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Production of $^{11}C$ labeled Radiopharmaceuticals using $[^{11}C]CO_2$ Produced in the KOTRON-13 (한국형 사이클로트론(KOTRON-13)을 이용한 $[^{11}C]CO_2$ 생산과 다양한 $^{11}C$-표지 방사성의약품 생산 적용)

  • Lee, Hong Jin;Park, Jun Hyung;Moon, Byung Seok;Lee, In Won;Lee, Byung Chul;Kim, Sang Eun
    • The Korean Journal of Nuclear Medicine Technology
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    • v.16 no.2
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    • pp.106-109
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    • 2012
  • Purpose : The KOTRON-13 cyclotron was developed and installed in regional cyclotron centers to produce short-lifetime medical radioisotopes. However, this cyclotron has limited capacity to produce $^{11}C$ so far. In present study, we developed an effective $^{11}C$ target system combining with fluorine-18 target and applied to the production of various $^{11}C$ radiopharmaceuticals. Materials and Methods : To develop the optimal $^{11}C$ target system and effective its cooling system, we designed the $^{11}C$ target system by Stopping and Range of Ions in Matter (SRIM) simulation program and considered the cavity pressure during irradiation at target grid. In this investigation, we modified target materials, cavity shapes and the position of cooling system in $^{11}C$ target and then evaluated $[^{11}C]CO_2$ production at different beam currents, thickness of the target foil, oxygen content of nitrogen gas and target gas loading pressure. Also, we evaluate the production of several $^{11}C$ radiopharmaceuticals such as [$^{11}C$]PIB, [$^{11}C$]DASB, and [$^{11}C$]Clozapine. Results : $[^{11}C]CO_2$ was produced about 74 GBq for 30min irradiation at 60 ${\mu}A$ of beam current as following conditions: thickness of the target foil: 19 nm HAVAR, oxygen content of nitrogen: under 50 ppb, target gas loading pressure: 24 bar. Additionally, the cooling system was stable to produce $[^{11}C]CO_2$ at high beam current. The radiochemical yields of [$^{11}C$]PIB, [$^{11}C$]DASB, and [$^{11}C$]Clozapine showed about 26-38% with over 127 GBq/umol of specific activity. Conclusion : The carbon-11 target system in the KOTRON-13 cyclotron was successfully developed and showed stable production of $[^{11}C]CO_2$. These results showed that our $^{11}C$ target system will be compatible with other commercial system for the routine $^{11}C$ radiopharmaceuticals production in the KOTRON-13 cyclotron.

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Development of Integrated Process Management System for Pump Dredge (펌프식 준설선의 통합공정관리시스템 개발)

  • Jeong, Dae-Deuk;Lee, Joong-Woo;Cho, Jeung-Eon
    • Journal of Navigation and Port Research
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    • v.26 no.1
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    • pp.146-151
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    • 2002
  • Efficiency of dredging work depends on the types of equipment used, the sediments encountered, whether the work to be performed is new or for maintenance, pre and/or post hydrographic surveying and so forth. Among those, surveying accuracy which is directly determined by the control of the dredge's position and depth surveying accuracy being surveyed at the dredging point are important factors. The purpose of this study is to develop an integrated process management system for pump dredge. The system is composed of 4 sub-systems such as LADGPS for dredge positioning dredging point determination, tidal gauge and angular depth sensor for depth determination, and GIS and ENC process management. The process management system for pump dredge developed was installed on the pump dredge "EUNJIN PD-2" but is now producing work data for comparison with performance of the existing dredge. The data retrieved from the pump dredge process management system up to now shows similar result from the grab dredge management system which was developed previously. It is easy to operate, achieves good accuracy with only 45cm unevenness, reduces working perioa by 20 percint,. More precise evaluation of the system comes later after the dredging work is completed.completed.

Study of Cross Correlation Using DRS(Delayed Reference Sample) for Precision Time Measurement of Input Signal on Multilateration (다변측정감시시스템 신호 입력 시각 정밀 측정을 위한 DRS(Delayed Reference Sample)를 이용한 Cross Correlation 방안 연구)

  • Chang, Jae-Won;Lee, Sang Jeong
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.46 no.3
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    • pp.244-250
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    • 2018
  • Multilateration acquires the transponder signal of target from receivers installed on the ground and calculates the position of the target using the difference of the signal acquisition time of each receiver. One of the factors that influence the positioning accuracy of Multilateration using the TDOA calculation method is the error due to the precision measurement of signal input time. When measuring the signal input time at the receiver, the input signal is sampled using the reference clock of the receiver and a reference sample having the same sampling rate is applied to the cross correlation technique. Therefore, the accuracy of the signal input time is proportional to the reference clock. In this paper, the algorithm for precisely measuring the signal input time by performing cross correlation between the input signal of the receiver and DRS(Delayed Reference Sample) is proposed. In order to verify this, we implemented the pulse signal of the transponder that is transmitted from the target using Matlab. Through the simulation, cross correlation between the proposed DRS and the input signal was performed. From this result, the performance of the precise measurement of signal input time was analyzed.

The Study on Design of Circuit Card Assembly on Servo Control Unit for Automated Resupply Vehicle K56 (K56 탄약운반장갑차용 서보제어기의 회로카드조립체 설계에 관한 연구)

  • Lee, Ju-Seung;Kim, Seong-Jin;Bae, Gong-Myeong;Kwon, Soon-Mo;Park, Hyean-Jo;Choi, Jun-Sok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.12
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    • pp.102-109
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    • 2019
  • This paper describes the design of the circuit card assembly to eliminate the communication error on a servo control unit installed in the automated resupply vehicle K56. K56 is a weapon system that automates the supply and loading of ammunition on the K-55A1 self-propelled artillery. As the core item responsible for ammunition movement control, the servo control unit is required to have good communication stability and reliability, but the conventional unit has recognized a problem that communication error intermittently occurs, resulting in an emergency stop phenomenon. We analyzed the communication signal of the servo control unit and identified the failure cause of the circuit card assembly to solve this problem. In addition, the signal interference in data/address line of the circuit card assembly was confirmed through analysis of the failure cause, and redesigned to avoid the interference, such as adjustment of the distance between communication lines and position change. Finally, the proposed cause analysis and redesign were verified through the component of servo control unit and attachment test on K56. We expected these study results to be used as reference for the design of other similar items.

Experiment on Camera Platform Calibration of a Multi-Looking Camera System using single Non-Metric Camera (비측정용 카메라를 이용한 Multi-Looking 카메라의 플랫폼 캘리브레이션 실험 연구)

  • Lee, Chang-No;Lee, Byoung-Kil;Eo, Yang-Dam
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.26 no.4
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    • pp.351-357
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    • 2008
  • An aerial multi-looking camera system equips itself with five separate cameras which enables acquiring one vertical image and four oblique images at the same time. This provides diverse information about the site compared to aerial photographs vertically. The geometric relationship of oblique cameras and a vertical camera can be modelled by 6 exterior orientation parameters. Once the relationship between the vertical camera and each oblique camera is determined, the exterior orientation parameters of the oblique images can be calculated by the exterior orientation parameters of the vertical image. In order to examine the exterior orientation of both a vertical camera and each oblique cameras in the multi-looking camera relatively, calibration targets were installed in a lab and 14 images were taken from three image stations by tilting and rotating a non-metric digital camera. The interior orientation parameters of the camera and the exterior orientation parameters of the images were estimated. The exterior orientation parameters of the oblique image with respect to the vertical image were calculated relatively by the exterior orientation parameters of the images and error propagation of the orientation angles and the position of the projection center was examined.

Simulation of Various Baffle Types in a Constructed Wetland Sedimentation Tank using CFD (CFD를 이용한 Hybrid 인공습지의 초기침강지 저류판 구조 모의)

  • Noh, Taegyun;Jeon, Jechan;Kim, Lee-Hyung
    • Journal of Wetlands Research
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    • v.18 no.3
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    • pp.324-329
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    • 2016
  • Constructed wetlands are widely applied in urban and rural areas for various purposes such as pollutants reduction, acquisition of eco-spaces and habitats, flooding reduction, acquisition of water resources and environmental education. Since the design of constructed wetlands utilizes ecosystems, special consideration must be given to ecological mechanisms, environmental mechanisms and hydrological mechanisms. To ensure the sustainable functionality of constructed wetlands, it is necessary to achieve stable flow rate and velocity, and remove sediments to ensure sufficient space for detention. To enhance the efficiency of constructed wetland sedimentation basins, this study determined the optimal position for baffle installation, and applied Computational Fluid Dynamics (CFD) to the cross-sectional design of wetlands. CFD analysis revealed that the decrease in flow velocity with baffle installation enhanced the efficiency of sedimentation of particulate matters. Vertical baffles had higher sedimentation efficiency than those with an inclined angle. When vertical baffles were installed in the sedimentation basin of a hybrid constructed wetland to reduce non-point source pollutants in urban areas, the average flow velocity within the basin decreased by 10~30%, while the sedimentation efficiency improved by 1.3~1.5 times. The application of CFD to constructed wetlands is expected to improve the cost efficiency of designing hybrid constructed wetlands with high removal efficiency.

Accuracy of Parcel Boundary Demarcation in Agricultural Area Using UAV-Photogrammetry (무인 항공사진측량에 의한 농경지 필지 경계설정 정확도)

  • Sung, Sang Min;Lee, Jae One
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.34 no.1
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    • pp.53-62
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    • 2016
  • In recent years, UAV Photogrammetry based on an ultra-light UAS(Unmanned Aerial System) installed with a low-cost compact navigation device and a camera has attracted great attention through fast and accurate acquirement of geo-spatial data. In particular, UAV Photogrammetry do gradually replace the traditional aerial photogrammetry because it is able to produce DEMs(Digital Elevation Models) and Orthophotos rapidly owing to large amounts of high resolution image collection by a low-cost camera and image processing software combined with computer vision technique. With these advantages, UAV-Photogrammetry has therefore been applying to a large scale mapping and cadastral surveying that require accurate position information. This paper presents experimental results of an accuracy performance test with images of 4cm GSD from a fixed wing UAS to demarcate parcel boundaries in agricultural area. Consequently, the accuracy of boundary point extracted from UAS orthoimage has shown less than 8cm compared with that of terrestrial cadastral surveying. This means that UAV images satisfy the tolerance limit of distance error in cadastral surveying for the scale of 1: 500. And also, the area deviation is negligible small, about 0.2%(3.3m2), against true area of 1,969m2 by cadastral surveying. UAV-Photogrammetry is therefore as a promising technology to demarcate parcel boundaries.

Experimental Study of Workpiece Temperature Variation in Reheating Furnace (재가열로에서 소재 온도 변화의 실험적 분석)

  • Lee, Chunsik;Lee, Jaeyong;Ryu, Bo-Hyun;Yeom, Choongsub;Rhim, Dong-Ryul
    • Journal of Energy Engineering
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    • v.26 no.4
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    • pp.100-106
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    • 2017
  • The materials of SUS304 and SS400 are adopted for prediction of workpiece temperature variation according to ambient temperature in a reheating furnace. Five thermocouples were installed in a depth direction inside the material, and the ambient temperature was raised to 1200 Celsius degrees. As a result, the material average temperature reached more than 1150 Celsius degrees, and the surface and inside of workpiece locally showed a temperature difference of more than 10K. In order to verify the experimental results, numerical analysis was conducted by applying a thermal model, and the error of numerical simulation compared with the experimental results was within the range of 15K at the average outlet temperature. Also, the error was relatively higher in the SS400 material, which has a larger specific heat change than the SUS304 material. In conclusion, the workpiece temperature in the reheating furnace can be achieved through the atmospheric temperature control, and it is experimentally proved that the material temperature change according to the atmospheric temperature can be estimated within about 3% error range at the outlet position using a thermal model.

A Study on Changes in the Space Composition of Each Room in Bukchon Hanok - Focused on Open-Hanoks and Publicly Puhased Hanoks - (북촌한옥 각 실의 용도 및 공간변화 특성에 관한 연구 - 개방한옥과 공공매입한옥을 중심으로 -)

  • Kim, Do-Yeon;Oh, He-Kyung
    • Journal of Families and Better Life
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    • v.26 no.2
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    • pp.115-127
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    • 2008
  • The purpose of this study was to examine the characteristics of change in the composition of indoor spaces in Korean-style houses which have been repaired and improved extensively through the 'Bukchon Improvement Project' and are being utilized for public purposes. For this, we conducted a field survey through visiting the house sites from the 5th to the 26th of May, 2006. Conclusions drawn from this study are as follows. Bukchon Korean-style houses maintain centripetal space composition, in which the rooms surround the court. Centering on the court, the hierarchy of spaces is determined, and the hierarchy of spaces and the composition of internal layout are restructured centering on the court and the main hall without change in direction and position. The main hall is sometimes converted to a room, but it maintains an open space relation with other spaces centering on the court, and therefore, even after its use has been changed, it is still the most Korean-style space. In addition, with floor heating, the common sitting-style life is maintained continuously although the rooms have been converted and standing-style furniture is used. In this way, publicly promoted policies for Korean-style houses are allowed within the limit that the appearance is maintained and the internal spaces do not change the overall structure. However, in order to maintain the tradition of Korean-style houses and utilize them as various spaces, the following supplementations are necessary. First, the main hall and the inner court of a Koreanstyle house should be utilized actively. The court sometimes keeps individuals' privacy or expands the space by extending the view to outdoor spaces, and is sometimes used as an open space through interconnection between the inside and the outside of the house. Second, consideration should be given to vertical spaces. Horizontal expansion causes a change of floor plan. Thus, space should be secured using various cross-sectional changes, such as a kitchen and a loft over the kitchen. Third, structure should be changeable in order to adjust the size of spaces. Thus, through research on traditional windows, we need to develop changeable walls that can be installed and removed easily according to the use of spaces.

A Study on the Traditional Planting Prototype of Haengdan(杏壇) and Natural Monumental Value of Ginkgo Tree in Sejong-ri (전통재식 행단(杏壇)의 원형과 세종리 은행나무의 천연기념물적 가치 연구)

  • Shin, Hyun-Sil;Choi, Byoung-Ki
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.38 no.1
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    • pp.36-44
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    • 2020
  • This study analyzed the Planting Prototype of Haengdan(杏壇)is the One of the traditional planting techniques and the value of natural monument plant and derived the value of the ginkgo tree in Sejong-ri as a natural monument. The results are as follows; First, ginkgo trees have high environmental adaptability, practicality and visual value. There were also many ginkgo trees that were deeply related to Confucian and Buddhist ideas. Ginkgo trees accounted for the largest portion of the number of old tree designated as natural monuments in recognition of their value. Second, after analyzing the historical and cultural values of ginkgo trees, ginkgo trees became the place of gardens and buildings by symbolizing Confucius(孔子)' Confucian ideas. In Buddhism, it was related to the creation of temples or the achievements of ancient monks. The people had a symbol of the prosperity of their offspring and the succession of the family. Third, in 1024 gongdobo, the grandson of Confucius, rebuilt the shrine, installed the platform in the central position and planted ginkgo trees. It originated from what he called "the "haengdan(杏壇)." The tree was then recorded as "heungheang(紅杏)" which was written by Wang Jae-jin's poetry during the Ming Dynasty. Thus it was misused as apricot tree. The cause of this is due to the same kanji reading. or it can be seen as influence on the taoism. But Korea has been sticking to the use of the first ginkgo trees. Forth, biologically, the Sejong-ri ginkgo tree is characterized by the composition of a pair of male trees. The landscape is contrasted with the twisted male tree and vertical female trees. In addition, in terms of authenticity and integrity, the relationship between Admiral Im, Nan-Su(林蘭秀) of the Goryeo Dynasty and the ginkgo tree is found in various literature.