• Title/Summary/Keyword: Innovation in S&T

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On the Relationship between Evaluation Indexes and Firms' Performance: An Empirical Study on Venture Firms in Korea (중소벤처기업성과와 국내 지원기관들의 평가지표간의 상관관계에 관한 실증연구)

  • Choi, Jong-Yeon;Yang, Dong-Woo
    • Journal of Korea Technology Innovation Society
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    • v.9 no.4
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    • pp.812-841
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    • 2006
  • Previous studies have shown that the ex-ante financial ratios, mainly used by financial institutions for loan evaluation purpose, are related to the ex-post finn's performance of venture firm's. The main objective of this study is to examine whether non-financial variables such as 'technology', 'marketability', and 'other business indexes' have extra explanatory power in forecasting the ex-post firm's performance of small and medium size venture firm's in Korea. The implications and results of this study are expected to be useful in loan evaluation, investment decision and internal management decisions of venture firms. Among small and medium sized manufacturing firms funded in the year of 1999 through 2005, 416 firms are selected for our analysis. The relationship between evaluation indexes and firm's success/failure is investigated using binary logistic regression analysis and factor analysis with an aid of SPSS program. The summarized results are as follows. First, current evaluation model, used for loan evaluation purpose for small and medium size manufacturing firms show the same discriminatory power as previous prediction model. Second, among the tested additional variables, significant indices are 'technological capability of CEO', 'managerial capability of CEO', and 'business feasibility'. Third, while previous studies on evaluation structure had 3 factors, this study showed that valuation's structure has 6 factors.

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Studies on Whitening and UV Damage Protection Effect of the Pterin Compounds (테린계 화합물의 미백 및 자외선 손상방어 효능에 관한 연구)

  • Kim, Nam-Kyoung;Kim, Mi-Hwa;Kang, Nae-Im;Choi, Shin-Wook
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.33 no.1 s.60
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    • pp.53-60
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    • 2007
  • (6R)-5,6,7,8-tetrahydrobiopterin (6BH4) cofactor is essential for various process, and is present in probably every cell or tissue of higher organism. 6BH4 is required lot various enzyme activities, and for less defined functions at the cellular level. And it is well known about the antioxidant effects as a non-protein compound. Recently, scientists proposed another roles for 6BH4 in melanogenesis. 6BH4 is a well known tyrosinase inhibitor. In this study, we found that methyl-BH4 and 6BH4 have antioxidant activities and inhibitory activity for melanin synthesis. These pterin compounds were not toxic in HaCaT and B16F10 cells and showed scavenging activity against DPPH radicals. We also showed that pterin compounds decreased protein levels of tyrosinase and TRP-1. In a clinical test, pterin compounds showed the significant skin whiteining effect after treatment for 3 weeks. Furthermore pterin compounds significantly suppressed the UVB-induced expression of PGE2 and IL-6 genes induced UVB In HaCaT and inhibited UVB-induced melanogenesis in B16F10 cells. These results showed the effect of pterin compounds as a cosmeceutical ingredient.

A Study on Clothing Attitude of Chinese Students in Korea - Focused on Gender, Socio-economic Level and Resident Period - (한국내 중국인 유학생의 의복태도 연구 - 성별, 사회경제적 수준별, 한국거주기간별 -)

  • Yu, Ji-Hun
    • Journal of the Korea Fashion and Costume Design Association
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    • v.11 no.2
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    • pp.153-168
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    • 2009
  • The purpose of this study was to identify the clothing attitude of Chinese students in korea according to gender, socio-economic level and resident period. The survey was conducted from October 30th to November 25th 2008, and 267 questionnaires were used for the analysis. Data were analyzed by factor analysis, T-test, ANOVA, Duncan's Multiple Range Test with SPSS 12.0. The results were as follows: 1. Most of Chinese students were middle-class Han race and they have been staying in Korea for 3 years. 2. Fashion leadership was classified as Innovation and Opinion leading factor; conformity as Nonconformity, Identification, and Norm consciousness; pursuit benefit as Practicality, Economy, and Aesthetic. 3. The Innovation factor was highly marked in female student group, the Opinion leading factor was higher in high-class group, and the pursuit benefit factor was significantly different between less than three years group and over three years group who have been in Korea. 4. We need to recommend best-design clothes for high-class Chinese female students who have been in Korea for over three years, and low-price clothes for less than 3 years.

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Two-sided 마켓 관점에서 분석한 통신방송융합 환경하의 방송매체 플렛폼 경쟁

  • 황준석;김기현;장태진
    • Proceedings of the Technology Innovation Conference
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    • 2006.02a
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    • pp.78-102
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    • 2006
  • Networks, services and industries have been converging with the advent of digital convergence by technology advancements of digitalization, broadband and interactivity in the areas of information-communication and broadcasting technologies. Especially, this convergence of technology and market has been blurring the boundary of telecommunication and broadcasting sectors, and the severe competition seems to be inevitable due to the lack of the differentiation in broadcasting media and contents. In this study, we regard the competition phenomenon in the digital convergence between telecommunication and broadcasting as the platform competition in two-sided markets which have been actively studied since 2000, and analyzed it using modified Hotelling's location model. According to the analysis of platform competition on the effects of the differentiation of platform (t) , killer component (μ) and component compatibility (θ) , it is shown that two differentiated platforms are simultaneously used in case of the decrease of substitution effects, and the profit of platform with killer contents is increased, but the profit of platforms with higher compatibility is decreased. The policy implication is that it is especially necessary to modify the policy and regulation on media contents considering the growing competition in media. On the other hand, differentiated and reasonable policy is required to make fair competition and active market environment.

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A Study on the Technical and Administrative Innovation of Library Organization in the Perspective of the Contingency Theory (도서관조직의 기술혁신 및 행정혁신에 관한 조직상황론적 연구)

  • Hong Hyun-Jin
    • Journal of the Korean Society for Library and Information Science
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    • v.25
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    • pp.343-388
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    • 1993
  • The ability of any organization to innovate itself in a rapid change of environment means the existence of the organization. Innovative activity is achieved in different ways according to the objectives of organization. the characteristics of external environmental factors. and various attributes in organization. In the present study. all the existing approaches to the innovative nature of organization were synthetically compared to each other and evaluated: then. for a more rational approach. a research model was built and suggested by establishing the inclusive variables of the innovative nature of library organization and categorizing the types of such nature. Additionally. an empirical. analytical study on such a model was done. That is. paying regard to the fact that innovation has basically a close relation with the circumstantial factors of organization. synthetic, circumstantial relations were clarified. considering the external environmental factors and internal characteristics of organization. In the study. the innovation of library organization was seen in two parts i.e .. the feasible degree of technical innovation and the feasible degree of administrative innovation. Regarding the types of innovative implementation. according to the feasible degree of innovation, four types such as a stationary type. technic-oriented type, organization-oriented type. and technical-socio systematic type were classified. There were nine independent variables-i.e., the scale of organization. available resources of the organization, formalization, differentiation, specialization. decentralization, recognizant degree of the technical attribute. degree of response to the change of technical environment, and professional activities. There were three subordinate variables - i.e., technical innovation, administrative innovation. and the performance of organization. Through establishment of such variables, the factors which might influence the innovation of library organization were understood, and with the types of the innovative implementation of library organization being classified according to the feasible degree of innovation. the characteristics of library organization were reviewed in the light of each type. Also. the performance of library organization according to the types of the innovative implementation of library organization was analyzed. and the relations between the types of innovative implementation according to circumstantial variables and the performance of library organization were clarified. In order to clarify the adequacy of the research model in the methodology of empirical study, data were collected from 72 university libraries and 38 special libraries. and for a hypothetical test of the research model. an analysis of correlations, a stepwise regression analysis. and One Way ANOVA were utilized. The following are the major results or findings from the study 1) It appeared there is a trend that the bigger the scale of organization and available resources are, the more active the professional activity of the managerial class is, and the higher the recognizant degree of technical environment (recognizant degree of technical attributes and the degree of response t9 the change of technical environment) is, the higher the feasible degree of innovation becomes. 2) It appeared that among the variables influencing the feasible degree of technical innovation, the order from the variable influencing most was first, the recognizant degree of technical innovation: second, the available resources of organization: and third, professional activity. Regarding the variables influencing the feasible degree of administrative innovation from the most influential variable, it appeared they were the available resources of organization, the differentiation of organization. and the degree of response to the change of technical environment. 3) It appeared that the higher the educational level of the managerial class is, the more active the professional activity becomes. It seemed there is a trend that the group of library managers whose experience as a librarian was at the middle level(three years to six years of experience) was more active in research activity than the group of library managers whose experience as a librarian was at a higher level(more than ten years). Also, it appeared there is a trend that the lower the age of library managers is, the higher the recognizant degree of technical attributes becomes. and the group of library managers whose experience as a librarian was at the middle level (three years to six years of experience) recognized more affirmatively the technical aspect than the group of library managers whose experience as a librarian was at a higher level(more than 10 years). Also, it appeared that, when the activity of the professional association and research activity are active, the recognizant degree of technology becomes higher, and as a result. it influences the innovative nature of organization(the feasible degree of technical innovation and the feasible degree of administrative innovation). 4) As a result of the comparison and analysis of the characteristics of library organization according to the types of innovative implementation of library organization. it was indicated there is a trend that the larger the available resources of library organization, the higher the organic nature of organization such as differentiation. decentralization, etc., and the higher the level of the operation of system development, the more the type of the innovative implementation of library organization becomes the technical-socio systematic type which is higher both in the practical degrees of technical innovation and administrative innovation. 5) As a result of the comparison and analysis of the relations between the types of innovative implementation and the performance of organization, it appeared that the order from the highest performance of organization is the technical-socio systematic type, then the technic-oriented type, the organization­oriented type, and finally the stationary type which is lowest in such performance. That is, it demonstrated that, since the performance of library organization is highest in the library of the technical-socio systematic type while it is lowest in the library whose practical degrees in both technical innovation and administrative innovation are low, the performance of library organization differs significantly according to the types of innovative implementation of library organization. The present study has extracted the factors influencing innovation, classified systematically the types of innovative implementation, and inferred the synthetical, circumstantial correlations between the types and the performance of organization, and empirically inspected those factors. However, due to the present study's restrictive matters and the limit of the research design, results from the study should be more prudently interpreted. Also, the present study, as an investigative study of the types of innovative implementation, with few preceding studies, requires more complete hypothetical inference based on the results of the present study. In other words, if more systematical studies are given to understanding the relations, it will devote the suggestion and demonstration of a more useful theory.

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A Study on Technology Forecasting based on Co-occurrence Network of Keyword in Multidisciplinary Journals (다학제 분야 학술지의 주제어 동시발생 네트워크를 활용한 기술예측 연구)

  • Kim, Hyunuk;Ahn, Sang-Jin;Jung, Woo-Sung
    • Journal of the Korean Operations Research and Management Science Society
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    • v.40 no.4
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    • pp.49-63
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    • 2015
  • Keyword indexed in multidisciplinary journals show trends about science and technology innovation. Nature and Science were selected as multidisciplinary journals for our analysis. In order to reduce the effect of plurality of keyword, stemming algorithm were implemented. After this process, we fitted growth curve of keyword (stem) following bass model, which is a well-known model in diffusion process. Bass model is useful for expressing growth pattern by assuming innovative and imitative activities in innovation spreading. In addition, we construct keyword co-occurrence network and calculate network measures such as centrality indices and local clustering coefficient. Based on network metrics and yearly frequency of keyword, time series analysis was conducted for obtaining statistical causality between these measures. For some cases, local clustering coefficient seems to Granger-cause yearly frequency of keyword. We expect that local clustering coefficient could be a supportive indicator of emerging science and technology.

Induction of Apoptosis by Combined-treatment with Genistein and TRAIL in U937 Human Leukemia Cells (Genistein과 TRAIL의 복합처리에 의한 U937 인체 혈구암 세포의 Apoptosis 유도)

  • Choi, Yung-Hyun;Han, Min-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.9
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    • pp.1201-1207
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    • 2011
  • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been proposed as a potent tool to trigger apoptosis in cancer therapy. However, as many types of cancer cells remain resistant towards TRAIL-induced cytotoxicity, several combined therapy approaches aimed to sensitize cells to TRAIL have been developed. Genistein, a natural isoflavonoid phytoestrogen, has been shown to have anticancer activity by inducing cell cycle arrest at G2M phase as well as apoptosis in various cancer cell lines. In the present study, we showed that treatment with TRAIL in combination with subtoxic concentrations of genistein sensitized U937 human leukemia cells to TRAIL-mediated apoptosis. Combined treatment with genistein and TRAIL effectively activated caspases through Bid truncation (tBid) and down-regulation of cellular caspase-8 (FLICE)-like inhibitory proteinL (cFLIPL). However, the apoptotic effects of co-treatment with genistein and TRAIL were significantly inhibited by specific caspase inhibitors, which demonstrates the important role of caspases in apoptosis induced by genistein and TRAIL. Overall, our results indicate that genistein can potentiate TRAIL-induced apoptosis through down-regulation of cFLIPL and up-regulation of pro-apoptotic tBid proteins.

Inhibitory Effects of Illicium verum Hooker fil. Dichloromethane Fractions on Adipocyte Differentiation (팔각회향 dichloromethane 분획물에 의한 지방세포 분화 억제 효과)

  • Jeong, Hyun Young;Jeong, In Kyo;Kim, Nam Ju;Yun, Hee Jung;Park, Jung Ha;Kim, Byung Woo;Kwon, Hyun Ju
    • Journal of Life Science
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    • v.29 no.4
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    • pp.447-454
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    • 2019
  • Fat accumulation in adipocytes occurs through the process of adipogenesis in which preadipocytes differentiate into adipocytes. Obesity is a metabolic disorder caused by excessive accumulation of fat in the body, which increases the incidence of cardiovascular diseases, hypertension, type 2 diabetes, hyperlipidemia, and various cancers. Recently, inhibition of adipocyte differentiation was shown to be a potential antiobesity strategy. In this study, the inhibitory effect of dichloromethane fractions from Illicium verum Hooker fil. water extract on the differentiation of 3T3-L1 preadipocytes to adipocytes was investigated. Dichloromethane fractions from I. verum Hooker fil. significantly inhibited adipocyte differentiation when applied during the adipocyte differentiation process, as assessed by measuring fat accumulation using Oil-red O staining. In addition, dichloromethane fractions from I. verum Hooker fil. reduced important adipogenic transcription factors, such as CCAAT/enhancer binding protein α (C/EBPα), C/EBPβ, and peroxisome proliferator activated receptor γ (PPARγ). The expression of FAS and LPL, which are terminal differentiation markers of mature adipocytes, was also reduced in the 3T3-L1 adipocytes treated with dichloromethane fractions from I. verum Hooker fil. In addition, the treatment significantly inhibited mitotic clonal expansion, which is essential for adipocyte differentiation, by arresting the G1 phase of the cell cycle. Taken together, these results suggest that dichloromethane fractions from I. verum Hooker fil. may be a natural material with antiobesity effects.

The Effects of Action Learning on Nurses' Problem Solving, Communication, Emotional Creativity and Innovation Behavior (액션러닝이 간호사의 문제해결능력, 의사소통, 정서창의성 및 혁신행동에 미치는 효과)

  • Lee, Sook-Ja;Jang, Keum-Seong
    • The Korean Journal of Health Service Management
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    • v.8 no.2
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    • pp.73-87
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    • 2014
  • The purpose of this study was to investigate the effects of a Action Learning(AL) program in terms of problem solving, communication skills, emotional creativity and innovation behaviors. Design for this was a nonequivalent control group quasi-experimental study. The participants were C-hospital staff nurses in G city (Experimental group=29, Control group=30). The AL program was composed of fourteen sessions in eight weeks. Data were collected and the program was conducted from May. 26 to July. 18, 2008. Data were analyzed with χ2-test, Fisher's exact test, t-test and ANCOVA, and utilized the SPSS win 20.0 program. There were significant increases in problem solving skills, communication skills and emotional creativity in the experimental group compared to the control group. Considering the above results, AL program has proven to be an effective educational program for improving the problem solving, communication skills and emotional creativity of nurses.

The Study of Age-related Skin Pigmentation Changes in Korean Female (한국 여성의 연령에 따른 색소 침착 변화 연구)

  • Myeongryeol Lee;Yuchul Jung;Byung-Fhy Suh;Eunjoo Kim
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.49 no.2
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    • pp.177-182
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    • 2023
  • Since facial skin pigmentation is one of the visual characteristics of skin aging, it is important to evaluate skin pigmentation in the cosmetics and aesthetic fields. Several groups have investigated and developed the image analysis methods for skin pigmentation and some of the groups reported the age-related changes of the number and size of facial pigmented spots. However, they didn't show the changes of the number and size of pigment spots by defined size, and there is no report for Korean female regarding pigmentation. A total of 194 Korean females aged 20 ~ 79 (48.97 ± 17.11 years) were analyzed for the number, size, and intensity of pigmented spots using various filters such as large high-pass filter and median filter in their digital facial images. There were significant correlations between age and total pigmented spot number (No.), size, and intensity (I) (pearson's correlation coefficient r = 0.688, r = 0.645, r = -0.563), and significant correlations were also observed between the number and intensity of pigmented spots of different sizes. According to the ANOVA results, there were significant differences in the percentage of spot size of 2 ~ 4 mm2 and > 20 mm2 between 20's and 70's. In other words, with aging, pigmentation increases in the facial skin, and the large increase in pigmentation is particularly noticeable in Korean women.