resources. Multi water-loop system is divided into various types. The system is classified potable and non-potable type. Mostly, the potable type utilizes surface water and ground water. However, the non-potable type utilize the multi water resources, such as rain water, sea water, reclaimed water, etc. Selective intake is possible when characteristics of region, physiographic condition and purpose of use are considered. For instance, downtown type, new-city type, agriculture type, island type are available. For development and application of these multi water-loop system, standardization is needed. For standardization, several methods are given; design principles, selection and composition method of multi water-loop system structure, BIM/GIS application method, safety inspection method. Consequently, a road map of design standardization method can be established. In this road map, there are three parts for the standardization of multi water-loop system. Three parts are the considerations, base material and ways of standardization. Design standardization become close when this road map followed by someone who plan the multi water-loop system. In this way, loop system's development is more efficient and economic. In hereafter research, each type's characteristic will be analysed and standardization methods can be established.

• 유통과학연구
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• 제15권12호
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• pp.21-30
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• 2017

Purpose - This research approaches to the new niche market of medical tourism to investigate how factors of cultural similarity influence the international distribution management. This study also estimates the interaction effects of distribution channel on the relationships of facility attributes and customers' destination choice behavior. Research design, data, and methodology - We collected the sample of 881 potential customers from the more economically developed regions in China. Regression analysis is used to confirm the relationships in the research model. Results - The result shows that cultural similarity plays an important moderating role in the relationships of facility attributes and destination choice intention. For instance, power distance and masculinity interact with the distribution facility characteristics of medical quality and reputation to influence customers' selection of the destination country. Individualism, powder distance, and masculinity play moderating roles when social environment affects destination choice intention. Especially, all the elements of cultural similarity moderate the relationships between travel cost and destination choice intention. This research also proves that depending on distribution channel, determinants of distribution facility are the critical predictors of intention to select the medical service outside of China. Conclusions - The study enables managers to develop the more effective strategies reflecting the interaction effects of cultural similarity and distribution channel on customers' decision-making process.

• 한국항공우주학회지
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• 제39권12호
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• pp.1150-1159
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• 2011

신뢰도란 임의 시스템이 주어진 운용환경 하에서 의도한 기간 동안 의도된 기능을 정상적으로 수행할 확률로 정의된다. 신뢰도-중복 최적화 문제(RROP)는 비용, 무게 등의 제약내에서 시스템의 신뢰도를 최대화할 수 있는 최적의 부품을 선택하고, 부품수와 중복전략(활성/대기중복)을 결정하는 문제이다. 본 연구에서는 아리랑위성 2호의 다채널광학카메라(MSC) 시스템의 설계 구조를 바탕으로 RROP의 수리모형을 제시하고, NP-hard인 RROP의 해법으로써 병렬 개체군집최적화(PPSO) 알고리즘을 제안하였다. RROP 예제의 수치실험 결과는 계획된 수명기간에서 신뢰도를 최대화하는 시스템의 설계 구조를 제시한다.

• 융합보안논문지
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• 제16권1호
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• pp.39-48
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• 2016

경비업법이 제정된지 40년이 되었다. 그동안 시큐리티정책에 많은 변화가 있었으며 시큐리티 환경도 급변하였다. 경찰과 더불어 생활안전의 한 축을 담당하는 민간경비를 활성화시키고 지원하는 방향에서 전면적인 개정을 할 때가 되었다. 첫째, 시큐리티 환경를 변화를 반영하여 경비업법의 법명과 용어를 재정립할 필요가 있다. 즉, 시큐리티 컨설팅, 플랜너, 민간조사, 융합보안 등을 수용할 수 있도록 적절한 경비업무 범위 등을 확대할 필요가 있다. 둘째, 경비업법령의 오류를 시정하여 개정할 필요가 있다. 셋째, 경비업법령 중에서 불합리한 내용을 지닌 조항을 적절하게 개정할 필요가 있다. 넷째, 경비지도사의 선발, 교육, 선임 중에서 불합리한 문제를 시정하는 방향으로 개정할 필요가 있다.

• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2004년도 제5회 정기학술발표대회 논문집
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• pp.427-432
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• 2004

최근 건설시장의 경쟁이 치열해지고, 건설생산성을 향상시키는 것이 기업의 경쟁력 확보라는 인식이 높아짐에 따라 건설업에서도 생산성과 효율성에 대한 관심의 풍요도가 증대되고 있다. 본 연구에서는 기존의 생산성 측정 방식을 활용한 사례조사를 통해 생산성을 측정하고 측정된 내용에 근거하여 작업개선사항을 제시하였다. 제안된 개선사항은 시뮬레이션(simulation)기법을 동해 검증하였다. 본 논문의 의의는 생산성 측정을 분석하는데 있어 시뮬레이션 기법이 현장여건을 모두 고려한 최적의 대안은 아니지만 현장관리자로 하여금 상황에 적합한 최적의 작업방식을 선택하게하고 생산량을 예측할 수 있는 방법을 제시했다는 점에 있다.

• Earthquakes and Structures
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• 제8권6호
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• pp.1349-1362
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• 2015

This paper presents an analytical study aimed at evaluating the effectiveness of using buckling-restrained braces (BRBs) in mitigating the seismic response of a case study 6 storey reinforced concrete (RC) building. In the design of the BRBs with non-prismatic cross-sections, twelve combinations of ${\alpha}$ and ${\beta}$ design parameters that influence the strength and stiffness of the BRBs, respectively, were considered. The response of the structure with and without BRBs under earthquake ground accelerations were evaluated through nonlinear dynamic analysis. Two sets of ground motions representative of the design earthquake with 10% and 50% exceedance probability in fifty years were taken into account. By comparing the structural performance of the original and buckling restrained braced structures, it was observed that the use of the BRBs were very effective in mitigating the seismic response as a retrofit scheme. However, the selection of the strength and stiffness parameters of the BRBs had considerable effect on the response characteristics of RC structures. For instance, by increasing the value of ${\alpha}$ and by decreasing the value of ${\beta}$ of the buckling-restrained braces, the maximum deformation demand of the structures increased.

• 한국실내디자인학회:학술대회논문집
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• 한국실내디자인학회 2005년도 춘계학술발표대회 논문집
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• pp.255-256
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• 2005

For the students who specialize in interior design irrespective of their color susceptibility, it is prerequisite to precede a systematic curriculum in the first place on how to put the color theory to practical use. Therefore, this curriculum has its purpose to let the students study on how to put to practical use of their understanding of color as one of the finishing materials for interior design. The 16-weekschool days has been segmented into a theoretical study and practical training, This thesis has summed up the basic instance of the color theory, the first of the three basicpractical courses and presented its results to the students. In due course of this curriculum, the students were recommended to pick up one photo image of their selection out of which they could make out color palette based on their analysis of the photo image, so that they could study on how to apply their color palette to a three dimensional space. Firstly, through this course, they could experience the process for a color image that they had so far sensed subjectively and vaguely to become an objective inevitable result. Secondly, they studied on the process of how a two-dimensionalcolor image could be applied for a three-dimensional space. It is significant of this curriculum in the sense that the students become prepared through this study course with essential knowledge applicable to various interior designs in their future.

• International Journal of Computer Science & Network Security
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• 제21권9호
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• pp.212-222
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• 2021

Multiple waves of COVID-19 highlighted one crucial aspect of this pandemic worldwide that factors affecting the spread of COVID-19 infection are evolving based on various regional and local practices and events. The introduction of vaccines since early 2021 is expected to significantly control and reduce the cases. However, virus mutations and its new variant has challenged these expectations. Several countries, which contained the COVID-19 pandemic successfully in the first wave, failed to repeat the same in the second and third waves. This work focuses on COVID-19 pandemic control and management in Saudi Arabia. This work aims to predict new cases using deep learning using various important factors. The proposed method is called Deep Learning and Dynamic Weighing-based (DLDW) COVID-19 cases prediction method. Special consideration has been given to the evolving factors that are responsible for recent surges in the pandemic. For this purpose, two weights are assigned to data instance which are based on feature importance and dynamic weight-based time. Older data is given fewer weights and vice-versa. Feature selection identifies the factors affecting the rate of new cases evolved over the period. The DLDW method produced 80.39% prediction accuracy, 6.54%, 9.15%, and 7.19% higher than the three other classifiers, Deep learning (DL), Random Forest (RF), and Gradient Boosting Machine (GBM). Further in Saudi Arabia, our study implicitly concluded that lockdowns, vaccination, and self-aware restricted mobility of residents are effective tools in controlling and managing the COVID-19 pandemic.

• 건축역사연구
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• 제30권3호
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• pp.33-44
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• 2021

San-ja is one of the main members consisting of the roof of traditional wooden buildings in Korea. In this study, the regional characteristics of the materials used in San-ja and changes of the materials over time were examined. To this end, 123 documents on the repair of wooden architectural heritage recorded since the 1950s were reviewed. It was found that there was a difference in the San-ja material by region because of the diversity in the conditions of material supply. For instance, bamboo was the most frequently used material in Jeollanam-do province because it was readily available. However, with the development of transportation and vehicle, the regional characteristics have disappeared. As a result, the material has been unified with bamboo now. This is because bamboo is specified as a representative material in the specification or the convenience of construction is prioritized. In addition, the social and economic conditions at the time of repair had an influence on the selection of the San-ja materials.